共查询到20条相似文献，搜索用时 15 毫秒
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E.M. Le Coustumier E. Denes C. Martin P. Weinbreck 《La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne》2017,38(2):81-89
Introduction
Nocardiosis are uncommon. The diagnosis may be difficult, with significant morbidity and mortality, often occurring on frail patients. Few data are available in France.Methods
A retrospective single center study was conducted from 2002 to 2014 and included all patients with at least one positive microbiological sample for Nocardia with a follow-up in our hospital.Results
Nineteen patients, including 15 men, were included with a mean age of 58 years (25–85). Seventeen had a risk factor (lung diseases [13], corticosteroids [12], solid neoplasia [2], HIV infection [2], diabetes mellitus [3], kidney transplant [2], lymphopenia [1]). Infections’ locations were: pulmonary (12), brain (3), skin (2), lymph node (1) and corneal (1). The slow growth leads to a median of 35 days for a positive result (3–95). Nine species were identified. Fifteen patients (79%) received one or more lines of antibiotics including: cotrimoxazole (9), amoxicillin (7) cefotaxime/ceftriaxone (7) imipenem (3), or amikacin (3). The average duration of antibiotic therapy was 207 days. Four patients did not receive antibiotics due to a late result or a bacterial co-infection masking nocardiosis. Five patients died (26%) including 2 with cerebral nocardiosis. Six patients were cured, 4 suffered a relapse, 4 had an unknown evolution, and 1 was still treated.Conclusion
Our study shows that nocardiosis is a disease difficult to treat. A better understanding of this type of infection is necessary. 相似文献4.
M. Koubaa F. Smaoui S. Gargouri H. Ben Ayed K. Rekik I. Abid I. Maaloul J. Feki C. Marrakchi M. Ben Jemaa 《La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne》2018,39(5):326-331
Objectives
Ocular tuberculosis is a rare form of extra pulmonary tuberculosis. It represents 1–2% of all clinical forms. The aim of this work was to focus on diagnostic and therapeutic characteristics of ocular tuberculosis.Methods
We report a case series of 14 patients with ocular tuberculosis seen in an infectious diseases department between 2006 and 2015. The diagnosis was retained on clinical data and a positive tuberculin skin test or interferon-gamma release assay.Results
The patient's mean age was 40.7 ± 9 years. The most common clinical presentation was uveitis (11 patients and 16 eyes). An extra ocular involvement was associated in three patients. The mean duration of antitubercular therapy was 10 ± 2.5 months. Corticosteroid therapy was associated in 11 cases. The outcome was favorable in all cases. Two patients had maintained visual sequelae.Conclusion
Ocular tuberculosis is a rare disease but still remains a diagnostic problem. It should be considered in case of any chronic ocular symptoms, especially in endemic countries. Early management can improve the visual prognosis. 相似文献5.
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M. Delplanque A. Aouba P. Hirsch P. Fenaux J. Graveleau F. Malard D. Roos-Weil N. Belfeki M. Groh S. Guillet J. Razanamahery M. Mahevas G. Maigné S. Miranda T. Quéméneur L. Sailler M. Sebert L. Terriou A. Mekinian 《La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne》2021
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A. Fabre-Baudouin A.L. Roux C. Marin M. Lachatre M. De Laroche M. Ponsoye T. Hanslik S. Trad 《La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne》2017,38(12):794-799
Introduction
Lymphogranuloma venereum (LG) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis L serovar.Methods
These five consecutive cases aim to highlight the risk of LG misdiagnosis, in case of initial presentation with isolated inguinal adenitis.Results
Five men (mean age: 30 ± 7 years) were seen in an internal medicine department, for inguinal adenopathy. One patient had clinical signs of urethritis. None presented an associated rectitis. Three patients had a history of STI, and two had a discovery of related HIV disease. Urinary polymerase chain reaction (PCR) was positive for the symptomatic patient and negative for the others. Lymph node PCR was positive in all patients within a L2b serotype (searched in 4 out of 5 cases).Conclusion
LG should be evoked in any patient with inguinal adenomegaly, particularly in case of STI history or risk factors. Negativity of urinary PCR should lead to further investigations, essentially a lymph node cytopuncture to evidence C. trachomatis. 相似文献14.
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P. S. Diop J. M. Ndoye D. Ndiaye I. Ka J. M. Dangou B. Fall 《Journal Africain d'Hépato-Gastroentérologie》2009,3(4):190-194
Aim
The cancer of the oesophagus because of its poor prognosis is a terrifying digestive tumour. The goal of this work was to appreciate the epidemiologic characteristics, anatomo-clinics and to become it of a series of patients.Patients and methods
It was about a retrospective analysis of 72 records of patients in the same team, followed between January 2004 and December 2007.Results
Squamous cell carcinoma accounted for 94.4% of cancers of the oesophagus during this period. The average age of the patients was 48 years with extremes of 16 and 86 years. The diagnosis was late with six months average time of the clinical symptomatology evolution. The general state was faded with an index of performance WHO superior to 2 at 48.6% of the patients. The high alcohol consumption and smoking, principal exogenic toxic factors risk was found only in 16.6% of the cases. Achalasia and Plummer-Vinson syndrome, squamous cell carcinoma specific factors of risk, were present in 5.6% of the cases. Gastrointestinal oesophageal reflux disease, indirect risk factor of adenocarcinoma, was found in 9.7% of the cases. The disease was advanced with 64% of stages III and IV TNM in classification (UICC 2002). The rate of resecablity was 27.8%. None of our patients had profited from neo-adjuvant treatment. Overall survival at two years was estimated at 2.8%.Conclusion
The pejorative prognosis seemed to be raised by the late diagnosis in our series. An improvement of survival would pass by an early detection. A barium transit in front of all odynophagia, followed by an endoscopic examination if required must be our standard. The mechanism of the viral carcinogenesis by human papillomavirus types 16 and 18 evoked but not completely elucidated is a way of research to decrease the incidence of the cancer of the oesophagus in population exposed to these viruses. 相似文献16.
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A. Mekinian M. Resche-Rigon C. Comarmond P. Cacoub O. Fain D. Saadoun Alessandra Soriano Joel Constants Philippe Alric Patrick Jego Florian Bussato Matthieu Cabon Robin Dhote Lazaro Estibaliz Isabelle Kone Pault Cédric Landron Christian Lavigne Bertrand Lioger Carlo Salvarini 《La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne》2018
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