临床护理路径预防颅内多发动脉瘤围手术期并发症的临床效果

目的探讨临床护理路径预防颅内多发动脉瘤围手术期并发症的效果。方法选择颅内多发动脉瘤患者100例,随机分为观察组和对照组各50例。对照组给予常规护理,观察组给予临床护理路径,比较护理干预后2组并发症发生率及护理满意度,并采用生活质量综合评估问卷(GQOL-74)评估患者生活质量。结果干预后观察组并发症的总发生率(10.0%)明显低于对照组(30.0%)(P0.05),GQOL-74评分明显优于对照组(P0.05),护理满意度(96.0%)明显高于对照组(80.0%)(P0.05)。结论临床护理路径可有效地减少颅内多发动脉瘤患者围手术期并发症的发生率,改善患者的生活质量,提高患者的护理满意度,值得临床推广与应用。     

人性化护理在颅内动脉瘤围手术期的应用观察

目的观察人性化护理在颅内动脉瘤围术期的临床应用效果。方法选取2010-01—2014-01我院收治的颅内动脉瘤手术患者152例,按入院顺序分成观察组和对照组,每组76例,对照组实施脑外科常规护理,观察组在此基础上实施人性化护理干预,观察比较2组术后生活质量评价、并发症发生率及护理满意度等指标。结果观察组生活质量SF-36各维度评分明显高于对照组;观察组并发症(10.38%)发生率明显低于对照组(28.57%);观察组护理满意度(97.37%)明显高于对照组(81.58%),差异均有统计学意义(P0.05)。结果对颅内动脉瘤患者实施围手术期人性化护理干预,可减少患者围术期并发症,提高术后生活质量和护理满意度,有效提升护理质量。     

人性化护理在颅内动脉瘤血管内栓塞术围手术期的应用

目的探讨人性化护理在颅内动脉瘤血管内栓塞术围手术期应用效果。方法收集2016-01—2018-01入院的80例颅内动脉瘤血管内栓塞术患者,随机分为2组,对照组给予常规护理,观察组则加施人性化护理,比较2组患者心理状况、围手术期生理指标与远期生活质量。结果观察组干预后与出院前SAS评分与SDS评分组间比较均显著性低于对照组;术前30min收缩压、舒张压、呼吸频率与心率水平组间比较均显著低于对照组;术后1个月与末期随访疼痛、娱乐消遣与咀嚼维度评分组间比较均显著性低于对照组,差异有统计学意义(P0.01);术后总并发症发生率明显低于对照组,差异有统计学意义(P0.05)。结论人性化护理在颅内动脉瘤血管内栓塞术围手术期应用效果显著。     

老年患者颅内破裂动脉瘤血管内介入治疗的护理

目的研究早期护理干预在颅内破裂动脉瘤老年患者实施血管内介入治疗过程中的应用效果。方法将河南科技大学第二附属医院于2016-02-2017-01收治56例颅内动脉瘤破裂老年患者,按照入院先后顺序划分为对照组与观察组各28例,对照组接受常规术期护理服务,观察组接受临床提供的早期护理干预服务,总结2组术后并发症发生率,采用格拉斯哥预后量表(GOS)评估患者预后,评估患者生活质量评分。结果对照组术后并发症发生率28.57%,观察组为7.14%,观察组发生率低于对照组(P0.05)。对照组恢复乐观所占比例低于观察组,轻度及重度致残比例均高于观察组(P0.05)。对照组肢体功能、日常活动能力、家庭融入度及心理情绪等评分均低于观察组(P0.05)。结论科室为老年论颅内动脉瘤破裂患者提供早期护理干预,可有效降低术后并发症发生率,促进患者恢复,改善生活状态。     

