腹腔镜下全膀胱切除原位回肠新膀胱术(5例报告)

目的 探讨在基层医院采用腹腔镜下全膀胱切除原位回肠新膀胱术的临床应用.方法 浸润性膀胱癌患者5例,年龄60 ～ 65岁,男3例,女2例.采用OLYMPUS腹腔镜根治性切除膀胱后通过腹壁小切口形成回肠新膀胱,然后在腹腔镜下将新膀胱与尿道吻合.结果 5例患者手术均成功.手术平均时间8 h,出血量平均280 ml.术后2周拔除输尿管支架管,术后3周拔除导尿管.术后随访时间5 ～ 19个月,除1例女性患者外均能控制排尿,肾功能电解质大致在正常范围,未见肿瘤复发及远处转移.结论 腹腔镜下全膀胱切除原位回肠新膀胱术使传统的膀胱癌根治手术实现微创化,术中出血少,术后恢复快,在基层医院开展已成为可能.     

腹腔镜下全膀胱切除原位回肠新膀胱重建术(附5例报告)

目的:介绍腹腔镜下全膀胱切除原位回肠新膀胱重建术的经验。方法:采用腹腔镜下全膀胱切除原位回肠新膀胱重建术治疗浸润性膀胱癌患者5例。方法是经腹壁小切口取出切除物,行回肠去管成形新膀胱,然后在腹腔镜下将新膀胱与尿道连续吻合。结果:5例患者手术成功,手术时间4.5~7.2h。腹腔镜手术中以超声刀及双极电凝行膀胱侧韧带、前列腺血管蒂及前列腺尖部切断止血,未使用钛夹、术中出血量180~550ml,平均输血400ml。术后4~5天恢复饮食,3周拔除输尿管支架管,4周拔除尿管。患者白天可完全控制排尿,2例夜间偶有尿失禁。1例术后尿漏,经引流治愈。结论:腹腔镜下全膀胱切除术具有创伤小、出血少、恢复快等优点;而回肠新膀胱和尿道连续吻合具有操作方便、省时、缝合紧密、可防止尿漏等优点。     

机器人辅助全腹腔镜下膀胱根治性切除原位回肠新膀胱术的护理配合

目的:总结机器人辅助全腹腔镜下膀胱根治性切除原位回肠新膀胱术的手术护理配合.方法:回顾性分析2020年5月～2020年7月华中科技大学同济医学院附属同济医院收治的行机器人辅助全腹腔镜下膀胱根治性切除原位回肠新膀胱术膀胱肿瘤患者(8例)的关于手术护理配合的临床资料,总结分析术前访视、术前用物准备、手术设备布局管理、术中体位管理、术中洗手配合、术中体温管理及耗材管理等情况.结果:8例手术均顺利完成,无中转开放病例.手术时间为361(325～410)min,术中出血量为110～230ml,术后均无手术并发症,术后住院时间为9～13d,均顺利出院.结论:完善的手术配合流程、合理的机器设备布局、全面的围手术期护理,可有效确保机器人辅助全腹腔镜下膀胱根治性切除原位回肠新膀胱术顺利进行,促进手术患者快速康复.     

腹腔镜下膀胱根治性切除-原位回肠新膀胱术:附22例报告

目的探讨腹腔镜下膀胱根治性切除-原位回肠新膀胱术治疗肌层浸润性膀胱癌的手术疗效及并发症。方法回顾性分析惠州市中心人民医院自2005年10月至2013年10月开展腹腔镜下膀胱根治性切除-原位回肠新膀胱术患者的临床资料,22例确诊为浸润性膀胱癌患者,其中男18例,女4例,对手术时间、出血量及随访结果等进行分析。结果平均手术时间为6.5 h,平均出血量为362 ml,无中转开放手术,无围手术期死亡病例,所有患者手术切缘均为阴性。术后随访12~106个月,随访期间死亡7例,其中与肿瘤相关死亡5例。结论腹腔镜下膀胱根治性切除-原位回肠新膀胱术在具有腹腔镜技术的综合医院开展是可行的,其并发症较少及具有较好的新膀胱功能。     

