光动力治疗鲜红斑痣疗效与安全性的meta分析

目的 评价光动力治疗鲜红斑痣相较于金标准脉冲染料激光的疗效和安全性.方法 检索PubMed、CENTRAL、Embase、Web of Science、中国知网、维普、万方数据库关于光动力治疗、脉冲染料激光、鲜红斑痣的临床随机对照研究,检索时间限定为建库至2021年4月3日,结局指标包括有效率、不良反应发生率.提取数据...     

中医中药联合强脉冲光治疗面部痤疮临床观察

目的:探索中医中药联合强脉冲光治疗面部痤疮的有效方法。方法:将113例确诊为寻常性痤疮的患者随机分为两组。治疗组采用滋阴清热、解毒活血、养阴润肤法,自拟解毒润肤汤加减治疗,同时配合运用强脉冲光技术治疗;对照组单纯运用强脉冲光技术治疗,两组均外用莫匹罗星软膏,1个疗程后进行疗效评价。结果:治疗组总有效率91.94%,对照组总有效率78.43%,两组间比较有明显差异(P<0.05)。结论:中医中药联合强脉冲光治疗面部痤疮有效,值得临床推广。     

强脉冲光结合激光治疗面部痤疮瘢痕的临床护理观察

[目的]探讨面部痤疮病人运用强脉冲光结合激光的护理效果。[方法]选取66例面部痤疮病人为研究对象,采用随机数字表法分为对照组与观察组各33例,对照组行基础护理,观察组在对照组基础上行针对性护理,比较两组病人的瘢痕恢复情况及恢复时间和病人满意度。[结果]观察组的总有效率为96.67%,较对照组81.81%显著增高,差异具有统计学意义(P <0.05);观察组的恢复时间为7.82 d±2.63 d,对照组的恢复时间为10.67 d±3.81 d,观察组病人满意度为93.94%,对照组为75.76%,差异有统计学意义(P <0.05)。[结论]针对性护理对术后面部痤疮瘢痕的恢复有重要意义。     

强脉冲光治疗白癜风的临床分析

目的观察应用320nm强脉冲光治疗白癜风的临床效果。方法126例寻常型白癜风患者,应用320nm强脉冲光选择个性化治疗参数对皮损进行照射,1次／周,10次和20次治疗后评价其临床效果。结果10次治疗结束后,总有效率为77．0％（97／126）,20次治疗结束后,有效率为90．5％（114／126）;从皮损部位看,面颈部、躯干部和四肢在10次治疗结束后的有效率,分别为83．1％（49／59）、79．6％（35／44）和56．5％（13／23）,面颈部和躯干的有效率明显高于四肢（P〈0．05）,面颈部与躯干部的有效率无明显差异（P〉0．05）。结论应用320nm强脉冲光治疗白癜风的临床效果肯定,方便安全。     

强脉冲光治疗面部痤疮印迹的疗效观察

目的 评价强脉冲光治疗痤疮印迹的疗效和安全性。方法 回顾2020年1月至2021年12月于大连市皮肤病医院门诊确诊的60例痤疮印迹患者,年龄16-39岁,病程3周-2年。观察组30例采用强脉冲光治疗,对照组30例未采用相关治疗方式,所有患者均完成3次治疗及随访。根据医生整体评价法（PGA）评价疗效。采用Mann-Whitney U检验分析比较疗效差异。结果 采用Mann-Whitney U检验分析两组治疗后疗效PGA评分结果。结果显示与第1次治疗后相比,随着治疗次数的增加PGA评分逐渐提升。观察组和对照组治疗后疗效PGA评分差异具有统计学意义（P<0.05）。两组患者治疗后均未出现水疱、结痂等不良反应。结论 强脉冲光治疗痤疮印迹能够缩短疗程,快速改善症状,治疗安全,值得临床推广。     

脉冲染料激光与强脉冲光早期干预瘢痕的疗效对比:一项76例病例的回顾性研究

目的 比较PDL和IPL两种常用的血管靶向光电手段在瘢痕早期管理中的疗效.方法 回顾2019年1月至2020年5月,进行PDL或IPL早期干预瘢痕的患者,mVSS量表评价瘢痕情况.结果 共76例患者,治疗3次后,两组总分及各因素评分均低于治疗前,组间未见统计学差距(P=0.467).PDL组血管显著低于IPL组(P=0...     

