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1.
Rodrigo Milani Daniela de Moraes Aline Sanches Rodrigo Jardim Thais Lumikoski Gabriela Miotto Vitor Hugo Santana Paulo Roberto Brofman 《Brazilian Journal Of Cardiovascular Surgery》2014,29(2):148-155
Introduction
We evaluated with transit time flow the performance of the right and left thoracic arteries when used as a graft for the left anterior descending artery.Methods
Fifty patients undergoing surgery for myocardial revascularization without cardiopulmonary bypass were divided into two groups. In group A patients received graft of right internal mammary artery to the anterior interventricular branch. In group B patients received graft of left internal mammary artery to the same branch. At the end of the operation the flow was assessed by measuring transit time.Results
In group A, mean age was 60.6±9.49 years. The average height and weight of the group was 80.4±10.32 kg and 169.2±6.86 cm. The average number of grafts per patient in this group was 3.28±1.49. The mean flow and distal resistance obtained in right internal thoracic artery was 42.1±23.4 ml/min and 2.8±0.9 respectively. In group B, the mean age was 59.8±9.7 years. The average height and weight of this group was 77.7±14.22 kg and 166.0±8.2 cm. The average number of grafts per patient in this group was 3.08 ±0.82. The mean flow and distal resistance observed in this group was 34.2±19.1 ml/min and 2.0±0.7. There were no deaths in this series.Conclusion
Right internal mammary artery presented a similar behavior to left internal mammary artery when anastomosed to the anterior interventricular branch of the left coronary artery. There was no statistical difference between the measured flow obtained between both arteries. 相似文献2.
Maurilio Onofre Deininger Luiz Felipe Pinho Moreira Luiz Alberto Oliveira Dallan Orlando Gomes de Oliveira Daniel Marcelo Silva Magalh?es José Reinaldo de Moura Coelho Eugênia di Giuseppe Deininger Norland de Souza Lopes Ricardo Wanderley Queiroga Elizabeth Ferreira Belmont 《Brazilian Journal Of Cardiovascular Surgery》2014,29(2):192-201
Objective
To assess the patency of the pedicled right internal thoracic artery with an anteroaortic course and compare it to the patency of the left internal thoracic artery , in anastomosis to the left anterior descending artery in coronary artery bypass grafting by using coronary CT angiography at 6 months postoperatively.Methods
Between December 2008 and December 2011, 100 patients were selected to undergo a prospective coronary artery bypass grafting procedure without cardiopulmonary bypass. The patients were randomly divided by a computer-generated list into Group-1 (G-1) and Group-2 (G-2), comprising 50 patients each, the technique used was known at the beginning of the surgery. In G-1, coronary artery bypass grafting was performed using the left internal thoracic artery for the left anterior descending and the free right internal thoracic artery for the circumflex, and in G-2, coronary artery bypass grafting was performed using the right internal thoracic artery pedicled to the left anterior descending and the left internal thoracic artery pedicled to the circumflex territory.Results
The groups were similar with regard to the preoperative clinical data. A male predominance of 75.6% and 88% was observed in G-1 and G-2, respectively. Five patients migrated from G-1 to G-2 because of atheromatous disease in the ascending aorta. The average number of distal anastomoses was 3.48 (SD=0.72) in G-1 and 3.20 (SD=0.76) in G-2. Coronary CT angiography in 96 re-evaluated patients showed that all ITAs, right or left, used in situ for the left anterior descending were patent. There were no deaths in either group.Conclusion
Coronary artery bypass grafting surgery involving anastomosis of the anteroaortic right internal thoracic artery to the left anterior descending artery has an outcome similar to that obtained using the left internal thoracic artery for the same coronary site. 相似文献3.
