NRD辅助Ilizarov技术治疗胫骨感染性骨与软组织缺损

目的:探讨NRD辅助Ilizarov技术治疗胫骨感染性骨与软组织缺损的临床疗效。方法:选取2013年3月至2020年12月治疗的胫骨感染性骨与软组织缺损患者48例,男34例,女14例,年龄24~55(40.54±11.64)岁,分为研究组与对照组。研究组患者25例,男17例,女8例,年龄31~55(41.36±9.69)岁,采用NRD辅助Ilizarov骨搬移技术治疗。对照组23例患者,男17例,女6例,年龄24~53(38.61±8.76)岁,采用传统骨搬移技术治疗。通过两组患者的治愈率、复发率、针道感染发生率、抗生素使用时间、创面愈合时间、外固定携带时间、骨搬移时间、骨愈合情况、术后功能等指标评价治疗效果。结果:随访时间12~62(33.0±7.2)个月,末次随访时,两组患者的治愈率比较,差异无统计学意义(P>0.05),研究组复发率低于对照组(P<0.05),针道感染发生率低于对照组(P<0.05)。研究组的抗生素使用时间、创面愈合时间均少于对照组(P<0.05),两组之间的骨搬移时间、外固定携带时间差异无统计学意义(P>0.05),两组骨愈合情况、术后功能差异无统计学意义(P>0.05)。结论:NRD辅助Ilizarov技术治疗胫骨感染性骨与软组织缺损,可以达到满意的治疗效果,缩短了治疗周期及抗生素使用时间。     

一期延长与加压外固定治疗胫骨复杂性骨不连及骨缺损

下肢严重创伤所造成的胫骨骨感染、骨不连、骨缺损,常伴有复杂的软组织损伤,治疗较为棘手.传统的治疗方法多采用植骨加内固定,如伴随有大段骨缺损或伴有肢体短缩,则缺损组织的修复及功能重建将很困难.自1994年1月～2004年2月,应用Ilizarov技术一期延长与加压外固定治疗复杂性胫骨缺损8例,取得较满意的疗效,现报告如下。     

Ilizarov 外固定器治疗胫骨骨不连

目的 探索应用llizarov外固定器治疗胫骨骨不连的方法。方法 对16例病人依据骨不连的不同种类，采用不同种植骨术外用Ilizarov外固定器固定，外固定时间为4～9个月，平均6个月。结果 术后4～6周拍X光片检查均可见明显骨痂生长，随访1～4a，效果良好。结论 llizarov外固定器在治疗胫骨不连接中显示出适应性广泛，固定牢固，符合生物力学原则，骨痂生长迅速，早期离床活动，有利于关节活动等优点，该方法是治疗胫骨骨不连较为理想的方法之一，值得推广应用。     

Ilizarov骨延长和骨搬移技术治疗下肢长骨创伤后慢性骨髓炎

目的探讨Ilizarov骨延长和骨搬移技术治疗下肢长骨创伤后慢性骨髓炎的效果。方法采用Ilizarov骨延长和骨搬移技术治疗10例下肢长骨创伤后慢性骨髓炎患者。结果患者均获得随访,时间2～28个月。9例手术感染得到一期控制,1例术后进行1次清创术后感染得到控制。骨折愈合、延长停止后,8例患肢长度比对侧缩短2. 5 cm,2例患肢长度比对侧缩短2. 5 cm和3. 0 cm。结论 Ilizarov骨延长和骨搬移技术治疗下肢长骨创伤后慢性骨髓炎在控制感染和改善患肢功能方面有一定的优越性。     

