应对方式对慢性前列腺炎患者预后的影响

目的观察应对方式对慢性前列腺炎预后的影响.方法对62例慢性前列腺炎患者,采用艾森克个性问卷(EPQ)测定患者的个性特征,采用症状自评量表(SCL-90)测定患者心身症状,采用应对分类问卷测定患者的应对方式.结果以消极应对为主的患者趋内向,且心身症状严重,预后较差.结论慢性前列腺炎患者的预后与患者的应对方式及人格特征密切相关.     

慢性前列腺炎患者心理状况与生活质量的相关性分析

目的 探讨慢性前列腺炎(CP)患者心理健康状况与生活质量的关系.方法 采用症状自评量表(SCL-90)和世界卫生组织生活质量测定量表简表(WHOQOL-BREF)评估100例CP患者(观察组)和80例健康体检者(对照组)的心理健康状况和生活质量.结果 观察组的躯体化症状、强迫症状、人际关系敏感、抑郁、焦虑、偏执和总均分明显高于对照组,观察组的生理、心理、社会关系和环境等4个领域的WHOQOL-BREF评分明显低于对照组,差异有统计学意义,均P<0.01.CP患者SCL-90总均分与WHOQOL-BREF的4个领域评分呈显著负相关,均P<0.01.结论 CP患者心理健康状况对生活质量有一定影响,护理人员应结合多种方式,采取有效的护理干预措施,提高其生活质量.     

应对方式对慢性前列腺炎患者预后的影响

目的 观察应对方式对慢性前列腺炎预后的影响。方法 对62例慢性前列腺炎患者，采用艾森克个性问卷(EPQ)测定患者的个性特征，采用症状自评量表(SCL-90)测定患者心身症状，采用应对分类问卷测定患者的应对方式。结果 以消极应对为主的患者趋内向，且心身症状严重，预后较差。结论 慢性前列腺炎患者的预后与患者的应对方式及人格特征密切相关。     

白癜风患者心身状态调查及护理对策

目的:了解白癜风患者心身状态及其影响因素,并探讨相应的护理对策。方法:采用症状自评量表(SCL-90)对67例白癜风患者进行心身状态调查,并将结果与中国常模进行比较。结果:患者的SCL-90各项统计指标与中国常模进行比较,经统计学分析,差异均有统计学意义。结论:慢性前列腺炎患者心理健康水平比普通人群要低,建立良好的护患关系,发挥家庭效用,做好康复护理能有效地减轻或解除患者心身痛苦。     

慢性前列腺炎患者心理健康状况调查及护理对策

目的:调查慢性前列腺炎患者心理健康状况,并探讨相应的护理对策。方法:采用症状自评量表(SCL-90)对67例慢性前列腺炎患者的心理健康状况进行调查,并将结果与中国男性正常人SCL-90评定结果(中国男性常模)作对照统计分析;自行设计表格调查慢性前列腺炎患者心身需求。结果:67例患者的SCL-90各项统计指标,在躯体化、抑郁、焦虑、精神病性4个因子分与中国男性常模比较有差异(P<0.05),人际关系、强迫、敌对性、恐怖、偏执5个因子分与中国男性常模无显著性差异(P>0.05);患者最为担心的问题依次是担心疾病的预后、治疗是否有效、疾病对性功能影响、影响生育等。患者需求依次是改善化验指标、缓解症状、尊重隐私等。结论:慢性前列腺炎患者心理健康水平比普通人群要低,建立良好的护患关系,使患者正确了解关于前列腺炎的科普知识,养成良好的生活习惯能有效地减轻或解除患者的病痛。     

兰州市狱警心理卫生状况与影响因素分析

目的研究兰州市狱警人员的心理卫生状况与社会因素对其的影响。方法采用病例对照研究方法，调查组与对照组均接受一般情况问卷、症状自评量表、生活质量综合评定问卷、自我接蚋问卷等4个量表问卷的测查。结果（1）调查组的SCL-90各因子得分高于对照组（P羽，001）。（2）调查组自我接蚋因子得分低于对照组（P=0．001）。（3）调查组生活质量综合评定问卷得分低于对照组（P〈0．001）。（4）多因素回归分析SCL-90总因子得分相关因素主要为躯体症状严重程度、自我接蚋因子、躯体症状严重程度与SCL-90总因子得分呈负相关，自我接蚋因子得分与SCL-90总因子得分呈负相关。结论狱警人员较对照组心理健康状态有显著性差异，自我接蚋因子得分低于对照组，生活质量低于对照组。     

