军队老干部胸痛患者的心理状态调查

目的：观察军队老干部胸痛患者的心理状态并探讨其临床意义。方法：采用横断面研究整群抽样法,对在我院接受冠状动脉造影术（CAG）检查的军队老干部胸痛59例,术前使用汉密尔顿焦虑量表（HAMA）、汉密尔顿抑郁量表一17项（HAMD-17）进行心理状态评估,观察其术前焦虑、抑郁等情绪改变;同时结合CAG检查结果,比较CAG阳性与阴性者的评分差异。结果：术前有焦虑症状26例（44．1％）,有抑郁症状10例（16．9％）,既有焦虑又有抑郁8例（14．2%）;CAG检查阳性43例,其焦虑症状较阴性者更为显著。结论：军队老干部胸痛患者焦虑及抑郁症状发生率较高,应及时进行干预治疗。     

平板运动试验阳性而冠脉造影阴性患者100例临床分析

目的:通过分析平板运动试验(TET)阳性而冠脉造影(CAG)阴性患者的临床特征,增强对TET阳性及其临床意义的认识,提高冠心病(CAD)的诊断准确率。方法:对我院近3年因胸痛住院患者进行TET检查,结果TET阳性而CAG阴性的100例患者临床特征进行回顾性分析。结果:TET阳性而CAG阴性的患者以女性多于男性;其中心脏自主神经功能紊乱占50%,高血压、肥厚型心肌病占28%,微血管性心绞痛(X综合症)占11%,冠状动脉肌桥占8%,先天性冠状动脉瘘占3%。结论:TET阳性且有典型心绞痛症状,但冠脉造影阴性的高血压患者,其发病机制应考虑为冠脉微血管病变所致;而心绞痛症状不典型者、或仅以ST-T改变的女性患者,若不伴或极少伴有CAD危险因素,临床诊断CAD更应慎重。     

烧伤患者抑郁症状的危险因素分析

【摘要】目的 探索烧伤患者抑郁症状的相关危险因素。方法 选取2019年4月至2020年1月安徽医科大学第一附属医院收治的206例烧伤患者作为研究对象,收集患者性别、年龄、婚姻状况、文化程度、体重指数、烧伤严重程度、烧伤面积以及汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、急性应激障碍量表(ASDS)、失眠严重程度指数量表(ISI)评分,Logistic回归分析烧伤患者伴发抑郁症状的危险因素,Spearman相关性分析各因素与烧伤患者伴发抑郁症状的相关性。结果 206例烧伤患者共收集有效问卷194份(94.17%),194例患者中伴发抑郁症状者111例(57.22%),设为抑郁组;未伴发抑郁症状者83例(42.78%),设为非抑郁组。Logistic回归分析结果显示,HAMA、ASDS高评分是烧伤患者伴发抑郁症状的独立危险因素(95%CI为1.170～1.573、1.000～1.080,P＜0.001、P=0.049);Spearman相关性分析结果显示,烧伤面积、HAMA评分、ASDS评分、ISI评分与烧伤患者伴发抑郁症状呈显著正相关性(r=0.269、0.765、0.618?0.517,P均＜0.001)。结论 HAMA、ASDS高评分是烧伤患者伴发抑郁症状的独立危险因素。     

常规加劳拉西泮治疗冠心病合并焦虑抑郁疗效观察

目的：观察常规加劳拉西泮治疗冠心病合并焦虑抑郁的疗效。方法：选择冠心病合并焦虑抑郁60例,随机分为常规治疗组（对照组）和常规加劳拉西泮组（观察组）各30例,分别采用汉密尔顿焦虑量表（HAMA）在治疗前后进行评测,观察冠心病及焦虑抑郁状态缓解情况。结果：观察组治疗后HAMA评分较对照组显著下降,心绞痛发作次数减少,焦虑抑郁症状减轻。结论：常规加劳拉西泮治疗冠心病合并焦虑抑郁安全有效,效果更好。     

