Apnoeic oxygenation in paediatric anaesthesia: a narrative review

Apnoeic oxygenation refers to oxygenation in the absence of any patient or ventilator effort to move the lungs. This phenomenon was first described in humans in the mid-20th century but has seen renewed interest in the last decade following the demonstration of apnoeic oxygenation with low-flow, and subsequently high-flow, nasal oxygen. This narrative review summarises our understanding of apnoeic oxygenation in the paediatric population. We examine the evidence supporting oxygenation via tracheal tube, modified laryngoscopes and nasal cannulae. The evidence for prolongation of safe apnoea time at induction of anaesthesia is also appraised. We explore the capacity for carbon dioxide clearance, flow rate selection with high-flow nasal oxygen and complications associated with the technique. It remains uncertain whether apnoeic oxygenation in paediatric patients results in a meaningful clinical benefit compared with standard care for outcomes such as the number of tracheal intubation attempts or the incidence of hypoxaemia. In particular, the role of apnoeic oxygenation in paediatric difficult airway management is unclear as this has not been the targeted focus of any published research to date.     

Cervical spine clearance: a review

Ethical concerns have hindered any randomised control blinded studies on the imaging required to assess the cervical spine in an unconscious trauma patient. The issue has been contentious for many years and has resulted in burgeoning but inconclusive guidance. MRI and multislice CT technology have made rapid advances, but the literature is slower to catch up. Never the less there appears to be an emerging consensus for the multiply injured patient. The rapid primary clinical survey should be followed by lateral cervical spine, chest and pelvic radiographs. If a patient is unconscious then CT of the brain and at least down to C3 (and in the USA down to D1) has now become routine. The cranio-cervical scans should be a maximum of 2 mm thickness, and probably less, as undisplaced type II peg fractures, can be invisible even on 1 mm slices with reconstructions. If the lateral cervical radiograph and the CT scan are negative, then MRI is the investigation of choice to exclude instability. Patients with focal neurological signs, evidence of cord or disc injury, and patients whose surgery require pre-operative cord assessment should be imaged by MRI. It is also the investigation of choice for evaluating the complications and late sequela of trauma. If the patient is to have an MRI scan, the MR unit must be able to at least do a sagittal STIR sequence of the entire vertebral column to exclude non-contiguous injuries, which, since the advent of MRI, are now known to be relatively common. Any areas of oedema or collapse then require detailed CT evaluation. It is important that cases are handled by a suitably skilled multidisciplinary team, and avoid repeat imaging due to technical inadequacies. The aim of this review is to re-examine the role of cervical spine imaging in the context of new guidelines and technical advances in imaging techniques.     

Novel tubeless supraglottic ventilation in a difficult paediatric airway

Introduction

Discussion and careful planning are essential between surgeon and anaesthesiologist before upper airway surgery, especially in paediatric patients with upper airway obstruction. Tubeless supraglottic ventilation is an accepted technique worldwide.

Risk factors for airway complications during general anaesthesia in paediatric patients

BACKGROUND: Although airway complications are a frequent problem during paediatric anaesthesia, no study has prospectively identified risk factors for adverse respiratory events during airway management when LMA trade mark (laryngeal mask airway), face mask (FM) or a tracheal tube (TT) are used. METHODS: A prospective study was performed at a university hospital's paediatric centre. Preoperative information included recent history of respiratory infection and type of surgery. Intraoperative information included the identification of the device user, the duration of anaesthesia and the type of airway device used. Adverse respiratory events during the perioperative and postoperative periods were registered. One thousand nine hundred and ninety-six patients were included (mean age 6.45 +/- 2.9 years). RESULTS: Airway complications occurred in 10.2% of the patient for LMA (72/704), 4.7% for FM (19/401) and 7.4% (66/891) for TT. Using a stepwise logistic regression, three independent risk factors were identified: age < 6 years, odds ratio (OR) 1.84, 95% CI (1.21-2.80); use of LMA, OR 2.32, 95% CI (1.29-4.17); presence of respiratory infections (RI) before the procedure, OR 3.72, 95% CI (2.3-5.99). CONCLUSIONS: Age < 6 years, recent RI and the use of the LMA were identified as independent factors associated with an increased risk of airway complications.     

Continuous monitoring of oesophageal pH during general anaesthesia with laryngeal mask airway in children

We studied the incidence of gastro-oesophageal reflux (GOR) during general anaesthesia with the laryngeal mask airway (LMA) in a paediatric population with two ventilatory regimes: spontaneous breathing and controlled mechanical ventilation (CMV). Thirty children between 6 months and 15 years, ASA I-II, for routine surgery, were randomly assigned in two groups: spontaneous ventilation (n=14), and CMV (n=16). A pH probe was situated in the central third of the oesophagus. Some 66% of the patients breathing spontaneously had GOR episodes vs. 92% of the patients with CMV (P < 0,01). Reflux took place mainly after LMA removal (21% vs. 68%; P < 0,01) and in the Postanaesthetic Care Unit (PACU) (29% vs. 43%; P < 0,05). There was a high incidence of GOR during general anaesthesia and in the PACU in paediatric patients anaesthetized with the LMA. GOR episodes were significantly more evident in the CMV group, mainly after LMA removal, but without clinical significance.     

