Changes in intraocular lens position after neodymium: YAG capsulotomy.

PURPOSE: To quantify changes in intraocular lens (IOL) position caused by neodymium: YAG (Nd:YAG) capsulotomy with 3 IOL styles. SETTING: Department of Ophthalmology, University of Vienna, Austria. METHODS: In a prospective study, anterior chamber depth (ACD) was measured by dualbeam partial coherence interferometry (PCI) in 32 pseudophakic eyes of 32 patients with posterior capsule opacification before and immediately after planned capsulotomy under mydriasis. Patients were divided into 3 groups with the following IOL styles: 1-piece poly(methyl methacrylate) (PMMA), 3-piece foldable, and plate haptic. RESULTS: The capsulotomy induced a backward IOL movement in all 32 eyes (mean 25 microns; range 9 to 55 microns). It was more pronounced in eyes with plate-haptic IOLs than in those with the other styles. Precision of ACD measurement by PCI was 4 microns. Changes in ACD correlated significantly with capsulotomy size but not with preoperative lens-capsule distance. CONCLUSION: Capsulotomy caused a backward movement of the IOL, which was more pronounced with plate-haptic IOLs than with 1-piece PMMA and 3-piece foldable IOLs. Since the magnitude of IOL movement in this study population was small, a hyperopic shift in refraction after capsulotomy will usually be small and not clinically relevant.     

Change in IOL position and capsular bag size with an angulated intraocular lens early after cataract surgery

PURPOSE: To investigate the axial movement in the first postoperative week and the influence of capsular bag size with an angulated, 3-piece, open-loop, acrylic intraocular lens (IOL). SETTING: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. METHODS: Twenty-nine eyes of 29 patients with age-related cataract were included in this study. In study 1, an open-loop, 3-piece IOL (AR40e, AMO) was implanted in a standardized fashion in 15 eyes of 15 patients. In study 2, before IOL implantation, a capsular tension ring (CTR) was inserted (14 eyes of 14 patients). Anterior chamber depth (ACD) was assessed with partial coherence interferometry 2 hours; 1, 3, and 5 days; 1 week; and 1 month postoperatively. The capsular bag diameter (CBD) was assessed using gonioscopic measurement of the eyelets of the CTR 1 day, 1 week, and 1 month postoperatively. RESULTS: In the first postoperative week, there was a significant mean forward movement of -196 microm +/- 117 (SD) (P < .005) in study 1 and -139 +/- 97 microm in study 2 (P < .005). These movements correspond to refractive changes of -0.31 diopter (D) and -0.20 D, respectively. The movement was linear in the first 5 days after surgery. Different patterns of early postoperative movement were seen, illustrating interindividual variability. A significant correlation of 0.67 (P < .05) was found between the change in ACD and CBD. CONCLUSIONS: A linear forward movement of the IOL during the first postoperative week was followed by a relatively stable IOL position. Loss of haptic memory seemed to be the most likely cause. Myopic eyes with large capsular bags showed less IOL shift in the early postoperative period than hyperopic eyes with smaller capsular bags.     

Effect of optic edge design and haptic angulation on postoperative intraocular lens position change