420nm强脉冲光治疗中重度痤疮的临床观察

目的明确420nm强脉冲光治疗中重度痤疮的临床效果。方法将入选的86例中重度痤疮患者随机分为两组,观察组(43例)采用420nm强脉冲光治疗,对照组给予米诺环素口服治疗,比较两组患者的治疗效果。结果观察组总有效率为93.02%,对照组总有效率为81.40%,观察组总有效率明显高于对照组,差异有统计学意义(P0.05)。结论应用420nm强脉冲光治疗中重度痤疮,能显著改善患者的皮损,临床应用价值明显。     

强脉冲光治疗皮肤光老化的临床效果评价

目的探讨强脉冲光在光老化皮肤治疗中的有效性。方法 选取2022年5月-2022年6月至我院就诊的30例面部光老化皮肤患者为研究对象,所有患者均采用多波长脉冲光治疗平台进行3次治疗,每次治疗间隔时长为30d,观察其有效性、不良反应的发生率及患者满意度。结果 经过医师主观评价,所有患者在结束治疗后30d的肤质肤色、毛细血管扩张、毛孔粗大及色素沉着等维度的总体改善率分别为96.66%、100.00%、86.66%、93.33%;在治疗后,30例患者的皮肤含水量、弹性值较治疗前均有升高,皱纹、紫外线斑点、棕色斑点及经皮失水量均有降低,差异均具有统计学意义(P<0.05);30例患者中,面部红斑3例、皮肤脱屑1例、皮肤轻度刺激感1例,不良反应发生率为16.67%(5例),其余患者均无不良反应出现。结论 对光老化皮肤患者进行多波长脉冲光治疗平台治疗,可明显改善患者的肤质肤色、毛细血管扩张、毛孔粗大及色素沉着等问题,提高患者的皮肤含水量、皮肤弹性,改善肤质及皱纹,降低不良反应的发生率,属于一种安全、有效的治疗方式,值得临床推广应用。     

强脉冲光治疗面部皮肤光老化171例临床护理

目的:探讨强脉冲光治疗面部皮肤光老化患者的护理方法。方法:采用强脉冲光对171例面部皮肤光老化患者进行治疗,4周为1个疗程,持续治疗5次,治疗后给予全面、科学的护理。观察患者疗效和不良反应。结果:本组患者毛细血管扩张、色素沉着、毛孔粗大以及皱纹细小总有效率分别为98.27%、92.50%、70.59%、86.36%;其中治疗后额部出现色素沉着、额部起水泡各1例,不良反应率5.00%,2周后症状均自行消失,未留痕迹。结论:采用强脉冲治疗面部皮肤光老化患者,治疗效果好,不良反应少,值得推广应用。     

强脉冲光治疗雀斑的护理

总结了强脉冲光治疗262例雀斑患者的临床护理。主要包括对患者采用强脉冲光治疗观察并配合治疗前、治疗中、治疗后的精心护理,治疗有效率100%,患者满意。认为患者治疗前深刻认识,治疗后加强自我护理,通过耐心亲切的沟通是强脉冲光疗雀斑成功并降低复发率的关键。     

AOPT强脉冲光在轻度面部皮肤松弛中的应用

目的 观察第七代强脉冲光AOPT对面部轻度皮肤松弛的治疗效果.方法 治疗前清洁面治疗区域,给予强脉冲光治疗(科医人公司M22第七代AOPT).光斑大小3.5cm×1.5cm.640nm滤光片,脉宽15～18ms,三脉冲,时间延迟30～35ms,能量15～19J/cm2,Vascular滤光片,脉宽12～15ms,双脉冲...     

调Q激光联合强脉冲光治疗黄褐斑的meta分析

目的 运用Meta分析,综合评价调Q激光联合强脉冲光治疗黄褐斑的临床疗效.方法 计算机检索Pubmed、中国知网、万方、维普、Cochrane、Web of science、Elsevier science等数据库,收集调Q激光联合强脉冲光与调Q激光治疗黄褐斑的随机对照试验(Randomized controlled ...     

A型肉毒毒素联合强脉冲光治疗痤疮疗效观察

目的 观察A型肉毒毒素联合强脉冲光(IPL)治疗痤疮的临床疗效及安全性.方法 将入选的83例患者随机分为3组,治疗组(30例)予A型肉毒毒素联合强脉冲光治疗,对照1组(27例)予A型肉毒毒素治疗,对照2组(26例)予强脉冲光治疗,在第12周末观察疗效.结果 治疗结束后,治疗组有效率为80％,对照1组有效率为59.26...     

The interaction of broadband intense pulsed light (IPL) and skin during a multi-pulse application

Intense pulsed light (IPL) systems are being presented as an alternative to conventional laser therapy for the treatment of vascular lesions. Broad spectral emission, radiant exposure, and pulse time are the key parameters for any IPL system used in clinical practice. Herein, we present the concept of using multi-pulse delivery to improve the vascular damage caused by IPL light.

