哮喘患者述情障碍及人格特征相关分析

目的:探讨哮喘患者的述情障碍及其与个性的相关性.方法:采用多伦多述情障碍量表(TAS)、艾森克人格问卷简式量表中国版(EPQ-RSC)对52例哮喘患者进行测查.结果:与常模比较,哮喘患者存有明显的述情障碍.哮喘患者的TAS总分、Ⅰ、Ⅱ、Ⅲ及Ⅳ因子与EPQ-RSC的个性维度E、Ⅲ因子与个性维度N呈显著负相关;TAS总分、Ⅰ、Ⅱ因子与个性维度N、Ⅱ和Ⅳ因子与个性维度P均呈显著正相关.结论:哮喘患者普遍存在述情障碍,且与个性特征有密切关系.     

哮喘患者述情障碍及人格特征相关分析

目的:探讨哮喘患者的述情障碍及其与个性的相关性。方法:采用多伦多述情障碍量表(TAS)、艾森克人格问卷简式量表中国版(EPQ-RSC)对52例哮喘患者进行测查。结果:与常模比较,哮喘患者存有明显的述情障碍。哮喘患者的TAS总分、Ⅰ、Ⅱ、Ⅲ及Ⅳ因子与EPQ-RSC的个性维度E、Ⅲ因子与个性维度N呈显著负相关;TAS总分、Ⅰ、Ⅱ因子与个性维度N、Ⅱ和Ⅳ因子与个性维度P均呈显著正相关。结论:哮喘患者普遍存在述情障碍,且与个性特征有密切关系。     

躯体化障碍患者述情障碍与心理状况、人格特征的相关研究

目的 探讨躯体化障碍患者的述情障碍与心理状况、人格特征的关系,为其心理治疗提供理论依据.方法 72例躯体化障碍患者和50名正常对照者进行多伦多述情障碍量表(TAS-20)、症状自评量表(SCL-90)及艾森克人格量表(EPQ)测定,并将结果进行分析.结果 ①躯体化障碍组的TAS总分、F1因子分、F2因子分、F3因子分均高于正常对照组,差异均有显著性(P＜0.01或P＜0.05);②躯体化障碍患者TAS与SCL-90的相关分析:TAS总分以及各因子分均与SCL-90总分、躯体化因子分呈正相关,与焦虑因子分呈负相关(P ＜0.05或P＜0.01);③躯体化障碍组TAS与EPQ的相关分析:躯体化障碍患者的EPQ-E与TAS的F2因子呈负相关,与F3因子分呈正相关;EPQ-N分与TAS的F1、F2因子分呈正相关(P＜0.05或P＜0.01).结论 躯体化障碍患者存在明显的述情障碍,且与患者的心理症状及人格存在一定互动的关系,这为躯体化障碍患者心理干预提供了思路.     

心身疾病与神经症患者的述情障碍研究

目的 :探讨心身疾病与神经症患者的述情障碍情况。方法 :以多伦多述情障碍量表 (TAS)对 30例心身疾病、31例神经症患者进行测评 ,并与正常人作对照。结果 :心身疾病、神经症患者 TAS总分分别为 (74.10± 7.86 )分、(73.2 2± 9.98)分 ,明显高于对照组 (6 6 .0 6± 6 .38)分。因子分中的 、 、 因子为显著。结论 :述情障碍常见于心身疾病及神经症患者 ,临床医师应予以重视。     

创伤后应激障碍军人述情障碍特征及其影响因素

目的探讨军人创伤后应激障碍患者的述情障碍特征及影响因素。方法采用多伦多述情障碍量表(TAS)、艾森克成人个性问卷(EPQ)、症状自评量表(SCL-90)调查了96例军人创伤后应激障碍患者(研究组),同期抽取某部100名官兵(对照组)进行测定,并将2组结果进行比较。结果军人创伤后应激障碍患者TAS总分和因子Ⅰ、Ⅱ、Ⅲ得分均显著高于对照组,而因子Ⅳ评分则低于对照组(P<0.01)。相关分析发现,研究组个性特征与述情障碍存在显著相关性(P<0.05或P<0.01);研究组SCL-90总分及各因子与TAS总分、TAS-Ⅰ、TAS-Ⅱ及TAS-Ⅲ呈显著正相关(P<0.05或P<0.01),躯体化、人际关系及焦虑与TAS-Ⅳ呈负相关(P<0.05)。结论创伤后应激障碍患者存在严重述情障碍,且与个性特征及心理健康状况密切相关。     

