共查询到20条相似文献,搜索用时 250 毫秒
1.
Liu T Lungu OV Waechter T Willingham DT Ashe J 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2007,180(2):273-280
There is a significant overlap between the processes and neural substrates of spatial cognition and those subserving memory
and learning. However, for procedural learning, which often is spatial in nature, we do not know how different forms of spatial
knowledge, such as egocentric and allocentric frames of reference, are utilized nor whether these frames are differentially
engaged during implicit and explicit processes. To address this issue, we trained human subjects on a movement sequence presented
on a bi-dimensional (2D) geometric frame. We then systematically manipulated the geometric frame (allocentric) or the sequence
of movements (egocentric) or both, and retested the subjects on their ability to transfer the sequence knowledge they had
acquired in training and also determined whether the subjects had learned the sequence implicitly or explicitly. None of the
subjects (implicit or explicit) showed evidence of transfer when both frames of reference were changed which suggests that
spatial information is essential. Both implicit and explicit subjects transferred when the egocentric frame was maintained
indicating that this representation is common to both processes. Finally, explicit subjects were also able to benefit from
the allocentric frame in transfer, which suggests that explicit procedural knowledge may have two tiers comprising egocentric
and allocentric representations. 相似文献
2.
We used a memory-saccade task to test whether the location of a target, briefly presented before a whole-body rotation in roll, is stored in egocentric or in allocentric coordinates. To make this distinction, we exploited the fact that subjects, when tilted sideways in darkness, make systematic errors when indicating the direction of gravity (an allocentric task) even though they have a veridical percept of their self-orientation in space. We hypothesized that if spatial memory is coded allocentrically, these distortions affect the coding of remembered targets and their readout after a body rotation. Alternatively, if coding is egocentric, updating for body rotation becomes essential and errors in performance should be related to the amount of intervening rotation. Subjects (n = 6) were tested making saccades to remembered world-fixed targets after passive body tilts. Initial and final tilt angle ranged between -120 degrees CCW and 120 degrees CW. The results showed that subjects made large systematic directional errors in their saccades (up to 90 degrees ). These errors did not occur in the absence of intervening body rotation, ruling out a memory degradation effect. Regression analysis showed that the errors were closely related to the amount of subjective allocentric distortion at both the initial and final tilt angle, rather than to the amount of intervening rotation. We conclude that the brain uses an allocentric reference frame, possibly gravity-based, to code visuospatial memories during whole-body tilts. This supports the notion that the brain can define information in multiple frames of reference, depending on sensory inputs and task demands. 相似文献
3.
Gaspare Galati Gina Pelle Alain Berthoz Giorgia Committeri 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2010,206(2):109-120
We review human functional neuroimaging studies that have explicitly investigated the reference frames used in different cortical
regions for representing spatial locations of objects. Beyond the general distinction between “egocentric” and “allocentric”
reference frames, we provide evidence for the selective involvement of the posterior parietal cortex and associated frontal
regions in the specific process of egocentric localization of visual and somatosensory stimuli with respect to relevant body
parts (“body referencing”). Similarly, parahippocampal and retrosplenial regions, together with specific parietal subregions
such as the precuneus, are selectively involved in a specific form of allocentric representation in which object locations
are encoded relative to enduring spatial features of a familiar environment (“environmental referencing”). We also present
a novel functional magnetic resonance imaging study showing that these regions are selectively activated, whenever a purely
perceptual spatial task involves an object which maintains a stable location in space during the whole experiment, irrespective
of its perceptual features and its orienting value as a landmark. This effect can be dissociated from the consequences of
an explicit memory recall of landmark locations, a process that further engages the retrosplenial cortex. 相似文献
4.