Ilizarov外固定器治疗胫骨Cierny Ⅳ型感染性骨不连的临床疗效

目的探讨Ilizarov外固定骨牵移技术治疗胫骨CiernyⅣ型感染性骨不连的临床疗效。方法采用Il-izarov外固定骨迁移技术治疗35例胫骨感性骨不连患者。结果手术时间58～80(64±4.2)min。35例均获随访,时间14～33(19.6±6.2)个月。骨牵移长度4～10(5±2.2)cm,牵移骨痂矿化的时间为11～20(12.1±3.2)周,牵移骨段与胫骨截骨段接触后骨折愈合时间为13～26(15.9±1.3)周。3例出现马蹄足畸形,给予跟腱延长;2例出现骨不连,断端清理髂骨植骨后愈合;1例出现钉道热力性骨坏死,清创后治愈。疗效评定按Johner-Wruh评定:优22例,良8例,差5例,优良率达85.7%。结论 Ilizarov外固定骨牵移技术治疗胫骨感染性骨不连临床疗效满意。     

Ilizarov技术治疗胫骨干感染性骨不连

目的探讨应用Ilizarov技术治疗胫骨干感染性骨不连的临床效果。方法对22例骨创伤后胫骨感染性骨不连患者采取大段病灶切除+旷置并相应的干骺端截骨术。术后10 d以0.25 mm/6 h速度延长,经8～25周固定延长至骨缺损端会师,于骨缺损处两断端加压并继续维持外固定支架至骨愈合。结果 22例均获随访,时间12～24个月。骨延长6～18(9.5±4.5)cm,骨性感染全部治愈。带支架时间6.5～13个月。19例加压固定处及延长部位骨生长良好,达到了骨性愈合;3例断端骨接触后6个月无明显骨愈合,2例行自体髂骨植骨、1例拆除支架后行自体髂骨植骨内固定,4～6个月达到骨性愈合。截骨延长区及骨缺损对合处对位对线良好。结论 Ilizarov技术治疗胫骨感染性骨不连,术后感染控制良好,骨愈合率高。     

外固定架治疗慢性骨髓炎性骨不愈合

感染性骨髓炎致骨不愈合是骨科临床上一种常见性疾病，也是一种难治性疾病。如何尽快彻底控制感染，促进骨愈合一直是临床医生关注的问题。从1995年-2002年，共收治39例此类患者，通过病灶刮除、植骨、闭合创面、外固定架固定，取得了满意疗效，现报告如下。     

Ilizarov技术治疗胫骨慢性骨髓炎骨不连12例

[目的]探讨Ilizarov牵拉成骨技术治疗胫骨慢性骨髓炎的方法及疗效。[方法]遵照Ilizarov牵拉组织再生原理,应用Ilizarov环形外固定架固定,采取病灶清除,Ilizarov环架旋钮缓慢牵拉,使牵拉成骨,治愈骨髓炎。[结果]12例患者经随访全部治愈,延长最长达23 cm,最短的6 cm,平均15 cm,延长时间3个月¹年,平均7个月,拆架时间10个月1年,平均7个月,拆架时间10个月²年,平均16个月,无1例并发感染及其他并发症。[结论]应用Ilizarov环形外固定架治疗慢性骨髓炎是目前最安全、有效的治疗方法,具有创伤小、并发症少、费用低、痛苦小、不易复发等优点,疗效确切。     

应用Ilizarov技术修复胫骨慢性骨髓炎并骨缺损

目的探讨应用Ilizarov技术治疗胫骨创伤后慢性骨髓炎并感染性骨缺损的临床疗效。方法对8例胫骨创伤后慢性骨髓炎并感染性骨缺损行清创、可延长外固定架固定、干骺端截骨及中间骨段逐步搬运。结果 8例均获随访6～40个月,平均31.5个月。骨与皮肤缺损得到修复,患侧肢体长度与健侧无明显短缩。结论应用Ilizarov技术治疗难治性胫骨骨髓炎合并骨缺损或皮肤软组织缺损创伤小,能够避免多次复杂手术,可简化治疗过程,疗效肯定。     

Outcomes of post-traumatic tibial osteomyelitis treated with an Orthofix LRS versus an Ilizarov external fixator

