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1.
Magnetization transfer effects in multislice RARE sequences. 总被引:1,自引:0,他引:1
Magnetization transfer effects are demonstrated to be significant in determining the signal intensity from brain tissues on images acquired with multislice rapid acquisition relaxation enhanced (RARE) sequences. We report studies designed to determine how the signal intensities vary with slice number or, equivalently, off-resonance power deposition. The results obtained in fat, gray matter, and white matter are similar in form to those reported in kidney tissues during classic magnetization transfer experiments (J. Eng, T. L. Ceckler, and R. S. Balaban, Magn. Reson. Med. 17, 304 (1991)). Of clinical significance to RARE practitioners is the increase of contrast-to-noise ratios between gray and white matter on proton density-weighted images with increasing slice number. 相似文献
2.
An implementation of fast spin echo at 4.7 T designed for versatile and time‐efficient T2‐weighted imaging of the human brain is presented. Reduced refocusing angles (α < 180°) were employed to overcome specific absorption rate (SAR) constraints and their effects on image quality assessed. Image intensity and tissue contrast variations from heterogeneous RF transmit fields and incidental magnetization transfer effects were investigated at reduced refocusing angles. We found that intraslice signal variations are minimized with refocusing angles near 180°, but apparent gray/white matter contrast is independent of refocusing angle. Incidental magnetization transfer effects from multislice acquisitions were shown to attenuate white matter intensity by 25% and gray matter intensity by 15% at 180°; less than 5% attenuation was seen in all tissues at flip angles below 60°. We present multislice images acquired without excess delay time for SAR mitigation using a variety of protocols. Subsecond half Fourier acquisition single‐shot turbo spin echo (HASTE) images were obtained with a novel variable refocusing angle echo train (20° < α < 58°) and high‐resolution scans with a voxel volume of 0.18 mm3 were acquired in 6.5 min with refocusing angles of 100°. Magn Reson Med, 2009. © 2009 Wiley‐Liss, Inc. 相似文献
3.
Novak V Kangarlu A Abduljalil A Novak P Slivka A Chakeres D Robitaille PM 《Journal of computer assisted tomography》2001,25(3):431-435
PURPOSE: Optimal treatment strategies and neurologic outcome after stroke depend on an accurate characterization of the lesion. There is a need for high resolution noninvasive imaging for assessment of the infarct size, perfusion, and vascular territory. MRI at the ultra high field (UHF) of 8 T offers unprecedented resolution, but its utility for stroke evaluation has not been determined yet. METHOD: A 55-year-old man with hypertension experienced sudden onset of speech arrest and right-sided hemiparesis that resolved in < 24 h with minimal neurologic deficit. MRI at 1.5 T showed initially a left posterior frontal lesion with subacute infarct (hyperintense on T2-weighted spin echo images) and right-sided frontal and periventricular lesions consistent with chronic infarct. There were many smaller white matter lesions. Delayed studies showed high signal changes involving the gray matter only on T1-weighted images. RESULTS: Gradient echo and rapid acquisition with relaxation enhancement (RARE) multislice images revealed a serpentine area of low signal in the left posterior frontal lobe gray matter suggestive of a hemorrhagic infarct, right-sided frontal lesion also showing iron deposits, multiple periventricular and cortical areas with abnormal high signal regions that were consistent with old infarcts, and numerous small vessels readily visible, more prominent on the right. CONCLUSION: MRI at 8 T displays lesions with a high resolution and striking anatomic details. Susceptibility to iron and sensitivity to detect blood products are increased at 8 T. The imaging characteristics at high field are different from those at low field, but both represent findings of iron products. 相似文献
4.
