共查询到20条相似文献,搜索用时 15 毫秒
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Self‐Reported and Interviewer‐Rated Oral Health in Patients With Schizophrenia,Bipolar Disorder,and Major Depressive Disorder 下载免费PDF全文
Xin Ma MD Helen F. K. Chiu FRCPsych Christoph U. Correll MD Gabor S. Ungvari MD PhD Ying‐Qiang Xiang MD PhD Kelly Y. C. Lai MRCPsych Xiao‐Lan Cao MD Yan Li MD Bao‐Liang Zhong MD Ka In Lok MEd MNs Yu‐Tao Xiang MD PhD 《Perspectives in psychiatric care》2016,52(1):4-11
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Fu‐Chun Zhou MD PhD Yu‐Tao Xiang MD PhD Chuan‐Yue Wang MD PhD Faith Dickerson PhD Julie Kreyenbuhl PharmD PhD Gabor S. Ungvari MD PhD Raymond W. C. Au PhD Jing‐Jing Zhou MPhil Yan Zhou BA David Shum PhD David Man PhD Kelly Y. C. Lai MRCPsy Wai‐Kwong Tang MRCPsy Xin Yu MD Helen F. K. Chiu FRCPsy 《Perspectives in psychiatric care》2014,50(2):102-110
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Tae Hyon Ha Ji Sun Kim Jae Seung Chang Sung Hee Oh Ju Young Her Hyun Sang Cho Tae Sung Park Soon Young Shin Kyooseob Ha 《Psychiatry investigation》2012,9(4):339-346
Objective
To compare verbal and visual memory performances between patients with bipolar I disorder (BD I) and patients with bipolar II disorder (BD II) and to determine whether memory deficits were mediated by impaired organizational strategies.Methods
Performances on the Korean-California Verbal Learning Test (K-CVLT) and the Rey-Osterrieth Complex Figure Test (ROCF) in 37 patients with BD I, 46 patients with BD II and 42 healthy subjects were compared. Mediating effects of impaired organization strategies on poor delayed recall was tested by comparing direct and mediated models using multiple regression analysis.Results
Both patients groups recalled fewer words and figure components and showed lower Semantic Clustering compared to controls. Verbal memory impairment was partly mediated by difficulties in Semantic Clustering in both subtypes, whereas the mediating effect of Organization deficit on the visual memory impairment was present only in BD I. In all mediated models, group differences in delayed recall remained significant.Conclusion
Our findings suggest that memory impairment may be one of the fundamental cognitive deficits in bipolar disorders and that executive dysfunctions can exert an additional influence on memory impairments. 相似文献9.
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Suat Ekinci Kadir ?zdel Bedriye ?ncü Bur?in ?olak Hasan Kandemir Saynur Canat 《Psychiatry investigation》2013,10(2):137-142
Objective
To date, the affective temperamental characteristics of adults with attention-deficit hyperactivity disorder (ADHD) have not been studied. The aim of this study is to explore those temperamental characteristics for adults diagnosed with ADHD as measured by the TEMPS-A and then to compare those results with results for individuals diagnosed with bipolar disorder (BD) and with healthy controls.Methods
Forty adults with ADHD, 40 patients with BD, and 40 healthy controls were enrolled in this study. The groups were matched by age and gender. All patients were assessed using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID I), the Hamilton Depression Rating Scale, the Hamilton Anxiety Rating Scale, the Young Mania Rating Scale and the Wender Utah Rating Scale. Subjects'' temperamental characteristics were examined using the Turkish version of the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-auto questionnaire (TEMPS-A).Results
Ten subjects (25%) in the ADHD group and 15 subjects (30%) in the bipolar group had at least one dominant temperament. There was no identifiable dominant temperament in the control group. Compared to the control group, the ADHD group scored higher than other groups on all domains of the TEMPS-A: depressive cyclothymic, irritable and anxious. However, the hyperthymic domain was not higher for this group. Adults with ADHD scored higher on the irritable temperament scale as compared to the BD group. The ADHD and BD groups had similar mean scores for each of the other four temperaments.Conclusion
The adults diagnosed with ADHD in this study had different temperamental characteristics from the control group, and these temperamental characteristics were similar to those of the bipolar patients. Recognizing the role of temperamental characteristics in adults with ADHD may increase our understanding of ADHD. 相似文献11.
