阿奇霉素治疗淋菌性、非淋菌性尿道炎疗效观察

淋病奈瑟氏菌 (NG)解脲支原体 (UU)和沙眼衣原体(CT)是泌尿生殖道的主要病原体 ,在性传播疾病 (STDs)、性传播尿道炎 (STU)中发病率最高。笔者用阿奇霉素对淋病性尿道 (GU)、非淋菌性尿道炎 (NGU) 133例进行治疗 ,现报告如下。1　资料与方法1 1　临床资料　 133例患者来自性病门诊 ,均有不洁性生活史 ,年龄 18～ 6 8岁 ,男 4 8例 ,女 6 2例 ,病程 2～ 6 0天 ,就诊时均取尿道分泌物检查。 133例患者中 ,GU 5 9例 ,NGU5 1例 ,GU合NGU 2 3例 ,其中 :GU +UU 10例 ,GU +CT 9例 ,GU +UU +CT 4例。NGU中 ,CT 2 7例 ,UU 31例 ,C…     

2001-2005年广东省佛山市南海区性病流行病学分析

目的:分析2001-2005年佛山市南海区性病的流行情况。方法:对来自南海区2001-2005年每月上报的性病疫情数据,采用回顾性分析方法。结果:南海区2001-2005年登记上报性病病例21727例,平均年发病率398.90/10万,远高于全省平均水平,且发病率有上升的趋势;男∶女为1∶1.12,男性发病比例呈现上升趋势;病种构成以非淋菌性尿道炎(NGU)、淋病和尖锐湿疣(CA)为主,HIV感染者、性病性淋巴肉芽肿(LGV)、儿童性病发病率呈现增加的趋势。结论:南海区性病发病率明显高于全省平均水平,应进一步加大性病防治工作力度,切实控制性病的蔓延。     

1815例性病患者临床资料分析

为了解性传播疾病(STD)的流行状况,对我院性病门诊2001～2005年1815例性病患者资料总结分析如下。1对象与方法1.1病例来源2001～2005年我院性病门诊初诊确诊为STD患者1815例。对患者的姓名、年龄、性别、婚姻、职业、文化程度、地址、传染来源及症状、体征、实验室检查等资料均建档保存。1.2监测病种对淋病、非淋菌性尿道炎(NGU)、梅毒、尖锐湿疣(CA)、生殖器疱疹(GH)进行监测。1.3诊断标准统一按照卫生部制定的《性病诊断标准与治疗方案》执行。2结果与分析2.1病种构成1815例性病各病种的构成见表1。从表1可见,居第一位的是尖锐湿疣9…     

深圳市2002年性病流行病学分析

目的：了解深圳市2002年性病流行特征，为政府制订预防控制措施提供科学依据。方法：对深圳市2002年性病年报资料及人口数据进行统计分析。结果：深圳市2002年性病报告病例数为12531例，较2001年增长了36．80％，年报告总发病率278．47／10万。艾滋病病毒(HIV)感染者及艾滋病患者(AIDS)报告数成倍增长，非淋菌性尿道炎(NGU)发病率最高，尖锐湿疣位居性病构成第二位，淋病排第三位，仍是性病优势病种，但构成比继续下降。结论：HIV／AIDS、NGU的增长呈明显上升趋势，先天梅毒形势不容乐观，应大力加强对孕妇的产前性病体检工作。     

非淋菌性尿道炎的诊疗进展

非淋菌性尿道炎(NGU)是一种常见的性病。大多数国家早已是NGU占第一位。而且其发病率仍日趋上升，WHO估计全世界每年约有5000万例由沙眼衣原体(CT)引起的NGU，其发病率已超过淋病(2500万)。     

193例非淋菌性尿道炎患者解脲支原体和人型支原体的检测

近年来非淋菌性尿道炎（NGU）的发病率日趋增高，在欧美国家已居性病之首，在我国发病率也呈上升趋势。已经证实，解脲支原体（Uu）和人型支原体（Mh）为NGU的主要病原体之一。我们对193例NGU患者尿道及宫颈分泌物进行了Uu和Mh的分离培养与鉴定，现将结果报道如下。     

广东省江门市新会区2000～2004年性病流行病学分析

目的：分析2000～2004年江门市新会区性病的流行情况。方法：对来自新会区2000～2004年每月上报的性病疫情数据，采用回顾性分析方法。结果：新会区2000～2004年登记上报性病病例7125例，平均年发病率166．95／10万，明显高于全省平均水平，但自2002年起发病率呈逐年下降趋势；男性发病一直高于女性，男：女为2．31：1；病种构成以非淋菌性尿道炎(NGU)、淋病和尖锐湿疣为优势病种；HIV感染者也首次在性病高危人群中被发现。结论：新会区性病发病率近年虽呈下降趋势，但发病率仍明显高于全省水平，应进一步加大性病防治和控制工作力度，切实控制性病的蔓延。     