L A Loevner R I Grossman J C McGowan K N Ramer J A Cohen 《AJNR. American journal of neuroradiology》1995,16(7):1473
PURPOSETo investigate the relationship between the appearance of multiple sclerosis lesions identified on unenhanced T1-weighted images and their corresponding magnetization transfer ratios.METHODSA total of 119 white matter lesions seen on T2-weighted images in 17 patients with multiple sclerosis were evaluated. Axial T1-weighted images were used to classify the lesions as isointense to white matter (10 lesions), hypointense to white matter but hyperintense to gray matter (44 lesions), hypointense to gray matter (59 lesions), and relatively isointense to cerebrospinal fluid (6 lesions). The magnetization transfer ratio of each lesion was calculated, and an average magnetization transfer ratio for each subcategory was determined.RESULTSThe magnetization transfer ratio values became progressively lower with increasing hypointensity of lesions on T1-weighted images. The average magnetization transfer ratio for lesions isointense to white matter, hypointense to white matter but hyperintense to gray matter, hypointense to gray matter, and relatively isointense to cerebrospinal fluid was 34.90 +/- 2.67 mean +/- SD), 30.93 +/- 3.57, 27.27 +/- 3.56, and 23.62 +/- 2.83, respectively. All groups were significantly different from each other.CONCLUSIONLesions isointense to white matter exhibited higher magnetization transfer ratio values than lesions that were hypointense. These findings are consistent with relative preservation of the myelin structure in the former, perhaps indicating that these lesions are predominantly inflammatory (edematous) in nature. The proportionately lower magnetization transfer ratio values of lesions that appear progressively more hypointense on T1-weighted images may reflect varying degrees of demyelination, with increasing lesion hypointensity corresponding to more breakdown in the macromolecular structure. These results suggest that T1-weighted images may be useful in characterizing the underlying pathologic substrate in multiple sclerosis plaques. 相似文献
5.
Donald G. Mitchell Eric K. Outwater Simon Vinitski 《Journal of magnetic resonance imaging : JMRI》1994,4(2):109-117
Hybrid RARE (rapid acquisition with relaxation enhancement) is a family of magnetic resonance (MR) imaging techniques whereby a set of images is phase encoded with more than one spin echo per excitation pulse. This increases the efficiency of obtaining T2-weighted images, allowing greater flexibility regarding acquisition time, resolution, signal-to-noise ratio, and tissue contrast. Hybrid RARE techniques involve several important new user-selectable parameters such as effective TE, echo train length, and echo spacing. Choices of other parameters, such as TR, sampling bandwidth, and acquisition matrix, may be different from those of comparable conventional T2-weighted spin-echo images. Different hybrid RARE implementations can be used for abdominal screening, with T2-weighted or T2-weighted and inversion-recovery contrast, or for characterizing liver lesions or imaging the biliary system with an extremely long TE. High-resolution images may be obtained by averaging multiple signals during quiet breathing, or images may be acquired more rapidly during suspended respiration. In this review, the authors discuss the basic principles of hybrid RARE techniques and how various imaging parameters can be manipulated to increase the quality and flexibility of abdominal T2-weighted MR imaging. 相似文献
6.
Transverse relaxation (T2) mapping has many applications, including imaging of iron accumulation in grey matter. Using the typical multiecho spin‐echo sequence with long echo trains, stimulated echo compensation can enable T2 fitting under conditions of variable radio frequency homogeneity arising from slice profile and in‐plane radio frequency variation. Substantial reduction in the number of refocusing pulses could enable use at high magnetic fields where specific absorption rate is a major limitation, and enable multislice use with reduced incidental magnetization transfer at all field strengths. We examine the effect of reduced echo train lengths and multislice imaging on T2 fitting using stimulated echo compensation applied to iron‐rich subcortical grey matter in human brain at 4.7 T. Our findings indicate that reducing from 20 echoes to as few as four echoes can maintain consistent T2 values when using stimulated echo compensation in grey and white matter, but not for cerebrospinal fluid. All territories produce marginal results when using standard exponential fitting. Savings from reduced echoes can be used to substantially increase slice coverage. In multislice mode, the resulting incidental magnetization transfer decreased brain signal but had minimal effect on measured T2 values. Magn Reson Med 70:1340–1346, 2013. © 2013 Wiley Periodicals, Inc. 相似文献
7.
P S Melki R V Mulkern L P Panych F A Jolesz 《Journal of magnetic resonance imaging : JMRI》1991,1(3):319-326
The FAISE (fast-acquisition interleaved spin-echo) technique consists of a hybrid rapid-acquisition relaxation-enhanced (RARE) sequence combined with a specific phase-encode reordering method. Implemented on a 1.5-T unit, this multisection, high-resolution technique permits convenient contrast manipulation similar to that of spin-echo imaging, with selection of a pseudo-echo-time parameter and a TR interval. With a TR of 2 seconds, eight 256 x 256 images are obtained in 34 seconds with either T2 or proton-density weighting. A direct comparison between FAISE and spin echo for obtaining T2-weighted head images in healthy subjects indicates that FAISE and spin-echo images are qualitatively and quantitatively similar. Image artifacts are more pronounced on "proton-density" FAISE images than on the T2-weighted FAISE images. T1 contrast can be obtained with inversion recovery and short TR FAISE images. Preliminary temperature measurements in saline phantoms do not indicate excessive temperature increases with extended FAISE acquisitions. However, extensive studies of radio-frequency power deposition effects should be performed if the FAISE technique is to be fully exploited. 相似文献
8.