PURPOSE: To assess the effect of optic edge design and optic-haptic angulation of open-loop intraocular lenses (IOLs) on postoperative axial movement and the final position of the optic by measuring the anterior chamber depth (ACD) during the first postoperative year using partial coherence interferometry (PCI). SETTING: Department of Ophthalmology, Vienna General Hospital, Institute of Medical Physics, University of Vienna, Vienna, Austria. METHODS: In study 1, a 3-piece silicone IOL with nonangulated modified C-loop haptics (MicroSil, Dr. Schmidt) was implanted in 78 eyes of 39 patients; patients were randomized to receive a round-edged optic IOL in 1 eye and a sharp-edged optic IOL in the other eye. The ACD was measured by PCI 1 day, 1 week, 3 months, and 1 year after surgery. In study 2, a foldable, 3-piece acrylic IOL with modified 10-degree angulated J-loop haptics (AcrySof MA60BM, Alcon) was implanted in 32 eyes of 32 patients. The ACD was measured by PCI 1 day, 1 week, and 3 months after surgery. RESULTS: In eyes with a nonangulated silicone IOL, there was a significant postoperative change in ACD with both sharp-edged and round-edged designs (P<.01). There was forward movement of both IOL designs in the first week, with no significant difference between the 2 models. From 1 week to 3 months, there was backward movement of IOLs of both designs, with the sharp-edged IOL moving a significantly greater amount (P<.001). From 3 months to 1 year, IOLs with both optic edge designs moved slightly backward. Sixty-six percent of angulated IOLs showed continuous but variable forward movement and 34%, backward movement. CONCLUSIONS: Optic edge design influenced postoperative axial optic movement and thus had an impact on the development of postoperative refraction (refractive shift, deviation from target refraction). The influence of optic-haptic angulation proved to be significantly greater and more variable than edge design.     

Postoperative change in effective lens position of a 3-piece acrylic intraocular lens

PURPOSE: To study the change in postoperative position of an angulated, 3-piece, foldable acrylic intraocular lenses (IOLs) and evaluate the effect of a sharp posterior optic edge compared with that of a round optic edge on the change in postoperative anterior chamber depth (ACD). SETTING: Department of Ophthalmology, University of Vienna, Vienna, Austria. METHODS: This randomized intraindividual-comparison study comprised 104 eyes of 52 patients with age-related cataract. Patient received a sharp-edged Sensar OptiEdge AR40e IOL (Allergan Surgical) in 1 eye and a round-edged Sensar AR40 IOL in the other eye. Postoperative follow-up included ACD measurement by partial coherence interferometry and evaluation of the capsulorhexis area by standardized retroillumination photography at 1 day, 1 week, and 1 and 6 months. RESULTS: A decrease in ACD during the first postoperative week was followed by a small increase in ACD during the first 6 months. There was no significant difference between the sharp-edged group and the round-edged group. CONCLUSIONS: The angulated 3-piece acrylic IOLs showed significant forward movement over the first postoperative 6 months. Although the change in refraction was small, there was variability among patients. The sharp posterior optic edge design did not affect the IOL's movement in the capsular bag.     

Laserinterferometric assessment of pilocarpine-induced movement of an accommodating intraocular lens: a randomized trial

PURPOSE: To measure the axial movement of an accommodating intraocular lens (IOL) induced by ciliary muscle contraction after application of pilocarpine. DESIGN: Randomized, controlled, patient- and examiner-masked trial with intrapatient comparison. PARTICIPANTS AND CONTROLS: One hundred ten eyes of 55 patients with age-related bilateral cataract. METHODS: This study was divided into 3 parts. In the first, the accommodating IOL (1CU) was compared with a 3-piece open-loop acrylic IOL that served as the control. In the second, to assess the effect of capsule fibrosis on the potential accommodating performance of the accommodating IOL, extensive polishing of the anterior capsule with a slit cannula was compared with standard surgery. In the third, the effect of a posterior capsulorhexis was compared with that of standard surgery. Anterior chamber depth (ACD) was assessed with partial coherence interferometry, measured before and after topical application of pilocarpine 2%, and near visual acuity (VA) was evaluated 3 months after surgery. MAIN OUTCOME MEASURE: Pilocarpine-induced change in ACD. RESULTS: The accommodating IOL showed a forward movement under pilocarpine with a median amplitude of movement of -314 microm (95% confidence interval [CI]: -148 to -592), compared with the backward movement of 63 microm (95% CI: 161 to -41) for the open-loop control IOL (P = 0.001). Capsule polishing and a posterior capsulorhexis had no effect on IOL movement with the accommodating IOL. The median near VA with distance correction was 20/60. CONCLUSION: Pilocarpine induced a small but significant forward movement of the accommodating IOL. However, the amount of movement was calculated to result in a refractive change of <0.5 diopters (D) in most patients, reaching 1 D or slightly more in only single cases, with a large variability of movement. Neither polishing of the capsule bag nor a posterior capsulorhexis could enhance the accommodative ability.     