腹腔镜保留前列腺尖部包膜根治性膀胱切除W形回肠新膀胱术尿控和勃起功能研究

目的探讨腹腔镜下保留前列腺尖部包膜根治性膀胱切除W形原位回肠新膀胱术的临床疗效。 方法回顾性分析2019年1月至2021年12月行腹腔镜根治性膀胱切除W形回肠原位新膀胱术的43例男性膀胱癌患者的临床资料。分为保留前列腺尖部包膜组20例（观察组）和非保留前列腺尖部包膜组23例（对照组）。观察组在距前列腺尖部1.0 cm处切开前列腺包膜,剜除前列腺,保留部分前列腺包膜的腹腔镜膀胱根治切除。对照组采用常规腹腔镜膀胱根治切除。两组W形回肠新膀胱制作方法相同。术后3周拔除导尿管,每３个月定期复查,收集所有患者的临床资料和完整随访信息。 结果所有患者均顺利完成手术。术后随访6~40个月无肿瘤复发。两组患者在术前人口学资料、膀胱肿瘤分期、手术时间、术中出血量、术中并发症、90 d内并发症发生率和术后6个月新膀胱残余尿量差异均无统计学意义（P>0.05）。术后6个月尿控率和勃起功能（IIEF-5评分）实验组优于对照组,日间尿控率分别为85.0%和52.2%（P<0.05）,夜间尿控率分别为65.0%和34.8%（P<0.05）,IIEF-5评分分别为[8（6,9）]分和[3（2,5）]分（P<0.05）。 结论腹腔镜下保留前列腺尖部包膜根治性膀胱切除W形原位回肠新膀胱术有利于尿控和勃起功能保护,不会影响肿瘤控制效果,值得临床推广应用。     

完全腹腔镜根治性膀胱切除术+邢氏原位回肠新膀胱的可行性和疗效

目的探讨完全腹腔镜根治性膀胱切除术+邢氏原位回肠新膀胱的可行性和术后临床效果。方法回顾性分析2013年7月至2019年8月41例行完全腹腔镜根治性膀胱切除术+邢氏原位回肠新膀胱患者的临床资料,其中北京朝阳医院31例,中国医学科学院肿瘤医院10例。年龄平均59(44~78)岁。体质指数平均25.3(20.1~34.7)kg/m^2。Charlson合并症指数评分平均3(2~6)分。术前检查均无尿道狭窄,无尿失禁。核素骨扫描、胸部X线片、B超等检查均未发现远处转移。所有患者行膀胱镜检查取活检或行经尿道膀胱肿瘤切除术,术前病理诊断:肌层浸润性膀胱癌30例(73.2%),非肌层浸润性膀胱癌9例(高危或反复复发)(22.0%),原位癌2例(4.9%)。41例均在全麻下先行腹腔镜根治性膀胱切除术+淋巴结清扫术,之后在体腔内采用邢式原位回肠新膀胱进行尿流改道。距回盲部约30 cm向近端截取末端回肠约60 cm,将已截取的回肠近端10 cm移至远端,作为右侧输入襻,之后将中间40 cm肠管去管化,U形缝合后反折缝合成球形,构建成顺蠕动双输入襻回肠新膀胱即邢式原位回肠新膀胱。记录围手术期相关资料、术后<30 d和30~90 d并发症情况、术后尿控恢复情况(日间、夜间控尿满意均定义为需要尿垫≤1个)及预后。比较手术开展的前21例和后20例患者手术时间、出血量的差异。结果本研究41例手术均顺利完成。总手术时间平均324.9(210~480)min。出血量平均177.6(50~700)ml。腹腔镜根治性膀胱切除术+淋巴结清扫术时间平均105.5(60~178)min,邢氏新膀胱构建时间平均179.7(121~298)min。前21例与后20例的总手术时间[(365.1±61.7)min与(290.9±41.8)min,P<0.01]、邢氏新膀胱构建时间[(211.7±44.5)min与(170.1±29.1)min,P=0.001]和出血量[(207.1±144.3)ml与(128.0±63.2)ml,P=0.001]比较差异均有统计学意义。术后病理诊断尿路上皮癌40例(2例合并原位癌),小细胞癌1例。清扫淋巴结数量中位值为19(11~58)枚。淋巴结阳性7例(17.1%)。切缘阳性3例(7.3%),分别为输尿管切缘阳性1例,膀胱切缘阳性2例。病理分期Ta^T1期16例,T2期10例,T3期13例,T4期2例。41例术后下地时间中位值为1(1~4)d,肠道功能恢复时间中位值为3(1~18)d,术后正常饮食恢复时间中位值为7(3~18)d,引流管留置时间中位值为9(3~23)d,输尿管支架拔除时间中位值为15(13~35)d,尿管拔除时间中位值为20(6~30)d,总住院时间中位值为21(11~35)d,术后住院时间中位值为14(7~29)d。术后1例进入ICU病房。术后<30 d Clavien 1~2级并发症19例(46.3%),分别为低白蛋白血症15例、感染2例、低钾血症1例、不全肠梗阻1例,对症处理后均好转;Clavien 3~4级并发症1例(2.4%),为空肠穿孔行手术治疗治愈。术后30~90 d Clavien 1~2级并发症2例(4.9%),分别为切口感染和低白蛋白血症各1例,对症处理后好转,无Clavien 3~4级并发症。术后随访时间平均17.6(2~64)个月。36例(87.8%)生存,其中2例(4.9%)转移,1例(2.4%)复发;5例(12.2%)死亡,死亡原因分别为骨转移1例、多发转移2例,心脏疾病2例。术后12个月复查血肌酐平均77.2(54.3~104.1)μmol/L;影像学检查40例无肾积水,1例出现肾积水。41例拔除尿管后均能自行排尿,无需导尿,术后12个月37例(90.2%)日间控尿满意,29例(70.7%)夜间控尿满意。结论完全腹腔镜根治性膀胱切除术+邢氏原位回肠新膀胱的构建方法简单,术后并发症少,尿控恢复较满意。     