ObjectiveTo compare the therapeutic effects of the Orthofix limb reconstruction system (LRS) versus the Ilizarov external fixator on osteomyelitis of a tibial bone defect.Materials and methodsAmong 153 patients hospitalized for bone lengthening therapy from January 1, 1996 to January 1, 2015, 129 patients were selected for a retrospective analysis. Forty-three of the candidate patients were treated using the Orthofix LRS and the other 86 were treated using an Ilizarov external fixator. The average follow-up was 96 months. We evaluated the patients at follow-up visits, and compared the length of time the patients wore the fixation devices. We also examined the scores of Activities of Daily Living (ADL) tests and a Self-rated Anxiety Scale (SAS), the range of motion, and the incidence of pin track infections.ResultsThe results indicated that both approaches were effective for treating the bone defect. Compared with the patients who wore an Ilizarov fixator for the treatment of post-traumatic osteomyelitis, those who wore an Orthofix LRS tended to be more satisfied with their quality of life and the outcome after the operation.ConclusionAlthough both approaches were effective for treating the bone defect, the overall patient outcomes were superior for the Orthofix LRS, suggesting that it should be considered as the first option in the treatment of traumatic osteomyelitis of the tibial diaphysis.     

骨搬运与LCP结合植骨内固定治疗下肢感染性骨不连的比较

目的比较Ilizarov骨搬运技术与锁定加压接骨板(LCP)结合植骨内固定治疗下肢感染性骨不连的临床疗效。方法回顾性分析自2010-07—2015-04诊治的感染性骨不连22例,首先给予清创、VSD负压吸引及抗生素链珠置入控制感染,待感染控制良好后,进行Ilizarov骨搬运技术(骨搬运组11例)或LCP结合植骨内固定(LCP组11例)治疗。比较2组术中失血量、手术次数、感染控制率、住院时间、术后至开始部分负重时间及末次随访时AAOS评分。结果所有患者均获得随访3~35个月,平均24.2个月。末次随访时骨搬运组4例完全愈合恢复,7例感染消除,骨搬运已结束,处于骨愈合期;1例发生针道感染,常规换药加抗生素治愈。LCP组8例已完全恢复,3例出现感染,再次行手术治疗。与LCP组比较,骨搬运组术中失血量及手术次数较少,感染控制率更高,差异有统计学意义(P0.05)。2组住院时间、术后至开始部分负重时间、AAOS评分比较差异无统计学意义(P0.05)。结论 Ilizarov骨搬运技术治疗下肢感染性骨不连的感染控制率高,且能够有效保护软组织,促进其恢复,为肢体恢复长度提供保障。     

Results of vancomycin-impregnated cancellous bone grafting for infected tibial nonunion

Introduction Bone grafting plays a critical role in promoting bone healing in infected nonunion, although recurrent infection is of concern. Cancellous bone grafting as an antibiotic delivery system has been reported as an effective method to combat infections. In this study, we report the clinical results of vancomycin-impregnated cancellous bone grafting for the treatment of infected tibial nonunion.Materials and methods Between January 1996 and March 2001, 18 patients with infected tibial nonunion treated with vancomycin-impregnated cancellous bone grafting were available for follow-up. According to the Cierny-Mader classification, all patients belonged to type IVA and IVB osteomyelitis. Adequate debridement, stabilization with external fixation, and staged vancomycin-impregnated cancellous bone grafting were used in all patients. Regular clinical and radiographic follow-ups were conducted.Results Infection control was obtained in all 18 patients with a 100% infection arrest rate. Bone union was achieved in 13 of 18 patients at an average of 5.8 months. Bone union was obtained subsequently in the remaining five patients after closed nailing in four, and plating and bone grafting in one patient. Radiographs showed good consolidation and hypertrophy of grafted bone at an average follow-up of 48 months.Conclusion We conclude that vancomycin-impregnated cancellous bone grafting is a safe method for the treatment of infected tibial nonunion.     