Rapid acquisition relaxation-enhanced (RARE) sequences (Hennig et al., Magn. Reson. Med. 3, 823 (1986)) utilize one or several Carr-Purcell-Meiboom-Gill (CPMG) echo trains to sample a number of k-space lines each repetition time TR. The technique can rapidly generate multislice T2-weighted images which, as a rule, are strikingly similar in contrast to conventional T2-weighted spin-echo (SE) images. An exception to this rule is the appearance of very bright signal from fat in T2-weighted RARE images as compared to conventional T2-weighted SE images. To reduce this fat signal, we introduce a time delay, tau c, between the 90 degrees x and first 180 degrees y pulse of each echo train such that a phase angle of pi/2 develops between fat and the reference (water) line at echo maxima. The technique leads to single-acquisition fat suppression without the use of frequency-selective saturation pulses and concomitant loss of slices per TR. A Bloch equation analysis is used to identify two major mechanisms contributing to suppression of off-resonance spins such that w tau c = pi/2. Namely, the CPMG sequence becomes a CP sequence with no self-correction properties for imperfect 180 degrees pulses leading to enhanced signal decay, and the raw k-space data matrix become segmented into blocks alternately multiplied by +/- i, leading to signal dispersion following Fourier transformation. 相似文献
9.
Optimized T1-weighted contrast for single-slab 3D turbo spin-echo imaging with long echo trains: application to whole-brain imaging. 总被引:1,自引:0,他引:1
Jaeseok Park John P Mugler Wilhelm Horger Berthold Kiefer 《Magnetic resonance in medicine》2007,58(5):982-992
T(1)-weighted contrast is conventionally obtained using multislice two-dimensional (2D) spin-echo (SE) imaging. Achieving isotropic, high spatial resolution is problematic with conventional methods due to a long acquisition time, imperfect slice profiles, or high-energy deposition. Single-slab 3D SE imaging was recently developed employing long echo trains with variable low flip angles to address these problems. However, long echo trains may yield suboptimal T(1)-weighted contrast, since T(2) weighting of the signals tends to develop along the echo train. Image blurring may also occur if high spatial frequency signals are acquired with low signal intensity. The purpose of this work was to develop an optimized T(1)-weighted version of single-slab 3D SE imaging with long echo trains. Refocusing flip angles were calculated based on a tissue-specific prescribed signal evolution. Spatially nonselective excitation was used, followed by half-Fourier acquisition in the in-plane phase encoding (PE) direction. Restore radio frequency (RF) pulses were applied at the end of the echo train to optimize T(1)-weighted contrast. Imaging parameters were optimized by using Bloch equation simulation, and imaging studies of healthy subjects were performed to investigate the feasibility of whole-brain imaging with isotropic, high spatial resolution. The proposed technique permitted highly-efficient T(1)-weighted 3D SE imaging of the brain. 相似文献
10.
In this work, both T1- and T2-weighted fast imaging methods at 8 T are presented. These include the modified driven equilibrium Fourier transform (MDEFT) and rapid acquisition with relaxation enhancement (RARE) methods, respectively. Axial MDEFT images were acquired with large nutation angles, both partially suppressing gray and white matter and permitting the visualization of vascular structures rich in unsaturated spins. Sagittal RARE images, acquired from the same volunteer, were highly T2-weighted, thus highlighting the CSF. At the same time, they provided good visualization of the corpus callosum, cerebellum, and gray and white matter structures. Importantly, both MDEFT and RARE images could be acquired without violating specific absorption rate guidelines. 相似文献
11.