128层螺旋CT冠状动脉成像对冠心病诊断的临床价值

目的:探讨128层螺旋CT冠状动脉成像(128-SCTCA)在冠心病中的临床应用价值。方法:对349例疑似冠心病患者行128-SCTCA筛查,对其中59例患者同时作选择性冠状动脉血管造影(CAG)检查,分析比较128-SCTCA诊断冠心病的敏感性、特异性、阳性预测值、阴性预测值和准确率。结果:341例患者成功完成了128-SCTCA检查,并可清晰显示冠脉主干及其主要分支,193例患者的596支冠脉伴有不同性质的斑块和不同程度的狭窄,对其中59例冠心病患者以CAG为金标准,得出128-SCTCA诊断冠脉狭窄的敏感性、特异性、阳性预测值、阴性预测值及准确率分别为100%、90.23%、92.57%、100%、95.59%。从59例患者的295支冠脉中检测出136个斑块,脂质软斑块、纤维斑块及钙化硬斑块分别占18%、11%、71%。结论:128层CT冠脉成像是一种无创的成像方法,检出冠心病的准确程度高,对冠状动脉狭窄的诊断准确率接近CAG,区分高危斑块优于CAG,作为冠心病的一种无创筛查手段具有很高的临床应用价值。     

心绞痛患者冠脉造影与TET结果对比研究

目的:以冠状动脉造影为依据与心电图运动试验(TET)比较,探讨TET的假阳性因素。方法:对270例胸痛患者进行TET和冠状动脉造影(CAG)检查,收集病史及辅助检查资料。对比TET和CAG的结果,计算TET的敏感性、特异性和准确性;对比TET真阳性组和假阳性组的各项临床资料特点并进行统计学分析。结果:本组病例TET诊断冠心病的敏感性为76.3%,特异性为65.5%,准确性为69.6%;假阳性组女性患者例数较多;具有典型胸痛症状、高脂血症、吸烟史、饮酒史、冠心病家族史的例数较少;运动中ST段的下降多发生于Ⅱ、Ⅲ、aVF导联,ST段下降>0.2mV以及运动中出现心绞痛的例数较少,两组差别有统计学意义。结论:性别、典型缺血性胸痛症状、冠心病的某些危险因素、运动后心电图发生变化的部位和程度、运动中胸痛症状的出现,是造成TET假阳性结果的误诊因素。     

心理干预对数字减影脑血管造影术患者的影响

目的 探讨数字减影脑血管造影术对患者情绪的影响及心理干预的作用.方法 采用社会心理因素调查表对81例行数字减影脑血管造影术的患者进行调查,并用汉密尔顿焦虑量表 (HAMA)、汉密尔顿抑郁量表(HAMD)、焦虑自评量表(SAS)和抑郁自评量表(SDS)比较心理干预前后患者的焦虑、抑郁情况及不同疾病患者的焦虑、抑郁情况.结果 患者主要由于对诊疗方法不了解及担心手术失败而造成心理压力;心理干预后患者的焦虑、抑郁情况得到改善 (P<0.01) ;不同疾病患者术前的焦虑情况有显著差别(P<0.05),心理干预后差异消失.结论 心理干预可有效缓解行数字减影脑血管造影术患者的焦虑、抑郁情绪,应作为数字减影脑血管造影术的辅助治疗措施.     

冠状动脉病变程度与抑郁障碍相关性研究

目的探讨胸痛患者冠状动脉病变程度与抑郁障碍的关系。方法选取2014年10月至2015年6月收治的717例胸痛患者,行冠状动脉造影术前采用综合医院抑郁量表(HADS-D)进行测评,统计抑郁症的发病率。同时,结合Gensini评分标准对患者冠状动脉病变进行分级,分析冠状动脉病变程度与HADS-D评分的关系。结果本组717例患者中,235例患抑郁症,发病率为32.78%。冠状动脉正常者及冠心病患者抑郁症发病率分别为40.83%(49/120)和31.16%(186/597),差异有统计学意义(P<0.05)。冠状动脉正常者及冠状动脉重度狭窄患者抑郁评分分别为(6.38±3.80)分和(6.82±3.93)分,较其他程度冠状动脉病变患者高。不同程度冠状动脉病变患者抑郁症发病率比较,差异有统计学意义(P<0.05)。结论冠状动脉正常及冠状动脉重度狭窄者更易出现抑郁障碍,抑郁障碍程度与冠状动脉病变程度无相关。     