伦理护理干预在颅内转移瘤患者围手术期中的应用

目的分析伦理护理干预在颅内转移瘤患者围手术期的应用效果。方法选取我院收治的100例颅内转移瘤患者为研究对象,按随机数字表法分为对照组与观察组各50例。对照组采用常规护理方案,观察组在对照组基础上加用伦理护理干预,采取生活质量评估量表统计干预前后患者生活质量的改善情况,观察2组术后并发症发生率,采取焦虑及抑郁评分表评估干预前后2组心理状况的改善情况。结果护理前2组不同维度生活质量评分、焦虑、抑郁量表评分比较无显著差异(P0.05),护理后,观察组精神状态、躯体功能、心理状态及整体健康评分分别上升至(55.8±4.7)分、(49.7±5.2)分、(60.4±2.6)分、(63.7±4.4)分,观察组焦虑、抑郁量表评分降低至(12.1±5.2)分、(11.7±6.4)分,与对照组相比差异有统计学意义(P0.05);观察组并发症发生率8.0%,与对照组的28.0%比较差异有统计学意义(P0.05)。结论在颅内转移癌患者围手术期护理干预中,贯彻伦理原则,尊重、关爱患者,对改善其生活质量、心理负性情绪有积极的价值,同时可降低术后并发症发生率,值得推广。     

原发性面肌痉挛行面神经毁损术的围手术期护理

目的观察原发性面肌痉挛行面神经毁损术治疗的围术期护理效果。方法选取2015-03—2016-12在我院进行治疗的124例原发性面肌痉挛患者,均行面神经毁损术治疗,按照随机数字表法将其分为对照组和观察组各62例,对照组给予常规护理干预,观察组给予围术期综合护理干预,对比2组患者手术各项指标、术后并发症发生情况及护理满意度。结果对照组手术成功率为80.65%,观察组为95.16%,观察组手术成功率明显高于对照组,组间对比差异有统计学意义(P0.05);相较于对照组,观察组术后痉挛停止时间和住院时间均明显缩短,组间对比差异有统计学意义(P0.05);观察组并发症发生率明显低于对照组,组间对比差异有统计学意义(P0.05);观察组护理满意度明显高于对照组,组间对比差异有统计学意义(P0.05)。结论在原发性面肌痉挛行面神经毁损术治疗围手术期给予综合护理干预,可提高手术成功率,缩短术后痉挛停止时间和住院时间,且还有助于减少并发症,促进护理质量和护理满意度的提高。     

护理干预在艾滋病合并颅脑疾病患者围手术期的应用效果

目的探讨艾滋病合并颅脑疾病患者围手术期护理干预效果。方法选取我院2011-01—2016-12艾滋病合并颅脑疾病患者40例,按照入院顺序分为对照组和观察组,对照组采取常规护理;观察组实施综合性护理干预,干预30d后,比较2组患者满意度及并发症的发生情况。结果观察组护理满意度95%明显高于对照组的65%(P0.05);观察组并发症发生率25%明显低于对照组的70%(P0.05)。结论艾滋病合并颅脑疾病患者采取综合性护理干预,提高了护理满意度,有效减少了并发症发生,取得较好临床效果。     

脑动脉瘤破裂介入栓塞的治疗及围术期护理配合

目的探讨脑动脉瘤破裂患者实施介入栓塞治疗及围手术期的护理配合措施及具体效果。方法抽选2013-01-2014-02在我院就诊并接受介入栓塞治疗的脑动脉瘤破裂患者82例为研究对象,结合患者入院时间先后分为2组。对照组(41例)给予常规护理,观察组(41例)给予围手术期综合护理干预,护理人员在具体护理过程中遵从医嘱并提高护理措施的全面性、针对性以及主动性,统计2组患者手术成功率及护理满意度。结果观察组治疗有效率(92.7%)明显高于对照组(75.6%),差异有统计学意义(P0.05)。观察组护理满意度(95.1%)明显高于对照组(75.6%),差异有统计学意义(P0.05)。结论围手术期综合护理干预对提升脑动脉瘤破裂患者介入栓塞的治疗效果有重要作用,同时能显著提高患者护理满意度,值得临床推广。     

