难治性产科出血时子宫切除术和子宫动脉栓塞术的临床分析

目的探讨产科急性出血性疾病治疗过程中进行子宫切除术和动脉栓塞术的临床特点以及选择时机。方法回顾性分析35例产科出血因素行子宫切除或者动脉栓塞病例的临床资料。结果16例子宫切除的患者中,胎盘因素10例,占62.5%（前置胎盘/胎盘植入7例,胎盘早剥伴有凝血功能障碍3例）,子宫异常4例（子宫收缩乏力2例、子宫切口延裂致阔韧带血肿和子宫破裂各1例）占25%;羊水栓塞致DIC后切除子宫2例占12.5%。19例行子宫动脉栓塞术中,前置胎盘3例,占15.8%,子宫收缩异常13例（原发性宫缩乏力产程中剖宫产4例、双胎4例,急产产后出血2例,巨大儿1例,巨大子宫肌瘤2例）占68.4%,剖宫产并发症3例（子宫切口延裂致阔韧带血肿和子宫动脉瘤各1例,剖宫产术后晚期产后出血1例）占15.8%,其中2例栓塞失败,分别行子宫切除术和开腹探查血肿清除术。子宫切除术平均出血量（4 593±2 727）ml,子宫动脉栓塞术时平均出血量（2 601±904）ml,两组比较差异有统计学意义（P〈0.05）。子宫切除组有11例出现了DIC表现占68.7%。行子宫动脉栓塞术时发生DIC1例,占10.5%,差异有统计学意义（P〈0.05）。结论二者均为治疗产后出血的有效手段,但是栓塞术作为保守治疗可以保留生育功能,对于改善患者的预后具有重要的意义,要求尽早采用,一旦发生了严重的DIC和休克,则失去了机会。而保守治疗不能短时间见效,应果断行子宫切除术。     

Vaginal birth of twins after a previous Cesarean section

OBJECTIVE: To determine whether a vaginal birth of twins after a Cesarean section carried greater risk than for a singleton gestation as well as determining whether there was a similar likelihood of successful vaginal birth. METHODS: A retrospective study was carried out of all twin pregnancies in which vaginal birth was attempted after a Cesarean section, in 1991-99. The next three consecutive singleton pregnancies in which vaginal birth was attempted after a Cesarean section were also evaluated. Comparisons were made for successful vaginal birth after Cesarean section complications (blood loss, uterine rupture or dehiscence, hysterectomy, chorioamnionitis and neonatal morbidity). Where appropriate, X2 tests of association or Student's t tests were used. Significance was set at p < 0.05. RESULTS: A total of 19 twin pregnancies met the study criteria. There were 57 controls. Gestational ages differed slightly (twin pregnancies, 36.3 weeks; controls, 39.3 weeks). The success rate of vaginal birth after Cesarean section was 84.2% for twin pregnancies and 75.4% for controls. The incidence of postpartum hemorrhage was 5.3% for both groups. One uterine rupture occurred in the control group; none occurred in the twin pregnancy group. One uterine dehiscence occurred in each group. No significant differences were found for any of the other parameters tested. CONCLUSION: The option of vaginal birth of twins after Cesarean section appears to have a similar risk and shares a similar likelihood of success to those of a singleton pregnancy. In view of the lack of increased complications, this option can be offered to patients with twin pregnancies who are eligible for vaginal birth after Cesarean section.     

Incidence and indications for cesarean section in the Obstetrics Clinic in the University Hospital of Obstetrics and Gynecology "Maichin Dom" in Sofia

The incidence and the indications for Cesarean section in the Obstetric Clinic of the University Hospital of Obstetrics and Gynecology were analysed and compared to a study carried out 20 years ago In 2003 - 2004 there were 2700 pregnant women treated in the clinic 558 had Cesarean section (incidence 20.7%). For comparison the incidence of Cesarean section in 1985 was 6.67% (160 Cesarean sections for 2096 patients) and for 1986 the incidence was 7.63% (131 Cesarean Sections for 1865 patients. The leading indication for the both studies was "previous Cesarean section" the indication "contracted pelvis" was the second and infertility and breech presentation were on the third and forth place. There was no change in the indications for Cesqarean section in the present study and the study carried out 20 years ago. There was a relative increase of the indications 'contracted pelvis' and 'increased age in a nulliparous patiet' compared to the previous years.     