拟诊冠心病患者心电图与冠状动脉造影结果分析

 目的通过对178例拟诊冠心病患者的静息心电图(ECG)与冠状动脉造影结果进行回顾性分析,评价静息心电图(ECG)对冠心病诊断和预后的价值.方法选择有冠心病典型症状及危险因素的患者,男109例、女69例,年龄62.5(61.5±11.1)岁.其中,99例患者ECG有心肌缺血表现(ECG阳性组),79例无心肌缺血表现(ECG阴性组).对所有拟诊患者进行冠状动脉造影(CAG)检查.结果静息ECG阳性与阴性组患者,CAG阳性率无显著性差异(54.5%vs 59.5%,P＞0.05);静息ECG对冠心病诊断的敏感性为56.4%,特异性为36.8%;静息ECG阳性组多支病变率明显高于ECG阴性组(66.7%vs 44.7%,P=0.029);静息ECG阴性组单支病变率明显高于ECG阳性组(55.3%vs 33.3%,P=0.026).静息ECG阳性组高血压患病率明显高于ECG阴性组(P=0.042).结论静息ECG阳性对诊断冠心病的特异性和敏感性低,对多支、多危险因素的高危冠心病患者具有一定的提示意义.     

冠状动脉CT血管成像和运动平板试验对冠心病患者的诊断比较

目的:评价冠状动脉CT血管成像(CCTA)和运动平板试验(TET)对冠心病的诊断价值。方法:以常规冠状动脉造影(CAG)为诊断冠心病(冠脉狭窄≥50%)的"金标准",对同期先后行TET、CCTA和CAG 3种检查的75例疑似冠心病患者进行回顾性分析,将其TET和CCTA的结果与CAG进行比较。结果:TET和CCTA诊断冠心病的敏感度分别为45.2%和90.5%,特异度为69.7%和93.9%,阳性预测值为65.5%和95.0%,阴性预测值为50.0%和88.6%,准确率为56.0%和92.0%,P<0.01。在冠状动脉血管水平CCTA对右冠状动脉、左主干、前降支、回旋支狭窄诊断的准确率分别为86.7%、100.0%、88.0%和76.0%。冠心病患者中TET诊断阳性率与病变血管支数呈正相关(r=0.440,P=0.004);冠心病患者TET诊断结果阳性与阴性仅与血管狭窄程度≥75%狭窄的节段数目有统计学差异(P=0.016)。结论:CCTA诊断冠心病较TET有更高的诊断准确性和较低的诊断假阳性和假阴性,对有症状的疑诊冠心病患者CCTA的诊断具有更重要作用。     

Relationship between silent myocardial ischemia and coronary artery disease risk factors

Background

The association between silent myocardial ischemia (SMI) and coronary artery disease (CAD) risk factors in asymptomatic patients with no prior history of CAD referred for stress myocardial perfusion imaging (MPI) is unknown.

Methods

We retrospectively evaluated patients who underwent MPI over a 3.4-year period to identify those who did not have chest pain, dyspnea, or known CAD. The presence of risk factors was categorized as none, 1-2, 3-4, and ≥5. MPI was performed using a rest thallium-201/stress Tc-99m sestamibi protocol, and read using a standard five-point perfusion score (0 = normal to 4 = absent) and a 17-segment left ventricular model. Summed stress score and summed rest score were derived as the sum of individual segmental scores at stress and rest, respectively. SMI was diagnosed if the summed differences score (SDS) was ≥2. Prognostically significant ischemia was defined by a SDS ≥ 8.

Results

Among 1,354 asymptomatic patients, SMI was present in 97 (7.2%) and prognostically significant in 60 (4.4%). The prevalence, but not severity, of SMI increased with increasing CAD risk factors—0 for none, 4.1% for 1-2, 8.8% for 3-4, and 12% for those with ≥5 CAD risk factors (P value for trend = .001), in patients <74 years of age. Of the 59 (4.4%) patients who underwent coronary angiography, only 31 (2%) had significant anatomical CAD.

Conclusions

The prevalence of SMI and prognostically significant ischemia is low in asymptomatic patients without known CAD, and is related to the number of CAD risk factors in patients younger than 74 years of age.     