The fast acquisition interleaved spin-echo (FAISE) sequence and its dual-echo version (DEFAISE) are partial RF echo-planar methods which utilize a specific phase-encode reordering algorithm to manipulate T2 contrast via an operator-controlled pseudo-echo time, pTE. The repetition time, TR, between successive applications of the Carr-Purcell-Meiboom-Gill (CPMG) echo trains used in FAISE may be reduced to introduce T1 weighting. To quantitatively determine the extent to which FAISE T1 and T2 contrast characteristics agree with spin-echo methods, signal intensities from FAISE acquisitions were compared with signal intensities from equivalent CPMG acquisitions. In phantoms and in human heads, the contrast characteristics of FAISE are found to be highly correlated with that obtained with equivalent CPMG sequences. However, conventional SE sequences generally utilize longer echo spacings than employed with FAISE/CPMG. Thus, echo spacing-dependent mechanisms such as spin-spin coupling and magnetic susceptibility lead to some differences in contrast between conventional SE and FAISE. Finally, FAISE appears to be more sensitive to magnetization transfer effects than conventional SE sequences since more off-resonance irradiation is applied to individual slices during multislice acquisitions. 相似文献
12.
The fast acquisition interleaved spin-echo (FAISE) method is a partial RF echo-planar technique which utilizes a specific phase-encode reordering algorithm to manipulate image contrast (Melki et al., J. Magn. Reson. Imaging 1:319, 1991). The technique can generate "spin-echo" like images up to 16 times faster than conventional spin-echo methods. However, the presence of T2 decay throughout the variable k-space trajectories used to manipulate T2 contrast ensures the presence of image artifacts, especially along the phase-encode direction. In this work, we experimentally and theoretically examine the type and extent of artifacts associated with the FAISE technique. We demonstrate the existence of well-defined minima of phase-encode ghost noise for selected k-space trajectories, examine the extent of blurring and edge enhancement artifacts, demonstrate the influence of matrix size and number of echoes per train on phase-encode artifact, and show how proper choice of FAISE sequence parameters can lead to proton density brain images which are practically indistinguishable from conventional spin-echo proton density images. A comparison of contrast between FAISE and standard spin-echo methods is presented in a companion article referred to as II. 相似文献
13.
RASER: a new ultrafast magnetic resonance imaging method. 总被引:1,自引:0,他引:1
Ryan Chamberlain Jang-Yeon Park Curt Corum Essa Yacoub Kamil Ugurbil Clifford R Jack Michael Garwood 《Magnetic resonance in medicine》2007,58(4):794-799
A new MRI method is described to acquire a T(2)-weighted image from a single slice in a single shot. The technique is based on rapid acquisition by sequential excitation and refocusing (RASER). RASER avoids relaxation-related blurring because the magnetization is sequentially refocused in a manner that effectively creates a series of spin echoes with a constant echo time. RASER uses the quadratic phase produced by a frequency-swept chirp pulse to time-encode one dimension of the image. In another implementation the pulse can be used to excite multiple slices with phase-encoding and frequency-encoding in the other two dimensions. The RASER imaging sequence is presented along with single-shot and multislice images, and is compared to conventional spin-echo and echo-planar imaging sequences. A theoretical and empirical analysis of the spatial resolution is presented, and factors in choosing the spatial resolution for different applications are discussed. RASER produces high-quality single-shot images that are expected to be advantageous for a wide range of applications. 相似文献
14.
Pedersen M Klarhöfer M Christensen S Ouallet JC Ostergaard L Dousset V Moonen C 《Journal of magnetic resonance imaging : JMRI》2004,20(6):930-940
PURPOSE: To evaluate the feasibility of using the rapid principles of echo shifting with a train of observations (PRESTO) sequence for measurements of cerebral hemodynamic parameters based on first pass of a contrast agent. MATERIALS AND METHODS: Simulations were performed to investigate potential resolution loss due to relaxation effects. Experimental evaluation was conducted in healthy monkey brains using PRESTO and echo-planar imaging (EPI). RESULTS: For short echo trains, an insignificant contribution of the longitudinal and transversal relaxation rates to the signal amplitude in white matter and gray matter was found, whereas a contribution as large as 40% was found in large vessels. Simulations of the point spread function demonstrated that PRESTO, despite its shorter readout trains, only has a small advantage in terms of maintenance of image resolution during bolus passage compared to EPI as long as the EPI echo train can be kept similar to the T2* value at the top of the bolus. Experimental studies revealed that the PRESTO and EPI gray matter to white matter ratio were similar with respect to cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT). CONCLUSION: The study showed that PRESTO and EPI led to comparable quantitative perfusion parameters. 相似文献
15.