The obstetrical history in patients with Pfannenstiel scar endometriomas--an analysis of 81 patients

INTRODUCTION: The participation of immune tolerance during pregnancy was suggested to be an important factor predisposing to the implantation of decidual cells after cesarean section in Pfannenstiel scar. Delivery at term is related to the termination of immune tolerance to fetal antigens that is maintained throughout pregnancy. Substantial proportion of cesarean section deliveries is performed before the onset of true term labor. The aim of this study was to analyze the clinical symptoms of spontaneous beginning of labor in pregnant women in whom cesarean sections were performed and in whom Pfannenstiel scar endometriomas were observed during follow-up. MATERIALS AND METHODS: We have retrospectively analyzed 81 patients following the surgical removal of scar endometrioma after cesarean section. Obstetrical histories of cesarean sections in the number of 5,370 preceding the occurrence of the scar endometrioma were analyzed. These data were collected in six different Gynecological and Obstetrical wards in Malopolska Province in Poland. Analysis of data was started by the retrospective evaluation of regular uterine contractions, uterine cervix ripening before cesarean section and the indications for surgery. RESULTS: In 67 women from the group of 81 patients cesarean sections were performed with unripe uterine cervix and without the presence of regular uterine contractions. Elective indications for cesarean sections were predominant in this group of women. The relative risk of scar endometriomas occurrence following cesarean sections performed before onset of labor in comparison to cesarean sections following spontaneous onset of labor was statistically significantly higher [RR = 2.16, 95% CI = 1.21-3.83; OR = 2.18, 95% CI = 1.22-3.89]. CONCLUSIONS: Cesarean section performed before spontaneous onset of labor may increase substantially the risk of occurrence of scar endometriomas.     

New trends in cesarean section

The Authors studied the frequency of Cesarean section in relation to deliveries in the last trimester of pregnancy, the frequency of repetitive Cesarean section, age and parity of the patients, indication for cesarean section, week of delivery, and perinatal and maternal morbidity and mortality at the First Clinic of Obstetrics and Gynecology, University of Catania, Catania, Italy, from 1972 to 1974 and from 1983 to 1985. The frequency of Cesarean section has increased from 12.07% (735 cases out 6,086 deliveries) to 16.89% (837 cases out of 4,955 deliveries). There was a decrease in frequency of repetitive Cesarean section from 30.47% (224 cases) to 27.95% (234 cases) and in perinatal mortality rate from 4.35% (32 cases out of 735) to 3.19% (27 cases out of 845 newborn). There were no cases of maternal death, while the most common cause of maternal morbidity was uterine atonia. From 1972 to 1974 mechanical causes were the most frequent indication for Cesarean section (28.16% -207 cases), while from 1983 to 1985 previous hysterotomy (32.73% -274 cases) was the main indications for Cesarean section.     

Maternal and neonatal morbidity after elective repeat Cesarean delivery versus a trial of labor after previous Cesarean delivery in a community teaching hospital.