Ricardo Medeiros Piantá Andres Di Leoni Ferrari Aline Almeida Heck Débora Klein Ferreira Jacqueline da Costa Escobar Piccoli Luciano Cabral Albuquerque Jo?o Carlos Vieira da Costa Guaragna Jo?o Batista Petracco 《Brazilian Journal Of Cardiovascular Surgery》2015,30(2):164-172
Introduction
Disturbances of the cardiac conduction system are frequent in the postoperative period of coronary artery bypass surgery. They are mostly reversible and associated with some injury of the conduction tissue, caused by the ischemic heart disease itself or by perioperative factors.Objective
Primary: investigate the association between perioperative factors and the emergence of atrioventricular block in the postoperative period of coronary artery bypass surgery. Secondary: determine the need for temporary pacing and of a permanent pacemaker in the postoperative period of coronary artery bypass surgery and the impact on hospital stay and hospital mortality.Methods
Analysis of a retrospective cohort of patients submitted to coronary artery bypass surgery from the database of the Postoperative Heart Surgery Unit of the Sao Lucas Hospital of the Pontifical Catholic University of Rio Grande do Sul, using the logistic regression method.Results
In the period from January 1996 to December 2012, 3532 coronary artery bypass surgery were carried out. Two hundred and eighty-eight (8.15% of the total sample) patients had atrioventricular block during the postoperative period of coronary artery bypass surgery, requiring temporary pacing. Eight of those who had atrioventricular block progressed to implantation of a permanent pacemaker (0.23% of the total sample). Multivariate analysis revealed a significant association of atrioventricular block with age above 60 years (OR=2.34; CI 95% 1.75-3.12; P<0.0001), female gender (OR=1.37; CI 95% 1.06-1.77; P=0.015), chronic kidney disease (OR=2.05; CI 95% 1.49-2.81; P<0.0001), atrial fibrillation (OR=2.06; CI 95% 1.16-3.66; P=0.014), functional class III and IV of the New York Heart Association (OR=1.43; CI 95% 1.03-1.98; P=0.031), perioperative acute myocardial infarction (OR=1.70; CI 95% 1.26-2.29; P<0.0001) and with the use of the intra-aortic balloon in the postoperative period of coronary artery bypass surgery (OR=1.92; CI 95% 1.21-3.05; P=0.006). The presence of atrioventricular block resulted in a significant increase in mortality (17.9% vs. 7.3% in those who did not develop atrioventricular block) (OR=2.09; CI 95% 1.46-2.99; P<0.0001) and a longer hospital stay (12.75 days x 10.53 days for those who didn''t develop atrioventricular block) (OR=1.01; CI 95% 1.00-1.02; P=0.01).Conclusions
In most cases, atrioventricular block in the postoperative period of coronary artery bypass surgery is transient and associated with several perioperative factors: age above 60 years, female sex, chronic kidney disease, atrial fibrillation, New York Heart Association functional class III or IV, perioperative acute myocardial infarction and use of an intra-aortic balloon. Its occurrence prolongs hospitalization and, above all, doubles the risk of mortality. 相似文献4.
Hasan Uncu Mehmet Acipayam Levent Altinay Pinar Do?an Isil Davarc? ?brahim ?zs?yler 《Brazilian Journal Of Cardiovascular Surgery》2014,29(4):569-573
Introduction
In this retrospective study, we aimed to determine the risk factors for coronary artery bypass surgery in patients under 45 years of age, and evaluate the early postoperative results and the effect of gender.Methods
A total of 324 patients under 45 years of age who undergone on-pump coronary artery bypass surgery between April 12, 2004 and January 10, 2012 were included to the study. Patients divided into groups as follows: Group 1 consisted of 269 males (mean age 41.3), Group 2 consisted of 55 females (mean age 41.6). Preoperative risk factors, intraoperative and postoperative data and early mortality rates of the groups were compared.Results
Smoking rate was significantly higher in Group 1. Diabetes mellitus incidence and body mass index were significantly higher in Group 2 (P values P=0.01; P=0.0001; P=0.04 respectively). The aortic cross-clamping and cardiopulmonary bypass time and number of grafts per patient were significantly higher in Group 1 (P values P=0.04; P=0.04; P=0.002 respectively). There were no deaths in either group.Conclusion
We found that gender has no effect on early mortality rates of the coronary bypass surgery patients under 45 years. 相似文献5.
