白癜风患者生活质量调查

目的:运用DLQI量表调查白癜风患者生活质量,评估白癜风对患者生活质量的影响。方法:本次调查采用中文版皮肤病生活质量指数调查表(DLQI)评估白癜风对患者生活质量的影响。结果:DLQI平均得分为(7.80±5.30)分,最小值为0分,最大值为20分;42.86%的患者生活质量有少许影响,28.57%的患者生活质量有相当影响,25.51%的患者生活质量有很大影响;且临床分型及分期对白癜风患者生活质量有一定影响,DLQI得分与皮损面积呈显著正相关。结论:白癜风对患者的生活质量有一定影响,白癜风的治疗与心理疏通应及早进行。     

全程护理模式对白癜风患者自体表皮移植术疗效及术后生活质量的影响

分析全程护理模式在白癜风患者自体表皮移植术中的应用效果及对生活质量的影响。方法 选择2022年1月-2023年1月贵州医科大学附属医院皮肤科收治的100例白癜风自体表皮移植术患者为研究对象,随机分成参照组与试验组,各50例。参照组实施常规性术后护理模式,试验组实施全程护理模式,比较两组护理效果、术后疼痛情况及生活质量。结果 试验组护理总有效率为98.00%,高于参照组的84.00%（P ＜0.05）;试验组疼痛（NRS）评分低于参照组（P ＜0.05）;试验组生活质量（SF-36）各项评分均高于参照组（P ＜0.05）。结论 全程护理能够让自体表皮移植术后的白癜风患者改善机体的皮肤状态,可以提高患者的恢复速度,减轻疼痛,改善患者生活质量,值得应用。     

痤疮患者生活质量调查分析

目的：通过对痤疮患者生活质量的调查及评分,了解痤疮对患者日常生活的影响及综合治疗的临床效果。方法：选择符合入选标准的痤疮患者,于治疗前后分别填写皮肤病生活质量指数（Dermatology Life Quality Index,DLQI）问卷,根据病情分级给予不同治疗。结果：治疗前得分（11.86±5.13）分,治疗后得分（8.43±3.68）分,治疗前后得分比较t=5.91,P〈0.001,差异有显著性。结论：DLQI评分表对观察痤疮患者的生活质量和治疗效果更加直观。     

白癜风患者心理健康状况调查分析

目的了解白癜风患者的心理健康状态，探讨相应的心理护理措施。方法采用症状自评量表（SCL-90）、应付方式问卷（CSQ）对44例白癜风患者进行心理状态调查，并与常模及34例慢性湿疹患者进行比较。结果白癜风患者在强迫、人际关系、抑郁、焦虑、敌对、恐怖及精神病性7个方面评分均显著高于常模和慢性湿疹患者（P〈0．05，P〈0．01），其幻想、退避评分显著高于慢性湿疹患者（P〈0．01，P〈0．05）。结论白癜风患者的心理健康状况较差，常采用不成熟的应付方式进而产生社交危机感，有针对性地实施心理护理对其治疗和预后有重要意义。     

白癜风患者心理健康状况调查分析

目的了解白癜风患者的心理健康状态,探讨相应的心理护理措施.方法采用症状自评量表(SCL-90)、应付方式问卷(CSQ)对44例白癜风患者进行心理状态调查,并与常模及34例慢性湿疹患者进行比较.结果白癜风患者在强迫、人际关系、抑郁、焦虑、敌对、恐怖及精神病性7个方面评分均显著高于常模和慢性湿疹患者(P＜0.05,P＜0.01),其幻想、退避评分显著高于慢性湿疹患者(P＜0.01,P＜0.05).结论白癜风患者的心理健康状况较差,常采用不成熟的应付方式进而产生社交危机感.有针对性地实施心理护理对其治疗和预后有重要意义.     