Gian Luca Cesa Gian Mauro Manzoni Monica Bacchetta Gianluca Castelnuovo Sara Conti Andrea Gaggioli Fabrizia Mantovani Enrico Molinari Georgina Cárdenas-López Giuseppe Riva 《Journal of medical Internet research》2013,15(6)
Background
Recent research identifies unhealthful weight-control behaviors (fasting, vomiting, or laxative abuse) induced by a negative experience of the body, as the common antecedents of both obesity and eating disorders. In particular, according to the allocentric lock hypothesis, individuals with obesity may be locked to an allocentric (observer view) negative memory of the body that is no longer updated by contrasting egocentric representations driven by perception. In other words, these patients may be locked to an allocentric negative representation of their body that their sensory inputs are no longer able to update even after a demanding diet and a significant weight loss.Objective
To test the brief and long-term clinical efficacy of an enhanced cognitive-behavioral therapy including a virtual reality protocol aimed at unlocking the negative memory of the body (ECT) in morbidly obese patients with binge eating disorders (BED) compared with standard cognitive behavior therapy (CBT) and an inpatient multimodal treatment (IP) on weight loss, weight loss maintenance, BED remission, and body satisfaction improvement, including psychonutritional groups, a low-calorie diet (1200 kcal/day), and physical training.Methods
90 obese (BMI>40) female patients with BED upon referral to an obesity rehabilitation center were randomly assigned to conditions (31 to ECT, 30 to CBT, and 29 to IP). Before treatment completion, 24 patients discharged themselves from hospital (4 in ECT, 10 in CBT, and 10 in IP). The remaining 66 inpatients received either 15 sessions of ECT, 15 sessions of CBT, or no additional treatment over a 5-week usual care inpatient regimen (IP). ECT and CBT treatments were administered by 3 licensed psychotherapists, and patients were blinded to conditions. At start, upon completion of the inpatient treatment, and at 1-year follow-up, patients'' weight, number of binge eating episodes during the previous month, and body satisfaction were assessed by self-report questionnaires and compared across conditions. 22 patients who received all sessions did not provide follow-up data (9 in ECT, 6 in CBT, and 7 in IP).Results
Only ECT was effective at improving weight loss at 1-year follow-up. Conversely, control participants regained on average most of the weight they had lost during the inpatient program. Binge eating episodes decreased to zero during the inpatient program but were reported again in all the three groups at 1-year follow-up. However, a substantial regain was observed only in the group who received the inpatient program alone, while both ECT and CBT were successful in maintaining a low rate of monthly binge eating episodes.Conclusions
Despite study limitations, findings support the hypothesis that the integration of a VR-based treatment, aimed at both unlocking the negative memory of the body and at modifying its behavioral and emotional correlates, may improve the long-term outcome of a treatment for obese BED patients. As expected, the VR-based treatment, in comparison with the standard CBT approach, was able to better prevent weight regain but not to better manage binge eating episodes.Trial Registration
International Standard Randomized Controlled Trial Number (ISRCTN): 59019572; http://www.controlled-trials.com/ISRCTN59019572 (Archived by WebCite at http://www.webcitation.org/6GxHxAR2G) 相似文献5.
Individuals with anorexia nervosa (AN) have a disturbance in the way in which their body is experienced and tend to evaluate negatively their own body and body parts. It is controversial whether these symptoms are secondary to dysfunctions in the neuronal processes related to appetite and emotional regulation or reflect a primary disturbance in the way the body is experienced and remembered. According to the "Allocentric Lock Hypothesis--ALH" (http://dx.doi.org/10.1016/j.mehy.2011.10.039) individuals with AN may be locked to an allocentric (observer view) negative memory of the body that is no more updated by contrasting egocentric representations driven by perception. Recent neuroimaging studies are showing several structural and functional alterations in frame- and memory-related body-image-processing brain circuits that may support ALH. 相似文献
6.
The present study investigated the brain dynamics accompanying spatial navigation based on distinct reference frames. Participants preferentially using an allocentric or an egocentric reference frame navigated through virtual tunnels and reported their homing direction at the end of each trial based on their spatial representation of the passage. Task-related electroencephalographic (EEG) dynamics were analyzed based on independent component analysis (ICA) and subsequent clustering of independent components. Parietal alpha desynchronization during encoding of spatial information predicted homing performance for participants using an egocentric reference frame. In contrast, retrosplenial and occipital alpha desynchronization during retrieval covaried with homing performance of participants using an allocentric reference frame. These results support the assumption of distinct neural networks underlying the computation of distinct reference frames and reveal a direct relationship of alpha modulation in parietal and retrosplenial areas with encoding and retrieval of spatial information for homing behavior. 相似文献
7.