Fatih Aygün Mehmet ?zülkü Murat Günday 《Brazilian Journal Of Cardiovascular Surgery》2015,30(6):597-604
OBJECTIVE
The present study consisted of patients who underwent on-pump coronary artery bypass grafting (CABG) and off-pump CABG and investigated effect of using cardiopulmonary bypass (CPB) on the amount of postoperative drainage and blood products, red blood cell (RBC), free frozen plasma (FFP) given in the intensive care unit in 60-80-year-old patients who underwent CABG.METHODS
The present study comprises a total of 174 patients who have undergone coronary artery bypass graft (off-pump or on-pump CABG) surgery in our clinic in between 2012-2015 year.RESULTS
It was observed that the amount of drainage in the first 24 postoperative hours was lower in the on-pump CABG group (Group 1) when compared to off-pump group (Group 2) (Group 1 vs. Group 2; 703.5±253.8 ml vs. 719.6±209.4 ml; P =0.716). However, the amount of drainage in the second 24 hours was statistically significantly lower in the off-pump CABG group (Group 1 vs. Group 2; 259.8±170.6 ml vs. 190.1±129.1 ml; P =0.016). With regard to the amount of overall drainage, no statistically significant difference was observed between the two groups. Group 1 needed RBC transfusion higher than Group 2 (Group 1 vs. Group 2; 2.2±1.3 bag vs. 1.2±0.9 bag; P <0.001).CONCLUSION
We can say that CPB influences the amount of second 24-hour drainage which indexed body surface area. In addition, CPB decreases hct, hb, thrombocyte count in ICU arrived, after 24 hours in postoperative period. Reduced thrombocyte counting effect can be appeared after 48 hours in the postoperative period of CPB. 相似文献6.
Objective
The present study investigated effect of using pump on postoperative pleural effusion in patients who underwent coronary artery bypass grafting.Methods
A total of 256 patients who underwent isolated coronary artery bypass grafting surgery in the Cardiovascular Surgery clinic were enrolled in the study. Jostra-Cobe (Model 043213 105, VLC 865, Sweden) heart-lung machine was used in on-pump coronary artery bypass grafting. Off-pump coronary artery bypass grafting was performed using Octopus and Starfish. Proximal anastomoses to the aorta in both on-pump and off-pump techniques were performed by side clamps. The patients were discharged from the hospital between postoperative day 6 and day 11.Results
The incidence of postoperative right pleural effusion and bilateral pleural effusion was found to be higher as a count in Group 1 (on-pump) as compared to Group 2 (off-pump). But the difference was not statistically significant [P>0.05 for right pleural effusion (P=0.893), P>0.05 for bilateral pleural effusion (P=0.780)]. Left pleural effusion was encountered to be lower in Group 2 (off-pump). The difference was found to be statistically significant (P<0.05, P=0.006).Conclusion
Under the light of these results, it can be said that left pleural effusion is less prevalent in the patients that underwent off-pump coronary artery bypass grafting when compared to the patients that underwent on-pump coronary artery bypass grafting. 相似文献7.
Maximo Guida Gustavo Guida Giuseppina Pecora Estefania De Garate 《Brazilian Journal Of Cardiovascular Surgery》2014,29(3):459-462
Third REDO-CABG is a challenge for the surgical team. Usually a patent mammary is theonly graft working and the sternotomy becomes a risky procedure. Injury to a patentgraft has been associated to a high mortality rate. Many different approaches havebeen proposed. We describe a novel technique to approach the right coronary arterythrough a right anterior small thoracotomy using the right mammary prolonged withsaphenous vein for grafting the posterior descending artery on the beating heart. Thetechnique is very simple and feasible because anatomically the right coronary arteryand the right mammary are very close and the mobilization of the heart isminimal. 相似文献
8.