OBJECTIVE: To compare maternal and fetal outcomes after elective repeat Cesarean section versus a trial of labor in women after one prior uterine scar. STUDY DESIGN: All women with a previous single low transverse Cesarean section delivered at term with no contraindications to vaginal delivery were retrospectively identified in our database from January 1995 to October 1998. Outcomes were first analyzed by comparing mother-neonate dyads delivered by elective repeat Cesarean section to those undergoing a trial of labor. Secondarily, outcomes of mother-neonatal dyads who achieved a vaginal delivery or failed a trial of labor were compared to those who had elective repeat Cesarean delivery. RESULTS: Of 1408 deliveries, 749/927 (81%) had a successful vaginal birth after a prior Cesarean delivery. There were no differences in the rates of transfusion, infection, uterine rupture and operative injury when comparing trial of labor versus elective repeat Cesarean delivery. Neonates delivered by elective repeat Cesarean delivery were of earlier gestation and had higher rates of respiratory complications (p < 0.05). Mother-neonatal dyads with a failed trial of labor sustained the greatest risk of complications. CONCLUSION: Overall, neonatal and maternal outcomes compared favorably among women undergoing a trial of labor versus elective repeat Cesarean delivery. The majority of morbidity was associated with a failed trial of labor. Better selection of women likely to have a successful vaginal birth after a prior Cesarean delivery would be expected to decrease the risks of trial of labor.     

剖宫产术后非计划再次手术19例临床分析

目的:分析剖宫产患者发生非计划再次手术的原因、高危因素,以及再次手术的注意事项,提高对危险因素的识别,探讨减少和避免其发生的方法。方法:对安徽省妇幼保健院产科2013年1月-2017年7月发生的19例非计划再次手术的剖宫产患者临床资料进行回顾性分析。结果:剖宫产术后非计划再次手术的发生率为0.06%(19/31 136)。首次剖宫产指征包括:胎盘因素6例,多胎妊娠4例,瘢痕子宫4例,头盆不称2例,社会因素2例,巨大儿1例。其中首次手术为择期者15例,急诊者4例。再次剖腹探查术主要指征为因宫缩乏力导致产后出血再次手术7例,胎盘因素4例,腹壁血肿2例,膀胱破裂2例,腹腔内出血2例,子宫切口裂开1例,子宫切口感染1例。再次手术的方式:7例行子宫切除,3例行腹壁血肿清除术,2例行B-lynch缝合术,2例行腹腔血肿清除术,2例行膀胱修补术,1例放置Bakri产后止血球囊,1例行腹腔镜下子宫切口修补术,1例行腹腔镜检查。19例患者均治愈。结论:剖宫产患者发生非计划再次手术的主要原因是宫缩乏力导致的产后出血,首次手术指征为胎盘因素、多胎妊娠以及瘢痕子宫者非计划再次手术风险较高。虽然发生率不高,但造成的不良后果严重,必须采取相应措施,减少和避免非计划再次手术的发生。     

妊娠合并子宫肌瘤130例临床分析

目的探讨妊娠合并子宫肌瘤的临床处理。方法回顾性分析我院5年来130例妊娠合并子宫肌瘤患者处理方法以及产科结局。结果发现妊娠期间肌瘤增大者共11例，72．73％发生于孕早中期，变性类型多样，红色变性占57．69％；130例妊娠合并子宫肌瘤者中，发生早产14例，占10．77％(14／130)，发生产后出血6例，占4．62％(6／130)，其发生率高低与肌瘤的数量、部位及大小之间无明显关系；剖宫产者122例，占93．85％。结论妊娠合并子宫肌瘤易发生各种产科并发症，剖宫产率高，剖宫产术中行肌瘤剔除术应慎重。     

Cesarean section--indications and risks in rural Zaire

In a retrospective study in rural Zaire, 10.2% of all deliveries were conducted by cesarean section. Common indications were contracted pelvis and uterine dysfunction (37%) and previous cesarean delivery (32%). Compared with normal delivery, mortality was higher after cesarean section. Cesarean section should only be performed by well-trained personnel and when vaginal delivery is deemed inappropriate.     

Maternal and neonatal morbidity after elective repeat Cesarean delivery versus a trial of labor after previous Cesarean delivery in a community teaching hospital

Objective: To compare maternal and fetal outcomes after elective repeat Cesarean section versus a trial of labor in women after one prior uterine scar.