综合护理干预对颅内动脉瘤介入术后患者的影响

目的探讨综合护理干预对颅内动脉瘤介入术后患者的影响。方法选择2014-04—2015-08我院收治住院择期行介入术治疗的颅内动脉瘤患者94例,随机分为干预组及对照组,对照组采取常规护理措施,干预组在对照组基础上运用综合护理干预措施,比较2组干预前后心理状态、生活质量评分、术后并发症发生率及对护理工作的满意程度。结果干预前2组患者SAS、SDS评分差异无统计学意义(P0.05),干预后各评分均较干预前显著降低,且干预组显著低于对照组(P0.05);2组患者干预前SF-36各维度评分差异无统计学意义(P0.05),干预后2组患者各维度评分均显著升高,且干预组显著高于对照组(P0.05);干预组术后并发症发生率显著低于对照组(P0.05);干预组对护理工作总满意率显著高于对照组(P0.05)。结论综合护理干预有助于颅内动脉瘤介入术患者心理状态的改善,可提高患者生活质量,有效降低术后并发症发生率,促进患者康复,提高患者对护理工作的满意度,值得运用。     

ERAS在颅内动脉瘤显微夹闭术中的应用

目的 探讨快速康复外科（ERAS）理念在颅内动脉瘤夹闭术围手术期应用的安全性及有效性。方法 回顾性分析2017年1月至2018年12月显微夹闭术治疗的112例颅内动脉瘤的临床资料,根据护理方法分为ERAS组（60例）和对照组（56例）。对照组采用传统的围手术期处理方法,ERAS组应用ERAS优化措施进行围手术期管理。结果 ERAS组术后进食时间、下床活动时间、拆线时间、术后住院时间均较对照组明显缩短（P<0.05）。ERAS组术后并发症发生率（15.00%）明显低于对照组（42.31%;P<0.05）。ERAS组护理满意度（88.33%,53/62）明显高于对照组（67.31%,35/52;P<0.05）。结论 ERAS理念用于颅内动脉瘤显微夹闭术围手术期管理是安全有效的,能够减少术后并发症,缩短住院时间     

不同病房模式对精神分裂症病情影响的研究

目的探讨不同病房模式对首发精神分裂症患者病情的影响及康复情况。方法开放式病房的患者为研究组68例,同时选择住封闭式病房患者为对照组130例,对两组患者的临床资料进行比较分析。结果对照组患者入院时焦虑抑郁及敌对猜疑出现明显变化（P＜0.05）;研究组患者在第1周时焦虑抑郁已经开始改善,第2周时病情、阳性症状、一般精神病理、敌对猜疑、激活性也出现明显变化（P＜0.05）;第4周时研究组病情及各因子、认知功能及自知力显著改善,与对照组比较存在统计学差异（P＜0.05）。结论开放式病房模式可以减少患者的负性影响,更快改善患者的认知功能,有利于患者自知力的恢复,使患者的病情达到更全面的康复。     

Certain predictions on the effectiveness of l-DOPA on parkinsonism

Summary Sixty nine patients with Parkinson's disease were treated with L-DOPA for more than a year. L-DOPA produced remarkable improvement in akinetic patients, moderate improvement in rigidity and slight improvement in tremor. The degree of improvement in akinesia, rigidity and tremor tended to be reversely related to the severity of the disease. Rigidity and akinesia improved better in young patients, but there was no correlation between age and the response of tremor to the treatment. Except for rigidity there was no correlation between the improvement and the duration of the disease.

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Zusammenfassung 69 Parkinsonpatienten wurden während mehr als 1 Jahr mit L-DOPA behandelt. Es wurde dadurch bei akinetischen Patienten eine beachtliche, bei Patienten mit Rigor eine mäßige und bei Patienten mit Tremor eine geringfügige Besserung erreicht. Das Ausmaß der Besserung war in allen drei Formen um so geringer, je ausgeprägter die Symptome bei Behandlungsbeginn waren. Rigor und Akinesie sprachen bei jungen Patienten besser auf die Therapie an, aber es bestand keine Korrelation zwischen dem Alter der Patienten und der Beeinflußbarkeit des Tremors durch die L-DOPA-Therapie. Außer für den Rigor bestand keine Korrelation zwischen dem Ausmaß der Besserung und der Dauer der Erkrankung vor Behandlungsbeginn.

