微钛钉种植体支抗技术在青少年口腔正畸治疗的应用观察

目的探究青少年口腔正畸治疗中微钛钉种植体支抗技术的应用效果。方法选取本院2015年9月~2016年6月进行口腔正畸治疗的94例青少年患者,随机分为对照组和观察组各47例。对照组患者予以传统非微型种植体支抗治疗,观察组患者予以微钛钉种植体支抗治疗。对比两组临床疗效、治疗后磨牙移位、上中切牙倾斜角与上中切牙凸距差及不良反应发生情况。结果观察组治疗总有效率显著优于对照组,差异有统计学意义(P0.05);治疗后,观察组患者磨牙移位明显小于对照组,上中切牙倾斜角与上中切牙凸距差明显优于对照组,差异有统计学意义(P0.05);观察组不良反应发生率明显低于对照组,差异有统计学意义(P0.05)。结论青少年口腔正畸治疗中微钛钉种植体支抗技术的应用效果显著,安全性较好。     

成人口腔正畸应用微型种植体支抗的效果观察

目的探究微型种植体支抗在成人口腔正畸治疗中应用的临床效果。方法将90例成年口腔正畸患者随机分为两观察组和对照组,每组45例,观察组患者口腔正畸采用微型种植体支抗疗法,对照组口腔正畸采用常规的非种植体支抗疗法,并观察两组经不同口腔正畸疗法治疗后的临床效果。结果两组患者在接受不同的口腔正畸治疗后,统计其治疗效果以及其他指标,观察组显效29例,有效15例,有效率为97.78%;对照组显效20例,有效19例,有效率为86.76%。观察组治疗效果明显优于对照组,两组比较差异有统计学意义(P0.05)。观察组在上中切牙凸距差、磨牙位移、上中切牙倾角差等方面明显优于对照组者,两组相比差异有统计学意义(P0.05)。结论微型种植体支抗在成人口腔正畸治疗中效果显著,值得临床大力推广。     

微型种植体支抗在口腔正畸中的应用探讨

目的探讨微型种植体支抗在口腔正畸治疗中的临床效果。方法选取长沙市口腔医院收治的94例接受口腔正畸治疗的患者,将其随机分为观察组和对照组,每组47例,观察组采用微型种植体支抗治疗,对照组采用口外弓加强支抗治疗,比较两组患者治疗后上中切牙倾斜角差、上中切牙凸距差及磨牙位移的变化情况。结果观察组治疗后上中切牙倾斜角差、上中切牙凸距差均明显高于对照组,两组比较差异有统计学意义(P0.01),且观察组患者治疗后磨牙位移为(3.69±0.29)mm,明显少于对照组,两组比较差异有统计学意义(P0.01)。结论微型种植体支抗在口腔正畸治疗中具有较好的临床效果,且操作简便、创伤小、支抗稳定,值得临床推广使用。     

微型种植体支抗在口腔正畸治疗中的应用

目的探讨微型种植体支抗在口腔正畸治疗中的应用效果。方法对400例接受正畸治疗的患者按治疗方法的不同分为研究组和对照组,每组200例。研究组患者采用微型种植体支抗治疗,对照组患者采用口外弓加强支抗联合横腭杆治疗。观察2组患者治疗9个月后中切牙凸距差、上中切牙倾角差、磨牙位移及满意率、不良反应(水肿、感染、明显不适感)发生率。结果研究组患者满意率明显高于对照组,治疗9个月后中切牙凸距差、上中切牙倾角差均较对照组大,磨牙位移较对照组小(均P<0.05)。2组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论微型种植体支抗在口腔正畸治疗中能够取得较理想的效果,安全性高,值得借鉴。 更多还原     

微型种植体支抗与传统正畸治疗效果比较

目的 观察微型种植体支抗和传统正畸方法在口腔正畸治疗中的效果。方法 选取我院口腔科正畸治疗患者50例,分为对照组和观察组各25例。对照组采取传统正畸治疗,观察组则应用微型种植体支抗治疗,对比分析两组正畸效果。结果 观察组上中切牙突距差、上中切牙倾角、下齿槽座角及尖牙间宽度均明显低于对照组（P<0.05）,磨牙移位距离则较对照组显著下降（P<0.05）;治疗后两组患者咬合力和咀嚼效率均有明显提高（P<0.05）,观察组各指标升高幅度明显高于对照组（P<0.05）;观察组并发症发生率低于对照组（P<0.05）。结论 在口腔正畸治疗中,微型种植体支抗相较于传统正畸方法效果更为显著。     

