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1.
2007475 MRI manifestations of renal oncocytoma.JI Jiansong(纪建松) , et al. Dept Radiol, Sir Run RunShaw Hosp, Zhejiang Univ, Hangzhou 310016. Chin JRadiol 2007;41(10):1087 -1089. Objective To analyze the MRI findings of renal on-cocytoma, and to improve the ability for the diagnosis.Methods We retrospectively reviewed MRI findings ofsults Sixcases had a solitary lesion, and 1 of themac-companied with renal clear-cell carcinoma. Tumors ap-peared as round with diameter 1.5 to 3.8 cm,… 相似文献
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Adamska A Nikołajuk A Karczewska-Kupczewska M Kowalska I Otziomek E Górska M Strączkowski M 《Acta diabetologica》2012,49(1):17-24
Insulin resistance might be associated with an impaired ability of insulin to stimulate glucose oxidation and inhibit lipid
oxidation. Insulin action is also inversely associated with TNF-α system and positively related to adiponectin. The aim of
the present study was to analyze the associations between serum adiponectin, soluble TNF-α receptors concentrations and the
whole-body insulin sensitivity, lipid and glucose oxidation, non-oxidative glucose metabolism (NOGM) and metabolic flexibility
in lean and obese subjects. We examined 53 subjects: 25 lean (BMI < 25 kg × m−2) and 28 with overweight or obesity (BMI > 25 kg × m−2) with normal glucose tolerance. Hyperinsulinemic euglycemic clamp and indirect calorimetry were performed. An increase in
respiratory exchange ratio in response to insulin was used as a measure of metabolic flexibility. Obese subjects had lower
insulin sensitivity, adiponectin and higher sTNFR1 (all P < 0.001) and sTNFR2 (P = 0.001). Insulin sensitivity was positively related to adiponectin (r = 0.49, P < 0.001) and negatively related to sTNFR1 (r = −0.40, P = 0.004) and sTNFR2 (r = −0.52, P < 0.001). Adiponectin was related to the rate of glucose (r = 0.47, P < 0.001) and lipid (r = −0.40, P = 0.003) oxidation during the clamp, NOGM (r = 0.41, P = 0.002) and metabolic flexibility (r = 0.36, P = 0.007). Serum sTNFR1 and sTNFR2 were associated with the rate of glucose (r = −0.45, P = 0.001; r = −0.51, P < 0.001, respectively) and lipid (r = 0.52, P < 0.001; r = 0.46, P = 0.001, respectively) oxidation during hyperinsulinemia, NOGM (r = −0.31, P = 0.02; r = −0.43, P = 0.002, respectively) and metabolic flexibility (r = −0.47 and r = −0.51, respectively, both P < 0.001) in an opposite manner than adiponectin. Our data suggest that soluble TNF-α receptors and adiponectin have multiple
effects on glucose and lipid metabolism in obesity. 相似文献
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Dhir Sangeeta Bansal Sumidha Wangnoo Subhash Jana DebarshI 《International journal of diabetes in developing countries.》2022,42(3):543-551
International Journal of Diabetes in Developing Countries - Periodontitis is a chronic inflammatory disease caused by pathogenic dental plaque which causes microbial dysbiosis leading to... 相似文献
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Michael V. Holmes Iona Y. Millwood Christiana Kartsonaki Michael R. Hill Derrick A. Bennett Ruth Boxall Yu Guo Xin Xu Zheng Bian Ruying Hu Robin G. Walters Junshi Chen Mika Ala-Korpela Sarah Parish Robert J. Clarke Richard Peto Rory Collins Liming Li Zhengming Chen 《Journal of the American College of Cardiology》2018,71(6):620-632
Background
Blood lipids are established risk factors for myocardial infarction (MI), but uncertainty persists about the relevance of lipids, lipoprotein particles, and circulating metabolites for MI and stroke subtypes.Objectives
This study sought to investigate the associations of plasma metabolic markers with risks of incident MI, ischemic stroke (IS), and intracerebral hemorrhage (ICH).Methods
In a nested case-control study (912 MI, 1,146 IS, and 1,138 ICH cases, and 1,466 common control subjects) 30 to 79 years of age in China Kadoorie Biobank, nuclear magnetic resonance spectroscopy measured 225 metabolic markers in baseline plasma samples. Logistic regression was used to estimate adjusted odds ratios (ORs) for a 1-SD higher metabolic marker.Results
Very low-, intermediate-, and low-density lipoprotein particles were positively associated with MI and IS. High-density lipoprotein (HDL) particles were inversely associated with MI apart from small HDL. In contrast, no lipoprotein particles were associated with ICH. Cholesterol in large HDL was inversely associated with MI and IS (OR: 0.79 and 0.88, respectively), whereas cholesterol in small HDL was not (OR: 0.99 and 1.06, respectively). Triglycerides within all lipoproteins, including most HDL particles, were positively associated with MI, with a similar pattern for IS. Glycoprotein acetyls, ketone bodies, glucose, and docosahexaenoic acid were associated with all 3 diseases. The 225 metabolic markers showed concordant associations between MI and IS, but not with ICH.Conclusions
Lipoproteins and lipids showed similar associations with MI and IS, but not with ICH. Within HDL particles, cholesterol concentrations were inversely associated, whereas triglyceride concentrations were positively associated with MI. Glycoprotein acetyls and several non–lipid-related metabolites associated with all 3 diseases. 相似文献7.