平板运动试验及心肌灌注显像在飞行人员不典型心肌缺血诊断中的对比研究

目的评价活动平板运动试验对飞行人员不典型心肌缺血的诊断价值，并和心肌灌注显像及冠状动脉造影作对比研究，为其医学鉴定提供参考依据。方法不典型胸痛患者38例，均行活动平板运动试验及心肌灌注显像，结果分别与冠状动脉造影相比较。结果38例冠状动脉造影检查中有13例冠状动脉狭窄病变；运动试验阳性15例，阴性23例；心肌灌注显像检出可逆性心肌缺血16例，阴性22例。运动试验、心肌灌注显像诊断冠心病心肌缺血的灵敏度、特异性、准确性分别为53．8％、68．0％、63．2％和92．3％、84．0％、86．8％。结论活动平板运动试验出现异常ST—T改变，对诊断不典型胸痛患者冠心病心肌缺血有一定的意义，对飞行人员群体的冠心病诊断和排除亦有一定的应用价值。心肌灌注显像在飞行人员体检中的应用价值高于平板运动试验。     

急性心肌梗死80岁以上高龄患者急诊介入的临床效果

探讨80岁以上的高龄的急性心肌梗死（AMI）患者急诊介入治疗（PCI）的疗效及安全性。方法：对24例平均年龄（84．0±3．7）岁的急性心梗患者进行PCI,观察手术即刻效果及近远期疗效。结果：22例取得即刻成功（成功率91．7％）,共对32支靶病变血管行PCI,共植入支架41（平均1．7±0．8）枚。15支IRA为完全闭塞病变,即刻开通14支,院内死亡4例。平均随访（18．5±14．8）月,14例未再出现心绞痛,1例术后8月死：亍二肺癌。结论：急诊PCI对80岁以上的高龄AMI患者来说,仍是一种安全、有效的治疗手段。     

Coronary calcium score and computed tomography coronary angiography in high-risk asymptomatic subjects: assessment of diagnostic accuracy and prevalence of non-obstructive coronary artery disease

Objectives

The aim of the study was to compare the coronary artery calcium score (CACS) and computed tomography coronary angiography (CTCA) for the assessment of non-obstructive/obstructive coronary artery disease (CAD) in high-risk asymptomatic subjects.

Methods

Two hundred and thirteen consecutive asymptomatic subjects (113 male; mean age 53.6?±?12.4 years) with more than one risk factor and an inconclusive or unfeasible non-invasive stress test result underwent CACS and CTCA in an outpatient setting. All patients underwent conventional coronary angiography (CAG). Data from CACS (threshold for positive image: Agatston score 1/100/1,000) and CTCA were compared with CAG regarding the degree of CAD (non-obstructive/obstructive; </≥50% lumen reduction).

Results

The mean calcium score was 151?±?403 and the prevalence of obstructive CAD was 17% (8% one-vessel and 10% two-vessel disease). Per-patient sensitivity, specificity, positive and negative predictive values of CACS were: 97%, 75%, 45%, and 100%, respectively (Agatston?≥1); 73%, 90%, 60%, and 94%, respectively (Agatston?≥100); 30%, 98%, 79%, and 87%, respectively (Agatston?≥1,000). Per-patient values for CTCA were 100%, 98%, 97%, and 100%, respectively (p?<?0.05). CTCA detected 65% prevalence of all CAD (48% non-obstructive), while CACS detected 37% prevalence of all CAD (21% non-obstructive) (p?<?0.05).

Conclusion

CACS proved inadequate for the detection of obstructive and non-obstructive CAD compared with CTCA. CTCA has a high diagnostic accuracy for the detection of non-obstructive and obstructive CAD in high-risk asymptomatic patients with inconclusive or unfeasible stress test results.     

Measurement of coronary calcium scores by electron beam computed tomography or exercise testing as initial diagnostic tool in low-risk patients with suspected coronary artery disease

We determined the efficiency of a screening protocol based on coronary calcium scores (CCS) compared with exercise testing in patients with suspected coronary artery disease (CAD), a normal ECG and troponin levels. Three-hundred-and-four patients were enrolled in a screening protocol including CCS by electron beam computed tomography (Agatston score), and exercise testing. Decision-making was based on CCS. When CCS≥400, coronary angiography (CAG) was recommended. When CCS<10, patients were discharged. Exercise tests were graded as positive, negative or nondiagnostic. The combined endpoint was defined as coronary event or obstructive CAD at CAG. During 12±4 months, CCS≥400, 10–399 and <10 were found in 42, 103 and 159 patients and the combined endpoint occurred in 24 (57%), 14 (14%) and 0 patients (0%), respectively. In 22 patients (7%), myocardial perfusion scintigraphy was performed instead of exercise testing due to the inability to perform an exercise test. A positive, nondiagnostic and negative exercise test result was found in 37, 76 and 191 patients, and the combined endpoint occurred in 11 (30%), 15 (20%) and 12 patients (6%), respectively. Receiver-operator characteristics analysis showed that the area under the curve of 0.89 (95% CI: 0.85–0.93) for CCS was superior to 0.69 (95% CI: 0.61–0.78) for exercise testing (P<0.0001). In conclusion, measurement of CCS is an appropriate initial screening test in a well-defined low-risk population with suspected CAD.     

