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支气管肺蠊缨滴虫感染1例报告及文献复习 总被引:1,自引:0,他引:1
目的分析目前支气管肺蠊缨滴虫感染的现状,进一步提高认识。方法报道1例长期随访病例的治疗情况,结合文献报道的16例,分析在治疗过程中的经验和不足。结果17例中,有12例报道用甲硝唑治疗临床观察提示有效,但有2例长期随访的病例提示甲硝唑类药物及其他抗原虫药物治疗无效。4例有支气管哮喘发作应用肾上腺皮质激素治疗能缓解症状。经支气管镜治疗可以作为辅助治疗方法。结论虽然甲硝唑治疗支气管蠊缨滴虫感染的药理作用机制不明,长期观察也有无效病例,但首次治疗仍应作为首选药物。肾上腺皮质激素能减轻变态反应,可适量使用。 相似文献
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目的 提高对支气管肺蠊缨滴虫病的认识与诊断水平.方法 分析武警部队上海总队医院呼吸内科确诊的2例支气管肺蠊缨滴虫病的临床资料,结合1993-2006年文献报道的13例共15例进行文献复习.结果 (1)2例患者中,1例表现为重症哮喘,反复夜间发作咳嗽、胸闷、气喘,肺部听诊可闻及哮鸣音,支气管镜检查提示右上叶支气管狭窄、黏膜充血水肿;1例表现为支气管扩张伴感染迁延不愈,患者反复咳嗽、咳痰伴低热,胸部X线片、CT示双肺多个叶段支气管扩张伴感染,支气管镜检查提示支气管黏膜充血水肿,管腔狭窄,支气管管腔内可见白色坏死样物.2例均经支气管镜检查采集标本检验后明确诊断.(2)文献报道的13例均经病原学检查并由寄生虫病专家鉴定,诊断依据确凿.支气管肺蠊缨滴虫病最常见的症状是发热(64.3%)和咳嗽、咳痰(71.4%),半数患者外周血嗜酸性粒细胞数增多,X线胸片及胸部CT影像以肺炎样改变多见(占摄片数83.3%),慢性患者可表现为支气管哮喘、支气管扩张、肺脓肿等.痰液和经支气管镜检查采集标本,直接涂片检查是明确病原的方法.结论 支气管肺蠊缨滴虫病为新发感染性疾病,感染人体的蠊缨滴虫的宿主、传播途径、易感人群等尚不清楚,治疗亦需进一步研究. 相似文献
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支气管肺蠊缨滴虫感染是一种新的寄生虫疾病,1993年至2008年国内共确诊48例,临床诊断和治疗有一定进展,但蠊缨滴虫感染病例的临床表现缺少特征性,蠊缨滴虫自然宿主、传播途径、流行区域及致病机制等多个方面也尚不明确,其生物学分类地位也有争议,国内还没有建立抗原抗体检测或分子生物学鉴定方法. 相似文献
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一种新发机会性感染致病病原——蠊缨滴虫 总被引:1,自引:0,他引:1
据国外文献报告,蠊缨滴虫是一种寄生于白蚁、蟑螂(包括森林树木中的蟑螂)肠道的单细胞原虫.20世纪末,国内陆续有从人呼吸道检出蠊缨滴虫的报道,近年来该类病例报道明显增多.部分免疫功能低下感染蠊缨滴虫的患者常需呼吸机辅助呼吸,常用抗生素治疗无效,及时应用甲硝唑类抗生素治疗可使肺部感染得以控制.根据现有的报道我们认为蠊缨滴虫所致呼吸道感染可能是一种新发的、人们尚未完全认识的机会性感染寄生虫病. 相似文献
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呼吸道感染患者痰内发现蠊缨滴虫1例 总被引:1,自引:0,他引:1
本文报道了呼吸道感染患者痰内检到蠊缨滴虫。患者主要临床表现为发热、喘憋和咳嗽。CT确诊为右下肺炎。用抗生素头孢哌酮2 g和左旋氧氟沙星0.2 g静脉滴注bid治疗无效,止咳化痰中药汤剂也不起作用。实验室检查,发现患者血液中嗜酸粒细胞和中性粒细胞增高,并在患者咯出的痰内检到蠊缨滴虫。停用抗生素和中药,改用甲硝唑500 mg静脉滴注bid,5 d后患者治愈。 相似文献
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肾移植术后肺部蠊缨滴虫感染--附4例报道 总被引:13,自引:0,他引:13
目的:回顾性分析4例。肾移植术后肺部蠊缨滴虫感染患者的临床表现及预后。方法:4例。肾移植术后肺部感染患者经纤维支气管镜和支气管肺泡灌洗液检查确诊蠊缨滴虫感染,分析其临床特点,影像学特征和治疗、预后。结果:(1)4例。肾移植术后肺部蠊缨滴虫感染均在术后2-3个月出现,其中2例合并其他病原体感染(细菌和巨细胞病毒)。(2)病程早期均表现为单纯发热,胸片和CT显示肺门轮廓模糊、密度增高、结构不清,部分支气管影增粗,紊乱;病程中可出现咳嗽、咯痰、胸闷、气短。(3)4例经甲硝唑治疗及撤减免疫抑制剂后4-7天3例体温降至正常,1例降至37.5℃;胸片和CT上的渗出性改变明显吸收消散;2例患者治疗后行重复支气管镜检查,肺泡灌洗液镜检可见大量死亡的蠊缨滴虫。结论:(1)肺部蠊缨滴虫感染早期表现隐匿,对于病原学诊断不明确和治疗反应不佳的术后肺部感染患者,需注意蠊缨滴虫感染的可能;(2)支气管肺泡灌洗液镜检是诊断蠊缨滴虫肺部感染的确切手段,撤减免疫抑制剂同时进行甲硝唑治疗可以迅速有效地缓解病情。 相似文献
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蠊缨滴虫(Lophomonas blattarum Stein,1860)隶属于超鞭毛纲(Hypermastigida)超鞭毛目(Hypermastigida)缨滴虫科(Lophomonadae),通常寄生于白蚁和蜚蠊的消化道内,人体感染少见。1993年国内首次报道了人体感染蠊缨滴虫的病例,后又陆续报道了60余例。报道的病例多为肺部感染,鼻窦感染极少见,现报道1例上颌窦感染病例。患者,女,54岁,汉族,河北省涿鹿县食品加工厂工人。 相似文献
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Santos SA Alberto SC Cruz E Pires E Figueira T Coimbra E Estevez J Oliveira M Novais L Deus JR 《World journal of gastroenterology : WJG》2007,13(9):1466-1470
Hepatic abscess due to perforation of the gastrointestinal tract caused by ingested foreign bodies is uncommon. Pre-operative diagnosis is difficult as patients are often unaware of the foreign body ingestion and symptoms and imagiology are usually non-specific. The authors report a case of 62-year-old woman who was admitted with fever and abdominal pain. Further investigation revealed hepatic abscess, without resolution despite antibiotic therapy. A liver abscess resulting from perforation and intra-hepatic migration of a bone coming from the pilorum was diagnosed by surgery. The literature concerning foreign body-induced perforation of the gastrointestinal tract complicated by liver abscess is reviewed. 相似文献