Scheimpflug measurement of intraocular lens position after piggyback implantation of foldable intraocular lenses in eyes with high hyperopia

PURPOSE: To investigate the position of 3-piece foldable intraocular lenses (IOLs) after piggyback implantation for high hyperopia. SETTING: University Eye Hospital, Johann Wolfgang Goethe University, Frankfurt am Main, Germany. METHODS: Eight eyes of 5 highly hyperopic patients had phacoemulsification and implantation of 2 foldable IOLs. In 3 eyes, both IOLs were implanted in the capsular bag. In 5 eyes, 1 IOL was placed in the capsular bag and the second IOL in the ciliary sulcus. Intraocular lens optic tilt and decentration, combined thickness of both IOLs, and anterior chamber depth (ACD) were measured postoperatively over a period of 18 months using Scheimpflug photography. RESULTS: All eyes with both IOLs in the capsular bag showed interpseudophakic opacification, with a mean increase in combined IOL thickness of 0.4 mm, a decrease in ACD of 0.3 mm, and a corresponding hyperopic shift of 4.00 diopters. Eyes in which the anterior IOL was placed in the ciliary sulcus showed no changes in refraction or combined IOL thickness. In these eyes, the anterior IOL had a higher mean decentration (0.49 mm +/- 0.20 [SD] after 12 months) than the posterior IOL (0.21 +/- 0.13 mm after 12 months). CONCLUSIONS: Piggyback IOL implantation with placement of 2 foldable IOLs in the capsular bag can be followed by a hyperopic shift that may be caused in part by displacement of the IOLs. Placement of the anterior IOL in the ciliary sulcus can lead to higher decentration of this IOL.     

Pseudophakic accommodation with 2 models of foldable intraocular lenses

PURPOSE: To evaluate the amplitude of pseudophakic accommodation of 2 foldable intraocular lenses (IOLs) by measuring the anterior chamber depth (ACD) shift during a 1-year follow-up. SETTING: Department of Ophthalmology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary. METHODS: This prospective study comprised 44 eyes of 44 cataract patients operated on with phacoemulsification and in-the-bag implantation of Akreos Disc (22 eyes) or AcrySof MA60BM (22 eyes) IOLs. The ACD was measured by A-scan during fixation at 30 cm and again after instillation of cyclopentolate 1%. The ACD shift was calculated by subtracting the ACD under cyclopentolate from the ACD during fixation at 30 cm. Follow-up measurements were performed 3, 6, and 12 months after surgery. Statistical analysis concerning the difference between the 2 groups was done by the Student unpaired t test. RESULTS: The ACD shift was greater in the AcrySof group than in the Akreos Disc group at all 3 follow-up examinations. The difference was highly significant between the 2 groups at 6 and 12 months (both P = .004). After the operation, the ACD shift increased continuously with time in both groups. The mean ACD shift reached 0.57 mm +/- 0.25 (SD) in the AcrySof group and 0.42 +/- 0.24 mm in the Akreos group at 12 months. CONCLUSIONS: The 3-piece AcrySof MA60BM IOL with 10-degree posterior angulation had a significantly higher capacity for pseudophakic accommodation than the 1-piece plate-haptic Akreos Disc IOL. The continuous increase in the ACD shift in the postoperative period may mean that patients learn to achieve better accommodation with an IOL as time goes on.     

