小肠原发性鳞状细胞癌一例

患者男,63岁。以“阵发性腹痛2个月,加重伴肛门停止排便4天”于2003年9月9日入院。体检:右下腹可见肠型和蠕动波,肠鸣音2-3次/分,可闻及气过水声。腹部立卧位X线片示:小肠低位机械性肠梗阻。临床诊断:小肠肿瘤。术中见腹腔内腹水约1500 ml,淡黄色澄清。小肠距屈氏韧带约170 cm处可见一6 cm×5 cm×4 cm大小包块,形状不规则,菜花状,不光滑,质硬,将小肠包裹其中。近侧小肠及结肠空虚,包块附近肠系膜淋巴结肿大。     

胃原发性鳞状细胞癌一例

胃原发性鳞状细胞癌一例赵名春，申永璋，付青患者男，４７岁。主因上腹痛７月余、食后上腹饱胀１０天于１９９０年６月１日以“胃癌”收入院。查体：上腹部未扪及明显包块。于１９９０年６月６日行胃癌根治术。手术所见：胃窦部肿块直径约１０ｃｍ，与胰头、横结肠粘连。...     

胰腺原发性透明细胞鳞状细胞癌一例

胰腺鳞状细胞癌少见,其中透明细胞亚型尤为罕见,容易误诊为其他肿瘤。我们报道1例胰腺原发性透明细胞鳞状细胞癌,镜下以透明细胞形态为主。该病例侵袭性强,诊断时淋巴结已转移,术后20余天发现肝、骨多发转移灶。     

颌骨内原发性鳞状细胞癌一例

颌骨内原发性鳞状细胞癌一例王泽兴，袁延山患者女，８０岁。２年前自觉右腮部疼痛不适，渐肿胀，同侧磨牙区疼痛及下唇麻木。曾在本地医院就治。在肿胀区行穿刺数次，用抗炎药物治疗无效，且逐渐加重半年，以“下颌骨肿物”于１９９３年７月２５日入院。查体见患者下颌骨...     

胆囊原发性鳞状细胞癌1例

患者男性,56岁,因无明显诱因上腹疼痛2 个月入院.以右上腹部疼痛明显,呈间断性绞痛,伴腰背部放射痛,无恶心、呕吐等症状.体检:腹部平坦,未见胃肠型及蠕动波,皮肤及黏膜可见黄染,右上腹可触及压痛,无明显反跳痛及肌紧张,肝脾肋下未触及,未触及包块,Murphy征阴性,移动性浊音阴性,肠鸣音正常.MRCP示:胆囊底部结节,...     

原发性十二指肠鳞状细胞癌2例

例1,女性,75岁。患者近2个月来无明显诱因出现腹痛,呈持续性隐痛,以右上腹为重,可耐受,伴纳差、乏力、恶心、呕吐等症状,于2009年11月16日入院。入院查体:全身皮肤黏膜及巩膜无黄染及出血点,全身浅表淋巴结未触及明显肿大,心肺听诊正常。腹平软,右上腹压痛(+),无反跳痛,肝脾肋下未触及,未扪及包块。实验室检查:AFP:4.72 ng/ml(正常参考值0～5.8 ng/ml),CEA:15.18 ng/ml     

卵巢原发性鳞状细胞癌2例

例1,52岁,5年前无明显诱因下出现左侧腰部疼痛,呈持续性隐胀痛,无放射痛,改变体位无缓解,3个月前症状明显加重.泌尿系彩超示:(1)左侧输尿管上段结石并左侧肾积水;(2)盆腔实液混合性占位:卵巢病变?妇科检查:阴窥镜未能暴露子宫颈,双合诊可触及盆腔较大包块,如孕4个月大小子宫,质硬,活动欠佳,表面光滑,考虑子宫肌瘤?...     

胆囊原发性鳞状细胞癌1例

正患者女性,70岁,因右上腹疼痛20天,加重1周入院。既往有胆囊炎病史,无手术史。腹部MRI平扫+增强示胆囊体积增大,胆囊壁不规则增厚,其内信号不均(图1),考虑胆囊癌。其余腹部区域未见明显异常。术中见右侧结肠旁沟有一巨大脓肿,大小15 cm×10 cm×10 cm,脓肿与侧腹壁、前腹壁及横结肠、胆囊、肝脏及胃粘连严重,分离粘连后见脓肿内有大量黄色脓液溢出,吸尽脓液后见胆囊区有一包     

胃原发性鳞状细胞癌2例

例1女性,77岁,因腹胀入院.胃镜检查示鳞状细胞癌,遂行全胃切除根治术.患者无吸烟史,术后随访5年,全身CT示无其他部位肿瘤;例2男性,68岁,吸烟史近40年,因呕血入院.胃镜检查示鳞状细胞癌.行胃次全切根治术,术后随访4年,全身CT示无其他部位肿瘤.     

原发性乳腺鳞状细胞癌二例

例1女,50岁.发现左侧乳腺肿块5 d于2008年9月15日入院.体检:左乳外上象限可触及-2.0 cm × 1.5 cm肿块,质硬,无压痛,边界不清,活动尚可,乳头无溢液、无内陷,皮肤无橘皮样改变.术中冷冻切片诊断为浸润性乳腺癌,倾向于鳞状细胞癌.行左侧乳腺癌改良根治术及左腋窝淋巴结清扫.     

