Clear-cell chondrosarcoma with elevated alkaline phosphatase,mistaken for osteosarcoma on biopsy

 This paper report a case of a pelvic clear-cell chondrosarcoma that was initially diagnosed as clear-cell osteosarcoma after needle biopsy. Preoperatively, laboratory studies revealed an elevated alkaline phosphatase and needle biopsy showed clear cells producing osteoid. Internal hemipelvectomy was performed and final pathology was most consistent with clear-cell chondrosarcoma, despite a negative S-100 immunohistochemical stain. Distinguishing between these two entities is clinically important because treatment differs. In this case, the patient did not receive pre- or postoperative chemotherapy and is disease free more than 2 years later.     

Unusual metastatic chondrosarcoma detected with bone scintigraphy

A case is presented of a scapular chondrosarcoma which showed intense uptake of Tc99m MDP in the primary tumour and in pleural and osseous metastases. Additionally, there was intense visualization of the malignant pleural effusion. The bone scintigraphy correctly diagnosed the extent of the involvement. This finding is unusual because chondrosarcomas in such a disseminated state are relatively rare.     

Unusual metastatic chondrosarcoma detected with bone scintigraphy

A case is presented of a scapular chondrosarcoma which showed intense uptake of Tc99m MDP in the primary tumour and in pleural and osseous metastases. Additionally, there was intense visualization of the malignant pleural effusion. The bone scintigraphy correctly diagnosed the extent of the involvement. This finding is unusual because chondrosarcomas in such a disseminated state are relatively rare.     

Clear cell chondrosarcoma of bone

We report 8 cases of clear cell chondrosarcoma from 350 cases of chondrosarcoma (2.2%) seen at Istituto Rizzoli. The lesion is always low grade in nature and occurs in an epiphyseal location, usually in the proximal femur or humerus. This relatively inaccessible location may hinder the exact diagnosis. Wide resection is the treatment of choice, although 3 of our patients underwent intralesional or marginal procedures. At present all patients are free of disease. However, a longer follow-up is essential because of the slow-growing nature of this sarcoma.     

骨转移瘤漏误诊的影像学分析

目的借鉴漏误诊病例的经验教训,提高对本病的影像诊断水平。方法回顾性分析18例经手术病理证实的影像漏误诊骨转移瘤。结果骨转移瘤病例以多发,溶骨为主。影像检查漏误诊分别为：X线8例,CT2例。结论X线、CT是检查骨转移瘤重要手段,但有一定限度,条件许可时应尽早做MRI检查,并做必要的鉴别诊断。     

去分化软骨肉瘤的影像分析

目的分析去分化软骨肉瘤的X线及CT表现，探讨去分化成分的X线、CT表现特点。方法回顾性分析13例去分化软骨肉瘤的X线及CT表现，并结合临床及组织学特点进行分析研究。结果去分化软骨肉瘤不仅具有典型软骨肉瘤的表现，而且还具有去分化成分的影像特点。13例中8例显示有骨化，11例有骨膜反应，12例有软组织肿快，10例有钙化，其中8例钙化位于病灶中央部位。结论去分化软骨肉瘤具有典型软骨肉瘤所不具备的去分化成分的影像特点，认识这些特殊的影像特点有助于提高对该病的正确诊断。     

Metastatic prostatic pulmonary nodules with normal bone image

Asymptomatic prostatic carcinoma presented as multiple bilateral pulmonary nodules in a patient without any evidence of skeletal involvement by normal bone image. Percutaneous biopsy provided the initial clue to diagnosis. We recommend that asymptomatic prostatic carcinoma be included in the differential diagnosis of pulmonary nodules, even when there is no evidence of skeletal metastasis.     

Dedifferentiated chondrosarcoma of bone with leiomyosarcomatous mesenchymal component: a case report

Dedifferentiated chondrosarcomas are well-described aggressive tumors arising from low-grade chondrosarcomas and containing high-grade mesenchymal sarcomatous components. These tumors are important to consider in the differential diagnosis of well-defined lytic lesions in the pelvis associated with large soft-tissue components. We present the plain film, computed tomographic, and angiographic findings of the first such reported tumor containing a leiomyosarcomatous component.     

Desmoid tumor of the abdominal wall. Echographic and CT aspects

Desmoid tumors are rare tumors of the anterior abdominal wall. They are easily accessible to sonography and computed tomography because of their superficial situation. We must know the signs which can call up this diagnosis, particularly sonographic signs. We report one case with usual radiologic aspects of these tumors.     

Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma

Mesenchymal chondrosarcoma is a rare but aggressive, high-grade malignancy of primitive cartilage-forming mesenchyme that arises most commonly from skeletal sites. Although there are radiological findings suggestive of the diagnosis, imaging features often overlap with those of other skeletal sarcomas. The definitive diagnosis relies on the histological finding of a typical bimorphic appearance, consisting of nests of small, round, poorly differentiated cells and more mature cartilaginous tissue. To highlight this, we present the case of a 21-year-old man who was referred to our institution with a history of right knee pain. Initial imaging and histological evaluation of a core biopsy of the lesion suggested osteosarcoma of the distal right femur; after review, however, the correct diagnosis of mesenchymal chondrosarcoma was made. Adequate tissue sampling and thorough histological evaluation of biopsy specimens is vital for the accurate diagnosis of primary bone malignancies, especially those of chondroid origin.     

Desmoid tumor of the mesentery. An uncommon cause of ureteral obstruction]

Desmoid tumors are rare lesions with a local invasive potential and a risk of recurrence considered as benign due to the absence of metastases. They are included in fibromatoses and may be associated with Gardner's syndrome. The authors report an unusual case, in a 26 year old man, of a desmoid tumor invading ileon, right colon, appendix and the right ureter and responsible of a ureteral obstruction. Etiologic factors (traumatic, hormonal, auto-immune...) are discussed. The treatment of choice to lower the risk of recurrence is the complete surgical removal of the tumor.