Optical coherence tomography assessment of capsule closure after cataract surgery

PURPOSE: To develop a technique for documenting and quantifying capsule bend formation in pseudophakic eyes, evaluate when the anterior and posterior lens capsules become completely apposed to the optic, and determine how soon a capsule bend is created at the optic edge of an intraocular lens (IOL) after cataract surgery. SETTING: Medical University of Vienna, Department of Ophthalmology, Vienna, Austria. METHODS: This prospective study comprised 33 eyes of 33 patients with age-related cataract who were scheduled to have cataract surgery. All eyes had phacoemulsification with implantation of 1 of 3 types of open-loop IOLs: 1-piece acrylic (SA60AT, Alcon), 3-piece acrylic (AcrySof MA60BM, Alcon), or 3-piece silicone (911A, AMO). Each group included 11 eyes. One and 3 days and 1, 2, 3, and 4 weeks after surgery, contact between the lens capsule and IOL optic as well as capsule bend formation were evaluated using optical coherence tomography (OCT). The postoperative times at which the capsule came into contact with the IOL optic and when the capsule bend formed were determined. RESULTS: One day postoperatively, the mean distance between the anterior capsule and the IOL was 197 microm in the 1-piece acrylic IOL group, 161 microm in the 3-piece acrylic IOL group, and 220 microm in the 3-piece silicone IOL group. The posterior capsule was in contact with the IOL on the same day or earlier than the anterior capsule in 28 patients (85%). Postoperatively, the capsule bend formed at a mean of 10 days in the 1-piece acrylic group, 13 days in the 3-piece acrylic group, and 15 days in the 3-piece silicone group. The short-term reproducibility of the OCT technique was excellent (r = 0.99). CONCLUSIONS: Optical coherence tomography produced cross-sectional tomograms of capsule-IOL contact in the early postoperative period. There was no significant difference in the time to capsule bend formation between the 3 IOLs. However, capsule bend formation at the optic edge occurred earlier with the 1-piece acrylic IOL than with the 3-piece silicone IOL.     

Sutureless intrascleral posterior chamber intraocular lens fixation

We report a technique for sutureless fixation of standard 3-piece posterior chamber intraocular lenses (PC IOLs) in the ciliary sulcus in eyes without capsule support, which we have used in cases of subluxated and luxated cataract and for secondary IOL implantation. Fixation of the haptics in a limbus-parallel scleral tunnel allows exact centration and provides axial stability of the PC IOL to prevent distortion. The technique uses uncomplicated maneuvers for standard 3-piece PC IOL fixation without the need for special haptic architecture or preparation.     

Comparison of the stability of 1-piece and 3-piece acrylic intraocular lenses in the lens capsule

PURPOSE: To compare the degrees of intraocular lens (IOL) decentration, tilt, and longitudinal movement; the refractive change; and anterior capsule contraction after cataract surgery between eyes with a 1-piece acrylic IOL with soft acrylic loops and eyes with a 3-piece acrylic IOL with rigid poly(methyl methacrylate) loops. SETTING: Hayashi Eye Hospital, Fukuoka, Japan. METHODS: Fifty-six patients had implantation of a 1-piece acrylic IOL in 1 eye and a 3-piece acrylic IOL in the fellow eye. The degree of IOL decentration and tilt, the anterior chamber depth (ACD), and the area of anterior capsule opening were measured using Scheimpflug videophotography 3 days and 1, 3, and 6 months postoperatively. The postoperative refractive status was also examined. RESULTS: The mean degrees of decentration and tilt in the 1-piece IOL group were similar to those in the 3-piece IOL group throughout the follow-up. The ACD did not change after surgery in the 1-piece group but showed significant shallowing in the 3-piece group (P < .0001). The spherical equivalent (SE) did not change in the 1-piece group, while the SE had a significant myopic shift of approximately 0.4 diopter in the 3-piece group. The percentage of anterior capsule contraction was similar between the groups. CONCLUSIONS: The degree of IOL decentration and tilt and percentage of anterior capsule contraction in eyes with a 1-piece acrylic IOL with soft acrylic loops were similar to those in eyes with a 3-piece acrylic IOL. The longitudinal movement of the 1-piece IOL was less than the movement of the 3-piece IOL, resulting in less postoperative myopic shift.     