微型种植体支抗在成人口腔正畸中的应用体会

选取我院口腔科2012年5月~2013年5月收治行成人口腔正畸治疗的患者78例,根据治疗方法不同分为对照组32例和观察组46例。对照组采用传统正畸方法,观察组采用微型种植体支抗疗法,对两组患者的临床治疗效果作回顾性分析与比较。结果观察组临床治疗总有效率、患者总体满意度明显高于对照组,且观察组磨牙位移、上中切牙倾角差度、上中切牙的凸距差度等指标明显优于对照组,组间比较差异均具有统计学意义(P<0.05)。微型种植体支抗应用于成人口腔正畸治疗中的疗效显著,正畸效果佳,值得选用。     

微型种植体支抗与常规矫正在口腔正畸治疗中的临床效果及不良反应发生情况

目的探讨微型种植体支抗与常规矫正在口腔正畸治疗中的临床效果及不良反应发生情况。方法选取我院2017年2月至2019年2月收治的40例行口腔正畸治疗的患者,根据自愿原则将其分为对照组(n=20,常规矫正治疗)和研究组(n=20,微型种植体支抗治疗)。比较两组的牙齿功能、不良反应发生情况及牙周健康指标。结果治疗后,研究组的语言、咀嚼、固体功能评分均明显高于对照组(P<0.05)。研究组不良反应总发生率明显低于对照组(P<0.05)。治疗后,研究组的牙周健康指标均明显优于对照组(P<0.05)。结论在口腔正畸治疗中,采取微型种植体支抗治疗的矫正效果优于常规矫正治疗,且不良反应发生率低。     

微型种植支抗与口外弓加强支抗在口腔正畸治疗中的疗效

目的探讨微型种植支抗与口外弓加强支抗在口腔正畸治疗中的疗效。方法选取2014年3月至2016年3月在该院口腔科准备接受口腔正畸治疗的104例适龄患者,采用随机数字表法将其随机分成微型组和加强组,每组52例。微型组患者采用微型种植支抗技术进行治疗,加强组采用口外弓加强支抗正畸法进行治疗。比较两组患者正畸治疗2年后的治疗成功率、上中切牙凸距差和倾角、磨牙移位、上齿槽和下齿槽座角、尖牙间宽度以及不良反应的发生情况。结果微型组患者经治疗后磨牙移位、上中切牙倾角和凸距差、上齿槽和下齿槽座角和尖牙间宽度等均明显优于加强组,差异有统计学意义(t=29.634,22.216,7.232,7.579,7.365,8.165,P0.001);微型组经治疗后的治疗成功率明显高于加强组,差异有统计学意义(χ~2=8.302,P=0.004);微型组治疗期间不良反应的发生率明显低于加强组,差异有统计学意义(χ~2=10.084,P=0.001)。结论在对口腔畸形患者进行口腔正畸治疗时,微型种植体支抗比口外弓加强支抗在提高治疗成功率、减少术后不良反应等方面更具有优势,值得在临床上推广使用。     

微型种植体支抗正畸对成人安氏Ⅱ类1分类错[牙合]畸形患者牙齿咬合力及龈沟液MMP2、NO水平的影响

目的探讨微型种植体支抗正畸对成人安氏Ⅱ类1分类错[牙合]畸形患者牙齿咬合力及龈沟液MMP2、NO水平的影响。方法选取我院成人安氏Ⅱ类1分类错[牙合]畸形患者97例,采用随机数字表法分为研究组(n=49)、常规组(n=48)。常规组采用口外弓支抗治疗,研究组采用微型种植体支抗正畸,统计比较两组治疗相关指标(上中切牙凸距差、上中切牙倾角差及磨牙移位)、不良反应发生率、矫正前后咀嚼功能、牙齿咬合力、龈沟液基质金属蛋白酶-2(MMP2)、细胞因子细胞间黏附分子1(CAM1)、一氧化氮(NO)水平。结果研究组矫正后咀嚼功能、牙齿咬合力高于常规组,龈沟液MMP2、CAM1、NO水平低于常规组(P<0.05);研究组上中切牙凸距差、上中切牙倾角差高于常规组,磨牙移位小于常规组(P<0.05);研究组不良反应发生率6.12%(3/49)低于常规组20.83%(10/48)(P<0.05)。结论微型种植体支抗正畸可提高成人安氏Ⅱ类1分类错[牙合]畸形患者牙齿咬合力、咀嚼功能,降低龈沟液MMP2、CAM1、NO水平,且安全性高。     

微型种植体改善口腔正畸患者上中切牙唇向移位距离及磨牙位移的临床研究

目的观察研究微型种植体对口腔正畸患者上中切牙唇向移位距离以及磨牙位移的临床效果。方法回顾分析2017年1月~11月期间经我院治疗的口腔正畸患者150例,根据选择矫正方法不同分为观察组和对照组,观察组86例予微型种植体治疗,对照组64例予传统治疗,观察并比对两组经治疗后的上中切牙唇向移位距离以及磨牙位移以及两组并发症发生率。结果观察组治疗后口腔的上中切牙唇向移位距离和磨牙位移较对照组优势显著,差异有统计学意义(P0.05),观察组发生并发症的几率明显低于对照组,差异有统计学意义(P0.05)。结论微型种植体对口腔正畸患者其显著的治疗效果和安全性十分理想,其上中切牙唇向移位距离以及磨牙位移改善更佳,对于口腔正畸患者临床意义重大。     

Determination of creatine kinase isoenzyme MB activity in serum using immunological inhibition of creatine kinase M subunit activity. Activity kinetics and diagnostic significance in myocardial infarction.