慢性前列腺炎患者生活质量临床调查

目的调查慢性前列腺炎(chronic prostatitis,CP)患者生活质量及性生活质量状况并分析影响生活质量及性生活质量的相关因素;方法随机选择CP患者,无记名填写CP症状评分量表(NIH-CPSI)、性功能评价表及年龄、病程等,并进行统计分析。结果CP总症状评分5~35分,平均(20.69±7.02)分;生活质量评分2~12分,平均(8.47±2.49)分;性生活质量总分18~53分,平均(38.79±7.55)分;生活质量评分与前列腺炎症状总分、疼痛及排尿症状评分之间有显著相关性;与性功能总评分、射精潜伏期、射精控制能力、性生活满意度、性生活自信度及性生活焦虑评分之间有显著相关性,与年龄、病程、前列腺液内白细胞及卵磷脂数量无显著相关性。结论CP导致生活质量、性生活质量下降,生活质量下降与患者CP症状、性功能下降、性生活满意度降低及配偶性生活满意度降低有关,生活质量及性生活质量下降与年龄、病程及前列腺液内白细胞及卵磷脂数量无明显相关性。     

白癜风患者心理调查与结果分析

目的:对白癜风患者心理进行调查并作结果分析。方法:采用心理健康症状自评量表(SCL-90)、汉密尔顿抑郁量表(HAMD)以及汉密尔顿焦虑量表(HAMA),对40例暴露部位白癜风患者和30例非暴露部位白癜风患者进行问卷调查分析。结果:SCL-90测评结果显示:白癜风患者暴露组、白癜风患者非暴露组在人际关系、焦虑和抑郁项的得分明显高于对照组,差异有显著性(P<0.05)。HAMD、HAMA测评结果显示:白癜风患者暴露组、白癜风患者非暴露组的得分明显高于对照组,差异有显著性(P<0.05)。白癜风患者暴露组HAMA得分大于14分,存在焦虑症状。结论:白癜风患者可能存在焦虑、抑郁等心理障碍,本研究为白癜风患者的心理干预治疗提供了依据。     

白癜风的心理干预治疗作用评估

目的 探讨心理干预治疗在白癜风治疗中的作用.方法 对120例白癜风患者进行心理健康症状自评量表(SCL-90)问卷调查,评价受试者心理健康状况.有心理问题的66例随机分为Ⅰ、Ⅱ组,无心理问题的54例随机分为Ⅲ、Ⅳ组.Ⅰ、Ⅲ组采用心理干预+药物+光疗,Ⅱ、Ⅳ组为单纯药物+光疗治疗,疗程3个月,评价疗效同时再次进行心理测评,计算4组治疗方案的P值,评价患者心理问题的改善和皮损好转显效率的对应程度.结果 Ⅰ组与Ⅱ组对比,显效率差异有统计学意义(P＜0.05);Ⅲ与Ⅳ组对比,显效率差异无统计学意义(P＞0.05);Ⅰ组与Ⅲ组对比,显效率差异有统计学意义(P＜0.05);Ⅱ组与Ⅳ组对照,显效率差异无统计学意义(P＞0.05).结论 对白癜风患者进行心理干预治疗,有助于提高早期疗效和生活质量.     

贵阳市维持性血液透析患者生活质量调查

目的了解贵阳市终末期。肾脏疾病（end stage renal disease,ESIm）接受维持性血液透析患者的一般状况、病因构成和生活质量现状。方法收集贵阳市12个血液透析中心ESRD血液透析患者756例患者的一般资料、透析方法、肾脏病和生活质量问卷（KDQOL-SF36量表）等信息并进行分布特征描述。结果756例患者中,男女之比为1．45：1．00;平均年龄（49．1±14．7）岁,原发病前三位分别为慢性肾小球肾炎407例（占53．84％）、糖尿病肾脏病132例（占17．46％）、高血压。肾损害124例（占16．40％）;患者月均总医疗费用为（6072．55±3381．01）元;不同透析时间的血液透析患者’肾脏病和透析相关生活质量各维度得分具有显著差异（P〈0．05）。结论贵阳市维持血液透析患者中,其原发病以慢性肾小球肾炎为主;透析时间〉60个月的血液透析患者生活质量、一般健康相关生活质量各维度得分较低。     

