IPS Empress Ⅱ铸瓷贴面修复前牙切角缺损的临床疗效评价

目的观察并评价IPS Empress Ⅱ铸瓷贴面对前牙小面积切角缺损修复的临床效果。方法对42位前牙小面积切角缺损患者,总计65颗患牙行IPS Empress Ⅱ铸瓷贴面美容修复,患者修复后3年内（6个月、1年、2年、3年）定期复诊,检查基牙与贴面边缘密合度、修复体颜色、解剖形态、及修复体有无折裂,并评价临床疗效。结果修复后3年IPS Empress Ⅱ铸瓷贴面的完整保存率及边缘适合性达到98.4%,有少数牙刚修复后有轻度牙龈炎及牙本质敏感,但2年后症状消失。颜色匹配效果稳定,患者均比较满意。结论IPS Empress Ⅱ铸瓷贴面是前牙切角缺损较理想的一种修复方法。     

IPS Empress 2铸瓷技术在前牙修复中的应用

目的:探讨利用IPS Empress 2铸瓷技术进行前牙修复的修复效果,供临床应用参考.方法:对79例患者的106颗前牙用IPS Empress 2铸瓷技术进行修复,参考美国健康协会的修正标准进行临床效果评价.结果:修复体的外形、边缘密合性、继发龋、边缘着色、颜色匹配情况良好.结论:IPS Em-press 2铸瓷临床修复效果令人满意.     

口腔全瓷冠桥的临床修复效果

目的评价IPS Empress2全瓷冠桥的临床修复效果。方法对制作了46件IPS EmPress2全瓷冠桥的36例患者进行临床修复评价,戴用期为6-24个月,对修复体边缘完整性,解剖外形,颜色,表面等进行临床评价,菌斑指数和牙眼指数与对照组采用Wilcoxon秩和检验进行比较。结果IPS Empress2全瓷冠桥的满意率为97.3%。结论IPS Empress2全瓷冠桥的近期修复效果良好。     

IPS—Empress 2全瓷冠在四环素牙美容修复中的疗效观察

目的：评价IPS—Empress 2全瓷冠在四环素牙美容修复中的应用效果。方法：对64颗四环素牙严格按照全瓷冠的要求进行修复,用美国公共健康协会的修正标准进行评价。结果：64颗全瓷冠桥修复体经6～24个月的随访观察,成功58颗,失败6颗,其中修复体颜色不协调2颗,边缘着色1颗,边缘不密合1颗,折裂2颗,成功率为90．63％。结论：IPS—Empress 2全瓷冠桥在四环素牙的美容修复中效果满意,是一种较理想的美容修复材料。     

应用瓷贴面美容修复上切牙的临床疗效观察

目的总结瓷贴面美容上切牙的临床疗效,评价该技术在牙科美容中的作用。方法54例患者共计60颗上切牙切角小面积牙体缺损患牙,根据患牙缺损的大小进行牙体预备,要求牙体预备的范围达缺损区域以外约2mm,常规制作IPS—Empress Ⅱ瓷贴面,常规粘结。美容修复完成后随访2年,检查基牙与贴面边缘密合度、边缘着色、修复体颜色、解剖形态、有无修复体周围龋及修复体有无折裂。结果2年内,60颗上切牙修复体各项检查指标均未发现异常情况,修复效果良好。结论瓷贴面修复体对上切牙的美容修复效果满意,可作为上切牙切角缺损首选的修复方法。     

铸瓷贴面在前牙美容修复上的应用

目的 观察铸瓷贴面用于前牙美容修复的临床效果。方法对修复科门诊患者26例，共126颗前牙、双尖牙用铸瓷贴面修复，观察修复体的形态、色泽、牙龈健康状况。结果铸瓷贴面用于前牙美容修复，牙体形态、牙龈健康状况良好，色泽有待进一步改进。结论铸瓷贴面用于前牙美容修复具有较好的疗效。     

全瓷贴面修复的临床观察

目的评价全瓷贴面修复技术治疗前牙缺损、间隙和变色的临床效果。方法70例患者,252颗牙分成两组,试验组126颗牙,以IPS Empress 2全瓷贴面修复技术修复;对照组126颗牙,以镍铬合金烤瓷冠修复。采用根据美国加州牙科协会的评价标准和改良Ryge贴面复查标准的修正标准,对其临床结果进行追踪评价。结果经3年的临床观察,试验组在颜色满意程度、边缘适合性、邻边缘变色、术后敏感、牙龈着色、牙龈反应方面均优于对照组(P<0.01~0.001),修复体完整度方面,两组无显著性差异(P>0.05)。结论IPS Empress 2全瓷贴面修复技术治疗前牙缺损、间隙和变色的临床效果令人满意。     

关于预成瓷贴面的修复

目前 ,临床采用贴面方法对牙齿进行美容修复者日益增多。本文作者自 1999年开始对 175例门诊患者 30 5颗牙进行了预成瓷贴面的修复。经临床观察 16 8例完好 ,9例失败。现将临床体会介绍如下。1　瓷贴面修复的适应证①前牙因四环素着色氟斑牙釉质发育不全及死髓牙变色的美容修复 ;②腭舌向异位牙、过小牙 ,牙间隙等因素大小或形态异常前牙的美容修复 ;③前牙因龋坏或外伤折断等所导致牙体组织缺损的修复 ;④在无烤瓷修复的条件下 ,可用作前牙人工冠桥的唇面。2　瓷贴面的禁忌证①牙体组织缺损过多 ,不能获得足够的釉质粘结面者 ;②咬合关系过…     

上颌前牙区IPS—EmpressⅢ铸瓷贴面的临床效果

目的：观察上颌前牙区IPS-EmpressⅢ铸瓷贴面效果,评价该技术在前牙美容修复中的应用价值.方法：选择21例69颗上颌前牙,唇侧开窗预备,行铸瓷贴面修复,于粘接修复后2周、6个月、1年、2年、3年,依据改良Ryge评价标准对修复体完整度、边缘适合度、牙龈炎性反应、舒适度、颜色匹配等进行调查,评价效果.结果：98％以上的贴面完整存在,并有良好的边缘适合度;1颗贴面有切端小缺损,1颗贴面脱落;2周复查时2颗牙有牙龈炎症,此后明显改善;5颗牙有明显牙敏感症状,经脱敏处理后缓解;无继发龋、边缘变色及明显的颜色不协调.结论：IPS-EmpressⅢ铸瓷贴面修复是一种理想的前牙美容修复方法.     

应用IPS e．max Press铸瓷全冠美容修复前牙的临床研究

目的评价应用IPS e．max Press铸瓷全冠美容修复前牙的临床疗效。方法选择2008—2010年间于我院就诊的37例IPS e．max Press铸瓷全冠美容修复前牙患者、共计60颗牙单位为研究对象,修复后12．6（3～24）个月根据美国公共健康协会的修正标准对修复体进行评价,并调查满意度。结果24个月的追踪调查显示,34个修复体中,折断并脱落1个,97％的铸瓷全冠边缘密合,97％有健康的牙龈,未发现继发龋、边缘变色及明显颜色不协调。由医生、患者、社会其他人群所做的满意度调查,总体满意度超过80％。结论IPS e．max Press铸瓷全冠修复体可获得理想的前牙美学修复效果,具有较高的临床应用价值。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.