This is a new method for the determination of creatine kinase isoenzyme MB activity in serum. The method uses direct activity measurement of creatine kinase B subunit activity after blocking of CK-M subunit activity by inhibiting antibodies. The test takes no longer than 15 min. The method yields an intra-serial C.V. of 2.0-12.9%, and a C.V. from day to day of 5.5%. The detection limit is 3.4 U/l creatine kinase MB. In the 95 cases with proven myocardial infarction several types of creatine kinase MB activity kinetics could be determined. The percentage of creatine kinase MB of peak CK-total is 6-25%, with a mean of 11.1%. The amount of creatine kinase MB with respect to total CK activity after reinfarction is higher than the amount after initial infarction.     

Dissociable correlates of two classes of retrieval processing in prefrontal cortex

Although substantial evidence suggests that the prefrontal cortex (PFC) implements processes that are critical for accurate episodic memory judgments, the specific roles of different PFC subregions remain unclear. Here, we used event-related functional magnetic resonance imaging to distinguish between prefrontal activity related to operations that (1) influence processing of retrieval cues based on current task demands, or (2) are involved in monitoring the outputs of retrieval. Fourteen participants studied auditory words spoken by a male or female speaker and completed memory tests in which the stimuli were unstudied foil words and studied words spoken by either the same speaker at study, or the alternate speaker. On "general" test trials, participants were to determine whether each word was studied, regardless of the voice of the speaker, whereas on "specific" test trials, participants were to additionally distinguish between studied words that were spoken in the same voice or a different voice at study. Thus, on specific test trials, participants were explicitly required to attend to voice information in order to evaluate each test item. Anterior (right BA 10), dorsolateral prefrontal (right BA 46), and inferior frontal (bilateral BA 47/12) regions were more active during specific than during general trials. Activation in anterior and dorsolateral PFC was enhanced during specific test trials even in response to unstudied items, suggesting that activation in these regions was related to the differential processing of retrieval cues in the two tasks. In contrast, differences between specific and general test trials in inferior frontal regions (bilateral BA 47/12) were seen only for studied items, suggesting a role for these regions in post-retrieval monitoring processes. Results from this study are consistent with the idea that different PFC subregions implement distinct, but complementary processes that collectively support accurate episodic memory judgments.     

俯卧位通气对高海拔地区肺复张治疗无效急性呼吸窘迫综合征患者氧合的影响

目的 探讨俯卧位通气对高海拔地区肺复张术(RM)治疗无效急性呼吸窘迫综合征(ARDS)患者的治疗作用.方法 从海拔2260m的地区医院筛选RM治疗无效的41例ARDS患者[平均氧合指数( PaO2/FiO2)较RM前升高＜20％视为RM无效],依不同病因分为肺内源性ARDS组(ARDSp组)和肺外源性ARDS组(ARDSexp组),每组再按信封法随机分为俯卧位组和仰卧位组,即ARDSp俯卧位组(11例)、ARDSp仰卧位组(9例)、ARDSexp俯卧位组(10例)、ARDSexp仰卧位组(11例).在通气前及通气1、2、3、4h监测动脉血氧分压( PaO2)、PaO2/FiO2、静态顺应性(Cst)、气道阻力(Raw)的变化.结果 通气lh时,ARDSexp俯卧位组PaO2/FiO2( mm Hg,l mm Hg=0.133 kPa)即较通气前显著升高(157.4±40.6比129.3±48.7,P＜0.05),并随通气时间延长呈持续增高趋势,4h达峰值(219.1 ±41.1);且ARDSexp俯卧位组通气3h内PaO2/FiO2较其他3组显著增高,另3组间则差异无统计学意义.ARDSp俯卧位组、ARDSexp俯卧位组通气4h时PaO2/FiO2均较相应仰卧位组显著增高(208.8±39.7比127.4±47.1,219.1±41.1比124.9±50.8,均P＜0.05).4组通气前后Cst无显著改变,各组间差异也无统计学意义.ARDSp俯卧位组通气4h时Raw(cmH2O·L-1·s-1)较通气前显著降低(6.8±1.7比10.7±1.8,P＜0.05),且明显低于其他3组;其他3组各时间点Raw组内及组间比较差异均无统计学意义.结论 俯卧位通气作为ARDS机械通气重要策略之一,可以改善RM无效高原ARDS患者的氧合,为抢救患者赢得宝贵的时间.     