腹腔镜下膀胱全切术治疗膀胱癌4例报告

目的:探讨腹腔镜下膀胱全切术治疗膀胱癌的可行性.方法:应用腹腔镜技术对4例膀胱癌患者进行膀胱全切术及原位回肠新膀胱手术.结果:4例患者膀胱根治均切除成功,手术时间220～270 min.腹腔镜下失血量400～500 ml.原位新膀胱手术时间200～270 min,输浓缩红细胞2个单位.术后3天恢复肠蠕动并拔除耻骨后引流管,4天开始进食.2周后拔除输尿管支架管.随访4～16个月,1例有排尿困难,1例轻微尿失禁,另2例排尿正常.4例均无复发.结论:腹腔镜膀胱全切术及原位回肠新膀胱手术创伤小,并发症少,出血少,有一定的优点,值得推广.     

腹腔镜下全膀胱切除原位回肠新膀胱术(附16例报告)

目的探讨在基层医院采用腹腔镜下全膀胱切除原位回肠新膀胱术的临床应用。方法对15例浸润性膀胱尿路上皮细胞癌Ⅱ～Ⅲ级、1例鳞状细胞癌患者行腹腔镜下全膀胱切除加原位回肠代膀胱术,观察手术时间、术中出血量、术后肠道功能恢复情况及术后并发症等手术效果。结果 16例患者膀胱根治均切除成功,手术时间240～320min。腹腔镜下失血量为100～500ml,平均为230ml。2例输浓缩红细胞2个单位。术后3d恢复肠蠕动并拔除耻骨后引流管,4d后开始进食。2周后拔除输尿管支架管。随访4～26个月,1例有排尿困难,5例术后早期出现轻微尿失禁,所有病例术后3个月均可完全控制排尿,5例男性患者有勃起功能障碍。16例均无复发。结论该术式具有微创、出血少、恢复快等特点,将成为治疗浸润性膀胱癌的安全、有效的方法之一,有可能在具有一定腹腔镜手术操作基础的基层医院逐步开展。     

腹腔镜膀胱根治性切除原位回肠新膀胱的随访疗效观察

目的随访探讨腹腔镜膀胱根治性切除原位回肠新膀胱术的疗效。方法 61例行腹腔镜膀胱根治性切除原位回肠新膀胱术的膀胱癌患者,随访1~24个月,每月定期门诊复查、电话等方式详细记录术后自主排尿情况等资料。结果所有患者均未见肿瘤复发。42例患者于拔除尿管后28~35d自控通畅排尿,每次尿量约180~410mL,每次间隔60~180min;13例患者出院后仍有不同程度日间尿失禁现象,6例有夜间尿失禁现象;3例术前性功能正常男性患者出现勃起功能障碍;彩超及静脉肾盂造影检查发现4例单侧肾积水,2例双肾积水。结论腹腔镜膀胱根治性切除原位回肠新膀胱术肿瘤控制好,患者术后可具有较好的控尿功能和较低的尿失禁发生率,部分有效保存性功能,能够有效确保患者的生活质量。     

