医学F1000推荐文献的来源期刊分布

利用PubMed和SCI数据库对F1000推荐的文献进行分析的结果表明,被PubMed收录的F1000推荐文献的来源期刊比较集中,其中18种期刊占据了全部F1000推荐文献的44.72%,来源期刊98%以上被JCR收录,但F1000推荐的文献数量较少,尤其是临床方面的文献更少。因此F1000推荐的文献虽然比较重要,但仅可作为参考。     

2007年上海交通大学SCI医学论文列全国第二

2008年12月9日，中国科学技术信息研究所在北京召开2007年度中国科技论文统计结果发布会。数据显示，在2007年SCI收录论文较多的高校中，上海交通大学收录文献2485篇（论文数2331篇），名列全国高校第三位；其中按医学学科分类收录论文421篇，首次居全国第二，比上年度（243篇）增长73％，论文数量明显提升，扩大了在国内外学术界的影响力。     

F1000对医学期刊被引情况的影响

目的:研究F1000在医学领域对文献被引用情况的影响。方法: 检索F1000数据库, 将2006-2008年第4年被F1000推荐的文献作为研究对象,在相同时间段选择发表后即可被推荐和从未被推荐的文献作为第一对照组和第二对照组,检索Web of Science,获得三组文献在发表后第1-6年的被引数量,研究三组文献在6年内的被引趋势;将所得数据重新组合为发表后前3年、后3年和总被引次数,利用SPSS 11.0软件对各组数据做配对t检验。结果：研究文献在发表后的第4年达到被引用峰值,而第一和第二对照组均在第3年达到被引用峰值;配对t检验显示,研究组文献与第一对照组和第二对照组之间被引用次数在发表后前3年未见显著差异,而在后3年存在显著差异,总被引次数也表现出显著差异。结论：F1000在医学领域对人们的引证行为产生了显著影响。     

PubMed与Embase收录中国生物医学期刊及标引质量分析

目的：比较分析PubMed与Embase收录中国生物医学期刊及其文献标引质量。方法：从重复收录、元数据字段分析PubMed与Embase收录中国生物医学期刊情况,从标引字段、标引深度、标引差异性比较其文献标引质量。结果：PubMed收录的中国生物医学期刊自身元数据描述有29个字段,文献数据标引有47个字段,篇均主题词标引深度为11.12;Embase收录的中国生物医学期刊自身元数据描述有13个字段,文献数据标引有44个字段,篇均主题词标引深度为14.13。结论：PubMed对其收录的中国生物医学期刊自身元数据的描述更详细,Embase对收录的中国生物医学期刊文献主题标引的粒度更细、数量更多、标引更规范。二者对中国生物医学文献的标引较之对外文文献的标引一致性较高。     

我校科技论文排名取得可喜进步

根据中国科学技术信息研究所2006年10月27日公布的统计结果,2005年度我校共有1933篇论文在1652种统计源期刊上发表,名列全国高校第27位,比去年又前进了3位;被《SCIE》收录论文121篇(文献类型:Article、Review、Letter),名列全国高校第81位,并荣获2005年度《SCI》收录医学论文数     

《北京中医药大学学报》论文被SCIE引用情况分析

目的通过对《北京中医药大学学报》(以下简称《学报》)论文被美国《科学引文索引》扩展版(SCIE)收录的期刊论文引用情况进行定量分析,为《学报》发展提供相关参考依据。方法以Web of Science核心合集数据库为依据,在被引参考文献检索中,检索并分析《学报》论文被SCIE引用的情况及施引文献情况。结果 1995—2018年间,《学报》论文共有556篇在SCIE中被引用,总被引频次为879次,被引数量和被引频次均呈现抛物线状的趋势。施引文献共773篇论文,其年度分布总体呈上升趋势。被引论文第一作者机构主要为北京中医药大学。国家级基金资助课题的论文占比最高。被引频次高于5次的10篇论文分布在"科技之窗"栏目5篇、"理论研究"栏目4篇、"中医药实验研究"1篇。引用《学报》论文的期刊总体处于国际中等水平,结合补充医学、药理学和药剂学以及化学3个研究方向的引用论文最多。结论《学报》被SCIE收录期刊论文引用仅占总载文量的8.7%,在国内虽然有较高影响力,但国际影响力明显较低。"理论研究""科技之窗"栏目中的论文受关注度最高,可作为优势栏目保持并强化;可重点加强补充医学、药理学和药剂学以及化学这几个研究方向的组稿力度,并创新优化组稿,提升期刊影响力。     

《武警后勤学院学报(医学版)》影响因子继续提高

近年来,《武警后勤学院学报(医学版)》按照学院领导和编委会的要求,以作者队伍和审稿专家队伍建设为重点,不断加强期刊内涵建设,刊物的质量和学术影响力稳步提升。在中国科学技术文献评价研究中心近期发布的2014年版《中国学术期刊影响因子年报(自然科学与工程技术)》中,《武警后勤学院学报(医学版)》(影响因子0.371)在全国被收录的202种综合性医药卫生期刊中综合排名第79位。《中国学术期刊影响因子年报(自然科学与工程技术)》是由中国科学文献计量评价研究中心与清华大学图书馆共同研制,经《中国学术期刊(光盘版)》电子杂志社按年度连续出版的电子期刊。     

交叉边缘跨学科科技期刊的评价及归类

介绍了医学F1000因子的概念和计算公式,选取医学F1000网站部分文献,通过其F1000因子与其所在期刊影响因子的比较,发现医学F1000与影响因子在评价对象、评价方法、组织文献方法等方面的不同,建议在评价文献质量时应综合应用这两项指标。     

国内医学PBL教学文献计量分析

利用文献计量学方法,对1994-2010中国学术期刊网络出版总库收录的1 092篇医学PBL教学论文进行分析,揭示其文献年度增长、机构分布、作者分布和期刊分布等特征和规律。     

中国科技论文统计源期刊(中国科技核心期刊)收录证书

同济大学学报医学版经过多项学术指标综合评定及同行专家评议推荐,贵刊被收录为"中国科技论文统计源期刊"(中国科技核心期刊)。特颁发此证书。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.