Study design: All women with a previous single low transverse Cesarean section delivered at term with no contraindications to vaginal delivery were retrospectively identified in our database from January 1995 to October 1998. Outcomes were first analyzed by comparing mother–neonate dyads delivered by elective repeat Cesarean section to those undergoing a trial of labor. Secondarily, outcomes of mother–neonatal dyads who achieved a vaginal delivery or failed a trial of labor were compared to those who had elective repeat Cesarean delivery.

Results: Of 1408 deliveries, 749/927 (81%) had a successful vaginal birth after a prior Cesarean delivery. There were no differences in the rates of transfusion, infection, uterine rupture and operative injury when comparing trial of labor versus elective repeat Cesarean delivery. Neonates delivered by elective repeat Cesarean delivery were of earlier gestation and had higher rates of respiratory complications (p?<?0.05). Mother–neonatal dyads with a failed trial of labor sustained the greatest risk of complications.

Conclusion: Overall, neonatal and maternal outcomes compared favorably among women undergoing a trial of labor versus elective repeat Cesarean delivery. The majority of morbidity was associated with a failed trial of labor. Better selection of women likely to have a successful vaginal birth after a prior Cesarean delivery would be expected to decrease the risks of trial of labor.     

Extrusion of fetus into the abdominal cavity following complete rupture of uterus: a case report

A gravida 10 para 9, after one Cesarean section (CS) followed by four vaginal deliveries was admitted at term without uterine contractions complaining of abdominal pain. The type of uterine scar was unknown. Severe bradycardia was observed at admission and an emergency Cesarean section was performed. A complete uterine rupture was revealed, the fetus in intact membranes and placenta were found in the abdominal cavity.     

Recurrent uterine rupture after abdominal pregnancy.

Uterine rupture can occur at any time throughout gestation. We present a woman with a previous Cesarean section followed by an abdominal pregnancy. In her next pregnancy, complete uterine rupture resulted in an emergency laparotomy. This case is unique in that it gives insight into the variable presentations of uterine rupture and the risks associated with prior Cesarean sections.     

Uterine rupture secondary to placenta percreta in a near-term pregnant woman with a history of hysterotomy

Uterine rupture during near-term pregnancy is a life-threatening condition. A 31-year-old pregnant woman with a breech presentation at the gestation age of 35(+2) weeks had complained of a dull abdominal pain for days. She was treated 2 years ago with bilateral uterine artery ligation and hysterotomy for removal of the retained placenta. An aggravation of abdominal pain occurred suddenly 4 h after hospitalization. The cardiotocogram showed a fetal heart beat with loss of variability, but increasing deceleration. An urgent cesarean section was performed because of suspected placenta abruption. After successful delivery of the fetus, a protruding placental tissue was found on the fundal uterine wall. We performed wedge resection of the ruptured uterine wall with the aid of an intrauterine muscle injection of 20 IU oxytocin, a local injection of diluted vasopressin (1:60) into the myometrium around and into the rupture site, an intramuscular injection of 0.2 mg methylergonovine, and primary repair of the defect, but in vain. Cesarean hysterectomy was used to control the intractable bleeding. The accumulated blood loss was more than 10,000 mL. The final pathology confirmed placenta percreta with uterine rupture. Luckily, both mother and fetus recovered well and were discharged 7 days later. We concluded that women with retained placenta and/or postpartum hemorrhage managed by previous hysterotomy and uterine artery ligation still need careful prenatal care, since the possibility of re-occurrence of the placenta percreta is easily overlooked and may result in a further life-threatening situation, such as the uterine rupture in this case.     

Early abdominal second interventions following gynecologic surgery]

Relaparotomies in the early postoperative period had to be performed after abdominal gynaecologic procedures in 1,180/00 after vaginal operations in 0,180/00 and after caesarean sections in 3,910/00 of all cases. The indications for the reoperation were: intestinal obstruction (6), hemorrhage (4), paralytic ileus (3), defect of the uterine wall after caesarean section (1) and after enucleation of a fibroid (1), acute appendicitis (1) and peritoneal shock (1). After the 2nd operation 2 patients died; 1 relaparotomy could have been avoided if a septic thrombosis of the right ovarian vein would not have been mistaken for an acute appendicitis.     