Allocentric versus egocentric spatial memory after unilateral temporal lobectomy in humans 总被引:1,自引:0,他引:1
Thirty patients who had undergone either a right or left unilateral temporal lobectomy (14 RTL; 16 LTL) and 16 control participants were tested on a computerized human analogue of the Morris Water Maze. The procedure was designed to compare allocentric and egocentric spatial memory. In the allocentric condition, participants searched for a target location on the screen, guided by object cues. Between trials, participants had to walk around the screen, which disrupted egocentric memory representation. In the egocentric condition, participants remained in the same position, but the object cues were shifted between searches to prevent them from using allocentric memory. Only the RTL group was impaired on the allocentric condition, and neither the LTL nor RTL group was impaired on additional tests of spatial working memory or spatial manipulation. The results support the notion that the right anterior temporal lobe stores long-term allocentric spatial memories. 相似文献
8.
Ruotolo F Iachini T Postma A van der Ham IJ 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2011,214(4):587-595
This research is about the role of categorical and coordinate spatial relations and allocentric and egocentric frames of reference
in processing spatial information. To this end, we asked whether spatial information is firstly encoded with respect to a
frame of reference or with respect to categorical/coordinate spatial relations. Participants had to judge whether two vertical
bars appeared on the same side (categorical) or at the same distance (coordinate) with respect to the centre of a horizontal bar (allocentric) or with respect to their body midline (egocentric). The key manipulation was the timing of the instructions: one instruction (reference frame or spatial relation) was given
before stimulus presentation, the other one after. If spatial processing requires egocentric/allocentric encoding before coordinate/categorical encoding, then spatial judgements
should be facilitated when the frame of reference is specified in advance. In contrast, if categorical and coordinate dimensions
are primary, then a facilitation should appear when the spatial relation is specified in advance. Results showed that participants
were more accurate and faster when the reference frame rather than the type of spatial relation was provided before stimulus
presentation. Furthermore, a selective facilitation was found for coordinate and categorical judgements after egocentric and
allocentric cues, respectively. These results suggest a hierarchical structure of spatial information processing where reference
frames play a primary role and selectively interact with subsequent processing of spatial relations. 相似文献
9.
Massimiliano Conson Elisabetta Mazzarella Carmela Donnarumma Luigi Trojano 《Neuroscience letters》2012
Motor imagery tasks (hand laterality judgment) are usually performed with respect to a self-body (egocentric) representation, but manipulations of stimulus features (hand orientation) can induce a shift to other's body (allocentric) reference frame. Visual perspective taking tasks are also performed in self-body perspective but a shift to an allocentric frame can be triggered by manipulations of context features (e.g., another person present in the to-be-judged scene). Combining hand laterality task and visual perspective taking, we demonstrated that both stimulus and context features can modulate motor imagery performance. In Experiment 1, participants judged laterality of a hand embedded in a human or non-human silhouette. Results showed that observing a human silhouette interfered with judgments on “egocentric hand stimuli” (right hand, fingers up). In Experiment 2, participants were explicitly required to judge laterality of a hand embedded in a human silhouette from their own (egocentric group) or from the silhouette's perspective (allocentric group). Consistent with previous results, the egocentric group was significantly faster than the allocentric group in judging fingers-up right hand stimuli. These findings showed that concurrent activation of egocentric and allocentric frames during mental transformation of body parts impairs participants’ performance due to a conflict between motor and visual mechanisms. 相似文献
10.
Gaunet F Ittyerah M Rossetti Y 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2007,178(2):167-179
The study investigated pointing at memorized targets in reachable space in congenitally blind (CB) and blindfolded sighted
(BS) children (6, 8, 10 and 12 years; ten children in each group). The target locations were presented on a sagittal plane
by passive positioning of the left index finger. A go signal for matching the target location with the right index finger
was provided 0 or 4 s after demonstration. An age effect was found only for absolute distance errors and the surface area
of pointing was smaller for the CB children. Results indicate that early visual experience and age are not predictive factors
for pointing in children. The delay was an important factor at all ages and for both groups, indicating distinct spatial representations
such as egocentric and allocentric frames of reference, for immediate and delayed pointing, respectively. Therefore, the CB
like the BS children are able to use both ego- and allocentric frames of reference. 相似文献
11.