Thromboelastography (TEG), which records the continuous profiles of whole blood (WB) coagulation, can be used to evaluate the effects of hemostatic agents, such as recombinant factor VII (rFVIIa). Our group has developed a revised TEG model, involving activation with minute amounts of tissue factor and subsequent signal processing, and has used this method to evaluate the effects of rFVIIa both in patients with hemophilia and in those receiving vitamin K antagonist (VKA) thromboprophylaxis. We review the early results of our investigations, which suggest that, in clinical situations where rFVIIa has shown benefit, the changes in the profiles obtained by TEG recording appear to correlate with the clinical outcome. 相似文献
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谢大任 《国外医学:内科学分册》1982,(3)
Life is made up of exercise and activity;but,if life is to continue for any extended time,there must also be rest and relaxation.A bal-ance between activity and rest is the objectiveof all intelligent living-not too much activity,yet not too much rest.Life for most people is a very unbalancedaffair.Jobs in modern industry are so special-ized that usually one part or one set of organsof the body is overstrained while others arealways in need of exereise.Much of the fatigue and strain from thework we do today is the result of unnecessarytension.Every job we do requires that certain 相似文献
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《China Medical Abstracts (Internal Medicine)》2020,(1):20-28
2020036 Comparative analysis of clinical features of fulminant type 1 diabetes.WANG Yajing(王雅静),et al.Dept Endocrinol,1st Med Center,Chin PLA General Hosp,Beijing 100853.Med J Chin PLA 2019;44(11):937-94.Objective To analyze and compare the clinical features of fulminant type 1 diabetes mellitus(FT1D M). 相似文献
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Objectives To study the relationship between alcohol and atherosclerosis (AS). Methods The paper reviewed the mechanism of the alcohol leading to AS from four aspects such as the introduction of alcohol and AS, imbalance of oxidationantioxidation system, oxygen free radical (OFR) and endothelium cell (EC) apoptosis, apoptosis and AS. Results Excessive alcohol could lead to imbalance of oxidation-antioxidation system, and increase OFR, in the meanwhile, OFR could lead to EC apoptosis, which could lead to AS. 相似文献
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Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication. This list is provided as a service to readers; inclusion does not imply endorsement by the HBPD INT.Section editorShui-Ying LeiEmail: hbpdje@mail.hz.zj.cn 相似文献
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<正>Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication. This list is provided as a service to readers; inclusion does not imply endorsement by the Hepatobiliary & Pancreatic Diseases International. 相似文献
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Crohn’s and colitis in children and adolescents 总被引:1,自引:0,他引:1
Andrew S Day Oren Ledder Steven T Leach Daniel A Lemberg 《World journal of gastroenterology : WJG》2012,18(41):5862-5869
Crohn’s disease and ulcerative colitis can be grouped as the inflammatory bowel diseases (IBD). These conditions have become increasingly common in recent years, including in children and young people. Although much is known about aspects of the pathogenesis of these diseases, the precise aetiology is not yet understood, and there remains no cure. Recent data has illustrated the importance of a number of genes-several of these are important in the onset of IBD in early life, including in infancy. Pain, diarrhoea and weight loss are typical symptoms of paediatric Crohn’s disease whereas bloody diarrhoea is more typical of colitis in children. However, atypical symptoms may occur in both conditions: these include isolated impairment of linear growth or presentation with extra-intestinal manifestations such as erythema nodosum. Growth and nutrition are commonly compromised at diagnosis in both Crohn’s disease and colitis. Consideration of possible IBD and completion of appropriate investigations are essential to ensure prompt diagnosis, thereby avoiding the consequences of diagnostic delay. Patterns of disease including location and progression of IBD in childhood differ substantially from adult-onset disease. Various treatment options are available for children and adolescents with IBD. Exclusive enteral nutrition plays a central role in the induction of remission of active Crohn’s disease. Medical and surgical therapies need to considered within the context of a growing and developing child. The overall management of these chronic conditions in children should include multi-disciplinary expertise, with focus upon maintaining control of gut inflammation, optimising nutrition, growth and quality of life, whilst preventing disease or treatment-related complications. 相似文献
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<正>Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication. This list is provided as a service to readers; inclusion does not imply endorsement by the Hepatobiliary & Pancreatic Diseases International. 相似文献
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Announcements for this section should be submitted in the correct format at least 3 months before the required 相似文献
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Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication. This list is provided as a service to readers; inclusion does not imply endorsement by the HBPD INT.Section editor Shui-Ying Lei Email: hbpdje@mail.hz.zj.cnFebruary, 2007 2007 pancreas cancer February 21-23, 2007; Rome, Italy Pancreas Cancer 2007 will be a meeting point where different diagnostic and therapeutic modalities are examined, focusing on recent ad… 相似文献
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Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication.This list is provided as a service to readers;inclusion does not imply endorsement by the Hepatobiliary&Pancreatic Diseases International. 相似文献
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4.1.Autoimmune disease2005303 Peripheral blood mRNA and interferongene expression in systemic lupus erythematosus.TANG Jianping(汤建平),et al.Dept Rheumatol,RenjiHosp,Shanghai 2nd Med Univ Shanghai 200001.Chin JIntern Med 2005;44(2):106-110. 相似文献
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2005216 Safety of Helicobacter pylon 'test-and-treat' strategies for the management of uninvestigated dyspepsia. LI Xiao-bo(李晓波),et al. Gastroen-terol, Shanghai Instit Dig, Renji Hosp, Shanghai 2nd Med Univ, Shanghai 200001. Chin J Med, 2005; 44(3):195-197. Objective: To verify the safety of Helicobacter pylori (Hp) 'test-and-treat' and 'test-and-endoscopy' strategies for management of uninvestigated dyspep- 相似文献