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Mansour H Kandil K Wood J Fathi W Elassy M Ibrahim I Salah H Yassin A Elsayed H Tobar S El-Boraie H Eissa A Elhadidy M Ibrahim NE El-Bahaei W Nimgaonkar VL 《Psychiatry investigation》2011,8(3):214-220
Objective
To evaluate reproduction among patients with bipolar I disorder (BP1) or schizophrenia (SZ) in Egypt.Methods
BP1 patients (n=113) were compared with community based, demographically balanced controls (n=124) and SZ patients (n=79, DSM-IV). All participants were evaluated using structured interviews and corroborative data were obtained from relatives. Standard indices of procreation were included in multivariate analyses that incorporated key demographic variables.Results
Control individuals were significantly more likely to have children than BP1 or SZ patients (controls 46.8%, BP1 15.9%, SZ 17.7%), but the BP1-SZ differences were non-significant. The average number of children for BP1 patients (0.37±0.9) and SZ patients (0.38±0.9) was significantly lower than for controls (1.04±1.48) (BP1 vs controls, p<0.001; SZ vs controls, p<0.001). The frequency of marriages among BP1 patients was nominally higher than the SZ group, but was significantly lower than controls (BP1: 31.9% SZ: 27.8% control: 57.3%). Even among married individuals, BP1 (but not SZ) patients were childless more often than controls (p=0.001). The marital fertility, i.e., the average number of children among patients with conjugal relationships for controls (1.8±1.57) was significantly higher than BP1 patients (1.14±1.31, p=0.02), but not significantly different from SZ patients (1.36±1.32, p=0.2).Conclusion
Selected reproductive measures are significantly and substantially reduced among Egyptian BP1 patients. The reproductive indices are similar among BP1 and SZ patients, suggesting a role for general illness related variables. Regardless of the cause/s, the impairment constitutes important, under-investigated disability. 相似文献13.
Fischer EP McCarthy JF Ignacio RV Blow FC Barry KL Hudson TJ Owen RR Valenstein M 《Community mental health journal》2008,44(5):321-330
Inconsistent service use for schizophrenia and bipolar disorder is associated with poorer outcomes of care. We analyzed VHA
National Psychosis Registry data for 164,150 veterans with these disorders to identify characteristics associated with 5-year
patterns of survival and with retention in VHA care. Most cohort members (63%) survived the period with no break in VHA healthcare
lasting over 12 months. Inconsistent utilization was associated with younger age, no service-connected disability, and less
physical comorbidity, regardless of diagnosis. The influence of gender and ethnicity on attrition varied by diagnosis and
gap-duration. Variation in attrition by gender and ethnicity warrants additional attention. 相似文献
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Joseph Biederman Gagan Joshi Eric Mick Robert Doyle Anna Georgiopoulos Paul Hammerness Meghan Kotarski Courtney Williams Janet Wozniak 《CNS Neuroscience & Therapeutics》2010,16(2):91-102
Aim: To evaluate the safety and efficacy of lamotrigine monotherapy as an acute treatment of bipolar mood elevation in children with bipolar spectrum disorders. Method: This was a 12‐week, open‐label, prospective trial of lamotrigine monotherapy to assess the effectiveness and tolerability of this compound in treating pediatric bipolar disorder. Assessments included the Young Mania Rating Scale (YMRS), Clinical Global Impressions‐Improvement scale (CGI‐I), Children's Depression Rating Scale (CDRS), and Brief Psychiatric Rating Scale (BPRS). Adverse events were assessed through spontaneous self‐reports, vital signs weight monitoring, and laboratory analysis. Results: Thirty‐nine children with bipolar disorder (YMRS at entry: 31.6 ± 5.5) were enrolled in the study and 22 (56%) completed the 12‐week trial. Lamotrigine was slowly titrated to an average endpoint dose of 160.7 ± 128.3 in subjects <12 years of age (N = 22) and 219.1 ± 172.2 mg/day in children 12–17 years of age (N = 17). Treatment with lamotrigine was associated with statistically significant levels of improvement in mean YMRS scores (?14.9 ± 9.7, P < 0.001) at endpoint. Lamotrigine treatment also resulted in significant improvement in the severity of depressive, attention‐deficit/hyperactivity disorder (ADHD), and psychotic symptoms. Lamotrigine was generally well tolerated with marginal increase in body weight (47.0 ± 18.0 kg vs. 47.2 ± 17.9 kg, P= 0.6) and was not associated with abnormal changes in laboratory parameters. Several participants were discontinued due to skin rash; in all cases, the rash resolved shortly after discontinuation of treatment. No patient developed Steven Johnson syndrome. Conclusions: Open‐label lamotrigine treatment appears to be beneficial in the treatment of bipolar disorder and associated conditions in children. Future placebo‐controlled, double‐blind studies are warranted to confirm these findings. 相似文献
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Ji Seon You Chan Woo Lee Ji Yoon Park Yoonjeong Jang Hyeona Yu Joohyun Yoon Sarah Soonji Kwon Sunghee Oh Yun Seong Park Hyun A Ryoo Jong Hun Lee Daseul Lee Jakyung Lee Yeoju Kim Nayoung Cho Hong Kyu Ihm C. Hyung Keun Park Yeong Chan Lee Hong-Hee Won Hyo Shin Kang Ji Hyun Beak Tae Hyon Ha Woojae Myung 《Psychiatry investigation》2022,19(11):909
