微博对大学生心理健康及社交影响分析

微博,是一个基于用户关系信息分享、传播以及获取的平台,用户以140字左右的文字更新信息,并实现即时分享。微博传播速度的即时性、传播内容的自主性、传播方式的互动性对网络用户产生了巨大的吸引力。据电商数据显示,截至2012年12月31日,仅新浪微博用户就达5．03亿,可见微博在我国人群中使用的普遍性。据王亚煦等人的调研数据显示,97％的大学生正在使用微博;而未开通微博的大学生中,有38％的人表示准备使用,微博已经成为我国大学生群体进行资讯传播和网络社交的一种重要媒介。     

新型冠状病毒肺炎疫情期大学生网络健康信息搜寻行为调查分析

目的调查新型冠状病毒肺炎(COVID-19)流行期大学生群体网络相关信息获取现状，分析其行为特征和影响因素，为完善大学生疫情信息服务工作、制定其自我教育与管理措施提供参考依据。方法通过网络问卷收集相关数据，对709份有效问卷进行统计分析。结果大学生群体网络信息搜寻频率集中在每天1～5次，最关注内容为疫情新闻，主要渠道是微博、微信等社交软件。女性、月生活费较高者的搜寻频率较高，行为意图、电子健康信息素养对搜寻频率也有正向影响。结论大学生普遍对COVID-19疫情十分关注，微博、微信等社交软件是其获取相关信息的重要途径，提示相关部门应加强微博、微信等平台的COVID-19信息质量监控。另外，COVID-19疫情背景下影响健康信息搜寻的因素相较于一般健康信息搜寻的影响因素，其研究结果存在差异，疫情背景的特殊性是主要原因。     

大学生在校学习时间与亚健康状况的相关性分析

目的：调查分析大学生在校学习时间与亚健康状态的关系。方法：使用亚健康状况评定量表对930名医学专业大学生进行调查问卷。结果：医学专业大学生中亚健康发生率达86．88％,大学生亚健康与学习时间相关系数为0．5532,呈正相关。结论：大学生亚健康状态和学习时间存在正相关性,应关注大学生群体的心理及需求,提高这一群体的自我保健意识。     

利用微博构建大学生思想政治教育的新路径

当前,微博因其即时性、自主性、便捷性等特征,赢得了广大大学生的喜爱,成为大学生获取信息和人际沟通的一种重要方式和渠道,这也给大学生思想政治教育工作带来了新的挑战,如大学生思想政治教育内容的主导性不突出、工作方法不合时宜、主客体间缺乏互动性等。利用微博开展大学生思想政治教育,有很多优势,它丰富了大学生思想政治教育的内容和形式,增强了大学生思想政治教育工作的时效性和有效性,增加了大学生思想政治教育双方的交互性。高校应与时俱进,加强队伍建设,提供教育保障;搭建校内平台,繁荣网络文化;加强内容建设,强化舆论引导;给予激励,促进微博教育长效发展。     

信阳市2 281名大学生群体无偿献血相关KAP水平现况调查及影响因素分析

目的 探讨市大学生群体无偿献血相关知信行(Knowledge,Attitude,Practice,KAP)水平现况及影响因素。方法 以多级抽样方法从市4所高校抽取2 281名大学生(2019年1月～2019年12月)作为研究对象,自制KAP水平调查问卷,调查其无偿献血相关KAP水平,并分析影响KAP水平的因素。结果 2 281名大学生群体无偿献血知识得分为(4.71±1.66)分,有无偿献血意愿的650名,占28.50%,有无偿献血行为的579名,占25.38%;不同年级、专业的大学生群体无偿献血知识得分比较差异显著(P＜0.05),不同性别、父母文化水平的大学生群体无偿献血知识得分比较无明显差异(P＞0.05);不同性别、专业的大学生群体无偿献血意愿比较差异显著(P＜0.05),不同年级、父母文化水平的大学生群体无偿献血意愿比较无明显差异(P＞0.05);不同性别、专业、父母文化水平的大学生群体无偿献血行为比较差异显著(P＜0.05),不同年级大学生群体无偿献血行为比较无明显差异(P＞0.05);经Logistic多因素分析得知,年级低、非医学类专业为影响大学生群体无偿献血知识的危险因素,女性、非医学类专业为影响大学生群体无偿献血态度的危险因素,女性、非医学类专业、父母文化水平低为影响大学生群体无偿献血行为的危险因素(P＜0.05)。结论 市大学生群体无偿献血相关KAP水平现况不容乐观,受到专业、年级、父母文化水平、性别等因素影响,应采取针对性干预措施,提高KAP水平。     

大学生脆弱群体与普通群体身心健康的比较研究

目的：比较分析大学生脆弱群体和普通群体心理健康相关因素的差异,为提高大学生脆弱群体的心理健康水平提供科学依据。方法：采用临床症状自评量表（SCL-90）和自编部分,随机抽取绍兴市某高校200名学生进行问卷调查,资料整理后进行统计分析。结果：脆弱群体与普通群体在生源地、家庭收入、家庭成员关系、心理压力和压力来源上有统计学差异（P〈0.05）。结论：应重点关注大学生脆弱群体,努力提高其心理健康水平。     

医院有多少“微博控”

随着网络的普及、互联网用户群体的不断壮大,论坛、微博、即时通讯软件、社交网站等社会化媒体形态正在被广泛地使用。据不完全统计,截至目前,中国内地已有100多家大型综合医疗机构开通了官方微博,1000多名知名专家使用微博与网民互动交流。部分医生还通过微博帮助有特殊困难的患者预约挂号。     

我国“90后”大学生心理健康研究述评

“90后”大学生指的是出生于20世纪90年代并且目前已进入大学的中国公民?研究表明,“90后”大学生心理健康的总体状况良好,并不比“80后”大学生差;关于“90后”大学生心理健康的性别?年级和城乡差异,目前还未形成一致的结论?影响“90后”大学生心理健康的因素主要有人格特征?应对方式?自我同一性等个体因素以及家庭?学校?社会等环境因素?未来的研究中,在研究内容上应更多关注“90后”大学生的积极心理;在研究对象上应更多关注不同类别“90后”大学生的心理健康;在研究方法上应整合使用访谈法?测验法和实验法等方法     

医学生对安全套认知现状调查分析

O 引言 大学生作为性成熟群体,其不安全性行为已引起社会各界的关注与担忧.近年来,有学者对非医学专业大学生使用安全套的情况进行调查[1-2],结果不容乐观.     

武汉市大学生健康知识知晓情况调查

目的：通过调查,了解武汉市大学生群体对健康知识的知晓情况。方法：采用自行设计的调查问卷,随机抽取武汉市4所高校的420名在校大学生,进行问卷调查并对结果进行统计学分析。结果：武汉市大学生对健康知识知晓率较低;女生组好于男生组;医学生组明显好于非医学生组。结论：武汉市大学生的健康知识知晓情况较差,应根据不同专业和不同性别分别采取相应措施加以改善。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.