腹腔镜下根治性全膀胱切除术加尿液改道治疗浸润性膀胱癌15例

【摘要】〓目的〓总结腹腔镜下全膀胱切除的经验。方法〓2010年8月至2015年1月治疗浸润性膀胱癌15例,男性13例,女性2例,年龄61~79岁,平均68岁。术前临床诊断:T2N0M0~ T3N0M0。腹腔镜下行盆腔淋巴结清扫,全膀胱切除,前列腺切除或子宫全切除、阴道壁部分切除。尿流改道方式:原位回肠新膀胱术4例;回肠通道术9例;输尿管皮肤造口术2例。结果〓15例手术成功,手术时间220~550 min(平均400 min)。出血量100~800 mL(平均240 mL);术中、术后输浓缩红细胞0~400 mL(平均200 mL)。术后3~8 d恢复饮食,3周拔除输尿管支架管,原位膀胱术者4周拔除尿管。随访1~40个月,无严重并发症发生。结论〓腹腔镜下根治性全膀胱切除术创伤小、出血少、术中操作精细、盆腔淋巴结清扫彻底、术后恢复快,可作为全膀胱切除手术的首选方法。     

LAPAROSCOPIC INTRACORPOREALLY CONSTRUCTED ILEAL CONDUIT AFTER PORCINE CYSTOPROSTATECTOMY

PURPOSE: We present our technique of laparoscopic ileal conduit creation after cystoprostatectomy in a porcine model performed in a completely intracorporeal manner. METHODS AND METHODS: After developing the technique in 5 acute animals laparoscopic cystoprostatectomy with intracorporeally performed ileal conduit urinary diversion was performed in 10 surviving male pigs. A 5-port transperitoneal technique was used. All steps of the technique applied during open surgery were duplicated intracorporeally. Specifically cystectomy, isolation of an ileal conduit, restoration of bowel continuity and mucosa-to-mucosa stented bilateral ileoureteral anastomosis formation were performed by exclusively intracorporeal laparoscopic techniques. RESULTS: Surgery was successful in all 10 study animals without intraoperative or immediate postoperative complications. Blood loss was minimal and average operative time was 200 minutes. Stenosis of the end ileal stoma specifically at the skin level was noted in 6 animals. Three deaths occurred 2 to 3 weeks postoperatively. At sacrifice renal function was normal in all surviving animals. No ileo-ureteral anastomotic strictures were noted on pre-sacrifice radiography of the loop or at autopsy examination of the anastomotic sites. CONCLUSIONS: Laparoscopic ileal conduit urinary diversion after cystoprostatectomy may be performed completely intracorporeally in the porcine model. Clinical application of this technique is imminent.     

Laparoscopic radical cystectomy with intracorporeal ileal conduit diversion: five cases with a 2-year follow-up

OBJECTIVE: To assess the feasibility and intermediate-term outcome of laparoscopic radical cystectomy (LRC) with ileal conduit urinary diversion in patients with organ-confined muscle-invasive carcinoma of the urinary bladder, the entire procedure undertaken intracorporeally only using laparoscopic techniques. PATIENTS AND METHODS: Five patients (four men and one woman) underwent LRC with intracorporeal ileal conduit diversion in February 2000, using a six-port transperitoneal technique. LRC, ileal conduit exclusion, restoration of ileo-ileal continuity, and bilateral stented uretero-ileal anastomoses were completed intracorporeally in all patients. The follow-up data up to 2 years are reported. RESULTS: All procedures were completed laparoscopically with no open conversion or intraoperative complications. The mean duration of surgery was 7.5 h; the blood loss was 360 mL and no patient required perioperative blood transfusion. The mean (range) hospital stay was 7 (6-22) days; the specimen weight was 225-400 g. The surgical margins of the bladder specimen were negative in each patient. One patient developed intestinal obstruction after surgery, requiring a diverting ileostomy for 12 weeks. At a follow-up of 2 years, two patients died, both from unrelated causes (myocardial infarction and septicaemia from pulmonary infection in one each). The three surviving patients are asymptomatic with normal upper tracts and no evidence of local recurrence or metastatic disease. CONCLUSION: LRC with ileal conduit diversion undertaken completely intracorporeally is a feasible option for muscle-invasive organ-confined carcinoma of the urinary bladder, with good outcomes over a 2-year follow-up.     

Does body mass index impact the performance of robot-assisted intracorporeal ileal conduit?