高中生述情障碍与心理健康的关系研究

目的：探讨高中生述情障碍与心理健康的关系。方法：采用多伦多述情障碍量表(TAS)及症状自评量表(SCL—90)对177名高中生述情障碍和心理健康状况进行测查分析。结果：TAS总分及Ⅰ、Ⅱ、Ⅲ因子均分分别与SCL—90总分及其10个因子均分存有显相关(P＜0．05或P＜0．01)，但与阳性项目数无相关关系(P＞0．05)。结论：高中生述情障碍与心理健康密切相关，心理健康水平在一定程度上取决于述情障碍的水平，述情障碍可能是影响心理健康的个性基础。     

胃十二指肠溃疡儿童个性特征的比较研究

目的　比较研究学龄儿童胃十二指肠溃疡、胃十二指肠炎和浅表性胃炎的个性特征。方法　通过内窥镜检查确诊的 4 3例胃十二指肠溃疡、12 7例胃十二指肠炎、10 1例浅表性胃炎的学龄儿童 ,平均年龄 10 .2 4岁 ;男女之比 1.3:1;与 10 0例健康学龄儿童作对照。使用儿童艾森克个性测试问卷进行个性测试 ,使用卡方检验法作统计学比较。结果　 (1)胃十二指肠溃疡组儿童 ,P维度值≤ 4 0的人数明显多于健康对照组 (P <0 .0 1)和多于胃十二指肠炎组 (P <0 .0 5 ) ;胃十二指肠炎症组和浅表性胃炎组 ,P维度值≤ 4 0的人数也多于健康对照组 (P <0 .0 5 ) ;(2 )健康对照组儿童 ,E维度值≥ 6 0的人数明显多于胃十二指肠溃疡组、炎症组和浅表性胃炎组儿童 (P <0 .0 1) ;(3)胃十二指肠溃疡组儿童 ,HP(+)人数明显多于胃十二指肠炎组和浅表性胃炎组儿童 (P <0 .0 1) ,而胃十二指肠炎组HP(+)人数也多于浅表性胃炎组儿童 (P <0 .0 5 )。结论　胃十二指肠溃疡儿童相对有如下个性特征 :个性软弱、缺乏主见、依赖性强、友善、服从、富于同情心 ,易融化于外界环境。     

十二指肠溃疡与胃溃疡患者述情障碍差异性的研究

目的探讨十二指肠溃疡与胃溃疡患者述情情况的差异性。方法使用多伦多述情障碍量表（TAS-20）,分别对十二指肠溃疡与胃溃疡患者述情情况进行测试,并比较其结果。结果十二指肠溃疡患者TAS量表的总分和因子1、因子3得分与胃溃疡患者有显著性差异。结论十二指肠溃疡患者述情障碍较胃溃疡患者明显。     

哮喘患者述情障碍及相关影响因素的研究

目的 探讨哮喘患者述情障碍及其相关因素.方法 采用多伦多述情障碍量表(TAS-26) , 艾森克人格问卷简式量表中国版(EPQ-RSC)、简明心境问卷-简式(POMS-SF)对52例哮喘患者进行了测查.结果 与常模比较,哮喘患者存有明显的述情障碍(t=2.15～5.29,P＜0.05～0.01).哮喘患者的TAS总分、Ⅰ、Ⅱ、Ⅲ及Ⅳ因子与E呈显著负相关(r=-0.372～-0.451,P＜0.01);Ⅲ因子与N呈显著负相关(r=-0.37,P＜0.01);TAS总分、Ⅰ、Ⅱ因子与N呈显著正相关(r=0.312～0.415,P＜0.01);Ⅱ和Ⅳ因子与P呈显著正相关(r=0.531～0.621,P＜0.01).TAS总分、I、Ⅱ及Ⅳ因子与POMS总分、TA、DD、AH、FI、及CB因子呈显著正相关(r=0.449～0.779,P＜0.01),TAS总分、I及Ⅱ因子与VA因子呈负相关(r=-0.418～-0.544,P＜0.05～0.01),Ⅳ因子与VA因子呈负相关(r=-0.320,P＜0.05).结论 哮喘患者普遍存在述情障碍, 且与个性特征及心境状况密切相关.     