Hach S Ishihara M Keller PE Schütz-Bosbach S 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2011,212(4):563-574
Analogously to the visual system, somatosensory processing may be segregated into two streams, with the body constituting
either part of the action system or a perceptual object. Experimental studies with participants free from neurological disease
which test this hypothesis are rare, however. The present study explored the contributions of the two putative streams to
a task that requires participants to estimate the spatial properties of their own body. Two manipulations from the visuospatial
literature were included. First, participants were required to point either backward towards pre-defined landmarks on their
own body (egocentric reference frame) or to a forward projection of their own body (allocentric representation). Second, a
manipulation of movement mode was included, requiring participants to perform pointing movements either immediately, or after
a fixed delay, following instruction. Results show that accessing an allocentric representation of one’s own body results
in performance changes. Specifically, the spatial bias shown to exist for body space when pointing backward at one’s own body
disappears when participants are requested to mentally project their body to a pre-defined location in front space. Conversely,
delayed execution of pointing movements does not result in performance changes. Altogether, these findings provide support
for a constrained dual stream hypothesis of somatosensory processing and are the first to show similarities in the processing
of body space and peripersonal space. 相似文献
12.
Spatial hemineglect in humans 总被引:8,自引:0,他引:8
Kerkhoff G 《Progress in neurobiology》2001,63(1):1-27
The paper reviews the main findings of studies of hemispatial neglect after acquired brain lesions in people. The behavioral consequences of experimentally induced lesions in animals and electrophysiological studies, which shed light on the nature of the disorder, are briefly considered. Neglect is behaviorally defined as a deficit in processing or responding to sensory stimuli in the contralateral hemispace, a part of the own body, the part of an imagined scene, or may include the failure to act with the contralesional limbs despite intact motor functions. Neglect in humans is frequently encountered after right parieto-temporal lesions and leads to a multicomponent syndrome of sensory, motor and representational deficits. Relevant findings relating to neglect, extinction and unawareness are reviewed and include the following topics: etiological and anatomical basis, recovery; allocentric, egocentric, object-centered and representational neglect; motor neglect and directional hypokinesia; elementary sensorimotor and associated disorders; subdivisions of space and frames of reference; extinction versus neglect; covert processing of information; unawareness of deficits; human and animal models; effects of sensory stimulation and rehabilitation techniques. 相似文献
13.
Kushiro K Taga G Watanabe H 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2007,183(4):523-529
The visual and vestibular systems begin functioning early in life. However, it is unclear whether young infants perceive the
dynamic world based on the retinal coordinate (egocentric reference frame) or the environmental coordinate (allocentric reference
frame) when they encounter incongruence between frames of reference due to changes in body position. In this study, we performed
the habituation–dishabituation procedure to assess novelty detection in a visual display, and a change in body position was
included between the habituation and dishabituation phases in order to test whether infants dishabituate to the change in
stimulus on the retinal or environmental coordinate. Twenty infants aged 3–4 months were placed in the right-side-down position
(RSDp) and habituated to an animated human-like character that walked horizontally in the environmental frame of reference.
Subsequently, their body position was changed in the roll plane. Ten infants were repositioned to the upright position (UPp)
and the rest, to the RSDp after rotation. In the test phase, the displays that were spatially identical to those shown in
the habituation phase and 90° rotated displays were alternately presented, and visual preference was examined. The results
revealed that infants looked longer at changes in the display on the retinal coordinate than at changes in the display on
the environmental coordinate. This suggests that changes in body position from lying to upright produced incongruence of the
egocentric and allocentric reference frames for perception of dynamic visual displays and that infants may rely more on the
egocentric reference frame. 相似文献
14.