Ozan Erdem Mehmet Erdem Memeto?lu Ali ?hsan Tekin ümit Arslan ?zgür Akkaya Rasim Kutlu ?lhan G?lba?? 《Brazilian Journal Of Cardiovascular Surgery》2015,30(4):459-465
Objective
This study aimed to show the effects of intra-operative diltiazem infusion on flow in arterial and venous grafts in coronary artery bypass graft surgery.Methods
Hundred fourty patients with a total of 361 grafts [205 (57%) arterial and 156 (43%) venous] underwent isolated coronary surgery. All the grafts were measured by intraoperative transit time flow meter intra-operatively. Group A (n=70) consisted of patients who received diltiazem infusion (dose of 2.5 microgram/kg/min), and Group B (n=70) didn''t receive diltiazem infusion.Results
Mean graft flow values of left internal mammary artery were 53 ml/min in Group A and 40 ml/min in Group B (P<0.001). Pulsatility index (PI) values of left internal mammary artery for Group A and Group B were 2.6 and 3.0 respectively (P<0.001). No statistically significant difference was found between venous graft parameters.Conclusion
We recommend an effect of diltiazem infusion in increasing graft flows in coronary artery bypass graft operations. 相似文献9.
Mathias H. Aazami Mohammad Abbasi-Teshnizi Shahram Amini Nasim Sadat Lotfinejad 《Brazilian Journal Of Cardiovascular Surgery》2014,29(4):657-662
Complete arterial revascularization for the right coronary artery is underused mainlydue to technical issues. Herein we report on a new approach for complete arterialrevascularization of arterial revascularization for the right coronary arterybranches. Complete arterial revascularization for the right coronary arteryrevascularization was performed in 8 patients using a reverse T composite arterialgraft. None of the patients suffered perioperative myocardial infarction. Allpatients underwent noninvasive coronary imaging, displaying an early patency rate of100%. Complete arterial arterial revascularization for the right coronary arteryrevascularization using a reverse T graft offers a new paradigm with enhancedtechnical flexibility in performing all arterial myocardial completerevascularizations in selected patients. 相似文献
10.
Pedro Gabriel Melo de Barros e Silva Ant?nio Claudio do Amaral Baruzzi Denise Louzada Ramos Mariana Yumi Okada José Carlos Teixeira Garcia Fernanda de Andrade Cardoso Marcelo Jamus Rodrigues Valter Furlan 《Brazilian Journal Of Cardiovascular Surgery》2015,30(6):660-663
OBJECTIVE
To report the initial changes after quality-improvement programs based on STS-database in a Brazilian hospital.METHODS
Since 2011 a Brazilian hospital has joined STS-Database and in 2012 multifaceted actions based on STS reports were implemented aiming reductions in the time of mechanical ventilation and in the intensive care stay and also improvements in evidence-based perioperative therapies among patients who underwent coronary artery bypass graft surgeries.RESULTS
All the 947 patients submitted to coronary artery bypass graft surgeries from July 2011 to June 2014 were analyzed and there was an improvement in all the three target endpoints after the implementation of the quality-improvement program but the reduction in time on mechanical ventilation was not statistically significant after adjusting for prognostic characteristics.CONCLUSION
The initial experience with STS registry in a Brazilian hospital was associated with improvement in most of targeted quality-indicators. 相似文献11.
Rune Haaverstad Nicola Vitale R. Ian Williams Alan G. Fraser 《Scandinavian cardiovascular journal : SCJ》2013,47(2):95-99
Objective : Epicardial ultrasound scanning was applied during coronary surgery to assess coronary artery stenoses and quality of distal graft anastomoses, with special emphasis to the left anterior descending artery (LAD). Design : Twenty-three patients with coronary artery disease (M:F 19:4, mean age 65.0 - 9.5 years) had coronary artery bypass grafting (CABG) on cardiopulmonary bypass. Intraoperative scanning of coronary artery stenoses and graft anastomoses was performed with a new 10 MHz linear array Vingmed transducer connected to a GE Vingmed System FiVe echocardiography unit. Coronary stenoses detected by ultrasound were compared with preoperative angiograms. Intraoperatively, coronary graft flow was assessed with a Medi-Stim transit-time flowmeter. Results : Twenty LADs were investigated. In 17 LADs (85%) stenoses were clearly identified. In three LADs (15%) stenoses were not identified because LADs were deeply intramyocardial or the stenosis was very proximal. There was a significant correlation between LAD stenoses detected by ultrasound and angiogram ( R = 0.7; p < 0.01). Mean number of grafts was 3.8 - 0.9. Of 26 LAD anastomoses assessed, good images were obtained in 22 cases (84.4%); the mean LAD diameter measured 1 cm below the anastomosis was 1.6 - 0.2 mm. In two LADs images were rated fair and in two LADs images were poor because of intramyocardial LAD. No technical error of the anastomoses was detected. All grafts had good flows as ascertained by flow measurements. Conclusion : Epicardial ultrasound scanning with the new 10 MHz transducer allowed satisfactory imaging of coronary stenoses and graft anastomoses. Factors limiting the quality of imaging are proximal lesions, intramyocardial vessel, vessel tortuosity, and extensive calcifications. Epicardial ultrasound scanning with updated technology should become a further advancement to graft assessment during off-pump coronary surgery. 相似文献
12.