深圳市性滥妇女性传播感染调查分析

目的：了解深圳市公安局收容教育所性滥妇女性传播感染(STI)情况。方法：收集整理1998～2002年10月深圳市某监测点性滥妇女体检资料及实验室检测资料，并作流行病学分析。结果：在6673例性滥妇女中，共检出性病1396例，检出率为20．92％。其中梅毒检出例数最多，尖锐湿疣、NGU、淋病等次之。结论：性滥妇女性病检出率高，是性病传播的主要传染源，也是性病防治的重点人群，梅毒是当前该地区应重点监控的病种。     

儿童尖锐湿疣28例报告

目的探讨儿童尖锐湿疣（CA）传播途径及防治,促进患儿身心健康发展。方法选取28例在我院门诊就诊的儿童CA患几对其临床表现防治,特别是传播途径与成人的区别进行分析。结果1次治愈7例;2次治愈14例;3次治愈7例,随访3个月、6个月均未见复发。结论儿童CA发生率低,f临床表现及防治,特别是传播途径等方面均与成人有很大区别,对患儿积极治疗定期随访,以减少复发,促进患儿身心健康发展。     

2 182例泌尿生殖道感染的支原体培养及药敏情况分析

为了解本地区支原体感染及耐药情况，我们于2005—2006年对本所性病门诊2182例NGU可疑病例泌尿生殖道标本的支原体培养及药敏试验情况进行统计分析，现报道如下。 1 材料和方法 1．1材料     

Comparative rates of sexually transmitted diseases among heterosexual men, homosexual men, and heterosexual women

The prevalences of several sexually transmitted diseases (STD) among patients attending a public STD clinic were determined in a prospective study. Rates of gonorrhea, syphilis, genital herpes, trichomoniasis, nongonococcal urethritis, pediculosis pubis, scabies, and venereal warts were ascertained according to sex, sexual preference, and race. Numbers of cases of diseases not routinely reported to most public health agencies exceeded numbers of cases of diseases that are routinely reported. Rates of gonorrhea were higher among men than among women and higher among blacks than among whites. Syphilis was most common among homosexual men. Trichomoniasis was three times more frequent among blacks than among whites. Rates of nongonococcal urethritis among heterosexual men were almost twice those among homosexual men. Whites were more likely than blacks to have pediculosis pubis, scabies, and venereal warts. STD not routinely reported to most public health agencies are commonly seen in public clinics, and rates vary according to sex, sexual preference, and race.     

Serotypes of Ureaplasma urealyticum isolated from patients with nongonococcal urethritis and gonorrhea and from asymptomatic urethral carriers

Ureaplasma urealyticum strains isolated from urethral specimens of 112 patients with nongonococcal urethritis, 17 with gonorrhea, and 33 asymptomatic carriers (controls) were tested by the growth-inhibition test with standard ureaplasma antisera (serotypes 1-8). Cases with more than one serotype (two to four types) were encountered in 36.6% of patients with nongonococcal urethritis, 29.4% of those with gonorrhea, and 21.2% of controls. The most frequently recovered serotypes were type 4 from patients with nongonococcal urethritis (57.1%) and type 2 from patients with gonorrhea and controls (35.2% and 36.3%, respectively). The difference in frequency of serotype 4 between patients with nongonococcal urethritis and controls was statistically significant (P less than .001). An additional serotyping with types 9 and 10 antisera of the nontypable strains from patients with nongonococcal urethritis and controls (17.8% and 21.2%, respectively) revealed three type-9 strains. The results show a need for utilization of serotyping of U. urealyticum in studies of the epidemiology and transmissibility of genital infections with U. urealyticum.     

Decision analytic approach to the management of gonorrhea contacts

We used a combination of decision analytic and modeling techniques in constructing a model for study of the management of an asymptomatic woman presenting to a sexually transmitted disease clinic as a contact of a man with gonorrhea. Total cost (physical, emotional, and economic) is expressed in units of dysutility. Initially the probabilities and "costs" of anogenital gonorrhea, incubating syphilis, carriage of the agents of nongonococcal urethritis, and coincident pharyngeal gonorrhea are considered; complications and sequelae are then accounted for. The best strategy is to culture for Neisseria gonorrhoeae, treat immediately with tetracycline, and follow up sexual partners if the culture is positive. Dysutility values calculated for the strategies of just treating with standard regimens of tetracycline, procaine penicillin, or amoxicillin are 288, 310, and 560, respectively. Sensitivity analyses show that the most important factors in determining optimal strategy are the probabilities and costs associated with the patient's carriage of the agents of nongonococcal urethritis. In order for this decision to change, the dysutility value for nongonococcal urethritis would have to decrease to 17% of our best estimate, or the overall prevalence of nongonococcal urethritis would have to be reduced to 16% of our best estimate.     

