武汉地区2886名健康人骨矿含量变化规律的研究

对武汉地区3～89岁2886名健康人进行了桡、尺骨骨矿含量的测定。发现出生后骨矿含量随增龄而逐渐升高,5～8岁是儿童增长的第一个高峰期,13～16岁是第二个高峰。20岁以后同年龄组性别不同,骨矿含量差异显著,女性普遍低于男性。男、女均于30～39岁时达到峰值骨量,以后随增龄骨矿含量逐渐下降,50岁以后女性受绝经后卵巢功能减退的影响,骨矿含量下降迅速。经常从事体育锻炼的人比同龄无运动习惯的人具有较高的骨矿含量。     

山东地区健康中老年人桡、尺骨骨矿含量的调查

测定了山东地区１６８２名健康中老年人左侧桡、尺骨的骨矿含量（ＢＭＣ），男性峰值骨量在４０～４９岁年龄组，女性在３０～３９岁年龄组；男、女ＢＭＣ均随年龄增长而逐渐降低，女性下降的程度高于男性且与绝经年限密切相关；ＢＭＣ还与职业、吸烟、饮酒、运动有关，骨质疏松症患病率男为１５．２％，女为２４．８％。     

中老年妇女骨矿含量的影响因素和骨质疏松发病调查

使用单光子骨矿含量测量仪，检测了重庆地区４０～８８岁１０６０例妇女挠骨骨矿物质含量（简称ＢＭＣ）。４０岁以上中老年妇女骨矿含量随年龄老化呈持续性减少，绝经加速了骨矿的丢失。骨矿含量与年龄、绝经年限呈显著性负相关（ｒ＝－０．５３７、－０．４５６．Ｐ均＜０．０１）．与身高、体重、孕次、产次无相关性。职业对ＢＭＣ无显著影响，运动是ＢＭＣ的保护因素。本地区中老年妇女骨质疏松发病率为３８．８％，其中未绝经组发病率仅为３．６％，而绝经后骨质疏松则为４３．５％，７０～８８岁的老年妇女８５％存在骨质疏松。     

湖北省荆州市市区208位成年女性骨矿含量测定

目的：了解湖北省荆州市健康妇女骨矿含量．方法：对本市区20～93岁，208例社区妇女（已绝经妇女122人），用SD—200型骨矿测量仪（单光子吸收测量，光源为镅），测定非优势手中下1／3处线骨矿含量（BMC）、面骨矿含量（BMD），骨皮质指数（骨皮质厚／骨宽度）．结果：骨峰值在30－39岁组、40～49岁组的骨矿含量下降，50～59岁骨矿含量为峰值期的3／4，80岁以后骨矿含量下降51．93％，骨皮质指数亦随年龄下降，60岁以后尤为明显．结论：40岁以后女性特别是老年妇女，防治骨质疏松症十分重要．     

80岁以上老年人的骨矿含量变化

本文对70例80岁以上老年人进行桡、尺骨骨矿含量测定,并与50～60岁老年前期的骨矿含量对照分析如下。材料与方法一、对象:年龄80岁以上老年人70例,其中男20例,女50例。对照组:50～60岁374人,其中男性217人,女性157人。所有对象均已排除影响骨代谢的各种慢性疾病。二、方法:     

山东地区健康中老年人桡,尺骨骨矿含量的调查

测定了山东地区１６８２名健康中老年人左侧桡、尺骨的骨矿含量（ＢＭＣ），男性峰值骨量在４０￣４９岁年龄组，女性在３０￣３９岁年龄组；男、女ＢＭＣ均随年龄增长而逐渐降低，女性下降的程度高于男性且与绝经年限密切相关；ＢＭＣ还与职业、吸烟、饮酒、运动有关，骨质疏松症患病率男为１５．２％，女为２４．８％。     

宁夏银川地区280例老年人骨矿含量测定分析

采用ＳＤ－１００型骨矿物测定仪测定银川地区２８０例老年人尺桡骨矿含量。结果表明：男性骨矿含是显著高于女性；骨矿含量随年龄的增大逐渐降低，绝经年限越长的妇女其骨矿含量越低；骨矿含量与运动和饮食习惯密切相关，本组老年性骨质疏松发生主为２１．１％，其中女性是男性的３．７５倍。     

石河子地区正常成人骨矿含量调查分析

目的：为研究人群中各矿含量的变化规律,确定不同性别、不同年龄段骨矿含量的正常值,方法：采用单光子吸收法对石河子地区1013名汉族健康成人桡、尺骨骨矿含量测定。结果：30岁以前骨矿含量随年龄增长而增长,30-39岁年龄段达峰值骨量,40岁以后骨矿含量呈逐渐降低趋势,女性50岁以后骨密度明显降低,结论：首次建立了我区不同性别、不同年龄段的正常人桡、尺骨骨密度的正常参考值。     

绝经前后妇女骨矿含量正常值的探讨

运用单光子吸收法对761名正常妇女桡骨的两处进行了骨矿含量的测量。以5岁为一年龄组进行了统计学分析,显示女性在35岁～组后骨矿含量随年龄增长而降低。绝经期妇女的骨矿含量呈全骨性降低。60岁～组后,骨矿含量降低又趋缓慢。结果表明妇女的骨矿含量在绝经期降低尤为显著。为了及时发现绝经期骨质疏松症病人,最好建立每岁的正常骨矿含量标准,但目前尚无,本文建立以5岁为一年龄组的正常骨矿含量标准可为临床诊断骨质疏松症提供依据,并建议对绝经期妇女应每年监测骨矿含量。     