Comparison of pilocarpine-induced and stimulus-driven accommodation in phakic eyes

With the recent introduction of potentially accommodative intraocular lenses (IOL), there is a need for methods to evaluate their accommodative potential. In most studies assessing IOL movement, pilocarpine is used to stimulate contraction of the ciliary muscle. The aim of this study is to determine if pilocarpine-induced ciliary muscle contraction is comparable to physiological stimulus-driven accommodation in young and presbyopic subjects. Ten emmetropic young subjects (23-25 years) and 11 emmetropic presbyopic subjects (51-62 years) were included in this study. Anterior chamber depth (ACD) and lens thickness (LT) were assessed with partial coherence interferometry (PCI). A moveable stimulus was coupled to the PCI equipment for measurement of biometric lens changes. ACD was measured with the stimulus at infinity and then at the subjects individual nearpoint, and after application of two drops of 2% pilocarpine. In young subjects, there was no significant difference in lens change between nearpoint and pilocarpine stimulation. Presbyopic subjects showed no relevant lens change when accommodating at the nearpoint, however, under pharmacologically induced ciliary muscle contraction with pilocarpine, there was a significant forward shift of the anterior and posterior lens pole, leading to a translational forward lens shift of about 150 microm. This study demonstrates that pilocarpine acts "physiologically" in young phakic subjects, but is a "superstimulus" in presbyopic phakic subjects. Therefore, IOL movement may be overestimated when using pilocarpine to stimulate accommodation.     

四种非球面人工晶状体植入术后倾斜和偏心的比较

目的 比较目前临床上常用的4种不同非球面人工晶状体(IOL)在囊袋内植入后偏心和倾斜的差异.方法 回顾性系列病例研究.回顾性分析单纯性白内障患者130只眼术行超声乳化白内障吸除联合IOL植入术后3个月的随访资料.患者分别植入一体四襻式亲水丙烯酸酯IOL(Akreos AO,美国Bausch & Lomb公司)、三体c形襻疏水丙烯酸酯IOL(Tecnis9003,美国AMO公司)、一体L形襻疏水丙烯酸酯IOL(SN60WF,Alcon)、一体C形襻亲水丙烯酸酯IOL(920H,Rayner)4种非球面IOL以及三体C形襻疏水丙烯酸酯球面IOL(AR40e,AMO).使用Pentacam三维眼前房测量系统采集各眼Scheimpflug图像,用Image-pro plus 6.0图像分析得出IOL的倾斜度和偏心量,满足正态分布和方差齐性的行单因素方差分析,采用SNK-q检验进行组间两两比较.结果 除AR40e组的IOL倾斜度之外,其余各组患者IOL偏心值和倾斜度在水平和垂直方向上的数值差异均无统计学意义,取倾斜或偏心的最大值作为该患者的最终结果.AO、Z9003、IQ、920H、AR40e各组患者IOL的平均倾斜度分别为2.08°、2.58°、1.72°、1.81°、3.22°,其差异有统计学意义(F=4.511,P=0.003);各组患者IOL的偏心量分别为0.04 mm、0.24 mm、0.25 mm、0.19 mm、0.18 mm,在垂直方向上其差异有统计学意义(F=4.162,P=0.047),而在水平方向上各组患者IOL偏心值差异则无统计学意义(F=3.921,P=0.056).Z9003组IOL的偏心量和倾斜度线性相关(r=-0.517,P=0.034).结论 不同非球面IOL囊袋内植入后无论倾斜和偏心,结果推断可能一体优于三体IOL,多襻支撑优于双襻支撑IOL,但仍需结合临床专业知识判断.     