慢性湿疹患者心理健康状况及其对生活质量影响的临床研究

目的探讨心理因素对慢性湿疹（CE）患者生活质量的影响。方法收集200例CE患者（CE组）为研究对象,以同期健康体检者为对照组。应用症状自评量表（SCL-90）评价CE患者的心理健康状况;应用皮肤病生活质量指数（DLQI中文版）评价CE患者的生活质量,并用多元回归分析方法分析心理健康状况等因素对CE患者生活质量的影响。结果 CE组SCL-90总分、阳性项目数、阴性项目数、躯体化、抑郁、焦虑及第10因子等评分均明显高于正常对照组（均P〈0.01）;CE组的精神病性评分也高于对照组,差异均有统计学意义（均P〈0.05）;强迫、人际关系敏感、敌对、恐怖、偏执及阳性症状均分等两组比较,差异均无统计学意义（均P〉0.05）。CE组患者症状与情感、社会交际及治疗等6个方面得分均比对照组高,差异均有统计学意义（均P〈0.01）。多元逐步回归表明,影响DLQI总分的因素为病情、受教育程度、经济状况和SCL-90总分。结论 CE患者存在着严重的心理健康问题,且生活质量较差,SCL-90量表评价的心理健康状态也是影响CE患者生活质量的重要因素。     

慢性前列腺炎患者的心理影响因素及心理治疗的应用

目的分析心理因素对慢性前列腺炎患者的影响并探讨心理治疗在慢性前列腺炎治疗中的应用。方法采用心理卫生自评量表（SCL-90）对136例慢性前列腺炎患者的心理状况进行测评分析，并将其随机分成两组。对照组60例，仅应用抗生素及中成药等治疗；实验组76例，除应用上述综合性治疗外，还应用心理认知治疗。结果①136例慢性前列腺炎患者SCL-90总分平均值及阳性因子分高于我国常模（P〈0．01）；其中因子分1项阳性者107例（78．7％），因子分2项以上阳性者29例（21．3％）；②心理治疗组症状改善明显高于对照组，治愈率（P〈0．05）和有效率（P〈0．01）均高于对照组。结论慢性前列腺炎患者的心理因素是前列腺炎症状加重和难治的重要原因之一，对慢性前列腺炎患者辅以相应的心理治疗是行之有效的。     

慢性前列腺炎患者性功能障碍与社会功能状况

目的:分析研究慢性前列腺炎患者性功能障碍与社会功能状况。方法:采取我院2015年1月至2016年8月收治的400例慢性前列腺炎患者,将其分为研究组和对照组各200例。其中研究组患者患有慢性前列腺炎和性功能障碍,对照组患者只患有慢性前列腺炎;分析两组患者的SCL-90(90项症状自评量表)、HAS(汉密尔顿焦虑量表)评分和HDS(汉密尔顿抑郁量表)评分。结果:研究组的HAS和HDS评分均高于对照组,其差异具统计学意义(P0.05);研究组各项症状的SCL-90评分均大于对照组,其差异具统计学意义(P0.05)。结论:采取了解患者心理活动、对患者进行心理辅导等措施,可增强患者的心理素质,保护患者身心健康,提高患者慢性前列腺炎和性功能障碍的疗效。     

679名镇沅县苦聪人心理健康状况及生活质量随访

目的:了解苦聪人群的心理健康状况及生活质量两年后的变化.方法:用症状自评量表(SCL-90)及生活质量综合评定问卷-74(GQOLI-74)对普洱市镇沅县苦聪人聚居的和平、者东、三章田、九甲四乡679名苦聪族居民进行横断面调查,与2006年调查的684名的资料进行比较,并将SCL-90的统计结果与全国正常人常模比较.结果:两组受教育程度有显著性差异(P<0.01);研究组与对照组除人际关系和敌对因子外SCL-90总分和其他因子分均显著低于对照组; 研究组(GQOLI-74)各维度得分明显高于对照组,所有组间差异均达到统计学非常显著意义水平.结论:苦聪人的心理健康状况及生活质量均较两年前提高.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.