钙化积分、CTCA以及两者联合对冠状动脉狭窄的诊断价值

目的:探讨冠状动脉钙化积分(CS)、CT冠状动脉成像(CTCA)以及两者联合对诊断冠状动脉狭窄病变的价值.方法:189例患者均行冠状动脉钙化积分扫描、CT冠状动脉成像以及传统冠状动脉造影(CAG)检查.计算CS、CT-CA以及两者联合诊断冠状动脉病变的符合率,并记录有效X线剂量.结果:189例患者中临床诊断为冠心病156例(82.5％),经冠状动脉造影检测出至少有1支冠状动脉狭窄≥50％.采用钙化积分250分作为诊断阈值,检测冠状动脉狭窄≥50％的敏感度和特异度分别为42.9％(67/156)和96.9％(32/33).CTCA检测冠状动脉狭窄≥50％的敏感度和特异度分别为98.1％(153/156)和72.7％(24/33).CS和CTCA联合时,检测冠状动脉狭窄≥50％的敏感度和特异度分别为96.2％(150/156)和87.9％(29/33).结论:钙化积分对诊断冠状动脉狭窄有着很高的特异度;CTCA对诊断冠状动脉狭窄有着很高的敏感度;CTCA联合钙化积分扫描可提高冠状动脉狭窄的诊断符合率.     

核素心肌灌注显像与64层螺旋CT诊断冠状动脉疾病的对比研究

目的 对比分析心肌灌注显像（MPI）与64层螺旋CT（MSCT）对冠状动脉疾病（CAD）的诊断价值.方法 对52例可疑和确诊CAD患者（疑诊43例,确诊9例）进行MPI检查,并均在1个月内行冠状动脉造影（CAG）和64层MSCT检查.MPI结果分析采用17节段5分制,获得运动负荷显像灌注总积分和静息显像灌注总积分,两者差值大于1为心肌缺血,判断为阳性.MSCT结果主要以冠状动脉或其主要分支中至少有1支血管管腔狭窄≥50%判定为阳性.以CAG结果为诊断CAD的＂金标准＂.采用SPSS 13.0软件,用Kappa值检验2种方法结果的一致性,两样本率的比较采用配对资料x2检验.结果 MPI和MSCT诊断CAD的灵敏度、特异性、阳性预测值、阴性预测值及准确性分别为86.7%（26/30）、77.3%（17/22）、83.9%（26/31）、81.0%（17/21）、82.7%（43/52）和83.3%（25/30）、86.4%（19/22）、89.3%（25/28）、79.2%（19/24）、84.6%（44/52）;MPI和MSCT对病变血管检出的灵敏度、特异性、阳性预测值、阴性预测值及准确性分别是74.5%（38/51）、81.0%（85/105）、65.5%（38/58）、86.7%（85/98）、78.8%（123/156）和90.2%（46/51）、88.6%（93/105）、79.3%（46/58）、94.9%（93/98）、89.1%（139/156）,2种方法诊断CAD和病变血管差异均无统计学意义（x2=0.44和0.21,P均＞0.05）.MSCT评价病变血管轻度、中度和高度狭窄的灵敏度分别为76.5%（13/17）,78.3%（18/23）和89.6%（43/48）.MPI和MSCT诊断CAD的效能相近,Kappa值为0.64（＜0.75）.25例2种方法均阳性患者,96.0%（24/25）确诊为CAD;18例均阴性的患者,83.3%（15/18）可排除CAD.结论 MPI和MSCT均为筛选、诊断CAD的重要无创检查手段,但信息互补,不可替换.     