The treatment of infected nonunion of the tibia following intramedullary nailing by the Ilizarov method

The purpose of this study was to demonstrate the effectiveness of the Ilizarov method and circular external fixator in order to eradicate the infection and restore bone union, limb anatomy and functionality in cases with infected nonunion of the tibia following intramedullary nailing.During 7 years nine patients suffering from infected nonunion of the tibia after intramedullary nailing were treated in our department. The series comprised seven men and two women with an average age of 39.7 years (range 21-75 years). The patients had previously undergone an average of 4.8 operations (range 3-6 operations). Active purulent bone infection occurred in all nine patients. Bone defect was present in all patients with a mean size of 5 cm (range 2-12 cm). In three cases with bone defect less than 2 cm, monofocal compression osteosynthesis technique was used. In the rest cases where bone defect exceeded 2 cm, bifocal consecutive distraction-compression osteosynthesis technique was applied. Three patients required a local gastrocnemius flap. The mean follow-up period was 26.6 months (range 13-42 months). Results were evaluated using Paley's functional and radiological scoring system.Bone union was achieved in all nine patients without recurrence of infection during the follow-up period. Bone results were graded as excellent in five cases and good in the rest four cases. Functional results were graded as excellent in three cases, good in four and fare in two cases. Mean external fixation time was 187.4 days (range 89-412 days) and mean lengthening index was 32 days/cm (range 27-39 days/cm). Complications observed included eight grade II pin tract infections, axial deformity at the lengthening site in two cases and at the nonunion site in another two cases. Ankle joint stiffness was detected in five cases.The Ilizarov method may be an effective method in infected nonunions of the tibia following intramedullary nailing.     

抗生素骨水泥间置器治疗髓内固定术后骨髓炎合并骨不连

目的探讨抗生素骨水泥间置器治疗髓内固定术后骨髓炎合并骨不连的临床疗效。方法 2002年6月-2006年5月,收治12例行切开复位交锁髓内钉内固定术后骨髓炎合并骨不连患者。男8例,女4例;年龄26～53岁,平均40.2岁。骨折部位:胫骨7例,股骨5例。髓内固定术后2周内感染7例,3个月内感染5例。患者于感染发生后1～24个月入院,平均5个月。细菌培养10例呈阳性,2例呈阴性。白细胞计数、红细胞沉降率、高敏C反应蛋白均高于正常值。一期手术取出内固定物,髓内插入抗生素骨水泥间置器临时固定;3～6个月待感染控制后,二期手术取出间置器,行自体髂骨植骨锁定钢板内固定术。结果患者两期手术切口均Ⅰ期愈合,无早期相关并发症发生。二期术后患者均获随访,随访时间24～48个月,平均34个月。二期术后3个月红细胞沉降率、白细胞计数以及高敏C反应蛋白均正常。X线片复查,骨折均在二期术后10～14周达临床愈合,平均12周。除1例患者膝关节屈曲约90°外,其余患者下肢功能均恢复正常。随访期间均无感染复发。结论采用抗生素骨水泥间置器临时固定可以有效控制感染,待感染控制后二期手术取出间置器行植骨内固定,是治疗髓内固定术后骨髓炎合并骨不连的有效方法之一。     