A study on non-specific urethritis in males

31,042 cases of sexually transmitted disease (STD) were seen among male soldiers at the Command Hospital in Pune during the period 1980-89. All presented with the complaint of urethral discharge with or without dysuria. Among the 4823 cases of urethritis, 3881 men presented with gonorrhea and 942 with nonspecific urethritis. The incidence of nonspecific urethritis was therefore 3.03% of all STDs. 68% of the patients were aged 20-29 years and 72% were single. Urethral discharge was present at the first attendance in 96% of cases. The authors note that among the various types of STDs, the incidence of nonspecific urethritis has risen more rapidly than that of gonorrhea in the world and it is now recognized as the most common STD in Western countries.     

Oral sex as a risk factor for Chlamydia-negative ureaplasma-negative nongonococcal urethritis

We present a case-control study that evaluated the association of Chlamydia-negative, Ureaplasma-negative nongonococcal urethritis with oral and/or anal sex. The study population was composed of 120 patients diagnosed as having nongonococcal urethritis in the Diagnostic Center for sexually transmitted diseases (STD) of the Medical School of Seville. Cases were 56 men suffering from nonogonococcal urethritis from whom neither Chlamydia trachomatis nor Ureaplasma urealyticum was isolated; the remaining 64 males with cultures positive for these agents were considered as controls. Insertive genital-oral intercourse significantly increased the risk of Chlamydia-negative, Ureaplasma-negative nongonococcal urethritis (odds ratio, 11.400; 95% confidence interval, 2.357-75.057). This association was still very strong (odds ratio, 8.882) after adjustment for homosexuality. Insertive anal intercourse appears not to increase the risk of Chlamydia-negative, Ureaplasma-negative nongonococcal urethritis. We conclude that insertive oral sex can be an important risk factor in the development of nongonnococcal urethritis in which the microbial agent is still unknown.     

Predicting subsequent infection in patients attending sexually transmitted disease clinics

OBJECTIVE/GOAL: The objective of this study was to identify characteristics associated with subsequent infection in patients attending a sexually transmitted disease (STD) clinic. STUDY DESIGN: Records were retrospectively reviewed for patients from public STD clinics in 4 cities for 12 months after their initial visit to assess subsequent infection with gonorrhea, chlamydia, mucopurulent cervicitis, nongonococcal urethritis, pelvic inflammatory disease, primary or secondary syphilis, or trichomoniasis. RESULTS: Among 64,463 patients, 33.9% had an initial STD and 7.0% had a subsequent STD. Patients with an initial STD had significantly higher probability of a subsequent STD than patients without (12.0% vs. 4.4%). A subsequent STD was significantly more likely for both sexes for those with an initial STD, who were symptomatic at initial visit, reporting exchange of sex, or under age 20 as well as for men reporting sex with men. CONCLUSIONS: Patients with an initial STD were more likely to return with a subsequent STD. Routinely collected information such as initial diagnosis or age can help identify patients at increased risk of a subsequent STD.     

美国疾病控制中心最新性传播疾病诊断标准与治疗方案介绍

介绍美国疾病控制中心2002年性传播疾病中以尿道炎和宫颈炎为特征的疾病，非淋菌性尿道炎、粘液脓性宫颈炎、衣原体感染、淋球菌感染的诊断标准和治疗方案，以供临床医生在STD诊治中参考。     

前列腺液检测在性病诊断中的应用分析

目的：分析性病患者的确诊过程,总结确诊性病的指标和方法,研究采用前列腺液检测进行判定的准确性。方法：从2012年6月至2013年6月入我院进行性病检查者共153例,从中选取50例,采集其前列腺液,采用三种检测方法,即制作淋球菌涂片,培养和支原体培养,进行阳性检测,对比检测结果。结果：50例受试者中共16例检测出有感染现象,其中有7例淋球菌检测呈阳性确诊为淋病患者,单纯性的非淋球菌性尿道炎患者5例,混合感染患者4例。结论：对于前列腺液的检测可以准确的反映出患者的感染情况,对于性病的进一步确诊有很大的辅助作用,可以尽快的判断患者感染情况,值得推广应用。