医科大学生人格特征与心理健康的相关研究

目的探讨医科大学生人格特征与心理健康的关系.方法采用"中国修订加利福尼亚个性调查表(CPI-RC)"和"症状自评量表(SCL-90)",对110名医科大学生的人格特征和心理健康进行了测量、统计与分析.结果医科大学生人格特征与心理健康呈显著负相关(P＜0.05或P＜0.01).在CPI-RC个性中的好印象、责任心、自我控制、适意感及独立性与心理健康的关系比较明显,智力效率及心理感受性也与个别健康因子相关.心理健康良好组(SCL-90低分组)学生在CPI-RC各量表上的得分普遍高于心理健康较差组(SCL-90高分组)的学生,其中社交风度、自我控制、适意感、智力效率与自我实现5个量表得分差异有显著性(P＜0.05).结论医科大学生的人格特征与心理健康有一定联系,对学生的心理健康可能具有一定的预测作用.     

高中生述情障碍与心理健康的关系研究

目的：探讨高中生述情障碍与心理健康的关系。方法：采用多伦多述情障碍量表(TAS)及症状自评量表(SCL—90)对177名高中生述情障碍和心理健康状况进行测查分析。结果：TAS总分及Ⅰ、Ⅱ、Ⅲ因子均分分别与SCL—90总分及其10个因子均分存有显相关(P＜0．05或P＜0．01)，但与阳性项目数无相关关系(P＞0．05)。结论：高中生述情障碍与心理健康密切相关，心理健康水平在一定程度上取决于述情障碍的水平，述情障碍可能是影响心理健康的个性基础。     

体育专业大学生心理健康与社会支持人格特征的相关研究

目的 探讨体育专业大学生心理健康与社会支持、人格特征的状况及其相关。方法 用症状自评量表(SCL 90)、社会支持问卷(SRRS)和艾森克人格问卷简式量表中国版 (EPQ RSC)对 170名体育专业大学生进行测试。结果 体育专业大学生SCL 90的所有因子得分均低于全国常模 (P<0. 05),最常见的心理问题依次为人际敏感(7. 28% )、敌意 (7. 28% )和强迫症状 (6. 6% )。社会支持和人格特征对心理健康水平具有重要影响。结论 应当重视体育专业大学生的心理健康教育,并充分考虑社会支持和人格特征对其心理健康的影响作用。     

医学生一般自我效能感与心理健康、父母养育方式的相关研究

目的　探讨医学生的一般自我效能感与心理健康状况、父母养育方式之间的关系。方法　用一般效能感量表 (GSES)、症状自评量表 (SCL 90 )及父母养育方式评价量表 (EMBU )对 43 7名广东医学院本科生进行评定。结果　 (1)医学生的一般自我效能感存在着性别差异 ,男生得分显著高于女生。 (2 )医学生在SCL 90的躯体化、抑郁、恐怖、偏执和人际关系敏感等因子上的得分显著低于全国大学生常模 ;男生在SCL 90上的躯体化、强迫、敌对、偏执等因子的得分显著高于女生。 (3 )男生在父母养育方式量表的FF2、FF3、FF5、FF6、MF2、MF5等因子上的得分显著高于女生。 (4 )GSES的得分与SCL 90各因子的得分之间均呈显著的负相关 ;GSES的得分与EMBU中的FF1之间存在极其显著的正相关、与FF6、MF2、MF3、MF4之间存在显著的负相关。结论　医学生的一般自我效能感与心理健康状况、父母养育方式之间存在着一定的关系。     

某大学医学生心理健康状况及其影响因素调查

目的 :调查某大学医学生心理健康状况及其影响因素 ,为提高医学大学生的心理健康水平提供心理学依据。方法 :随机抽取某大学医学生 314人 ,采用精神症状自评量表 (SCL 90 )、艾森克个性问卷 (EPQ)、生活事件调查表 (LES)以及一般情况调查表 ,调查分析医学大学生的心理健康状况及其影响因素。结果 :除躯体化因子外 ,大学医学生SCL 90其余各因子得分均高于全国青年组常模 (P <0 .0 5或 0 .0 1)。是否独生子女、不同家庭气氛学生的心理健康状况差异有统计学意义 (P <0 .0 5 )。逐步回归分析表明 ,负性生活事件分值及EPQ之N分高、家庭气氛不融洽 ,则SCL 90总分高。结论 :社会文化环境中的不良生活事件、情绪不稳定的人格特征、家庭气氛是医学大学生心理健康水平的影响因素之一。     