Comparison of the biomechanical behavior of foldable intraocular lenses

PURPOSE: To compare a standardized battery of biomechanical laboratory tests to assess the performance of popular foldable intraocular lenses (IOLs). SETTING: Biomedical testing facilities, Alcon Research, Ltd., Fort Worth, Texas, USA. METHODS: Using industry-standard biomechanical testing techniques, 1- and 3-piece foldable IOLs (Alcon AcrySof MA60BM, MA30BA, SA30AL, SA60AT; Allergan Sensar AR40, PhacoFlex II SI-40NB; Bausch & Lomb Soflex LI61U; Pharmacia & Upjohn CeeOn 920) and a 1-piece all-poly(methyl methacrylate) (PMMA) IOL (Alcon MZ30BD) were tested under identical conditions with regard to (1) tensile/elastic properties by comparing haptic pull strength and haptic elongation and (2) compression properties by comparing haptic compression forces, haptic compression force decay over time, and axial displacement. All tests were performed with the IOLs submersed in a controlled-temperature water bath (mean 35 degrees C +/- 2 degrees C [SD]). RESULTS: For all IOLs, the ultimate elongation and pull strength of the haptics before failure was highest with the Alcon SA30AL and SA60AT. Similarly, the force required to compress haptics to a prescribed 10.0 mm diameter was least with the SA30AL and the SA60AT lenses. These 1-piece lenses also showed the least decay of residual compression force as a function of time. Optic displacement along the optical axis with haptic compression to 10.0 mm was least with the Alcon 1-piece IOLs and the all-PMMA control IOL. CONCLUSION: AcrySof 1-piece SA30AL and SA60AT IOLs demonstrated superior biomechanical characteristics over other foldable IOL designs.     

Complications of foldable intraocular lenses requiring explanation or secondary intervention--1998 survey

A survey of the complications associated with foldable intraocular lenses (IOLs) that required explantation or secondary intervention was sent to domestic members of the American Society of Cataract and Refractive Surgery in 1998. Preoperative data as well as patient signs and symptoms were obtained and postoperative results and outcomes assessed. The types of foldable IOLs explanted were tabulated. The percentage of each type removed and the common reasons for removal were as follows: 38%--3-piece monofocal silicone IOLs for incorrect lens power followed by dislocation/decentration; 31%--3-piece multifocal silicone IOLs for glare/optical aberrations; 16%--3-piece acrylic IOLs for glare/optical aberrations followed by incorrect lens power and dislocation; 15%--1-piece or plate-haptic silicone IOLs for dislocation/decentration followed by incorrect lens power. Visual outcomes were uniformly good in the 4 groups. Meticulous surgical technique, IOL insertion, and IOL power measurements, along with proper patient selection, are important factors in avoiding complications with foldable IOLs.     

Influence of surgery-related factors on the Nd:YAG laser capsulotomy rates of 3-piece silicone IOLs - analysis of 457 pseudophakic human globes obtained post mortem

BACKGROUND: The purpose of this study was to analyze any possible surgical reasons which may have had caused posterior capsule opacification in 3-piece silicone IOLs that had required Nd:YAG laser treatment. Special attention was given to 1) quality of cortical clean up, 2) type of haptic fixation, and 3) continuous curvilinear capsulorhexis (CCC) size and shape. MATERIALS AND METHODS: Human eyes obtained post-mortem implanted with 3-piece silicone optic - PMMA haptic (SI 40 NB) and 3-piece silicone optic - Prolene haptic (SI 30 NB) designs IOLs, accessioned between January 1993 and December 2000 were evaluated by gross examination from behind under an operating microscope using the Miyake-Apple posterior photographic technique. The area and intensity of Soemmerring's ring and type of fixation was studied in 457 eyes. The mean diameter of the CCC and relation of the CCC edge to the optic rim were analyzed in 221 eyes. RESULTS: 1) The amount of Soemmerring's ring formation was significantly larger in the group of IOLs requiring Nd:YAG capsulotomy in both the SI 40 NB and SI 30 NB design than in the IOLs without capsulotomies. 2) The percentage of not in-the-bag fixated IOLs in both the SI 40 NB and SI 30 NB design was larger in the "Nd:YAG groups", without being statistically significant. 3) The "Nd:YAG groups" showed a significant higher amount of non overlapping clock hours of the CCC edge in relation to the optic rim. CONCLUSION: 1) The data confirm the clinical assumption that the incidence of PCO is correlated with the cortical clean up. 2) Our findings also support the clinical assumption, that poor IOL fixation increases the risk of PCO. 3) This study also verifies the relation of the CCC to PCO, namely a relatively small CCC covering the entire optic rim is best to reduce the Nd:YAG laser rate.     