Marcos Aurélio Barboza de Oliveira Antonio Carlos Brandi Carlos Alberto dos Santos Paulo Henrique Husseini Botelho 《Brazilian Journal Of Cardiovascular Surgery》2015,30(4):443-448
Introduction
After removal of endotracheal tube and artificial ventilation, ventilatory support should be continued, offering oxygen supply to ensure an arterial oxygen saturation close to physiological.Objective
The aim of this study was to investigate the effects of positive-end expiratory pressure before extubation on the oxygenation indices of patients undergoing coronary artery bypass grafting.Methods
A randomized clinical trial with seventy-eight patients undergoing coronary artery bypass grafting divided into three groups and ventilated with different positive-end expiratory pressure levels prior to extubation: Group A, 5 cmH2O (n=32); Group B, 8 cmH2O (n=26); and Group C, 10 cmH2O (n=20). Oxygenation index data were obtained from arterial blood gas samples collected at 1, 3, and 6 h after extubation. Patients with chronic pulmonary disease and those who underwent off-pump, emergency, or combined surgeries were excluded. For statistical analysis, we used Shapiro-Wilk, G, Kruskal-Wallis, and analysis of variance tests and set the level of significance at P<0.05.Results
Groups were homogenous with regard to demographic, clinical, and surgical variables. There were no statistically significant differences between groups in the first 6 h after extubation with regard to oxygenation indices and oxygen therapy utilization.Conclusion
In this sample of patients undergoing coronary artery bypass grafting, the use of different positive-end expiratory pressure levels before extubation did not affect gas exchange or oxygen therapy utilization in the first 6 h after endotracheal tube removal. 相似文献13.
Nevzat Erdil Murat Kaynak K?ksal D?nmez Olcay Murat Disli Bektas Battaloglu 《Brazilian Journal Of Cardiovascular Surgery》2014,29(4):581-587
Objective
Postoperative atrial fibrillation is a common complication after cardiac surgery, with an incidence as high as 20-50%. Increased age is associated with a significant increase in postoperative atrial fibrillation risk. This common complication is associated with higher morbidity and mortality rates. The aim of this study was to assess the efficacy of nebivolol in preventing atrial fibrillation following coronary artery bypass surgery in patients over 60 years of age.Methods
In this prospective randomized study, 200 patients who were candidates for elective coronary artery bypass surgery were divided into two groups. The first group was administered with nebivolol and the second group was administered with metoprolol. Treatment was initiated four days prior to surgery, and patients were monitored for atrial fibrillation until discharge. Forty-one patients recieved 50 mg metoprolol succinate daily, which was initiated minimum 4 days before surgery.Results
Demographic data were similar in both groups. The incidence of postoperative atrial fibrillation in both groups was similar, with no significant difference being identified [n=20 (20%); n=18 (18%), P=0.718; respectively]. There were not any mortality at both groups during study. Inotropic agent requirement at ICU was similar for both groups [n=12 (12%), n=18 (18%), P=0.32].Conclusion
We compared the effectiveness of nebivolol and metoprolol in decreasing the incidence of postoperative atrial fibrillation, and determined that nebivolol was as effective as metoprolol in preventing postoperative atrial fibrillation at patients. Nebivolol may be the drug of choice due to its effects, especially after elective coronary artery bypass surgery. 相似文献14.
