中草药喷雾对烧伤后创面色素沉着疗效观察

采用中草药离子喷雾加中药祛斑面膜，作不同深度烧伤创面愈后的康复护理，将皮肤美容技术用于烧伤后色素沉着的康复治疗100例，皆获得较好效果，有效率100％，实践证明应用本法有利于烧伤后及植皮后色素沉着减退。     

烧伤后面部色素沉着中西医结合治疗的临床效果探讨

目的 探讨和评价中西医结合治疗烧伤后面部色素沉着的临床疗效.方法 168例烧伤后面部色素沉着患者,给予中药面膜及低能量密度Q开关Nd:YAG激光治疗,其中局部应用中药面膜者56例(A组)、单纯照射低能量密度Q开关Nd:YAG激光56例(B组)、中药面膜联合低能量密度Q开关Nd:YAG激光治疗56例(C组).结果 138例患者色素沉着均有不同程度改善,其中C组最明显,56例患者中14例色素沉着治愈,26例显著改善,14例褪色有效,2例无明显变化,有效率为96.43%;A组与B组有效率分别为71.43%和78.57%.结论 以上3种方法 均能改善烧伤后皮肤色素沉着,其中中药面膜联合低能量密度Q开关Nd:YAG激光治疗效果最显著.     

透皮促渗方法联合应用的研究进展

透皮给药系统具有传统给药方式不可比拟的优势。但由于药物的低渗透量，使其应用受到一定限制。各种物理的、化学的促渗方法，包括透皮吸收促进剂、超声导入法、离子导入法、电穿孔法等可改善皮肤透过性，增加药物的透皮速率。而且几种方法联合应用的促渗效果更加显著。本文总结了近年来各种促渗方法联合应用的研究进展。     

面膜联合超声导入治疗面部烧伤后色素沉着75例疗效观察

<正>烧伤创面愈合后常会出现不同程度的色素沉着,早期消除烧伤部位色素沉着是烧伤康复的重要问题[1]。我科于2012年5月至2013年4月采用中药面膜联合超声导入氢醌乳膏治疗烧伤后皮肤色素沉着,取得较好治疗效果,现分析报告如下。资料与方法1临床资料选择我科面颈部烧伤创面愈合但存有色素沉着患者150例,其中男92例,女58例。年龄15~56岁,平均     

应用美容方法治疗面部烧伤后色素沉着

面部烧伤创面愈合 1～ 2周左右 ,烧伤部位会出现褐色或黑褐色色素沉着。面部色素沉着不仅影响外表美观 ,而且直接影响患者的心理 ,给患者造成极大的心理压力。针对这一现象 ,我科自 1994年开始 ,将美容方法应用于烧伤患者烧伤后的恢复 ,即用离子喷雾机、离子导入机、色素渗透液、中药祛斑面膜来治疗烧伤后面部色素沉着 ,取得了良好的效果 ,现将方法及经验介绍如下。1　临床资料本组 10 8例患者 ,男 69人 ,女 39人 ,年龄最大者64岁 ,最小者 5岁。其中Ⅰ度烧伤 8例 ,浅Ⅱ度烧伤5 9例 ,深Ⅱ度烧伤 4 1例。治疗 10次为 1个疗程。一般Ⅰ度烧伤 1…     

探讨烧伤创面愈合后皮肤的美容护理

目的探讨烧伤后创面愈合皮肤的美容护理方法。方法选择我院接受皮肤烧伤愈合治疗31例患者为例,其中浅二度烧伤患者有9例,深二度烧伤患者有13例,三度烧伤患者9例,通过皮肤护理、局部按摩等方法实施美容护理。探究患者护理效果。结果通过美容护理,9例浅二度创面烧伤患者经过2个疗程的美容护理治疗,基本治愈率为88.9%,13例二度烧伤患者治疗4个疗程后,基本治愈率为76.9%,9例三度烧伤患者经过5个疗程的治疗后基本治愈率为77.8%。结论患者烧伤皮肤愈合后进行美容护理可以控制色素沉着,减少瘢痕,改善患者创面外观,而且还能改善肤色,对烧伤皮肤的康复一定程度上有促进作用,值得推广。     

不同物理促透技术对芥子碱硫氰酸盐体外透皮吸收的影响

目的 比较微针、超声导入和离子导入3种物理方式促药物吸收技术对芥子碱硫氰酸盐(ST)体外透皮吸收的效果,探讨不同物理方式促进透皮吸收的规律.方法 采用改良Franz扩散池和SD大鼠腹部皮肤,分别在微针、超声导入或离子导入条件下进行透皮实验.以2 mg/ml ST水溶液为供体溶液,定时从接收池中取样,用高效液相色谱法(HPLC)测定不同时间点样品中药物含量,计算累积透过量和稳态透皮吸收速度.取各促透皮技术处理12 h后的皮肤制作病理切片,观察不同促透技术对皮肤结构的影响,探讨其促吸收机制.结果 单纯透皮条件下,ST累积透过量较少.不同促透技术对ST有较明显促透效果,排序如下:微针>超声导入>离子导入.微针在皮肤表面形成实质性孔道,促进ST透皮吸收的效果最明显.超声导入通过扰乱皮肤角质层的紧密结构促透.离子导入对皮肤结构影响较小.结论 本研究为不同透皮给药促透技术的选择提供了依据.     

直流电药物离子导入法在眼科治疗中临床应用价值探讨

目的 评价直流电药物离子导入法在眼科治疗中的临床疗效和应用价值.方法 将108例眼科疾病患者随机分为直流电药物离子导入组（治疗组）和阿司匹林抗凝药物治疗和维生素B族药物治疗组（对照组）各54例.治疗组用直流电药物离子导入法治疗,对照组患者应用相应临床治疗方法.治疗前后分别检查局部症状和不同疾病的相应指标.结果 治疗组总有效率为91.3%,优于对照组的54.3%（P〈0.01）.结论 直流电药物离子导入中药法是治疗眼科疾病的有效方法.     

脉冲强光治疗浅表性色素斑的疗效观察

目的 讨论脉冲强光(IPL)治疗浅表性色素斑的疗效.方法 脉冲强光治疗患者共计316例,其中雀斑198例,色素沉着明显的脂溢性角化症118例.每4周治疗一次,三次为1疗程.结果 疗效显著,治疗一次后患处改善度达50%以上,医生总体满意率96.7%.患者满意率95.3%.结论 应用脉冲强光治疗浅表性色素斑短期效果良好,不良反应小.     

中药离子导入治疗肺炎的临床观察

目的 观察中药离子导入治疗肺炎的疗效.方法 局部外用中药煎液离子导入治疗肺炎58例,并设对照组,观察临床症状及肺炎渗出影像的变化情况.结果 中药离子导入治疗肺炎的治疗总有效率为100%,对照组为94.8%;中药离子导入组肺炎渗出影像吸收率84.5%,对照组63.8%.结论 中药离子导人治疗肺炎配合药物治疗肺炎的渗出影像吸收优于单用药物治疗.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.