In vitro comparison of glistening formation among hydrophobic acrylic intraocular lenses(1)

PURPOSE: To compare glistening formation induced by temperature stressing in vitro among hydrophobic acrylic intraocular lenses (IOLs) available in the United States. SETTING: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. METHODS: Wagon Wheel (WW) packaged 1-piece AcrySof IOLs (Alcon), WW-packaged 3-piece AcrySof IOLs, and Sensar IOLs (Allergan Medical Optics) were analyzed in vitro for 5 consecutive days. Ten IOLs of each type were inserted into viewing chambers filled with balanced salt solution, maintained at 37 degrees C, and evaluated every 24 hours at 37 degrees C and then, after a 2-hour cooling, at room temperature. The IOLs were examined by slitlamp to quantify glistenings and by digital photography to determine glistening size. RESULTS: The glistening quantity was minimal and did not differ among IOL types at 37 degrees C. The glistenings were smallest in the 1-piece AcrySof IOLs (P <.001): 6.3 microm versus 11.5 microm in the Sensar and 13.4 microm in the 3-piece AcrySof. Upon cooling, the glistening quantity increased dramatically in the 1-piece AcrySof IOLs (P <.008) and was the highest among the IOL types at room temperature (P <.001). The mean glistening size was 7.7 microm. The 3-piece AcrySof IOLs showed a significant decrease in slitlamp-countable glistenings but acquired a dense haze seen as minute glistenings (4.0 microm) at x80 magnification. The glistening quantity in the Sensar IOLs was fairly stable upon cooling; a statistical increase was seen on the last day (P =.007). Cooling nearly doubled the size of the Sensar glistenings, which were the largest at room temperature, 21.7 microm (P <.001). CONCLUSIONS: Glistening quantity varied among hydrophobic acrylic IOLs and was temperature dependent. Sensar IOLs were more stable than the 2 other IOL types. The glistening phenomenon must be studied further to eliminate the problem.     

Efficacy of haptic sutured in-the-bag intraocular lens for intraocular lens-capsule complex stability: a comparison of three insertion methods

AIM: To evaluate the efficacy and stability of haptic sutured in-the-bag intraocular lens (IOL) in eyes with zonular instability. METHODS: A total 60 eyes of 60 patients were included in this retrospective cohort study. Postoperative stability in three groups [haptic sutured IOL in the bag, IOL in the bag insertion with haptics oriented toward areas of zonulysis, IOL with capsular tension ring (CTR) in the bag insertion] were compared according to the IOL insertion methods. To evaluate the IOL stability, the changes of anterior chamber depth (ACD), refraction, contraction of anterior continuous curvilinear capsulotomy (CCC) area, and tilt of IOL were compared. RESULTS: There was no significant difference in change of ACD (-0.04±0.01 mm in group of haptic sutured IOL, -0.07±0.01 mm in group of CTR insertion) and refraction (0.05±0.05 D in group of haptic sutured IOL, 0.37±015 D in group of CTR insertion) between the group of haptic sutured IOL in the bag and CTR insertion group. But in comparison of CCC contraction and IOL tilt, CTR insertion group showed less contraction (1.00%±0.52%) and less IOL tilt (2.66°±0.11°) than the group of haptic sutured IOL in the bag (6.32%±1.36%, 3.47°±0.11°, respectively). The CTR insertion group showed the least CCC contraction and the least tilt. CONCLUSION: In eyes with zonular instability, the method of haptic sutured IOL in-the-bag shows comparable stability in ACD and refraction in comparison with IOL with CTR in the bag insertion. The method of IOL only in-the-bag insertion shows the largest contraction of CCC and the largest tilt of IOL.     