精神分裂症患者述情障碍与自测健康状况及抑郁的关系

目的 了解住院精神分裂症患者述情障碍与自测健康状况及抑郁情绪的关系.方法 采用自拟一般情况问卷、多伦多述情量表(TAS)、自测健康状况评定量表(SRHMS)、自评抑郁量表(SDS)对320例住院的精神分裂症患者与120名健康志愿者(对照组)进行评定,并进行相关与回归分析.结果 (1)除TAS因子II,精神分裂症组TAS总分及各因子分均显著高于对照组[依次为(73.53±10.38)分、(68.56±8.24)分;(17.61±4.67)分,(17.01±2.17)分;(15.25±4.33)分、(13.47±4.01)分;(19.65±4.40)分,(18.15±3.55)分;P <0.05或P <0.01)].(2)精神分裂症患者TAS的多个维度与SRHMS、SDS的多个纬度呈显著相关( r =0.113～0.400,P <0.05或P <0.01).(3)SDS的躯体障碍因子、受教育年限、SRHMS的心理症状与负向情绪因子等依次进入精神分裂症TAS总分的回归方程.结论 住院精神分裂症存在明显的述情障碍,躯体障碍、受教育年限、健康状况等是其述情障碍严重程度的重要影响因素.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Electro-Acupuncture Combined with the Trigger Point Needle-Embedding for Treatment of Primary Trigeminal Neuralgia in 31 Cases

In recent years, the author of this essay has applied electro-acupuncture combined with the trigger point needle-embedding for treatment of primary trigeminal neuralgia in 31 cases, yielding satis- factory results as reported in the following.     

Investigation of Matrix Metalloproteinase -1, 2 and tissue inhibitor of matrix metalloproteinases-1 in Endometriosis

Objective： To explore the role of matrix metalloproteinase-1,2 （MMP-1, MMP-2） and tissue inhibitor of matrix metalloproteinases-1 （TIMP-1） in endometriosis. Methods： The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.endometria from 40 subjects （excluding endometriosis） were collected and examined by in situ hybridization technology and western blot assay. Results： Both expressions of MMP-1 and -2 were stronger in ectopic endometrium and eutopic endometrium than in normal endometrium. On the contrary, the expression of TIMP-1 in ectopic endometrium and eutopic endometrium was lower. The differences were significant （P 〈 0.01 ）. Moreover, there was no relationship among the expressions of MMP-1, 2 and TIMP-1 in ectopic endometrium. Conclusion： The expressions of MMP-1, 2 and TIMP-1 lose balance and lack of periodic changes in ectopic endometrium , which explains the biological invasive behavior of endometriosis. It was suggested-that regulating the balance between the MMPs and TIMP-1 should be an ideal therapeutic target to endometriosis.     

Shi Da-zhuo (史大卓) —An outstanding cardiologist of integrative medicine

Prof. SHI Da-zhuo, Ph.D., male, was born on March 20, 1960. Prof. SHI entered the Ph.D. program in 1990 at the China Academy of Chinese Medical Sciences under the supervision of Prof. CHEN Ke-ji, majoring in the treatment of cardiovascular diseases. After receiving his Ph.D. degree in 1993, Prof. SHI started working at the Cardiovascular Center in Xiyuan Hospital affiliated to China Academy of Chinese Medical sciences.     

Persist in and Carry Forward the Integrative Medical Research——Speech at the 6th National General Congress of Chinese Association of Integrative Medicine by Academician CHEN Zhu,Minister of Ministry of Health

The 6th National General Congress of Chinese Association of Integrative Medicine （CALM） was convened at 19-20, April 2008 in Beijing. Academician CHEN Zhu, the minister of Ministry of Health indicated at the congress that the integration of Chinese and Western medicine is very well in keeping with the situation of our country and the general rule of development in medical science; and as a good integration of Chinese medicine and Western medicine, it is mutually beneficial and advantageous to both of them. Seeing the creativity shown in integrative medical investigation in theoretic and methodological sides, we should and must persist in and develop it.