BACKGROUND AND PURPOSE: Body mass index (BMI) has been shown to influence perioperative outcomes for patients undergoing open radical cystectomy and urinary diversion. The impact of BMI on robot-assisted intracorporeal ileal conduit has not been studied. PATIENTS AND METHODS: All patients undergoing robot-assisted radical cystectomy (RARC) with ileal conduit at our institution were offered intracorporeal ileal conduit beginning May 2009. Fifty-six consecutive patients underwent robot-assisted radical cystectomy with intracorporeal ileal conduit from May of 2009 to July 2010. Patients were categorized into three groups based on BMI: Normal (BMI < 25 kg/m(2)), overweight (BMI=25-29 kg/m(2)), and obese (BMI ≥ 30 kg/m(2)). The effect of BMI on intraoperative and postoperative outcomes was assessed by retrospective review of a comprehensive RARC quality assurance database. Results: Median age at cystectomy was 72 (range 42-87 y), and 75% of patients were male. Median follow-up for the entire cohort was 5 months (range 12 d-16 mos). Median BMI was 27 kg/m(2) (range 19-47 kg/m(2)), and 75% of patients were overweight or obese. Age, ASA score, and overall operative time were not significantly different among the normal, overweight, and obese patients. Median urinary diversion times were 95, 151, and 124 minutes for normal, overweight, and obese patients, respectively (P=0.13). Conclusions: Robot-assisted intracorporeal ileal conduit can be safely performed in all body mass indices. Further studies are needed to assess long-term conduit function and stomal complications.     

Laparoscopic radical cystectomy with urinary diversion: completely intracorporeal technique

Laparoscopic radical cystectomy with urinary diversion performed using intracorporeal techniques exclusively is a new development in the growing field of minimally invasive urology. This report details step by step the completely intracorporeal laparoscopic technique of cystectomy, bilateral pelvic lymphadenectomy, and urinary diversion with creation of an ileal conduit or neobladder, including the isolation of ileum, restoration of bowel continuity, retroperitoneal transfer of the left ureter to the right side, bilateral stented ureteroileal anastomoses, and urethroileal anastomosis in case of orthotopic diversion. Although at present, this is still a technique in development at high-volume medical centers, it holds promise as a minimally invasive yet appropriately radical form of treatment for patients with muscle-invasive bladder cancer. Definition of its true role awaits greater experience and long-term comparisons of the outcomes with those of traditional open surgery.     

Laparoscopic radical cystectomy with ileal conduit urinary diversion

OBJECTIVE: To report on the surgical technique of laparoscopic radical cystoprostatectomy with ileal conduit urinary diversion. METHODS: A 79 years old man with histologically proven transitional cell carcinoma of the bladder stageT 2b NxMx underwent a laparoscopic radical cystoprostatectomy with ileal conduit urinary diversion. The cystoprostatectomy was performed with laparoscopic technique. Creation of the ileal conduit and the stoma were performed through a mini-laparotomy. Specific technical aspects are described. RESULTS: The procedure was completed laparoscopically. The creation of the ileal conduit and stoma were performed through a mini-laparotomy. The surgical margins were free of disease. There were no intra or postoperative complications. The operative time was 290 min. Estimated blood loss was 380 mL. Hospital stay was 6 days. At 3 months there is no evidence of disease. The patient resumed his normal activity. CONCLUSION: Laparoscopic radical cystoprostatectomy with ileal conduit urinary diversion is a feasible option for organ-confined carcinoma of the bladder. The procedure is technically demanding and should be performed in centers with large experience in laparoscopic surgery.     

Robotic Intracorporeal Orthotopic Ileal Neobladder: Replicating Open Surgical Principles

Background

Robotic radical cystectomy (RC) for cancer is beginning to gain wider acceptance. Yet, the concomitant urinary diversion is typically performed extracorporeally at most centers, primarily because intracorporeal diversion is perceived as technically complex and arduous. Previous reports on robotic, intracorporeal, orthotopic neobladder may not have fully replicated established open principles of reservoir configuration, leading to concerns about long-term functional outcomes.

Objective

To illustrate step-by-step our technique for robotic, intracorporeal, orthotopic, ileal neobladder, urinary diversion with strict adherence to open surgical tenets.

Design, setting, and participants

From July 2010 to May 2012, 24 patients underwent robotic intracorporeal neobladder at a single tertiary cancer center. This report presents data on patients with a minimum of 3-mo follow-up (n = 8).

Surgical procedure

We performed robotic RC, extended lymphadenectomy to the inferior mesenteric artery, and complete intracorporeal diversion. Our surgical technique is demonstrated in the accompanying video.