150例白癜风患者个性特征的调查分析

目的：探讨白癜风患者的个性特征。方法：应用艾森克个性问卷（Eysenck personality questionnaire,EPQ）（成人版）,对150例16～70岁的白癜风患者进行测试,并进一步与全国常模比较EPQ各量表粗分均值,T值及个性构成。结果：白癜风男性患者中P、E、N、L分值均高于常模（P分值P〈0.05,E、N、L分值P〈0.01）;女性患者中P、E分值均高于常模（P〈0.01）,但不同性别各组间无显著性差异。结论：白癜风患者具有外向、精神质的个性特征,提示白癜风患者的个性特征可能是疾病发生与复发的原因之一,建议在对白癜风病患者进行药物治疗的同时,应及时予以心理关注和干预。     

Quality of life and illness perceptions in patients with recently diagnosed head and neck cancer

BACKGROUND: The purpose of this study was to investigate which illness perceptions of patients recently diagnosed with head and neck cancer explain variance in their quality of life (QOL) to identify potential targets for interventions aimed at improving QOL. METHODS: Sixty-eight patients (mainly with stage III and IV disease) completed the Illness Perception Questionnaire-Revised (IPQ-R) and the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30). RESULTS: Pretreatment cross-sectional results from this prospective study show that, after controlling for age and comorbidity, illness perceptions were significantly related to the QLQ-C30 physical, role, emotional, cognitive, social functioning, and global health subscales. Patients with increased attention to symptoms, who believed in a greater likelihood of recurrence, who were more likely to engage in self-blame, and who had a stronger emotional reaction to the illness had lower QOL scores. CONCLUSION: Our results suggest that restructuring negative pretreatment illness perceptions may help patients to cope more adequately during and after treatment.     

Concomitant twice-a-day radiotherapy and chemotherapy in unresectable head and neck cancer patients: A long-term quality of life analysis.

BACKGROUND: The purpose of this study is to make a comparative analysis between acute toxicity with late toxicity. This study is based upon a French quality of life (QoL) questionnaire in a cohort of advanced head and neck (H&N) cancer patients treated by concomitant twice-a-day continuous radiotherapy with no acceleration and chemotherapy with cisplatin and 5-fluorouracil. METHODS: From September 1992 to November 1997, a prospective data bank of 91 patients was constituted. In November 1999, 31 patients were still alive and followed for more than 3 years. All patients had stage IV strictly unresectable squamous cell carcinoma of oropharynx or hypopharynx. A French specific H&N cancer QoL questionnaire was used at the end of radiotherapy and at the last date of follow-up of each patient (during 1999). p values reflect comparison of percentages obtained at the end of treatment with percentages at long-term follow-up. Statistical analysis was performed using chi(2) test (p <.05 considered as significant). Percentages obtained by the QoL questionnaire correspond to moderate-severe problems only. RESULTS: Twenty-nine of 31 (94%) patients participated in the QoL study. Acute treatment toxicities were severe with declines in virtually all QoL and functional domains. Globally, with an average long-term follow-up of 4.5 years (range 3-7 years after treatment), there is a statistical improvement in the following symptoms: dry mouth and sticky saliva (97% versus 55%, p <.05); tasting problems (35% versus 21%, not significant); swallowing problems (77% versus 36%, p <.05); and H&N pain (86% versus 9%, p <.05). Financial problems were not improved (21% versus 14%, not significant), and psychological problems (59% versus 5%) were statistically significant. Fourteen of 29 (48%) patients were drinking and 8 of 29 (28%) were smoking at long-term follow-up; at the diagnosis they were 86% and 90%, respectively. At long-term follow-up 22 of 29 presented good or very good QoL, and 25 of 29 said they had improved their initial QoL. CONCLUSION: The interest of twice-a-day radiotherapy with concomitant chemotherapy is to increase total radiotherapy equivalent dose without increasing late toxicity and also to improve locoregional control, survival, and long-term QoL/effectiveness ratio. Best supportive care is recommended to obtain both good QoL and cancer control in a long-term follow-up.     