医科大学生抑郁情绪与自动思维、人格特征关系的研究

目的 探讨自动思维、人格特征与医科大学生抑郁情绪之间的关系.方法 采用抑郁自评量表、自动思维问卷、艾森克人格问卷对1 440名医科大学生进行测量.结果 ①27.5%医科大学生存在着不同程度的抑郁情绪.②抑郁组自动思维、N、P维度得分均显著高于非抑郁组,E、L维度得分显著低于非抑郁组(P＜0.01);不同性格特征个体的抑郁、自动思维存在着显著性差异(P＜0.01).③抑郁与自动思维、N、P呈显著正相关,多元回归分析显示,自动思维、N维度对抑郁的预测力为20.4%.结论 负性自动思维、神经质的人格特征在应激事件和抑郁之间起着重要的中介作用.内向情绪不稳定型人格特征是导致大学生抑郁情绪的易感人格.     

乳腺癌患者心理健康状况的对照研究

目的：了解乳腺癌患者心理健康状况。方法：应用症状自评量表,艾森克个性问卷,生活事件量表对50例乳腺癌患者的心理健康状况进行了检查,并以50名正常人作对照。结果：乳腺癌组SCL－90总分和6个因子分均高于对照组（P＜0．05或P＜0．01）;负性生活事件量表分显著高于对照组（P＜0．05）;EPQ之E因子分低于对照组,N因子分高于对照组（P＜0．01）。结论：乳腺癌患者和的心理健康状况较差。改善乳腺癌患者的心理健康状况,对该病的康复和预后有重要意义。     

医学生个性心理和心理健康状况调查

目的：为掌握在校医学生个性心理和心理健康状况，有针对性地提供心理健康教育和心理健康咨询。方法：采用艾森克人格问卷（EPQ）和症状自评量表SCL－90，对94人进行了测试。结果：EPQ调查，情绪不稳定者42人占51％，SCL－90筛选在躯体化、强迫、人际敏感、抑郁、焦虑等因子中明显高于国内常模有显著性差异P＜0．01，其中强迫因子男生明显高于女生显著性差异P＜0．01。结论：在校生心理健康障碍发生率较高，与学习及就业压力有关。     

社会支持程度对医科大学生自我效能感、考试焦虑及解剖学习成绩的影响

目的 探讨不同社会支持程度对医科大学生自我效能感、考试焦虑及解剖学习成绩的影响.方法 对226名医科大学生进行社会支持量表、一般自我效能感量表、Sarason考试焦虑量表的测评.以社会支持评分为分组依据,社会支持总分<35分为低社会支持组(低分组),>45分为高社会支持组(高分组),进行各量表得分及解剖学习成绩的比较.结果 社会支持高分组医科大学生GSES评分[(29.67±6.57)分]及解剖学习成绩[(78.56±15.74)分],显著高于低分组[(20.47±4.21)分;(67.71±13.92)分];而TAS评分则显著低于低分组,差异有显著性(P<0.01).社会支持高分组医科大学生自我效能感好者显著多于低分组,而自我效能感差者则显著少于低分组;高、中、低度焦虑的发生率两者也有显著性差异;社会支持高分组医科大学生解剖成绩优秀率显著高于低分组,差异有显著性(P<0.05或P<0.01).相关分析显示,社会支持总分及各因子评分与GSES评分、解剖成绩呈显著正相关,而与TAS评分呈显著负相关(P<0.05或P<0.01).结论 医科大学生社会支持程度高者,其自我效能感、解剖学习成绩较高,而考试焦虑程度较低,应采取措施提高医科大学生社会支持程度.     

中职护理藏族生自我效能感、主观幸福感现状及影响因素的研究

目的探究中职护理藏族生自我效能感、主观幸福感现状及影响因素。方法采取随机抽样法,选取82名我校护理专业藏族生作为研究对象,由班主任发放症状自评量表SCL90、自我效能感量表和总体幸福感量表进行填写,并当场回收。将学生症状自评量表SCL90中各项目得分与青年组常模(n=103)进行比较;比较生源地、是否为学生干部、是否为独生子等因素下学生的自我效能感和主观幸福感。结果藏族生与青年组常模在抑郁、焦虑、强迫症状以及恐怖等因子方面差异明显,有统计学意义(P0.05),其他各方面差异不明显,无统计学意义(P 0.05);生源地为城镇的学生自我效能感和主观幸福感均要强于农村的学生,差异有统计学意义(P=0.000);独生子自我效能感要强于非独生子,差异有统计学意义(P=0.029),其他背景下均无明显差异(P 0.05)。结论我校中职护理藏族生自我效能感、主观幸福感均较高,学生生源地和是否是独生子为主要影响因素。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.