Outcome measurements and statistical analysis

Baseline demographics, pathology data, 90-d complications, and functional outcomes were assessed and compared with patients undergoing intracorporeal ileal conduit diversion (n = 7).

Results and limitations

Robotic intracorporeal urinary diversion was successfully performed in 15 patients (neobladder: 8 patients, ileal conduit: 7 patients) with a minimum 90-d follow-up. Median age and body mass index were 68 yr and 27 kg/m², respectively. In the neobladder cohort, median estimated blood loss was 225 ml (range: 100–700 ml), median time to regular diet was 5 d (range: 4–10 d), median hospital stay was 8 d (range: 5–27 d), and 30- and 90-d complications were Clavien grade 1–2 (n = 5 and 0), Clavien grade 3–5 (n = 2 and 1), respectively. This study is limited by small sample size and short follow-up period.

Conclusions

An intracorporeal technique of robot-assisted orthotopic neobladder and ileal conduit is presented, wherein established open principles are diligently preserved. This step-wise approach is demonstrated to help shorten the learning curve of other surgeons contemplating robotic intracorporeal urinary diversion.     

腹腔镜膀胱全切回肠膀胱术后早期肠梗阻的病因及治疗

目的:探讨腹腔镜膀胱全切回肠膀胱术后并发早期肠梗阻的病因及治疗方法。方法:回顾性分析2010年9月~2013年6月因腹腔镜膀胱全切回肠膀胱术后并发早期肠梗阻的19例患者的临床资料:均发生于术后1个月内,其中炎性肠梗阻12例,麻痹性肠梗阻4例,粘连性肠梗阻2例,肠内疝1例,发生率为12.8%,且发生于开展腹腔镜膀胱全切回肠膀胱术的早期。除1例肠内疝手术解除外,其余患者均经保守治疗。结果:19例肠梗阻患者均治愈出院。结论:肠梗阻是腹腔镜膀胱全切回肠膀胱术较为常见的并发症,术后并发肠梗阻的病因复杂,以保守治疗为主,少数保守治疗无效者需及时中转手术治疗。     

体外协助尿流改道的腹腔镜全膀胱根治性切除术

目的 探讨体外协助尿流改道的腹腔镜全膀胱根治性切除术的疗效.方法 2006年6月～2012年6月施行体外协助尿流改道的腹腔镜全膀胱根治性切除术28例,全膀胱切除和盆腔淋巴结清扫均在腹腔镜下完成,标本自下腹部小切口取出,体外协助尿流改道采用回肠膀胱术（Bricker手术）和原位回肠新膀胱2种术式,其中Bricker手术22例、原位回肠新膀胱术6例.结果 均一次手术成功,腹腔镜盆腔淋巴结清除及全膀胱切除手术时间150～240 min,平均180 min;体外协助尿流改道时间90～270 min,平均150 min;术中出血200 ～900 ml,平均350 ml;肠功能恢复时间3～4d.6例原位回肠新膀胱2～4周拔除导尿管,能正常排尿,无尿潴留和肾功能损害发生.26例随访6～36个月,平均15个月,1例术后23个月死于复发及远处广泛转移,2例死于其他内科疾病,其余患者一般情况良好,未见肿瘤复发及转移.结论 体外协助尿流改道的腹腔镜全膀胱根治性切除术疗效满意.     

腹腔镜下根治性膀胱切除回肠新膀胱术（附15例报告）

目的介绍腹腔镜下根治性膀胱切除回肠新膀胱术的方法及经验。方法本组15例，均为男性，年龄45～62岁，平均54岁。术前均明确诊断为浸润性膀胱癌。采用腹腔镜下行膀胱癌根治性切除，然后取长约40cm回肠于体外缝制贮尿囊及输尿管贮尿囊吻合，体内行贮尿囊尿道吻合术。结果手术时间5．5～8h，平均6．5h；出血量200～1100ml，平均550ml。术后8周静脉尿路造影以及代膀胱造影检查显示：双肾显影良好，无输尿管返流及梗阻，代膀胱充盈良好，容量约300ml。术后3个月全部患者日间控尿良好，7例患者夜间控尿良好，夜间排尿2～3次。结论腹腔镜下膀胱全切除、体外建成贮尿囊及输尿管再植、体内贮尿囊尿道吻合术创伤小、出血少、术后尿控率高、恢复快。