Solange Guizilini Marcela Viceconte Gabriel Tavares da M. Esperan?a Douglas W. Bolzan Milena Vidotto Rita Simone L Moreira Andréia Azevedo Cancio Walter J Gomes 《Brazilian Journal Of Cardiovascular Surgery》2014,29(4):588-594
Objective
To evaluate the lung function and clinical outcome in severe chronic obstructive pulmonary disease in patients undergoing off-pump coronary artery bypass grafting with left internal thoracic artery graft, comparing the pleural drain insertion in the intercostal versus subxyphoid region.Methods
A randomized controlled trial. Chronic obstructive pulmonary disease patients were randomized into two groups according pleural drain site: II group (n=27) - pleural drain in intercostal space; SI group (n=29) - pleural drain in the subxyphoid region. Spirometry values (Forced Vital Capacity - and Forced expiratory volume in 1 second) were obtained on preoperative and 1, 3 and 5 postoperative days. Chest x-ray from preoperative until postoperative day 5 (POD5) was performed for monitoring respiratory events, such as atelectasis and pleural effusion. Pulmonary shunt fraction and pain score was evaluate preoperatively and on postoperative day 1.Results
In both groups there was a significant decrease of the spirometry values (Forced Vital Capacity and Forced expiratory volume in 1 second) until POD5 (P<0.05). However, when compared, SI group presented less decrease in these parameters (P<0.05). Pulmonary shunt fraction was significantly lower in SI group (P<0.05). Respiratory events, pain score, orotracheal intubation time and postoperative length of hospital stay were lower in the SI group (P<0.05).Conclusion
Subxyphoid pleural drainage in severe Chronic obstructive pulmonary disease patients determined better preservation and recovery of pulmonary capacity and volumes with lower pulmonary shunt fraction and better clinical outcomes on early postoperative off-pump coronary artery bypass grafting. 相似文献15.
Luiz Augusto Ferreira Lisboa Omar Asdrubal Vilca Mejia Luiz Felipe Pinho Moreira Luís Alberto Oliveira Dallan Pablo Maria Alberto Pomerantzeff Luís Roberto Palma Dallan Maria Raquel B. Massoti Fabio B. Jatene 《Brazilian Journal Of Cardiovascular Surgery》2014,29(1):1-8
Introduction
The most widely used model for predicting mortality in cardiac surgery was recently remodeled, but the doubts regarding its methodology and development have been reported.Objective
The aim of this study was to assess the performance of the EuroSCORE II to predict mortality in patients undergoing coronary artery bypass grafts or valve surgery at our institution.Methods
One thousand consecutive patients operated on coronary artery bypass grafts or valve surgery, between October 2008 and July 2009, were analyzed. The outcome of interest was in-hospital mortality. Calibration was performed by correlation between observed and expected mortality by Hosmer Lemeshow. Discrimination was calculated by the area under the ROC curve. The performance of the EuroSCORE II was compared with the EuroSCORE and InsCor (local model).Results
In calibration, the Hosmer Lemeshow test was inappropriate for the EuroSCORE II (P=0.0003) and good for the EuroSCORE (P=0.593) and InsCor (P=0.184). However, the discrimination, the area under the ROC curve for EuroSCORE II was 0.81 [95% CI (0.76 to 0.85), P<0.001], for the EuroSCORE was 0.81 [95% CI (0.77 to 0.86), P<0.001] and for InsCor was 0.79 [95% CI (0.74-0.83), P<0.001] showing up properly for all.Conclusion
The EuroSCORE II became more complex and resemblance to the international literature poorly calibrated to predict mortality in patients undergoing coronary artery bypass grafts or valve surgery at our institution. These data emphasize the importance of the local model. 相似文献16.