Objective Mood disorder and borderline personality pathology (BPP) are frequently comorbid and relate to childhood trauma. We investigated the relationship between childhood trauma and BPP features in mood disorder patients versus controls. Methods A total of 488 mood disorder patients, particularly major depressive disorder (MDD), bipolar I disorder (BD I), and bipolar II disorder (BD II), and 734 controls were included. We examined between-group BPP-related differences and correlated between BPP and childhood trauma using the Childhood Trauma Questionnaire-Short Form (CTQ) and the Personality Assessment Inventory–Borderline Features Scale. Results BD II patients showed significantly higher BPP. Emotional abuse and neglect were prominently associated with BPP, while affective instability and negative relationships exhibited a stronger association with childhood trauma. We also found a positive relationship between childhood trauma and BPP in MDD, BD I, and BD II patients. Conclusion The findings of the present study imply that BPP features are more likely to be found in patients with BD II than BD I or MDD. Mood disorder patients with severe childhood trauma may have higher BPP features. Thus, further study of the relationship between childhood trauma and BPP features could improve the therapeutic approaches and help understand patients with mood disorders. 相似文献
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Michel Maziade Nancie Rouleau Chantal M��rette Caroline Cellard Marco Battaglia Cecilia Marino Val��rie Jomphe Elsa Gilbert Am��lie Achim Roch-Hugo Bouchard Thomas Paccalet Marie-Eve Paradis Marc-Andr�� Roy 《Schizophrenia bulletin》2011,37(6):1218-1228
Objective: Memory deficits have been shown in patients affected by schizophrenia (SZ) and bipolar (BP)/mood disorder. We recently reported that young high-risk offspring of an affected parent were impaired in both verbal episodic memory (VEM) and visual episodic memory (VisEM). Understanding better the trajectory of memory impairments from childhood to adult clinical status in risk populations is crucial for early detection and prevention. In multigenerational families densely affected by SZ or BP, our aim was to compare the memory impairments observed in young nonaffected offspring with memory functioning in nonaffected adult relatives and patients. Methods: For 20 years, we followed up numerous kindreds in the Eastern Québec population. After having characterized the Diagnostic and Statistical Manual of Mental Disorders phenotypes, we assessed cognition (N = 381) in 3 subsamples in these kindreds and in controls: 60 young offspring of a parent affected by SZ or BP, and in the adult generations, 92 nonaffected adult relatives and 40 patients affected by SZ or BP. VEM was assessed with the California Verbal Learning Test and VisEM with the Rey figures. Results: The VEM deficits observed in the offspring were also found in adult relatives and patients. In contrast, the VisEM impairments observed in the young offspring were present only in patients, not in the adult relatives. Conclusion: Implications for prevention and genetic mechanisms can be drawn from the observation that VEM and VisEM would show distinct generational trajectories and that the trajectory associated with VisEM may offer a better potential than VEM to predict future risk of developing the disease. 相似文献
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Jolanta Zanelli Abraham Reichenberg Sven Sandin Craig Morgan Paola Dazzan Izabela Pilecka Tiago Reis Marques Kevin Morgan Allan H Young Josephine Mollon 《Schizophrenia bulletin》2022,48(3):590
Few studies have comprehensively examined the profile of cognitive functioning in first episode psychosis patients throughout the lifespan, and from first episode to chronic stage. We assessed functioning in general and specific cognitive functions, comparing both schizophrenia (N = 64) and bipolar I (N = 19) patients to controls (N = 103). Participants were from a population-based, case-control study of first episode psychosis patients, who were followed prospectively up to 10 years post first admission. A cognitive battery was administered at baseline and follow-up. By combining longitudinal and cross-sectional data, we were able to examine the cognitive profile of patients and controls throughout the entire age range of our sample (16–65). Schizophrenia patients exhibited widespread declines in IQ, executive function, visual memory, language ability, and verbal knowledge. However, the ages at which these declines occurred differed between functions. Deficits in verbal memory, working memory, processing speed, and visuospatial ability, on the other hand, were present at the first episode, and remained relatively static thereafter. Bipolar I patients also showed declines in IQ, verbal knowledge, and language ability, albeit at different ages to schizophrenia patients and only in verbal functions. Deficits on measures of verbal memory, processing speed, and executive function remained relatively static. Thus, both schizophrenia and bipolar I patients experienced cognitive decline in general and specific functions after the first episode, but the age at which these declines occurred differed between disorder and function. Cognitive remediation efforts may be most fruitful when targeting individual functions during specific time periods throughout adulthood. 相似文献