Rates and causes of intraoperative removal of foldable and rigid intraocular lenses: clinicopathological analysis of 100 cases

PURPOSE: To analyze the rates of and reasons for intraoperative explantation of foldable and rigid intraocular lenses (IOLs) to determine the complication profile of each IOL design. SETTING: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. METHODS: The study comprised data analysis of foldable (n = 85) and rigid (n = 15) IOL specimens that were explanted immediately after primary implantation. RESULTS: Eighty-five foldable intraoperative explants were accessioned. These comprised 14.5% of the 586 foldable IOL explants received between January 1988 and September 2000. There were 15 rigid poly(methyl methacrylate) (PMMA) intraoperative explants out of 2077 rigid explant specimens (0.7%). Fifty-one (60%) of the foldable IOLs requiring intraoperative explantation were the 1-piece silicone plate-haptic large-hole design, and 29 (34.1%) were the 3-piece silicone polyimide-haptic design. The most frequent reason for explantation of both designs was optic damage, 37.3% in the large-hole design and 55.2% in the polyimide design. Optic damage did not occur in rigid PMMA IOLs. CONCLUSION: Some foldable IOL designs have a higher risk of damage during surgical insertion than rigid designs. Two modern foldable IOLs, the silicone plate-haptic large-hole and the silicone polyimide-haptic, appear to be more prone to damage during folding, loading, and implantation than other IOLs.     

Effect of four different intraocular lenses on posterior capsule opacification

AIM: To evaluate the impact of 4 different intraocular lenses (IOLs) on posterior capsule opacification (PCO) by comparing the neodymium: yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy rates. METHODS: This retrospective study included 4970 eyes of 4013 cataract patients who underwent phacoemulsification and IOL implantation between January 2000 and January 2008 by the same surgeon at one clinic. Four different IOLs were assessed. The outcome parameter was the incidence of Nd:YAG laser posterior capsulotomies. RESULTS: An Nd:YAG laser posterior capsulotomy was performed in 153 (3.07%) of the 4970 eyes. The mean follow-up time was 84mo for all of the IOL groups. The percentage of eyes developing PCO was significantly greater for the acrylic hydrophilic IOLs than for the hydrophobic IOLs, although eyes with acrylic hydrophilic IOLs did not require Nd:YAG laser capsulotomy as soon as eyes with acrylic hydrophobic IOLs. There was no difference between the long-term PCO rates when 1- and 3-piece acrylic hydrophobic IOLs were compared or when IOLs made of the same material but with different haptic angles were compared. CONCLUSION: In this study, eyes with acrylic hydrophilic IOLs were more likely to develop PCO than those with acrylic hydrophobic IOLs. The lens design (1-piece versus 3-piece and varying haptic angles) did not affect the PCO rate.     

Posterior dislocation of a plate-haptic silicone intraocular lens with large fixation holes

We present a patient who had uneventful phacoemulsification with in-the- bag implantation of a silicone plate-haptic posterior chamber intraocula r lens (IOL) with 1.15 mm fixation holes. Six months after a neodymium: YAG laser capsulotomy, the IOL spontaneously dislocated posteriorly. A pars plana vitrectomy was performed, the IOL was explanted, and a 3-piece loop-haptic IOL was implanted in the ciliary sulcus. Eight weeks after surgery, best corrected visual acuity was 20/20.