Oral use of biotin in seborrhoeic dermatitis of infancy: a controlled trial.

A double-blind cross-over trial of biotin given by mouth in the treatment of seborrhoeic dermatitis of infancy did not show a statistically significant advantage of biotin over placebo.     

嗜酸粒细胞性支气管炎不是一种独立的疾病

嗜酸粒细胞性支气管炎（EB）是一种独立的疾病吗？答案是否定的，现有的证据也不支持。     

Why alcoholism is not a disease.

OBJECTIVE: To expound the argument that alcoholism (or "problem drinking") is not best regarded as a disease. SUMMARY: Excessive drinking can cause physical disease and involve physical dependence without therefore being a disease itself. The "disease concept" of alcoholism is not needed to justify medical intervention or a caring approach to those who are dependent on alcohol. There is a specific and a general version of the disease concept of alcoholism. The specific disease concept, associated mainly with the Fellowship of Alcoholics Anonymous, is contradicted by empirical evidence and unhelpful for preventive and treatment responses to problem drinking, especially for the effort to detect and modify problem drinking at an early stage. The more general disease concept shares these disadvantages and is also ineffective in engendering sympathetic attitudes towards problem drinkers among the general public. It is more useful to view problem drinking as the result of the interaction between the individual's personality and the social context in which he or she has learned how to drink. CONCLUSION: For an effective and compassionate societal response to problem drinking, the disease model of alcoholism should be replaced by a social learning perspective.     

医疗技术主义不是医学哲学的应当

医疗技术主义追求利润极大化,抹杀了医学理性精神和公平的医疗消费原则,造成了医学目的的困惑、医疗困难和医患双方的固有矛盾,违背了医学哲学应当的根本所在.医疗技术主义不是医学哲学的应当,对卫生行业进行先进性教育,确立相应的约束和制衡机制,籍以有效遏制医疗技术主义已经刻不容缓.     

Assent is not consent

A recent article from Archives of Disease in Childhood outlined problems with the act of gaining child assent for research participation. However the arguments used in the article are incomplete or misguided. Rather than being harmful, assent should be seen as an ethically-appropriate way in which we can engage with the child about his participation in research. While additional clarification of the concept of assent is needed, the child's family context can provide us with a valuable guide to the way we involve him in the decision-making process.     

When ascites is not ascites

The case is reported of a patient presenting with ascites and acute renal failure resulting from spontaneous rupture of the urinary bladder, 30 years after the successful initial treatment of childhood rhabdomyosarcoma. The delay in the presentation until the patient began to experience the symptoms due to urinary ascites, the diagnostic dilemma because of the rarity of the condition, and the possible aetiologies are discussed.