Prevalence and characteristics of coronary artery disease in a population with suspected ischaemic heart disease using CT coronary angiography: correlations with cardiovascular risk factors and clinical presentation

PURPOSE: This study was undertaken to describe the correlation between the distribution of coronary artery disease (CAD) in a symptomatic population with suspected ischaemic heart disease, cardiovascular risk factors (RF) and clinical presentation. MATERIALS AND METHODS: we studied 163 patients (mean age 65.5 years; 101 men and 62 women) referred for multidetector computed tomography coronary angiography (MDCT-CA) to rule out CAD. The patients had no prior history of revascularisation or myocardial infarction. We analysed how the characteristics of CAD (severity and type of plaque) can change with the increase in RF and how they are related to different clinical presentations. RESULTS: patients were divided into three groups according to the number of RF: zero or one, two or three, and four or more. The percentage of coronary arteries with no plaque, nonsignificant disease and significant disease was 55%, 41% and 4%, respectively, in patients with zero or one RF; 27%, 51% and 22%, respectively, in patients with two or three RF; and 19%, 38% and 44%, respectively, in patients with four or more RF. Plaque in patients with nonsignificant disease was mixed in 65%, soft in 18% and calcified in 17%. The percentage of coronaries with no plaque in the three RF groups was 50%, 20% and 0% in patients with typical chest pain and 46%, 24% and 12% in those with atypical pain. The percentage of significant disease in patients with typical pain was 0%, 47% and 86% and in those with atypical pain 4%, 20% and 29%. CONCLUSIONS: MDCT plays an important role in the identification of CAD in patients with suspected ischaemic heart disease. Severity and type of disease is highly correlated with RF number and assumes different characteristics according to clinical presentation.     

Esophageal dysfunction in patients with atypical chest pain investigated with esophageal scintigraphy and myocardial perfusion imaging: An outcome study

BACKGROUND: The objectives of this study were to determine the role of esophageal scintigraphy (ES) and myocardial perfusion imaging (MPI) in patients with atypical chest pain investigated for ischemic heart disease (IHD). METHODS AND RESULTS: One hundred five consecutive patients with atypical chest pain were investigated by dual-isotope MPI (1-day rest-stress protocol). Within a 10-day period, each patient also had liquid and semisolid ES performed with dynamic imaging over a 2-minute period for each phase. All patients were risk-stratified, and 28 patients were also investigated by coronary angiography. Patient outcome was assessed with the use of endpoints including cardiac death, myocardial infarction, and coronary revascularization procedures. Of the patients, 53 (50%) had esophageal dysfunction (ED) but no IHD, 41 (39%) had both ED and IHD, 5 (5%) had normal ES and IHD, and 6 (6%) had neither ED nor IHD. On the basis of outcome findings (n = 105) and coronary angiogram results (n = 28), MPI showed sensitivity for the detection of IHD of 92% in this patient population. Of the 94 patients (89%) with ED, 48 (51%) showed esophageal dysmotility, 9 (10%) showed gastroesophageal reflux, 17 (18%) showed esophageal spasm and dysmotility, 17 (18%) showed both reflux and dysmotility, and 3 showed other abnormalities. The median follow-up period after MPI was 20 months (range, 9-30 months). Twenty-one patients had cardiac events. These included 2 cardiac deaths, 2 myocardial infarctions, 6 coronary artery bypass graft surgeries, and 11 angioplasty/stent procedures. All but 2 of these patients had abnormal ES studies, and 7 had no prior history of IHD. MPI detected IHD in all but 2 of these patients. CONCLUSIONS: There is a high incidence of ED in patients with atypical chest pain referred for cardiologic assessment. The low proportion of patients with IHD alone and of those with neither IHD nor ED presenting with atypical chest pain (5%), as well as the high proportion with ED alone (50%), indicates the high likelihood of chest pain derived from ED. However, of the 21 patients with cardiac events, 7 had no prior history of IHD, indicating the importance of the use of MPI in the investigation of patients with atypical chest pain syndromes.     

动态容积320排冠状动脉CT血管成像诊断冠状动脉疾病的意义

目的：研究320排动态容积冠状动脉CT成像（CCTA）诊断冠状动脉疾病（CAD）的可行性。方法：5961例临床诊断CAD的患者进行CCTA检查,其中186例接受常规X线冠状动脉造影术（CAG）,对照分析其检查结果。1490例接受CCTA检查的健康查体者作为对照。结果：成像质量均在I～III级,无呼吸伪影图像。在186例CAD患者中,CCTA诊断冠状动脉狭窄（狭窄度≥50％）的敏感性为96．72％,特异性98．95％,阳性预测值95．16％,阴性预测值99．30％,准确度98．56％。结论：320排动态容积CT冠状动脉成像图像清晰,对诊断CAD具有重要的临床价值。