呼和浩特市老年人骨矿含量测定及钙磷变化分析

用中国科学院东方仪器设备公司生产的SD-100型骨矿物仪和美国实验仪器公司生产的Monarch全自动高级生化分析仪,对76例年龄60～81岁的老年人(男58例,女18例)进行了骨矿含量和血钙、磷、碱性磷酸酶测定。并与40例20～40岁青壮年(男28例,女12例)连行比较。结果表明青壮年男、女的骨面密度明显高于老年组,两者差异非常显著(P<0.01);老年男性骨面密度高于同龄女性(P<0.01)。血钙含量老年男女均较青壮年组低,经统计学处理,男性差异显著(P<0.01);女性不显著(P>0.05)。血磷测定结果两组无明显差异(P均>0.05)。     

昆明地区2156例正常人骨矿物质含量调查

报道昆明地区1—91岁2156例正常人(男1079人,女1077人)尺桡骨矿含量(BMC)调查,结果:(1)BMC 30岁前上升,30—39岁在高峰,40岁后下降,尺、桡骨矿水平无显著差异。(2)从16岁开始,女性BMC显著低于男性,50岁以后两性差异更显。(3)青春期骨矿加速增长,女早于男,平均年增7.38％,男后来居上,年增10.69％。(4)女性绝经以后骨盐丢失加快,平均每年丢失0.83％,是男性0.27％的三倍。(5)75岁以后,女性保留骨量占峰值的74.78％,男性保留占89.14％％,差异非常显著.(6)BMC与身高、体重呈线性正相关。     

髋部骨折与骨质疏松的临床探讨

本组治疗的髋部骨折１２０例，其中男５２例，女６８例。年龄在５１岁以上者有１０４例占８３．６％，全部病人进行髋部Ｘ线片骨小梁测量及骨矿物含量测定。结果证明，骨折病人骨小梁减少，骨皮质变薄，与比较组二者之间骨密度含量有明显差别，本病治疗上庆急取患者早期离床活动，避免骨质继续丢失，减少并发症，对提高患者身体素质和减轻社会负担有着积极的临床意义和社会影响。     

COMPARISON OF BONE MASS IN FOREARM, LUMBAR VERTEBRA AND HIP BY SINGLE AND/OR DUAL ENERGY X-RAY ABSORPTIOMETRY

Objective. Bone mineral density(BMD) was measured in normal Chinese women with single X-ray sbsorptiometry (SXA) and dtml energy X-ray absorptiometry (DEXA). These two methods were compared to evaluate the sensitivity in reflecting bone loss. Methods. Measurements were performed in 300 women aged 20～79(5 for each age). The 8mm distal,1/4 distal, ultra distal site ot the nondominant torearrn were measured with SXA; the AP spine(L2-4), right femoral neck(Neck), Ward‘s triangle(Ward)and trochantor (Troch) were measured with DEXA. Ten wcanen had 5 repeated measurements to evaluate the reproducibility ot the equipments. Rgsults. The BMD peak for Neck and Ward was found between age 20～29, for ultra distal and L2-4 at age 30～39, for 8mm distal, 1/4 distal and Troth at age 40～49. After reaching the peak values, BMD at all sites decreased with increasing age. The highest rate of yearly loss of BMD was at 8ram distal. Resuits of measurement showed siguifieant correlation between SXA and DEXA. Comparing with premenopausal women, the bone loss rate in postnaenopausal women was faster and highest up to 11～15 years and the highest rate was at the Ward. Conclusion. The present study gives the normal values of BMD at seven sites for nccmal Chinese wonaen. The ages of BMD peak were different at seven sites. The yearly loss of BMD was highest at 8ram distal, it seemed to be the sensitive region for bone loss with age. The postmenopansal women had highly signiflcantly loss bone mass than the premenopausal women, Comparing with premenopause, postmenopsuse BMD for Ward‘s triangle with DEXA seemed to be most sensitive to the effect of menopause.     

甲亢患者骨矿物质含量变化及有关因素的探讨

本文以单光子骨密度仪测定30例甲亢患者的BMC,BMD,并以相应年龄、性别的正常人作对照,同时测定患者的血钙、血磷、AKP、24小时尿钙和尿磷,结果显示男、女性患者均有BMC、BMD的降低,绝经的患者更为明显,BMC与血清钙,BMD与尿钙均呈正相关关系,单光子骨密度仪测定骨矿物质含量对研究甲亢性骨病具有重要意义。     

Measurement of bone mineral content in vivo using photon absorptiometry

Progress in evaluating treatment of systemic bone disease has been hampered in the past by lack of precise in vivo quantitative techniques. Recently a method has been developed for measurement of bone mineral content (BMC), based on bone absorption of low-energy monochromatic radiation. This paper discusses a technique of photon absorptiometry using ¹²⁵l as a collimated point source. The technique is simple, with accuracy and precision within 2%.

BMC and bone width (W) were measured in the distal radius of 359 normal subjects ranging in age from 5 to 82 years. A “normal” curve of BMC/W with age as the independent variable was then obtained from this population and was constructed for each sex. A positive correlation of BMC/W with height and body weight was found in a group of normal males.

A series of patients with osteoporosis or malabsorption, or undergoing hemodialysis or steroid treatment, was then assessed in order to demonstrate changes in BMC/W that may occur secondary to disease or disturbances in calcium metabolism. Many of these patients were found to have a BMC/W below the normal mean value for their age and sex.