A generalized k-sampling scheme for 3D fast spin echo 总被引:1,自引:0,他引:1
Kholmovski EG Parker DL Alexander AL 《Journal of magnetic resonance imaging : JMRI》2000,11(5):549-558
The phase-encoding scheme can significantly affect the quality of fast spin-echo (FSE) images because the echo amplitude is modulated as a function of the echo position in k-space. The effects of the modulation in two-dimensional FSE imaging include ghosting and blurring artifacts and resolution loss in the phase-encoding (PE) direction. In 3D FSE imaging, the use of two PE directions presents the opportunity for improved PE schemes. A new scheme for assignment of echoes to views in 3D FSE, termed generalized, has been developed. This scheme distributes T(2) effects along both PE directions, allowing considerable flexibility in the selection of blurring artifact appearance. In a set of simulations, phantom experiments, and in vivo experiments, the performance of the generalized PE scheme for 3D FSE imaging was compared with the performance of existing PE schemes. The results demonstrate that the generalized PE scheme can be used to reduce blurring artifacts greatly relative to other PE techniques that are presently in use. This approach to PE can be used to manipulate the blurring artifact appearance and to optimize acquisition time. 相似文献
16.
Neville D. Gai PhD John A. Butman MD PhD 《Journal of magnetic resonance imaging : JMRI》2009,30(3):640-648
Purpose
To demonstrate a modification of the Look‐Locker (LL) technique that enables rapid high resolution T1 mapping over the physiologic range of intracranial T1 values, ranging from white matter to cerebrospinal fluid (CSF). This is achieved by use of a three‐dimensional (3D) balanced steady‐state free precession (b‐SSFP) acquisition (for high signal‐to‐noise and resolution) along with variable repetition time to allow effective full recovery of longitudinal magnetization.Materials and Methods
Two modifications to the Look‐Locker technique were made to realize high resolution imaging in a clinically reasonable scan time. The 3D b‐SSFP acquisition after an initial inversion pulse was followed by a variable repetition time. This technique makes it possible to image a volume of thin contiguous slices with high resolution and accuracy using a simple fitting procedure and is particularly useful for imaging long T1 species such as CSF. The total scan time is directly proportional to the number of slices to be acquired. The scan time was reduced by almost half when the repetition time was modified using a predesigned smooth function. Phantoms and volunteers were imaged at different resolutions on a 3 Tesla scanner. Results were compared with other accepted techniques.Results
T1 values in the brain corresponded well with full repetition time imaging as well as inversion recovery spin echo imaging. T1 values for white matter, gray matter, and CSF were measured to be 755 ± 10 ms, 1202 ± 9 ms, and 4482 ± 71 ms, respectively. Scan times were reduced by approximately half over full repetition time measurements.Conclusion
High resolution T1 maps can be obtained rapidly and with a relatively simple postprocessing method. The technique is particularly well suited for long T1 species. For example, changes in the composition of proteins in CSF are linked to various pathologies. The T1 values showed excellent agreement with values obtained from inversion recovery spin‐echo imaging. J. Magn. Reson. Imaging 2009. © 2009 Wiley‐Liss, Inc. 相似文献17.
Motion artifact suppression technique (MAST) for MR imaging 总被引:3,自引:0,他引:3
P M Pattany J J Phillips L C Chiu J D Lipcamon J L Duerk J M McNally S N Mohapatra 《Journal of computer assisted tomography》1987,11(3):369-377
A technique has been developed that significantly improves the image resolution and reduces motion artifacts in conventional two-dimensional Fourier transform and three-dimensional Fourier transform magnetic resonance imaging sequences. Modifications on the gradient waveforms completely refocus the transverse magnetization at the echo time, regardless of the motion occurring between the time of the 90 degrees radiofrequency excitation and the echo time (within-view). This accomplishes suppression of motion artifacts and regains the signal from flowing blood and CSF. Images of the head, abdomen, chest, and spine are reproduced which show the increase in signal and anatomical detail that would otherwise be degraded and lost in artifact noise. This technique has reduced the practical difficulty of obtaining clinically diagnostic T2-weighted abdominal images. It also has allowed diagnostic quality T1- and T2-weighted images to be obtained with one acquisition per view, thus reducing the total scan time. 相似文献
18.