【摘要】 目的 探讨青年人胃癌的临床病理特点及预后。方法 回顾性分析2005年1月至2010年12月初治的56例青年人胃癌(年龄≤40岁)的临床资料,并随机选取同期56例老年人胃癌(年龄≥60岁)作对照。采用SPSS13.0统计软件分析青年人胃癌的临床病理特点及与预后的关系。结果 56例青年人胃癌女性比例高于男性(χ2 =11.593,P=0.001);肿瘤多位于胃窦部;病理类型以低分化腺癌和未分化癌为主,高于对照组(χ2 =16.586,P<0.001);临床分期以中晚期多见;术后生存中位时间为39.56个月,1、3、5 年生存率分别为80.0%、52.0%、24.0%;行根治性手术患者生存率高于姑息性手术患者(χ2 =5.836,P=0.016);手术方式、肿瘤大小、病理类型、临床分期是影响青年人胃癌预后的主要因素(P<0.05)。结论 青年人胃癌以女性居多,起病隐匿,确诊多为中晚期,恶性程度高,应重视青年人胃癌的早期诊断,尽早行根治性手术,有助于改善患者预后。 相似文献
17.
目的 探讨代谢综合征(metabolic syndrome,MS)对不停跳冠状动脉旁路移植(OPCABG)围术期的影响.方法 2009年8月至2010年3月,连续1060例OPCABG病人分为MS组与非MS组,比较两组的病死率、房颤发生率、多器官衰竭评分(MODS)、心脏外科术后评分(PSCS)、PaO2/FiO2以及心率×中心静脉压/平均动脉压(pressure-adjusted heart rate,PAHR).结果 MS对OPCABG的病死率、房颤发生率、脑卒中、IABP和ECMO、透析的使用率无影响.但手术当天,MS组的MODS评分为2.57±1.62,PSCS评分为4.27±2.15,显著高于非MS组的2.15±1.65,3.92±2.29,P<0.05;PaO2/FiO2在MS组为249.23±110.99,显著低于非MS组的283.33±114.35,P<0.01;MS组的PAHR为9.98±3.54,显著高于非MS组的9.23±3.88,P<0.05.手术后第1天,MS组的MODS评分为3.05±1.64.显著高于非Ms组的2.82±1.72,P<0.05;PaO2/FiO2在MS组为277.11±122.99,显著低于非MS组,318.47±143.84,P<0.05.结论 MS对OPCABG的病死率、房颤发生率、脑卒中、IABP和ECMO、透析的使用率无影响,但在术后当天和术后第1天,MS可以对OPCABG病人的呼吸和循环系统产生短暂的负面影响.Abstract: Objective Metabolic syndrome ( MS), a disorder involving multiple metabolic abnormalities such obesity,hypertension, diabetes or abnormal glucose tolerance and dyslipidemia, has been observed in many patients receiving coronary artery bypass procedures. In this study we try to examine the perioperative effects of metabolic syndrome on the off-pump coronary artery bypass (OPCABG). Methods A prospective study was conducted in 1060 consecutive OPCABG patients who were admited to Beijing Anzhen Hospital from July 2009 to March 2010. The patients were grouped as MS group and non-MS group according to the diagnostic criteria for Chinese metabolic syndrome. The outcomes such as mortality, atrial fibrillation,stroke, staying in ICU for more than three days, use of IABP, ECMO, dialysis, multiple organ dysfunction score ( MOOS) ,postoperative score for cardiac surgery (PSCS), PaO2/FiO2 , heart rate x central venous pressure/mean artery pressure(pressure-adjusted heart rate, PAHR) ,renal and liver function, platelets, and the dosage of vasoactive agents were analyzed and compared between the two groups by x2 test or t test. Results Three hundred and eighty-nine cases were diagnosed with MS among 1060 cases with OPCABG. In the MS group, 17 cases stayed in ICU for more than 3 days, 2 cases died, 76 had atrial fibrillation, 3 had stroke, 18 cases were treated with intra-aortic balloon counterpulsation (IABP). In the non-MS group, 47 cases stayed in ICU for more than 3 days, 12 cases died, 148 had atrial fibrillation, 3 had stroke, 48 cases were treated withIABP, 3 cases received ECMO and 4 cases received dialysis. No significant difference between MS group and non-MS group was identified in the aspects of mortality, atrial fibrillation, stroke, duration of more than three days in ICU, the use of IABP,ECMO, dialysis after OPACBG based on the x2 test(P>0.05). However, on the operative days, the MODS and PSCS in MS group were significantly higher than that in non-MS group (P < 0.05). MODS 2. 57 ± 1. 62 in MS group vs. 2. 