Controversy on the method of sterilization during cesarean section: tubal ligation or hysterectomy? Review of the literature

During 1982-1992, 111 cesarean sections followed by 109 tubal ligations (Pomeroy method) and two hysterectomies were performed at two hospitals in Yaounde, Cameroon. All the patients were informed of the necessity of limiting births because of risks posed by future pregnancies. All women gave informed consent. The leading indications for cesarean section were limited pelvis associated with previous cesarean section(s)-related scarred uterus (59 cases) and fetal distress (33 cases). The two principal indications for tubal ligation were previous cesarean sections (64 cases) and grand multiparity (i.e., 5 births) (45 cases). 37.1% of tubal ligation cases had more than five children. The number of tubal ligation cases after cesarean section was highest in 1983 (16 cases), 1984 (13 cases), 1990 (16 cases), 1991 (13 cases), and 1992 (12 cases). No woman younger than 24 years old underwent tubal ligation. 77.1% of tubal ligations occurred to women aged 30-40. Immediate hysterectomy was required in two cases to control severe hemorrhaging. Three tubal ligation cases lost more than 1000 cc of blood and had to be transfused. All 111 cesarean section cases received prophylactic antibiotics. The surgeon perforated the bladder of a patient who had had three previous cesarean sections when he/she dissected the lower segment of the peritoneal cavity. This case suffered no postoperative complications. Surgeons had to reintervene two hours after the tubal ligation because the ligature thread loosened at the level of the two fallopian tubes, causing a hemorrhage. No one developed fever. There were no fetal or maternal deaths. The peri- and post-operative complication rate was lower than that of other like studies. The researchers recommend tubal ligation as the preferable sterilization method after cesarean section. Hysterectomy should only be used in cases of severe hemorrhaging which can lead to maternal death.     

Analysis of 65 cases of abruptio placenta]

From Jan 1, 1971 to Dec 12, 1990, 65 cases of abruptio placenta were admitted to our hospital. The incidence was 0.19%. Among them, thirty were complicated by pregnancy induced hypertension (46.2%). The perinatal fetal mortality was 19.7%; perinatal death occurred mostly in the premature group. All babies survived except two abnormalities. Cesarean section rate was 32.3%. All postpartum hemorrhage 29.2%. Couvelaire uterus 6.2%, were cured by conservative treatment. There was neither stillbirth nor newborn death in the thirty three cases treated expectant, but a newborn asphyxia rate of 6.1% and a cesarean section rate of 15.1%. Analysis showed that abruptio placentae should be suspected in cases with abnormal fetal heart rate of unknown cause accompanying signs of labor, premature labor of unknown cause, uterine tongue, ultrasonically visualized liquid from dark area behind the placenta, besides classical signs of abdominal pain and vaginal bleeding. Expectant treatment is appropriate if gestational age is small and no acute symptoms exists so as to minimize the perinatal mortality and cesarean section rate.     

Emergency peripartum hysterectomy: a 9-year review

Objective: To determine the incidence, indications, risk factors, and complications of emergency peripartum hysterectomy. Study design: A retrospective study of the patients requiring an emergency peripartum hysterectomy of a 9-year period was conducted. Emergency peripartum hysterectomy was defined as one performed for hemorrhage unresponsive to other treatment less than 24 h after delivery. Demographic and clinical variables were obtained from the maternal records. Results: There were 34 emergency peripartum hysterectomies out of 117,095 deliveries for a rate of 0.29 per 1,000. Of the 16 cases that were delivered by cesarean section, seven had a previous cesarean section and 18 cases were delivered vaginally, including two using vacuum extraction. Total hysterectomy was performed in 24 patients, and subtotal hysterectomy in ten patients. The indications for hysterectomy were uterine rupture (n=12), placenta accreta (n=10), uterine atony (n=7), and hemorrhage (n=5). There were two maternal deaths, six stillbirths, and two early neonatal deaths. Conclusion: This study identified surgical deliveries, uterine rupture, placenta accreta, and uterine atony as risk factors for emergency peripartum hysterectomy. The most common reason for abnormal placental adherence was a previous cesarean section. Multiparity and oxytocin use for uterine stimulation were among the risk factors for uterine atony that necessitated emergency peripartum hysterectomy.     

