Kaposi's sarcoma: case report and treatment options

Kaposi's sarcoma (KS) is strongly associated with Human Herpes Virus 8 (HHV8) and Human Immunodeficiency Virus infection (HIV). It was the first malignancy to be linked with Acquired Immunodeficiency Syndrome (AIDS). We report a case of Kaposi's sarcoma in a newly diagnosed retroviral homosexual patient with CD4 count of 21. He had multiple firm discrete violaceous plaques and nodules scattered over the face, scalp, hard palate, trunk and genitalia. Biopsy of a skin nodule over the trunk and a biopsy of a lesion from the gastric mucosa confirmed Kaposi's sarcoma. He was started on Highly Active Antiretroviral Therapy (HAART) and cryotherapy (liquid nitrogen) was given for the lesions over the skin. He responded well to treatment. Liquid nitrogen is a useful adjuvant treatment for Kaposi's sarcoma.     

卡波济肉瘤5例报告

卡波济肉瘤(Kaposi′s sarcoma.KS)又名多发性特发性出血性肉瘤(multipe idio-pathichemorrhagic sarcoma).1972年Kaposi′s首先报告了6例[1].该病较少见,但近年由于艾滋病迅速蔓延,其发病率明显上升,我国已陆续报告27例[2,3].尤其目前免疫功能异常疾病、器官移植、淋巴瘤、白血病及自身免疫性疾病等增多,以及激素及/或免疫抑制剂的应用都可能使该病增多.本文报告本院近20年确诊的5例经典型KS.     

Constrictive pericarditis and intestinal haemorrhage due to Whipple's disease

Two months after a pericardectomy for constrictive pericarditis a 37-year-old man presented with diarrhoea, abdominal pain and weight loss. During the course of investigation he developed brisk rectal bleeding and emergency angiography revealed a bleeding site related to an area of abnormal vasculature in the caecum. At laparotomy, the small bowel was found to be inflamed and the mesenteric lymph nodes enlarged. The overall histological appearances, confirmed later on endoscopic duodenal biopsies, were those of Whipple's disease. His symptoms resolved promptly after starting tetracycline therapy. The clinical features of Whipple's disease are protean and often bizarre. We report here a case where the diagnosis was made after the onset of profuse rectal bleeding.     

Digital clubbing in primary intestinal lymphangiectasia: a case report

Wiener Medizinische Wochenschrift - Primary intestinal lymphangiectasia (PIL), also known as Waldmann's disease, is a rare disorder characterized by dilated intestinal lacteals resulting in...     

小儿小肠炎症性肌纤维母细胞瘤1例

炎症性肌纤维母细胞瘤(inflammatory myofibroblastic tumor,IMT)是近年才正式命名的一类低度恶性肿瘤的总称,各部位均可发病,儿童少见,易形成过度治疗。我院于2012年1月收治了1例少见原发小肠IMT,现报告如下。     

A perplexing case of gastrointestinal haemorrhage

Choriocarcinoma is a gestational trophoblastic tumour with a high metastatic potential but presentation with gastrointestinal haemorrhage due to jejunal mucosal metastasis is very rare. A 25-year-old Nepali woman presented with severe anaemia and massive gastrointestinal haemorrhage after normal pregnancy following evacuation of a hydatiform mole. During laparotomy, the patient was found to have extensive jejunal mucosal metastases.     

Adult primary undifferentiated embryonal sarcoma of the liver: a case report

Undifferentiated embryonal sarcoma of the liver （UESL） was first described by Stocker and Ishak in 1978. It is a rare tumor that most often presents in childhood between 6 to 10 years of age.2 The adult patients diagnosed with UESL often show nonspecific symptoms with normal laboratory results. Ultrasonography, CT, or MRI often reveals a cystic mass. Complete surgical resection plus pre- and/or post-operative systemic chemotherapy offers the possibility of a cure. We report a case of primary UESL in an adult with no specific symptoms, tumor markers, or image results. The diagnosis of the case was based on the resulting pathology from surgery.     

胃肠道肿瘤复发致肠梗阻的外科治疗(附45例分析)

目的 探讨胃肠道恶性肿瘤术后腹腔肿瘤复发性肠梗阻的临床特点及诊治要点.方法 将81例胃肠道恶性肿瘤术后肠梗阻再手术患者分为肿瘤复发组45例和非复发组36例,对其病理、临床表现、治疗方法、术后并发症等方面进行回顾性分析对比.结果 两组在原发肿瘤分化程度、肿瘤分期、临床表现、梗阻类型、手术方式及术后并发并发症等方面存在显著性差异.结论 两组间的上述差异点可作为胃肠道恶性肿瘤术后肿瘤复发性肠梗阻诊断的要点.手术方法以解除梗阻为首要目的.     

严重钙质沉着症1例报告

1病例资料 患者女,40岁,因全身多处钙化灶15年、右髂部破溃1年,于2015年7月20日入我院.患者自诉1994年因发热,面部皮疹,双手冰凉,遇冷变白、变紫就诊,经中国医学科学院皮肤病医院诊断为“系统性红斑狼疮”,给予泼尼松最大剂量60 mg口服、1次/d治疗,之后症状好转,但仍有雷诺现象(Raynaud's syndrom),泼尼松逐渐减量至15 mg.1997年出现关节痛,累及腕关节、踝关节,红细胞沉降率50 mm/1 h,尿蛋白(+),外院考虑“系统性红斑狼疮复发”,予泼尼松加量至30 mg口服、1次/d治疗,并加用雷公藤2片、3次/d口服,后泼尼松逐渐减量至10 mg口服、1次/d维持,雷公藤口服7个月出现闭经后停用,症状控制尚可,无特殊不适主诉.2000年患者自觉双侧髂部出现结节、质硬,局部皮肤可见结节突出,无压痛、瘙痒,无破溃,后渐累及大腿外侧、双臀部、双上肢外侧等部位,以骨盆处较明显,未予特殊治疗.     

原发性胸壁骨肉瘤第三次复发后再手术治疗(附1例报告)

1.1一般资料患者,男,18岁。在外院行右侧胸壁原发性骨肉瘤切除术后2年（术后接受8个疗程化疗和1个疗程放射治疗）;本次入院前1年内2次出现局部复发,分别于1年前和6个月前在外院行复发肿瘤切除;2个月前在前手术部位再次出现软组织肿块。入院后,患者一般情况良好,右前外侧胸壁可见3条前次手术瘢痕,腋前线第4、5肋间水平可见胸壁软组织包块（图1A）,累及皮肤面积约3 cm×4 cm,有轻压痛。胸部X线及CT片可见：右前外侧胸壁软组织肿块,约5 cm×6 cm×4 cm;溶骨和成骨现象混合出现;第4、5、6前肋缺失（前次手术切除）;左下肺单发圆形结节,直径约2 cm（图1B）。腹部B超、核素骨扫描、心电图、肺功能检查未见异常。术前诊断为原发性胸壁骨肉瘤局部复发伴左下肺转移。     

Pulmonary vein sarcoma: a case report

Recently, we treated a patient with pulmonary vein sarcoma. The patient was a 41-year-old woman, had cough, short of breath and apsychia, with obvious jugular venous distention, rales in both lungs and a diastolic murmur at the apex. CT and Echo revealed a tumor in the left atrium. She received an emergency surgery to remove the mass in the heart. The pathological diagnosis demonstrated it as leiomyosarcoma. Though the patient accepted radiotherapy and chemotherapy, she still died of recurrence and metastasis of the sarcoma 10 months after operation.