Health-related quality of life profiles based on survivorship status for head and neck cancer patients

BACKGROUND: As the methodologies for evaluating health-related quality of life (HRQOL) in head and neck cancer patients have matured over the past 10 years, there has been an increasing focus on reporting longitudinal data. These studies have primarily focused on long-term survivors. This study addresses the HRQOL of both long-term and short-term survivors. METHODS: This is a prospective, longitudinal study of 479 head and neck cancer patients followed for at least 3 years after diagnosis. Analysis of longitudinally collected HRQOL scores was based on survivorship status. RESULTS: The HRQOL for 3 survivorship groups: short-term (died <1 year), intermediate-term (died 1-3 years), and long-term survivors (alive >3 years) were different at all time points (pretreatment, 3, 6, and 12 months). Differences were greatest between the short-term and long-term survivors. Long-term survivors demonstrated the best HRQOL and an improving HRQOL trajectory at 12 months. The HRQOL of short-term survivors declined precipitously throughout all available follow-up. Intermediate-term survivors did show some improvement following treatment but had a declining HRQOL trajectory at 12 months. CONCLUSION: The HRQOL profiles of head and neck cancer patients differed significantly depending on survivorship status. Long-term HRQOL results should be analyzed within the context of the results for all of the patients eligible to have been included in the initial study cohort.     

Effects of psychosocial intervention on quality of life in patients with head and neck cancer

BACKGROUND: A longitudinal, prospective, case-control study evaluated if a psychosocial support program improved health-related quality of life (HRQL) in head and neck (H&N) cancer patients. METHODS: One hundred forty-four H&N cancer patients were included: 52 study patients and 92 controls. The study group met the support team repeatedly throughout the first year after diagnosis. HRQL was assessed three times during the first year and after 3 years using the EORTC QLQ-C30, EORTC QLQ-H&N35, and HADS. RESULTS: A few statistically significant differences were found, all favoring the controls. Controls reported better global quality of life after 1 year and felt less ill after 3 years. Depression and treatment-related side effects were prevalent in both groups. CONCLUSIONS: Our psychosocial support program did not improve HRQL in H&N cancer patients. Its effectiveness may be improved by evaluating and actively integrating HRQL assessments during the program, thereby enabling rapid and adequate symptomatic treatment and/or psychologic intervention.     

Short-term and long-term quality of life after neck dissection.

INTRODUCTION: Quality of life (QOL) is an important outcome measure in cancer therapy. Neck dissection (ND) morbidity has been well studied, but no study has focused on the quality of life after ND specifically. METHODS: Fifty-one patients who have undergone ND completed a 6-item quality-of-life survey with a 7-point frequency and interference response scale. General QOL and comorbidity biases were evaluated with the SF-12 questionnaire and the Charlson comorbidity index. RESULTS: The following symptoms were the most commonly experienced after surgery: neck tightness (71%), numbness or burning of the ear (57%), and shoulder discomfort (53%). However, interference with daily activities was reported by only 37%, 32%, and 33% of patients with these symptoms, respectively. Within 2 years of surgery, interference with daily activities decreased to 17%, 18%, and 12%, respectively. QOL after ND was negatively associated with previous radiation, previous chemotherapy, tumor stage, and more radical neck surgery but was positively associated with time after surgery. Shoulder discomfort and neck tightness had the greatest affect on QOL. CONCLUSIONS: Our results suggest that patients should receive preoperative counseling regarding the morbidities from ND and the possible short-term and long-term impact on QOL. Further studies evaluating the relationship between primary tumor characteristics and quality of life after ND need to be undertaken.