PURPOSETo determine whether magnetization transfer imaging can improve visibility of contrast enhancement of multiple sclerosis plaques.METHODSFifty-nine enhancing and 63 nonenhancing lesions in 10 patients with multiple sclerosis were evaluated to calculate contrast-to-noise ratios on conventional T1-weighted and T1-weighted magnetization transfer images. The signal intensity of the lesion and the background (white matter) were measured on precontrast T1-weighted and T1-weighted magnetization transfer images (800/20/1 [repetition time/echo time/excitations]) and on postcontrast T1-weighted and T1-weighted magnetization transfer images. Mean contrast-to-noise ratios was calculated for all lesions.RESULTSThe contrast-to-noise ratio was significantly higher for enhancing and nonenhancing lesions on T1-weighted magnetization transfer images than on conventional T1-weighted images. For enhancing lesions, the contrast-to-noise ratio was significantly higher on postcontrast T1-weighted magnetization transfer images, 32 +/- 2 compared with 21 +/- 2 on conventional T1-weighted images. Fifty of the 59 enhancing lesions were seen on both the T1-weighted and the T1-weighted magnetization transfer images. Nine enhancing lesions were seen only on the postcontrast T1-weighted magnetization transfer images. In addition, of 63 nonenhancing lesions seen on proton-density, T2-weighted, and T1-weighted magnetization transfer images, 16 were not seen on the conventional T1-weighted images. Seven of the 63 nonenhancing lesions and 7 of the 59 enhancing lesions had high signal intensity on the precontrast T1-weighted magnetization transfer images suggestive of lipid signal, a finding not seen on the conventional precontrast T1-weighted images.CONCLUSIONMagnetization transfer improves the visibility of enhancing multiple sclerosis lesions, because they have a higher contrast-to-noise ratio than conventional postcontrast T1-weighted images. High signal intensity on both nonenhancing and enhancing lesions noted only on precontrast T1-weighted magnetization transfer suggests a lipid signal was unmasked. If magnetization transfer is used in multiple sclerosis patients, a precontrast magnetization transfer image is necessary. 相似文献
19.
Hans-Peter Fautz Dominik Paul Klaus Scheffler Jürgen Hennig 《Magnetic resonance in medicine》2004,51(6):1239-1246
This article introduces a novel concept to overcome the dependence of image contrast on spatial positioning parameters such as the number of slices and slice separation in multislice measurements: TR-independent multislice (TRIM) acquisition allows the number of slices in a single measurement to remain independent of the repetition time TR. Ramped TRIM (rTRIM) allows the distance between the sections excited in each repetition to remain independent of the distance between the reconstructed slices. Even images from overlapping slices can be acquired without crosstalk between the images of adjacent slices due to spatially overlapping excitation profiles. This concept is based on a special reordering scheme: Within a single TR acquisition, steps are only taken from a fraction of all slices. This necessitates attribution of different phase-encoding steps to different slices within each repetition cycle. The reordering scheme can be derived by the use of a design matrix. The imaging properties of the technique are discussed theoretically and illustrated by a point spread function analysis based on simulations and phantom measurements. Potential sources of artifacts are identified and methods for their prevention are developed. Optimized implementations with different T(1)-weighted sequences such as spin echo (SE), turbo spin echo (TSE), and spoiled gradient echo acquisitions are shown on normal volunteers with imaging parameters used in routine diagnosis. 相似文献
20.
Douglas C. Noll 《Magnetic resonance in medicine》1994,31(3):323-327
The RARE method and its variants have become popular, rapid-imaging alternatives to conventional spin-echo imaging, particularly for long repetition time proton density and T2-weighted imaging. One variant is to generate both early and late echo images using the same pulse sequence, which has the added benefit of reduced edge artifacts and blurring. Described in this paper is variable-averaging RARE (VARARE), a method by which independent amounts of averaging can be set for the early and late echo images generated by a single scanning sequence. Through the use of this method, the signal-to-noise ratio (SNR) of late echo images can be improved without unnecessarily increasing the number of averages for the early echo image, thus saving scanning time. Comparisons to various alternatives are made with respect to scanning time and image quality. Phantom measurements and in vivo images are given to demonstrate the effectiveness of VA-RARE as an efficient method for improving SNR of late echo time images in RARE imaging. 相似文献