混合式单臂外固定架骨延长术治疗感染性骨不连

目的评价混合式单臂外固定架骨延长术治疗长骨干骺端感染性骨不连的初步临床结果。方法2003年1月至2006年2月采用混合式单臂外固定架固定、局部清创和截骨延长法治疗感染性骨不连21例,男17例,女4例;年龄18～48岁,平均31.5岁。16例为开放骨折内固定术后感染,5例为闭合骨折内固定术后感染。胫骨近端12例,胫骨远端6例,股骨远端3例。12例行骨折端植骨,其中2例二次植骨。结果21例术后随访10～36个月,平均18个月。18例骨折获得初期愈合,3例骨折愈合时仍有局部窦道和渗液,2例骨折尚未完全愈合,1例行截肢术,20例感染得到控制。改良ASAMI骨评定结果为优良13例,中4例,差4例;功能评定结果为优良11例,中6例,差4例。平均骨延长5.6cm,平均愈合时间为11个月。15例发生钉道感染。结论对长骨干骺端感染性骨不连可使用混合式单臂外固定架骨延长术、骨折端开放换药的方法。该方法控制感染好,可自体修复骨缺损,供区畸形发生率低。但固定需采用HA涂层螺钉,严格控制延长速度,一般在1mm/d以内,分次进行延长,手术风险小。     

自体红骨髓注射治疗骨不连术后局灶性骨缺损

目的：观察自体红骨髓注射治疗骨不连术后局灶性骨缺损的临床疗效。方法：13例骨不连术后局灶性骨缺损患者,男8例,女5例;年龄15-60岁,平均32．5岁。骨缺损部位：胫骨7例,股骨2例,肱骨4例。采用自体红骨髓注射至骨折断端治疗,自体红骨髓经皮注射每2周1次,共5次,每月复查肢体正侧位X线片。结果：13例全部获得随访,时间6～12个月,平均7．5个月。13例骨缺损完全修复,平均愈合时间4个月。无严重并发症发生。结论：自体红骨髓注射创伤小,疗效明确,并能缩短骨缺损修复时间,有利于促进肢体功能恢复,是治疗骨不连术后局灶性骨缺损的一种好方法。     

Periarticular large bone defects treatment with ring external fixator

BackgroundJoint stiffness and limited bone stock for fixation were the main problems in management of periarticular bone defects. The present study aimed to report clinical and radiographic outcome of periarticular, large (≥8 cm) bone defects treated with ring external fixator.Materials and methodsSeventeen patients (10 males and 7 females) who had periarticular bone loss at the minimum of 8 cm were treated with ring external fixator. Acute shortening and subsequent lengthening at the corticotomy site were performed in 5 patients. Bone transport was performed in 12 patients. Clinical outcome and radiographic outcome were reviewed.ResultsSeventeen patients (10 males and 7 females). Mean age was 31.1 years (9–52 years). Mean bone gap was 9.17 cm (8–14 cm.). Mean follow-up period was 39.7 months (30–60 months). Fracture united primarily in 14 cases and after iliac bone graft in 2 cases. One patient had nonunion. Based on ASAMI evaluation;The bone result was excellent, good, and poor in 13, 3, and 1 patients, respectively. The functional results were excellent and good in 14 and 3 patients respectively. Ten patients had superficial pin tract infection.ConclusionPeriarticular large bone defects were successfully treated with ring external fixator by bone transport or acute shortening and subsequent lengthening at corticotomy site. Superficial pin tract infection and joint stiffness were common problems in management of periarticular large bone defects. Early convert to internal fixation after achieve the acceptable length or after successfully bony contact of bone transport fragment to allowed early motion of the joint was recommend. Good to excellent functional outcomes were achieve in majority of the patients.     

病变切除外固定支架固定及膜诱导技术治疗胫骨骨折术后骨髓炎

目的 :研究病变切除外固定支架固定结合膜诱导技术治疗胫骨骨髓炎的临床疗效。方法 :自2011年6月至2014年6月手术治疗13例胫骨骨髓炎患者,其中男8例,女5例;年龄16~67岁,平均(37.3±14.3)岁。Ⅰ期病变切除,抗生素骨水泥植入,外固定支架固定,6~8周诱导膜形成后Ⅱ期手术取出骨水泥,植骨并利用膜诱导技术修复骨缺损促进骨质愈合。结果:随访24~52个月,13例感染无复发,骨质均获愈合,功能恢复良好。结论:采用病变切除外固定架固定及膜诱导技术治疗胫骨骨折术后骨髓炎可以取得很好的治疗效果。