复杂性前置胎盘术中止血技巧及术中处理

复杂性前置胎盘的剖宫产术手术复杂、难度大。避免大量出血、器官丢失和孕产妇死亡是其主要目的。手术从腹壁切口及子宫切口的选择、胎盘的个体化处置、手术保守治疗、子宫切除等方面都有其特殊性。各种处理方法都应严格掌握适应证、规范操作步骤,并灵活应用各种方法,才能获得最好的临床效果。     

Ligature des artères iliaques internes face aux hémorragies obstétricales graves en milieu africain

ObjectivesAssess the efficiency of internal iliac arteries ligation in intractable obstetrical hemorrhage and ascertain success or failure factors.Patients and methodsIt was a retrospective study which concerned 159 patients who underwent internal iliac arteries ligation for persistent and severe obstetrical hemorrhage from March 1992 to February  2007. Arrest of hemorrhage after ligation with survival of the patient was considered as successful; was considered as failure, persistence of hemorrhage in spite of the ligation or patient death.ResultsInternal iliac arteries ligation allowed hemorrhage control in 84,3% of cases. Main etiology of hemorrhage were: uterine atony (42,8%), abruptio placentae (31,4%). Coagulation disorders and hypovolemic shock, consequences of long delay of management were identified as bad prognosis factors. Blood transfusion was also singled out as a factor likely to ameliorate prognosis, especially in hemodynamic precarious situations. Surgical complications incidence was 1,89%, represented by two internal iliac vein lesions and one ureteral section successfully repaired.Discussion and conclusionInternal iliac arteries ligation is a prerequisite treatment of severe postpartum hemorrhage. The outcome is better when it is performed precociously (p = 0,0000003) before the happening of disseminated intra vascular coagulation (p = 0,006), hemodynamic troubles (p = 0,0099) and acute severe anemia (p = 0,02). It is a good alternative to arterial embolization in Africa.     

Hypogastric artery ligation for intractable pelvic hemorrhage.

OBJECTIVE: To assess the outcomes of bilateral hypogastric (internal iliac) ligation performed to control intractable pelvic hemorrhage and avoid hysterectomy. METHODS: A review of indications and outcomes for 117 cases of bilateral hypogastric artery ligation over 15 years (1990-2004). RESULTS: Apart from a slight lesion to the hypogastric vein, no complications were observed. Hemorrhage was effectively controlled in all 37 obstetric cases. In 13 of these cases, the uterus was preserved even when there was cervical pregnancy, placenta previa, placental abruption, uterine atony, and uterine rupture, and 4 women were delivered of mature infants. Hemorrhage was effectively controlled in 41 of 80 gynecologic cases. Prophylactic reduction of pelvic blood flow was the indication for the procedure in 39 cases, 5 of whom involving Jehovah's Witnesses adverse to blood transfusion. The uterus was preserved in only a few of the 41 controlled cases, but one woman (so far) was delivered of a mature infant. CONCLUSION: Hypogastric artery ligation was found to be indicated if (1) life-threatening pelvic hemorrhage could not be controlled by conservative methods; (2) prophylactic reduction of pelvic blood flow was needed to prevent anticipated hemorrhage; and (3) preservation of reproductive function was desired. The procedure was found to be safe and usually effective and should be taught during obstetric and gynecologic training.