15 ± 1.65 in non-MS group, PSCS 4.27 ±2.15 in MS group vs. 3.92 ±2.29 in non-MS group. PaO2/FiO2 in MS group was significantly lower than that in non-MS group (249.23 ± 110.99 vs. 283. 33 ± 114. 35), P < 0. 01. PAHR in MS group was significantly higher than that in non-MS group (9.98 ±3.54 vs. 9.23 ±3. 88), P <0.05. On the first postoperative days, the MODS in MS group was also significantly higher than that in non-MS group (3.05 ±1.64 vs. 2.82 ± 1.72), P<0.05. PaO2/FiO2 in MS group was significantly lower than that in non-MS group (277.11 ±122.99 vs.318.47 ±143.84), P<0.05. Conclusion MS was not a predictor for death, atrial fibrillation, stroke, duration of more than three days in 1CU, the use of IABP, ECMO, dialysis after OPACBG. However, MS had a temporary adverse effect on the respiratory and circulatory systems on the operative day and the first postoperative day after OPCABG. 相似文献
18.
微创伤非体外循环下多支冠状动脉搭桥术的临床应用——20例报道 总被引:1,自引:0,他引:1
我院自1997年10月至1998年10月非体外循环下经胸或胸骨进行了20例微创伤冠状动脉搭桥术(Minimal Invasive Offpump Coronary Artery Bypass,MI-OPCAB)。其中14例经胸骨正中切口,5例左前外侧小切口开胸,1例胸骨正中切口双侧乳内动脉搭桥术(IMA)。所有病例恢复良好,平均随访6个月,全部存活。平均住ICU时间仅为1天。平均住院日为12天。平均住院费用低于传统冠状动脉旁路移植术20%。由于随访时间短,微创伤冠状动脉搭桥术的远期效果尚需证实。 相似文献
19.
Shi-Min Yuan 《Brazilian Journal Of Cardiovascular Surgery》2014,29(4):622-629
Objective
Anomalous origin of coronary artery is uncommon. The taxonomies of anomalous origin of coronary artery are inconsistent and complex. Conceptual and therapeutic debates remain. The aim of the present study is to reappraise the concept of anomalous origin of coronary artery and to discuss the potential hazards and treatment rationale of this anomaly on basis of literature review.Methods
A comprehensive literature review was made in terms of the taxonomies including “simple”, “multiple” and “complex” types of anomalous origin of coronary artery.Results
Anomalous origin of coronary artery can be simply categorized according to the ectopically originated coronary artery. There are a couple of complex anatomical variants: “multiple” type, involving more than one coronary artery or branch, which can be subdivided into 2 subtypes, A) more than one coronary arteries or branches arising from one place; and B) two coronary arteries/branches arising from separate ectopic sites; and “complex” type, associated with acquired heart disease, or congenital heart defects.Conclusion
Sudden cardiac death in anomalous origin of coronary artery is associated with the anatomical features including abnormal coursing, acute angle take-off and ostial abnormalities. Atherosclerosis is prone to be in the right-sided ectopic and retroaortic coursing coronary artery. Surgical treatment is a definitive therapy. Simple coronary artery bypass grafting is not recommended due to the potential hazards of coronary steal phenomenon and poor patency of mammary arterial grafts, and modified maneuvers such as coronary ostial reimplantation, impinged coronary segment unroofing and coronary stent deployment are advocated instead. 相似文献20.
Neda Zeinali Mohammad Hashemi Mohsen Mirmohammadsadeghi Hamid Mirmohammadsadeghi Nahid Eskandari Ali Mohammad Sabzghabaee 《Brazilian Journal Of Cardiovascular Surgery》2015,30(5):557-561