     

Efficacy of milnacipran on poststroke depression on inpatient rehabilitation

Post-stroke depression (PSD) has a negative impact on rehabilitation following stroke. No satisfactory antidepressant treatment for PSD has yet been developed. The present study examined the effect of milnacipran, a serotonin and norepinephrine reuptake inhibitor, on PSD patients. Eleven PSD patients taking milnacipran in a rehabilitation hospital were compared to age-matched, sex-matched, and severity of depression at admission-matched PSD patients hospitalized during 2001 who did not take any antidepressant as historical control. Severity of depression was measured using self-rating depression scale for depression (SDS) assessed at admission and discharge after 3 months inpatient rehabilitation. Activities of daily living (ADL) and quality of life (QOL) were measured, respectively, by the functional independence measure (FIM) and a self-completed questionnaire for QOL (QUIK) as outcomes of rehabilitation. For the SDS score, the group taking milnacipran showed significant improvement compared to the control group in our study. FIM was improved in both groups. In the end QUIK did not change significantly in either group. We found no major side-effects of milnacipran among the patients. These results suggest that milnacipran is a safe and effective treatment for PSD for inpatients undergoing rehabilitation.     

Influence of abciximab on the adhesion of platelets on a shielded plasma gradient prepared on polyethylene

INTRODUCTION: Thrombotic effects of biomaterial implants are mediated merely through activation of the platelet glycoprotein IIb-IIIa (GpIIb-IIIa) receptor. Consequently, platelet GpIIb-IIIa receptor inhibitors are successfully used during stent implantation procedures to prevent thrombosis. However, currently a new generation of stents contains surface coating, which changes the surface to more hydrophobic or hydrophilic. This change markedly affects the interaction of platelets and may influence the efficiency of GpIIb-IIIa inhibitors. MATERIALS AND METHODS: To study the influence of the wettability of biomaterials on the effectiveness of abciximab, 5-cm polyethylene gradients with contact angles of 100 degrees to 40 degrees were made by means of glow discharge. Fresh whole blood with or without abciximab was recirculated over this gradient. RESULTS: Inhibition of platelet adhesion by abciximab was maximal, but not complete, on the hydrophobic and moderate hydrophobic part of the gradient, with contact angles of 55 degrees to 90 degrees. Percentage inhibition by abciximab was maximal around 60 degrees. CONCLUSIONS: Intermediate hydrophobicity of currently applied stent materials, such as stainless steel, seems optimal in combination with abciximab. However, on hydrophobic and particularly on hydrophilic materials, abciximab is less effective.     

Clinical and experimental studies on the action of ethamsylate on haemostasis and on platelet functions

In a series of tests,the action of ethamsylate on haemostasis and on platelet functions was examined. After oral administration of the drug,a highly significant diminution of the bleeding time and of the blood loss from a standard wound was observed. This effect was demonstrated in healthy individuals and in patients suffering from platelet dysfunctions,and there was a distinct dose relation. There was also an increase of platelet adhesion,of PF 3 availability and of PF 4 release. The action of prostacyclin on the epinephrine induced platelet aggregation could be inhibited by ethamsylate. This offers a possible explanation for some of the effects on hemostasis. In addition,an action of ethamsylate on the platelet membrane was assumed since an in vitro increase of functions of the platelet membrane like PF 3 availability would not be explainable by a possible inhibition of prostacyclin.     

Laser therapy on points of acupuncture on nerve repair

正Paresthesia is the name given to a temporary or permanent sensory loss caused by several surgical procedures that affected the peripheral sensory nerve.In dentistry,common iatrogenic procedures that can lead to sensory loss include third molar removal,blocking of the inferior alveolar nerve     

散发神经鞘瘤22号染色体杂合子丢失发生的研究

目的探讨散发神经鞘瘤病人22号染色体（CHR22）杂合子丢失（LOH）情况及其与肿瘤增殖的关系。方法选取4个与NF2基因密切相关的多态性微卫星标记物,应用PCR方法研究54例神经鞘瘤的LOH情况。采用Ki-67和增殖细胞核抗原（PCNA）评估增殖指数。结果23例（42.6%）CHR22发生LOH,听神经鞘瘤发生率显著性高于脊神经鞘瘤（χ2=5.14,P〈0.05）。发生LOH者增殖指数明显高于无LOH者（Pki-67=0.0079,PPCNA=0.0021）。结论在散发神经鞘瘤中,CHR22LOH是常发事件;听神经瘤与脊神经鞘瘤LOH发生率有显著性差异,CHR22LOH与神经鞘瘤的增殖活动性有关。