Digital imaging among medical facilities

The Department of Veterans Affairs (VA) in the USA operates a network of 172 medical centres which all utilize a hospital information system (HIS) which has been developed and is currently maintained by the VA. During the past several years, an image management and communication module has been developed, installed and clinically utilized at the Washington DC and Maryland VA Medical Centres. This image management and communication system, referred to as the decentralized hospital computer program (DHCP) imaging system, is fully integrated with a commercial picture archiving and communication system (PACS). The system is utilized to capture, archive, and display all images generated within the hospital including radiology, nuclear medicine, pathology, endoscopy, bronchoscopy, and dermatology, intraoperative photographs, ECG data, and a limited number of paper documents. The ultimate goal of the project is to have all patient text and image data available at any clinical workstation to any authorized user anywhere within the network of medical centres. Clinical requirements for an imaging workstation include ease of use, rapid and reliable access to the complete set of patient information, and images which are of acceptable quality to meet the requirements of the user and the subspecialty. Patient confidentiality and data security must be safeguarded at all times. Integration of the images with the remainder of the patient's database was found to be critical to the success of the project. The experience at the Washington and Maryland facilities suggests that an imaging system that is successfully integrated with a hospital information system can provide substantial clinical and economic benefits both within and among medical centres. Clinical acceptance and utilization of the system has been excellent, particularly in diagnostic radiology where DHCP Imaging has been interfaced to a commercial PAC system. Based upon this initial experience, the VA has begun to deploy the system throughout its large network of medical centres.     

Myocardial elastography at both high temporal and spatial resolution for the detection of infarcts

Myocardial elastography is a novel method for noninvasively assessing regional myocardial function, with the advantages of high spatial and temporal resolution and high signal-to-noise ratio (SNR). In this paper, in-vivo experiments were performed in anesthetized normal and infarcted mice (one day after left anterior descending coronary artery [LAD] ligation) using a high-resolution (30 MHz) ultrasound system (Vevo 770, VisualSonics Inc., Toronto, ON, Canada). Radiofrequency (RF) signals of the left ventricle (LV) in longitudinal (long-axis) view and the associated electrocardiogram (ECG) were simultaneously acquired. Using a retrospective ECG gating technique, 2-D full field-of-view RF frames were acquired at an extremely high frame rate (8 kHz) that resulted in high-quality incremental displacement and strain estimation of the myocardium. The incremental results were further accumulated to obtain the cumulative displacements and strains. Two-dimensional and M-mode displacement images and strain images (elastograms), as well as displacement and strain profiles as a function of time, were compared between normal and infarcted mice. Incremental results clearly depicted cardiac events including LV contraction, LV relaxation and isovolumetric phases in both normal and infarcted mice, and also evidently indicated reduced motion and deformation in the infarcted myocardium. The elastograms indicated that the infarcted regions underwent thinning during systole rather than thickening, as in the normal case. The cumulative elastograms were found to have higher elastographic SNR (SNR(e)) than the incremental elastograms (e.g., 10.6 vs. 4.7 in a normal myocardium, and 6.0 vs. 2.4 in an infarcted myocardium). Finally, preliminary statistical results from nine normal (m = 9) and seven infarcted (n = 7) mice indicated the capability of the cumulative strain in differentiating infracted from normal myocardia. In conclusion, myocardial elastography could provide regional strain information at simultaneously high temporal (>/=0.125 ms) and spatial ( approximately 55 microm) resolution as well as high precision ( approximately 0.05 microm displacement). This technique was thus capable of accurately characterizing normal myocardial function throughout an entire cardiac cycle, at the same high resolution, and detecting and localizing myocardial infarction in vivo.     

Clinical Pharmacokinetics of Morphine

Morphine, the most widely used mu-opioid analgesic for acute and chronic pain, is the standard against which new analgesics are measured. A thorough understanding of the pharmacokinetics of morphine is required in order to safely and effectively use this analgesic in a wide variety of patients with different levels of organ function. A MEDLINE search was conducted to identify literature published between 1966 and January 2002 relevant to the pharmacokinetics of morphine. These publications were reviewed and the literature summarized regarding unique and clinically important elements of morphine disposition relative to its parenteral administration (including intravenous, intramuscular, subcutaneous, epidural and intrathecal administration), absorption profile (immediate release, controlled release, and sublingual/buccal, and rectal administration), distribution, and its metabolism/ excretion. Special populations, including infants, elderly, and those with renal/liver failure, have a unique morphine pharmacokinetic profile that must be taken into account in order to maximize analgesic efficacy and reduce the risk of adverse events.