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Dengue outbreaks in Divinopolis,south‐eastern Brazil and the geographic and climatic distribution of Aedes albopictus and Aedes aegypti in 2011–2012 下载免费PDF全文
Martinelle Ferreira da Rocha Taranto José Eduardo Marques Pessanha Michelli dos Santos Ana Cláudia dos Santos Pereira Andrade Vidyleison Neves Camargos Stênio Nunes Alves Cláudia Di Lorenzo Oliveira Alex Gutterres Taranto Luciana Lara dos Santos José Carlos de Magalhães Erna Geessien Kroon Leandra Barcelos Figueiredo Betânia Paiva Drumond Jaqueline Maria Siqueira Ferreira 《Tropical medicine & international health : TM & IH》2015,20(1):77-88
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Choosing the optimal method of blood pressure measurement for limited‐resource rural communities in the “Community Health Assessment Program—Philippines” 下载免费PDF全文
Dale Guenter MD MPH Ricardo Angeles MD MPH MHPEd PhD Janusz Kaczorowski BA MA PhD Gina Agarwal MBBS PhD Fortunato L. Cristobal MD MPH MHPEd Rosemarie Arciaga MD MSc John F. Smith PhD Pattapong Kessomboon MD PhD Faical Jarraya MD Rodelin Agbulos MD MPH Floro Dave Arnuco MD MPH Jerome Barrera MD Susan Dimitry BA Elgie Gregorio MD MPH Servando Halili PhD Jr Norvie T. Jalani MD MPH Nusaraporn Kessomboon BScPharm MSc PhD Maita Ladeza MD Lisa Dolovich BScPhm PharmD MSc 《Journal of clinical hypertension (Greenwich, Conn.)》2017,19(9):899-903
The Community Health Assessment Program—Philippines (CHAP‐P) is an international collaboration of investigators whose aim is to adapt a previously proven Canadian community‐based cardiovascular awareness and prevention intervention to the Philippines and other low‐middle–income countries. Choosing a method of blood pressure measurement for the research program presents a challenge. There is increasing consensus globally that blood pressure measurement with automated devices is preferred. Recommendations from low‐middle–income countries, including the Philippines, are less supportive of automated blood pressure devices. The value placed on factors including device accuracy, durability, cost, energy source, and complexity differ with local context. Our goal was to support the progress of local policy concerning blood pressure measurement while testing a comprehensive approach to community‐based screening for cardiovascular risk. The authors describe the challenges in making a choice of blood pressure device and the approach to determine optimal method of measurement for our research program. 相似文献
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William Kuan Kenneth Dulnuan Maya E. Guglin Hanine El Haddad Andrew R. Kolodziej Andrew Leventhal Navin Rajagopalan 《Transplant infectious disease》2019,21(6)
To our knowledge, no cases of Bartonella henselae endocarditis leading to subsequent heart transplantation salvage therapy have been published. We present a case of a 29‐year‐old man with cat‐inflicted B henselae endocarditis and concurrent worsening heart failure, who then underwent successful heart transplantation 50 days following diagnosis. Treatment and monitoring strategies used in this patient are discussed. Furthermore, we review literature related to heart transplantation salvage therapy for endocarditis due to other intracellular pathogens. 相似文献
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Recent studies have associated genetic variation near the interleukin 28B (IL28B/IFN‐λ3) gene with natural clearance of the hepatitis C virus (HCV) infection, and a common variant in the DEP domain containing 5 (DEPDC5) locus on chromosome 22 has been shown to affect susceptibility to hepatocellular carcinoma (HCC) in Japanese individuals with chronic HCV infection. This study was conducted to determine whether polymorphisms near or in interferon‐lambda (IFN‐λs) genes and their receptor genes such as interleukin 28 receptor, alpha (IL28RA) and interleukin 10 receptor, beta (IL10RB) as well as p21_activated kinases 4 (PAK4) and iron/zinc purple acid phosphatase‐like protein (PAPL), which are locate upstream of IFN‐λs, and lastly the DEPDC5 gene are associated with hepatitis B virus‐related liver disease in Han Chinese. The study subjects included 507 normal healthy controls, 350 individuals with natural clearance of HBV and 792 HBV‐infected patients. The patients were categorized into 157 inactive carriers (Case I), 216 active carriers (Case II), 111 cirrhotics (Case III) and 308 HCC patients (Case IV) subgroups. Seven single nucleotide polymorphisms (SNPs) were genotyped using the Matrix‐assisted Laser Desorption/Ionisation mass spectrometric (MALDI‐TOF MS) SNP genotyping assay. Rs423058 upstream of PAPL, rs2834167 in IL10RB and rs1012068 in DEPDC5 were associated with chronic HBV status, HBV natural clearance and the presence of HCC (P = 0.0004–0.024), respectively. PAPL, IL10RB and DEPDC5 polymorphisms have an impact on progression of HBV‐related liver disease. However, IFN‐λs genes as a tool to differentiate between different clinical courses of HBV infection were not useful in the Han Chinese population. 相似文献
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J. Horan K. Dellicarpini S.‐W. Pak T. Daly B. Samstein T. Kato J.C. Emond J.V. Guarrera 《Transplant infectious disease》2012,14(3):311-315