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上皮样血管内皮瘤是一种比较罕见的肿瘤,为血管源性,恶性程度较低或介于良恶性之间,多发生于软组织,最早报道为发生于肺的上皮样血管内皮瘤,之后有其他部位的血管内皮瘤报道。肺上皮样血管内皮瘤(pulmonaryepithelioidhemangioendothelioma,PEH)是罕见的交界性的来源于肺内血管的肿瘤。现就本院收治的1例肺上皮样血管内皮瘤,结合相关文献进行讨论。 相似文献
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阴道加德纳菌通常表现为阴道内的致病菌,在临床上常常会引起细菌性阴道炎.然而在女性阴道外发生的阴道加德纳菌感染十分罕见,国内外仅有80余例病例报道.肺部发生感染的病例则更为罕见,包括本病例在内国内外共有5篇肺部感染阴道加德纳菌的报道.由于其发病罕见,临床症状、影像学等表现难以被归纳出特异性,且该细菌检测、培养难度较大,不... 相似文献
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Canora Lebrato J Aguilar Martínez JL Soto Mas J Aranda Valle C Rico Irlés J 《Anales de medicina interna (Madrid, Spain : 1984)》1999,16(1):31-34
A patients with multiple splenic abscesses of fungal origin ist presented. It is a unusual pathology that generally, only by postmortem ist diagnosed. The etiology, clinical features, diagnostic methods and therapeutic measures are discussed, and the necessity of early and accurate diagnostic and treatment. The prognosis of the splenic abscess is still associated with a high mortality. 相似文献
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Tai HC 《The Journal of infection》2007,54(1):e51-e54
Emphysematous prostatic abscess, namely, is an inflammatory process associated with gas and abscess formation in the prostate gland. It is a rare clinical condition and a few cases have been reported in the literature. We report a case of emphysematous prostatic abscess due to Klebsiella pneumoniae in a 60-year-old man with a 5-year history of diabetes mellitus and a 6-year history of alcoholic liver cirrhosis. Computerized tomography confirmed the clinical diagnosis. We successfully treated the patient with parenteral antimicrobial agents and surgical drainage. The patient was discharged without any voiding difficulty. 相似文献
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Rahmatulla RH al-Mofleh IA al-Rashed RS al-Hedaithy MA Mayet IY 《European journal of gastroenterology & hepatology》2001,13(4):437-440
Tuberculous liver abscess is rare worldwide. We report a 45-year-old man who presented with abdominal pain, fever and weight loss. Ultrasound and computed tomography of the abdomen showed multiple cystic lesions in the liver. Ultrasound guided needle aspiration revealed yellowish brownish aspirate, which was flooded with acid-fast bacilli. The abscess was drained under ultrasound guidance. Subsequent abdominal ultrasound a few days later showed resolution of the abscess cavity. He was concomitantly started on systemic antituberculous therapy. A tuberculous liver abscess has to be thought of in the differential diagnosis of liver abscesses and to consider the role of percutaneous drainage along with systemic antituberculous chemotherapy as an alternative to surgery in the management. A greater awareness of this clinical entity is required for successful treatment. 相似文献
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