温灸结合耳穴压豆疗法治疗痔瘘术后尿潴留128例临床观察

目的:探讨温灸结合耳穴压豆法治疗痔瘘术后患者尿潴留的效果。方法:将痔瘘术后患者随机分为治疗组和对照组各128例。治疗组采用温灸结合耳穴压豆疗法,对照组应用传统方法,予按摩和热敷等方法。结果:治疗组总有效率100%;对照组总有效率76.56%;在排尿时间的比较中,治疗组明显优于对照组。结论:温灸配合耳穴压豆治疗肛肠痔瘘术后尿潴留临床疗效显著,值得临床推广。     

耳穴贴压联合艾灸治疗肛肠疾病患者术后尿潴留的效果观察

目的探讨耳穴贴压联合艾灸对肛肠疾病术后尿潴留的控制效果。方法将我院收治的120例发生肛肠手术术后尿潴留的患者随机分为两组,对照组60例采用常规治疗,观察组60例在此基础上采用耳穴贴压联合艾灸的方法。比较两组患者排尿情况。结果观察组总有效率为100%高于对照组的81.7%,比较差异具有统计学意义(P<0.05)。结论对肛肠术后发生尿潴留的患者采用耳穴贴压联合艾灸治疗,效果显著,操作简捷,患者易于接受,值得推广。     

耳穴压豆法联合中药治疗甲状腺功能亢进症的临床观察

目的:观察耳穴压豆法联合中药治疗甲状腺功能亢进症的临床疗效。方法 :选取60例甲状腺功能亢进症患者,随机分为对照组和治疗组各30例。治疗组采用耳穴压豆法联合中药治疗,对照组给予单纯西药治疗。观察两组临床疗效及治疗前后甲状腺功能的变化。结果:治疗组总有效率86.67%,显著高于对照组的66.67%(P0.05);两组甲状腺功能在治疗后均有改善,治疗组优于对照组(P0.05)。结论:耳穴压豆法联合中药治疗甲状腺功能亢进症疗效显著。     

耳穴压豆配合中药足浴治疗2型糖尿病失眠症的效果观察

目的：观察耳穴压豆联合中药足浴治疗失眠的效果。方法：将60例2型糖尿病失眠症患者分为对照组和观察组各30例,观察组采用耳穴压豆加中药汤剂每晚足浴,对照组单纯采用中药汤剂每晚足浴,观察比较两组治疗10d后的效果。结果：观察组疗效总有效率为83．3％,对照组的总有效率为56．7％。两组疗效比较差异有统计学意义。结论：中药足浴联合耳穴压豆能有效改善2型糖尿病失眠症。     

针灸综合疗法预防肛肠病术后尿潴留临床观察

目的:观察运用针灸综合疗法预防肛肠病术后尿潴留的疗效.方法:将400例肛肠病手术后患者分为治疗组和对照组,各200例,治疗组采用针刺、盒灸和耳压治疗方法,对照组不采用任何针灸和药物治疗,比较两组的疗效.结果:治疗组发生尿潴留15例,发生率为7.5％;对照组发生尿潴留30例,发生率为15％.两组综合疗效比较差异显著.结论:治疗组预防肛肠病术后尿潴留有着显著疗效.     

针刺阿是穴结合耳穴压豆治疗肩周炎疗效观察

目的:观察针刺阿是穴配合耳穴压豆治疗肩周炎的临床疗效。方法:将60例肩周炎患者随机分成对照组和治疗组,每组30例。对照组采用常规针刺治疗,治疗组采用针刺阿是穴配合耳穴压豆治疗,观察两组临床疗效和治疗前后肩关节疼痛评分变化。结果:经治疗后对照组总有效率为76.7%,治疗组总有效率为93.3%,两组总有效率比较,差异有统计学意义(P0.05);治疗后两组肩关节疼痛评分均较治疗前明显降低(P0.05),且治疗组能更有效地改善肩周炎患者肩关节疼痛(P0.05)。结论:针刺阿是穴结合耳穴压豆治疗肩周炎的疗效较常规针刺疗效优。     

耳穴埋豆对贲门癌术后化疗所致呕吐的疗效观察及护理

目的:观察耳穴压豆对贲门癌术后化疗药物所致呕吐的疗效及护理方法。方法:将48例贲门癌术后进行化疗的患者随机分为治疗组与对照组,并观察呕吐症状,2组患者在化疗前均给予阿扎司琼,治疗组在化疗前30分钟进行穴位压豆。结果:治疗组比对照组效果好,有效率为92.8%,两组比较,差异有统计学意义(P0.01)。结论:耳穴埋豆法对贲门癌术后化疗所致呕吐有良好疗效。     

耳穴压豆预防肛肠科术后尿潴留100例疗效观察

目的:观察耳穴压豆在预防肛肠科术后尿潴留上的临床效果.方法:选取肛肠科疾病手术患者100例,随机分成两组,观察组术前行耳穴压豆疗法,对照组则无,观察两组术后排尿情况.结果:观察组有效44例,无效6例,有效率为88％.对照组有效11例,无效39例,有效率为22％.两组比较差异有显著性.结论:耳穴压豆对于预防肛肠科尿潴留时间较短,膀胱充盈不严重的患者有显著的效果.     

耳穴贴压配合足三里穴位注射新斯的明治疗产后尿潴留的疗效观察及护理体会

【目的】探讨耳穴贴压配合双侧足三里穴位注射新斯的明治疗产后尿潴留的临床疗效及护理体会。【方法】将60例产后尿潴留患者随机分为治疗组和对照组各30例。对照组在传统诱导排尿基础上给予新斯的明0.5 mg双侧足三里穴位注射,治疗组在对照组基础上给予王不留行籽耳穴贴压刺激相应穴位。比较2组患者尿潴留的改善情况。【结果】治疗组治疗尿潴留的总有效率为76.67%,对照组为46.67%,治疗组疗效显著优于对照组,2组比较差异有统计学意义(P0.05)。【结论】耳穴贴压配合足三里穴位注射新斯的明治疗产后尿潴留的疗效确切,能有效缩短患者自解小便的时间,减轻患者痛苦,其操作简便,便于临床应用。     

Ear Acupoint Press Therapy with Cowherb Seed in Treating 50 Cases of Urinary Retention after Renal Puncturing

目的 观察耳穴贴压防治肾穿刺术后尿潴留的疗效. 方法 选择100例行肾穿刺术后的患者,随机分为治疗组和对照组各50例,对照组采用常规护理,治疗组在常规护理的基础上行耳穴压豆法,比较2组术后尿潴留的发生率. 结果 治疗组首次排尿时间短于对照组,差异具有统计学意义(P＜0.01). 结论 耳穴压豆法可促进肾穿术后患者排尿,预防肾穿术后尿潴留的发生.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.