In solid organ transplantation, the disparity between donor supply and patients awaiting transplant continues to increase. The organ shortage has led to relaxation of historic contraindications to organ donation. A large percentage of deceased organ donors have been subjected to traumatic injuries, which can often result in intervention that leads to abdominal packing and intensive care unit resuscitation. The donor with this “open abdomen” (OA) presents a situation in which the risk of organ utilization is difficult to quantify. There exists a concern for the potential of a higher risk for both bacterial and fungal infections, including multidrug‐resistant (MDR) pathogens because of the prevalence of antibiotic use and critical illness in this population. No recommendations have been established for utilization of organs from these OA donors, because data are limited. Herein, we report a case of a 21‐year‐old donor who had sustained a gunshot wound to his abdomen, resulting in a damage‐control laparotomy and abdominal packing. The donor subsequently suffered brain death, and the family consented to organ donation. A multiorgan procurement was performed with respective transplantation of the procured organs (heart, liver, and both kidneys) into 4 separate recipients. Peritoneal swab cultures performed at the time of organ recovery grew out MDR Pseudomonas aeruginosa on the day after procurement, subsequently followed by positive blood and sputum cultures as well. All 4 transplant recipients subsequently developed infections with MDR P. aeruginosa, which appeared to be donor‐derived with similar resistance patterns. Appropriate antibiotic coverage was initiated in all of the patients. Although 2 of the recipients died, mortality did not appear to be clearly associated with the donor‐derived infections. This case illustrates the potential infectious risk associated with organs from donors with an OA, and suggests that aggressive surveillance for occult infections should be pursued. 相似文献
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Vector competence of Malaysian Aedes albopictus with and without Wolbachia to four dengue virus serotypes 下载免费PDF全文
Sylvia Joanne Indra Vythilingam Boon‐Teong Teoh Cherng‐Shii Leong Kim‐Kee Tan Meng‐Li Wong Nava Yugavathy Sazaly AbuBakar 《Tropical medicine & international health : TM & IH》2017,22(9):1154-1165
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Interventions to significantly improve service uptake and retention of HIV‐positive pregnant women and HIV‐exposed infants along the prevention of mother‐to‐child transmission continuum of care: systematic review 下载免费PDF全文
Alexandra C. Vrazo Jacqueline Firth Anouk Amzel Rebecca Sedillo Julia Ryan B. Ryan Phelps 《Tropical medicine & international health : TM & IH》2018,23(2):136-148
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Takahisa Hirose Takeshi Ogihara Shusaku Tozaka Sami Kanderian Hirotaka Watada 《Journal of diabetes investigation.》2013,4(3):287-296
Aims/Introduction
Many patients with diabetes now use 5‐, 6‐ or 8‐mm needles for insulin injection. However, it is unclear whether needle length, particularly for shorter needles, affects the pharmacokinetic properties of insulin.Materials and Methods
This was a three‐way, randomized, cross‐over, single‐center study involving 12 healthy Japanese adult males (age 27.4 ± 4.14 years; weight 64.2 ± 5.2 kg; body fat percentage 18.2 ± 1.5%). Participants received a subcutaneous (abdomen) dose of insulin lispro (1.5 U for participants weighing 55 to <65.0 kg; 2.0 U for participants weighing 65.0 to <80.0 kg) delivered using a 32‐G × 4 mm (32G × 4), 31‐G × 8 mm (31G × 8) or 32‐G × 6 mm (32G × 6) needle with a 3–7‐day washout between doses. Pharmacokinetic parameters of exogenous insulin were identified using non‐linear least squares, where the total insulin concentration was fit to the measured plasma insulin concentration using an overall combined model that accounted for C‐peptide/insulin secretion in addition to the injected dose.Results
Maximum concentration and area under the curve for 0 to infinity min for insulin were bioequivalent for the 32G × 4 needle relative to the 32G × 6 and the 31G × 8 needles. The time to the maximum insulin concentration was bioequivalent for the 32G × 4 needle relative to the 32G × 6 needle, but not the 31G × 8 needle.Conclusions
The use of 4‐mm needles is unlikely to change the pharmacokinetic properties of insulin when injected subcutaneously in adults. This trial was registered with UMIN‐CTR (no. UMIN000004469). 相似文献15.
Low‐density lipoprotein and other predictors of response with telaprevir‐based therapy in treatment‐experienced HCV genotype 1 patients: REALIZE study 下载免费PDF全文
Thomas Berg Pietro Andreone Stanislas Pol Stuart Roberts Zobair Younossi Moises Diago Eric J. Lawitz Roberto Focaccia Graham R. Foster Andrzej Horban Isabelle Lonjon‐Domanec Ralph DeMasi Gaston Picchio Donghan Luo Sandra De Meyer Stefan Zeuzem 《Liver international》2015,35(2):448-454
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Priscilla A. van Riet Djuna L. Cahen Katharina Biermann Bettina Hansen Alberto Larghi Guido Rindi Giovanni Fellegara Paolo Arcidiacono Claudio Doglioni Nicola Liberta Decarli Julio Iglesias‐Garcia Ihab Abdulkader Hector Lazare Iglesias Masayuki Kitano Takaaki Chikugo Satoru Yasukawa Hans van der Valk Nam Quoc Nguyen Andrew Ruszkiewicz Marc Giovannini Flora Poizat Schalk van der Merwe Tania Roskams Erwin Santo Silvia Marmor Kenneth Chang Fritz Lin James Farrell Marie Robert Juan Carlos Bucobo Alan Heimann Francisco Baldaque‐Silva Carlos Fernndez Moro Marco J. Bruno 《Digestive endoscopy》2019,31(6):690-697
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Comparison of glucose‐lowering agents after dual therapy failure in type 2 diabetes: A systematic review and network meta‐analysis of randomized controlled trials 下载免费PDF全文
Francesco Zaccardi MD Nafeesa N. Dhalwani PhD Jolyon Dales BM BS Hamid Mani PhD Kamlesh Khunti FRCGP Melanie J. Davies FRCP David R. Webb FRCP 《Diabetes, obesity & metabolism》2018,20(4):985-997