The result of our animal study shows an increase in tissue temperature that depends on the number of applied IPL pulses. However, this temperature increase is not a function of heat accumulation. In our study, the peak temperature after each pulse decreased to baseline prior to each successive pulse. A temperature increase of 25 °C is possible with five consecutive 30 ms pulses of 18 J/cm² with a 9 s time interval. We show that in healthy, human-like skin, multi-pulse IPL can achieve selective vascular and perivascular damage with little thermal injury to the epidermis and dermis after proper cooling during treatment. The thermal damage of the vessels could have been enhanced due to an increased blood perfusion that is caused by the multiple pulses. The IPL system provides the clinician a treatment modality with more adjustable parameters to improve the clinical response of various skin types and vascular lesions. We theorize that port-wine stains should respond to multi-pulse IPL therapy in a similar fashion to our healthy, human skin model.     

Management of rosacea with intense pulsed light (IPL) systems and laser

A combination of different clinical symptoms is represented under the broad rubric of rosacea. These consist of facial flushing, erythema with the appearance of telangiectatic vessels of the face, eruption of inflammatory papules and pustules, and hypertrophy of the sebaceous glands with fibrosis. The disease can be characterized by different phases. Classical topical and systemic medications lack sufficient reduction for the main parts of the disease, for flushing attacks and dilated vessels. The impressive results obtained by using intense pulsed light (IPL) and lasers in treating these symptoms indicate that they should finally be a part of standard treatment regimes for rosacea therapy.     

高频超声定量评估鲜红斑痣光动力疗效的应用价值

目的 探讨高频超声定量评估光动力疗法治疗皮肤鲜红斑痣的应用价值.方法 选取60例鲜红斑痣患者,应用高频超声分别于光动力治疗前后测量皮损处皮肤厚度、对称部位正常皮肤厚度,计算皮损增厚厚度,在超声多普勒模式下观测皮肤血流并进行Adler血流分级,比较患者治疗前后皮损增厚厚度和血流分级变化.所有患者于同一拍摄条件下拍摄治疗前...     

Side effects and complications using intense pulsed light (IPL) sources

Lasers have been well known for about 50 years, while flash lamps, also called intense pulsed light (IPL) sources, have been available for clinical applications for less than 20 years. There are many differences between lasers and IPL: a laser emits monochromatic light, whereas an IPL emits a whole range of wavelengths between approximately 250 and 1200 nm. Cut-off filters reduce this range and enable the treatment of different skin conditions. Water acts as a cooling agent by absorbing the emitted infrared light. As a broad spectrum of wavelengths is not absorbed by the chromophores of skin, unspecific heating of the surrounding tissue occurs when using therapeutic energy densities. Flash lamps are used for a variety of indications, such as hair removal, treatment of vascular and pigmented lesions and photorejuvenation. All these applications can be performed with one device by changing the cut-off filters; however, the therapeutic range is rather small and therefore, negative side effects such as burns, blisters, vesicles, erosions and crust formation, as well as hypo- and hyperpigmentations are common. All precautions pertaining to laser treatment of the skin have to be observed with flash-lamp applications as well; in particular, a clear diagnosis has to be established before treatment, and if treatment is performed by non-medical staff it has to be supervised by a physician.     

420nm强脉冲光结合水光注射治疗中重度痤疮的有效性及对GAGS评分的影响研究

目的 420nm强脉冲光联合水光注射治疗中重度痤疮疗效分析.方法 以随机样本抽样法,在我院收治的94例中重度痤疮患者中随机分为对照组、观察组,各47例,对照组:单纯采用420nm强脉冲光治疗,观察组:应用420nm强脉冲光联合水光注射治疗,对比两组治疗有效率、血清因子水平、皮肤屏障功能及痤疮综合分级系统(GAGS)评分...     

肉毒毒素联合强脉冲光治疗玫瑰痤疮难治性红斑和潮红

目的目前临床治疗以面部红斑和潮红为主要表现的玫瑰痤疮仍然比较棘手,本研究报道2例应用肉毒毒素联合强脉冲光治疗顽固性玫瑰痤疮患的案例,希望临床治疗提供方新思路.方法肉毒毒素总剂量为30-50U/次,注射点间隔1cm交错覆盖在面部红斑处,改善血管神经功能,减轻面部阵发性潮红.结果与治疗前相比,治疗部位临床症状明显缓解,VISIA皮肤图像分析仪显示红斑明显减轻,治疗后通过综合日常管理皮肤,随访时间未见症状复发.结论肉毒毒素联合强脉冲光可用于治疗玫瑰痤疮难治性红斑和面部潮红,对其疗效及安全性需在今后的临床中再进行进一步大样本量观察及探讨.