Kaas AL Mier HI 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2006,170(3):403-413
Research has shown that haptic spatial matching at intermanual distances over 60 cm is prone to large systematic errors. The
error pattern has been explained by the use of reference frames intermediate between egocentric and allocentric coding. This
study investigated haptic performance in near peripersonal space, i.e. at intermanual distances of 60 cm and less. Twelve
blindfolded participants (six males and six females) were presented with two turn bars at equal distances from the midsagittal
plane, 30 or 60 cm apart. Different orientations (vertical/horizontal or oblique) of the left bar had to be matched by adjusting
the right bar to either a mirror symmetric (/ \) or parallel (/ /) position. The mirror symmetry task can in principle be
performed accurately in both an egocentric and an allocentric reference frame, whereas the parallel task requires an allocentric
representation. Results showed that parallel matching induced large systematic errors which increased with distance. Overall
error was significantly smaller in the mirror task. The task difference also held for the vertical orientation at 60 cm distance,
even though this orientation required the same response in both tasks, showing a marked effect of task instruction. In addition,
men outperformed women on the parallel task. Finally, contrary to our expectations, systematic errors were found in the mirror
task, predominantly at 30 cm distance. Based on these findings, we suggest that haptic performance in near peripersonal space
might be dominated by different mechanisms than those which come into play at distances over 60 cm. Moreover, our results
indicate that both inter-individual differences and task demands affect task performance in haptic spatial matching. Therefore,
we conclude that the study of haptic spatial matching in near peripersonal space might reveal important additional constraints
for the specification of adequate models of haptic spatial performance. 相似文献
15.
Keira Ball Daniel Smith Amanda Ellison Thomas Schenk 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2010,204(4):585-594
Spatial priming in visual search is a well-documented phenomenon. If the target of a visual search is presented at the same
location in subsequent trials, the time taken to find the target at this repeated target location is significantly reduced.
Previous studies did not determine which spatial reference frame is used to code the location. At least two reference frames
can be distinguished: an observer-related frame of reference (egocentric) or a scene-based frame of reference (allocentric).
While past studies suggest that an allocentric reference frame is more effective, we found that an egocentric reference frame
is at least as effective as an allocentric one (Ball et al. Neuropsychologia
47(6):1585–1591, 2009). Our previous study did not identify which specific egocentric reference frame was used for the priming: participants could
have used a retinotopic or a body-centred frame of reference. Here, we disentangled the retinotopic and body-centred reference
frames. In the retinotopic condition, the position of the target stimulus, when repeated, changed with the fixation position,
whereas in the body-centred condition, the position of the target stimulus remained the same relative to the display, and
thus to the body-midline, but was different relative to the fixation position. We used a conjunction search task to assess
the generality of our previous findings. We found that participants relied on body-centred information and not retinotopic
cues. Thus, we provide further evidence that egocentric information, and specifically body-centred information, can persist
for several seconds, and that these effects are not specific to either a feature or a conjunction search paradigm. 相似文献
16.
González-Burgos I Fletes-Vargas G González-Tapia D González-Ramírez MM Rivera-Cervantes MC Martínez-Degollado M 《Neuroscience research》2012,73(4):321-327
Working memory is a cognitive ability chiefly organized by the prefrontal cortex. Working memory tests may be resolved based on allocentric or egocentric spatial strategies. Serotonergic neurotransmission is closely involved in working memory, but its role in spatial strategies for working memory performance is unknown. To address this issue, prefrontal serotonin depletion was induced to adult male rats, and three days after the behavioral expression of both allocentric and egocentric strategies were evaluated in the "Y" maze and in a crossed-arm maze, respectively. Serotonin depletion caused no effects on allocentric-related behavioral performance, but lesioned rats performed deficiently when the egocentric working memory was evaluated. These results suggest that serotonin may be more closely related with the organization of working memory that uses own movement-guided responses than with that involving the use of external visuospatial signals. Further neurochemical studies are needed to elucidate possible interactions between serotonergic activity and other neurotransmitter systems in the organization of working memory-related allocentric and egocentric strategies. 相似文献
17.