Primary squamous cell carcinoma of the endometrium: a case report

Squamous cell carcinoma of the endometrium is extremely rare female genital malignancy. Only 64 cases have been reported in the literature. A case of primary squamous cell carcinoma of endometrium in a 55-year old-woman is reported. Examination revealed pyometra and cervical stenosis. A total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathology confirmed the diagnosis.     

Primary squamous cell carcinoma of the breast: a case report

INTRODUCTION: Primary squamous cell carcinoma (SCC) of the breast is an extremely rare entity and it has a low incidence in comparison with all other mammary cancers. MATERIAL AND METHODS: We describe a case of SCC of the breast in a 55 year old woman who presented with a painless mass located in the external quadrant of the left breast. The neoformation, once removed, was tamponate formalin fixed and routinely processed for inclusion in paraffin. Sections were stained with haematoxilin-eosin and immunohistochemical and electron microscopy investigations were performed. RESULTS: Histologically, the neoplasia was characterized by cystic cavities covered by nests and sheaths of poorly differentiated squamous cells with keratinized areas. Mitotic activity was high, as well as cellular proliferative index, evaluated by Mib-1 (ki 67) antibody. At immunohistochemistry, the tumor cells were diffusely positive for high molecular weight cytokeratins and c-erbB-2, negative for vimentin, estrogen and progesterone. CD68 and LCA were positive only in the inflammatory cells. Electron microscopy confirmed the epithelial nature of the neoplastic cells. A diagnosis of SCC of the breast was made, and a radical mastectomy was performed. CONCLUSIONS: We make a brief review of the literature and discuss the main histologic criteria for the differential diagnosis with adenocarcinoma of the breast with squamous metaplasia.     

Primary squamous cell carcinoma of the liver: a case report

Primary squamous cell carcinoma (SCC) of the liver is very rare, and few cases have been reported in Korea. Primary SCC of the liver is known to be associated with hepatic cysts and intrahepatic stones. A 71-year-old male was admitted to our hospital, and a abdominal computed tomography scan revealed a 10 × 6 cm mass in the liver. Analysis of a biopsy sample suggested SCC, and so our team performed a thorough workup to find the primary lesion, which was revealed hepatoma as a pure primary SCC of the liver with multiple distant metastases. The patient was treated with one cycle of radiotherapy, transferred to another hospital for hospice care, and then died 1 month after discharge.     

Primary squamous cell carcinoma of the thyroid--a case report

A rare case of primary squamous cell carcinoma of the thyroid is reported herein. A 64-year-old Malay lady presented with a gradually enlarging thyroid nodule for the past 6 months and underwent total thyroidectomy. Histopathology revealed a squamous cell carcinoma of the thyroid with complete resection. Possible primary tumour elsewhere was excluded. Postoperative irradiation was given and patient is still alive after 2 years of follow-up.     

原发性子宫内膜鳞状细胞癌伴子宫内膜不典型增生1例

原发性子宫内膜鳞状细胞癌(primary endometrial squamous cell carcinomas, PESCC)是一种罕见的子宫内膜癌。本文报道1例55岁患者, 刮宫标本及经腹腔镜筋膜外全子宫切除标本组织学形态均显示不同分化程度的鳞状上皮呈浸润性生长, 并见短梭形细胞, 胞质丰富、透亮。刮宫标本中未见正常子宫内膜腺体及异常腺性结构;全子宫切除标本中短梭形与鳞状上皮穿插生长, 侵犯浅肌层, 周围子宫内膜可见慢性子宫内膜炎, 局灶符合子宫内膜不典型增生;免疫表型:明确的鳞状上皮成分及短梭形细胞广谱细胞角蛋白、细胞角蛋白(CK)5/6、p63、β-catenin、CD10均阳性, CK7、CDX2阴性。患者随访8个月, 身体状况良好。PESCC需要严格掌握诊断标准, 除外子宫颈来源的鳞状细胞癌及子宫内膜样癌伴广泛鳞化。该文描述PESCC组织学特点、刮宫及全子宫标本诊断难点、阐述其诊断要点, 并复习和总结相关文献。     

Primary squamous cell carcinoma of the stomach: a case report and literature review

Primary squamous cell carcinoma (SCC) of the stomach is rare. Its pathogenesis is also unclear and there are conflicting reports about it in the past. Only about 100 cases have been reported so far in the literature. The current study discusses a new case of gastric squamous cell carcinoma, from a 50-year-old Chinese male patient diagnosed via subtotal gastrectomy with Roux-en-Y reconstruction and D2 lymphadenectomy. In the stomach, an ulcerated mass in the antrum, measuring 12×8×6 cm, was observed. Further, pathological examination of the resected specimen revealed a well-differentiated SCC. Observations indicated tumor cell invasion into the serosa, and encroachment into perigastric regional lymph node. A follow-up abdominal CT scan three months later revealed tumor invasion into the ascending colon. We assume that this invaded mass was transferred from the gastric squamous cell carcinoma. Interestingly, the patient is still alive.