S. Hocherman D. Aharonson B. Medalion I. Hocherman 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1988,73(2):256-262
Summary In the present work we sought to examine the idea that an internalized representation of space can be formed and used in the absence of visual information. To this end human subjects were trained to locate 5 points within a horizontal plane at shoulder level, under guidance of an acoustic signal. Next, reaching accuracy was determined for both the trained and the untrained hands without external cues. This allowed comparison of hand positioning that could be based upon a memory trace of proprioceptive inputs (trained hand) to hand positioning that must be based upon a more abstract internal representation than proprioceptive memory (untrained hand). The effect of training on reach accuracy of the two hands and the effect of prolongation the time interval between guided and recall (unguided) trials were studied. Finally, subjects were asked to interpolate between already learned target positions, a procedure which tested their ability to utilize an abstract construct of space. The relative contribution of the elbow and shoulder joints to reaching errors was determined. This analysis served to evaluate whether representation of spatial locations was based on joint angle coordinates, or on a more abstract extracorporeal reference system. Our results indicate that a memorized sensory image of the limb, which corresponds to the hand being at the target position, is used whenever possible. An abstract representation of position is used whenever comparison of the actual sensory input to a memorized sensory trace is made impossible, costing an approximately 25% reduction in accuracy. The interpolation procedure indicates that the same abstraction is used when target positions are determined mentally, as when the untrained limb performs the task. Finally, it appears that this abstract spatial representation is based on extrapersonal coordinates rather than on joint angles. 相似文献
18.
goston Trk Andrea Kbor Gyrgy Persa Pter Galambos Pter Baranyi Valria Cspe Ferenc Honbolyg 《Psychophysiology》2017,54(9):1346-1358
The spatial location of objects is processed in egocentric and allocentric reference frames, the early temporal dynamics of which have remained relatively unexplored. Previous experiments focused on ERP components related only to egocentric navigation. Thus, we designed a virtual reality experiment to see whether allocentric reference frame‐related ERP modulations can also be registered. Participants collected reward objects at the end of the west and east alleys of a cross maze, and their ERPs to the feedback objects were measured. Participants made turn choices from either the south or the north alley randomly in each trial. In this way, we were able to discern place and response coding of object location. Behavioral results indicated a strong preference for using the allocentric reference frame and a preference for choosing the rewarded place in the next trial, suggesting that participants developed probabilistic expectations between places and rewards. We also found that the amplitude of the P1 was sensitive to the allocentric place of the reward object, independent of its value. We did not find evidence for egocentric response learning. These results show that early ERPs are sensitive to the location of objects during navigation in an allocentric reference frame. 相似文献
19.
Carrozzo M Stratta F McIntyre J Lacquaniti F 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2002,147(4):426-436
Subjects reached in three-dimensional space to a set of remembered targets whose position was varied randomly from trial
to trial, but always fell along a "virtual" line (line condition). Targets were presented briefly, one-by-one and in an empty visual field. After a short delay, subjects were required
to point to the remembered target location. Under these conditions, the target was presented in the complete absence of allocentric
visual cues as to its position in space. However, because the subjects were informed prior to the experiment that all targets
would fall on a straight line, they could conceivably imagine each point target as belonging to a single rigid object with
a particular geometry and orientation in space, although this virtual object was never explicitly shown to the subjects. We
compared the responses to repeated measurements of each target with those measured for targets presented in a directionally
neutral configuration (sphere condition), and used the variable errors to infer the putative reference frames underlying the corresponding sensorimotor
transformation. Performance in the different tasks was compared under two different lighting conditions (dim light or total
darkness) and two memory delays (0.5 or 5 s). The pattern of variable errors differed significantly between the sphere condition and the line condition. In the former case, the errors were always accounted for by egocentric reference frames. By contrast the errors
in the line condition revealed both egocentric and allocentric components, consistent with the hypothesis that target information can
be defined concurrently in both egocentric and allocentric frames of reference, resulting in two independent coexisting representations.
Electronic Publication 相似文献
20.
This review surveys the recent literature on visuo-haptic convergence in the perception of object form, with particular reference to the lateral occipital complex (LOC) and the intraparietal sulcus (IPS) and discusses how visual imagery or multisensory representations might underlie this convergence. Drawing on a recent distinction between object- and spatially-based visual imagery, we propose a putative model in which LOtv, a subregion of LOC, contains a modality-independent representation of geometric shape that can be accessed either bottom-up from direct sensory inputs or top-down from frontoparietal regions. We suggest that such access is modulated by object familiarity: spatial imagery may be more important for unfamiliar objects and involve IPS foci in facilitating somatosensory inputs to the LOC; by contrast, object imagery may be more critical for familiar objects, being reflected in prefrontal drive to the LOC. 相似文献