Bilateral vocal cord paralysis after anterior cervical discoidectomy and fusion in a case of whiplash cervical spine injury: a case report

BACKGROUND

Bilateral vocal cord paralysis is a risk of anterior cervical discoidectomy and fusion. We discuss the mechanism of vocal cord paralysis and the precautions necessary to avoid this catastrophic complication. A rare case of bilateral vocal cord paralysis after anterior cervical discoidectomy and fusion (ACD/F) is reported.

CASE DESCRIPTION

The patient, a 37-year-old male, was paraplegic, had bilateral intrinsic hand muscle weakness and sphincter involvement following a whiplash cervical spinal injury. A C5-C6 ACD/F for traumatic C5-C6 disc prolapse was performed. On the third postoperative day, he developed difficulty in coughing and a husky voice. Otolaryngological evaluation revealed bilateral vocal cord paralysis. He later required a tracheostomy that partially alleviated his major symptoms.

CONCLUSION

In patients undergoing ACD/F, a mandatory preoperative evaluation of the vocal cords should be performed. An appropriate modification in surgical planning should be made if vocal cord palsy is diagnosed preoperatively to prevent bilateral vocal cord paralysis. Proper and judicious use of Cloward retractors is advocated.     

The laryngeal mask airway in paediatric anaesthesia

Forty-eight children, aged between 2 and 10 years, admitted as day cases for otological surgery were allocated at random into two groups. The first group was anaesthetised using a standard facemask, and the second with a laryngeal mask airway. The laryngeal airway produced a satisfactory airway in all children, and was inserted on the first attempt in 67% of patients. Hypoxia was significantly less frequent in the laryngeal airway group (p less than 0.05), and there were significantly fewer interruptions to surgery than in the facemask group (p less than 0.001). Patient safety, operating and anaesthetic conditions were all considered superior in the laryngeal airway group.     

Cervical spine disease and anaesthesia

Surgery on the cervical spine is commonly performed to relieve compression of the spinal cord (myelopathy), a nerve root (radiculopathy) or to provide bony stabilization to prevent secondary neurological injury. The pathological causes of myelopathy and radiculopathy are a common consequence of osteoarthritis or less commonly due to disc herniation, tumours, trauma, infection and multisystem disease, and in some conditions as a result of their associated pathologically or surgically induced instability. Successful anaesthetic management should involve a meticulous preoperative assessment of the patient's airway, a systemic review especially in patients with comorbidities and multisystem disease, and attention to their medication and analgesic requirements. Preoperative discussion with the surgical team allows planning of airway management, patient positioning, cardiovascular support (in cases with the potential for significant blood loss), the availability of appropriate blood products and monitoring, postoperative pain management and ward destination.     

Cervical spine disease and anaesthesia

Surgery on the cervical spine is commonly performed to relieve compression of the spinal cord (myelopathy), a nerve root (radiculopathy) or to provide bony stabilization to prevent secondary neurological injury. The pathological causes of myelopathy and radiculopathy are a common consequence of osteoarthritis or less commonly due to disc herniation, tumours, trauma, infection and multisystem disease, and in some conditions as a result of their associated pathologically or surgically induced instability. Successful anaesthetic management should involve a meticulous preoperative assessment of the patient’s airway, a systemic review especially in patients with comorbidities and multisystem disease, and attention to their medication and analgesic requirements. Preoperative discussion with the surgical team allows planning of airway management, patient positioning, cardiovascular support (in cases with the potential for significant blood loss), the availability of appropriate blood products and monitoring, postoperative pain management and ward destination.     

Cervical spine disease and anaesthesia

Surgery on the cervical spine is commonly performed to relieve compression of the spinal cord (myelopathy), a nerve root (radiculopathy) or to provide bony stabilization to prevent secondary neurological injury. The pathological causes of myelopathy and radiculopathy are a common consequence of osteoarthritis or less commonly due to tumours, trauma, disc herniation, infection and multisystem disease, and in some conditions as a result of their associated pathologically or surgically induced instability. Successful anaesthetic management should involve a meticulous preoperative assessment of the patient’s airway, a systemic review especially in patients with comorbidities and multisystem disease, and attention to their medication and analgesic requirements. Preoperative discussion with the surgical team allows planning of airway management, patient positioning, cardiovascular support (in cases with the potential for significant blood loss), the availability of appropriate blood products and monitoring, postoperative pain management and ward destination.     

Cervical spine disease and anaesthesia

Surgery on the cervical spine is commonly performed to relieve compression of the spinal cord (myelopathy), a nerve root (radiculopathy) or to provide bony stabilization to prevent secondary neurological injury. The pathological causes of myelopathy and radiculopathy are a common consequence of osteoarthritis or less commonly due to disc herniation, tumours, trauma, infection and multisystem disease, and in some conditions as a result of their associated pathologically or surgically induced instability. Successful anaesthetic management should involve a meticulous preoperative assessment of the patient’s airway, a systemic review especially in patients with comorbidities and multisystem disease, and attention to their medication and analgesic requirements. Preoperative discussion with the surgical team allows planning of airway management, patient positioning, cardiovascular support (in cases with the potential for significant blood loss), the availability of appropriate blood products and monitoring, postoperative pain management and ward destination.     

Pressure versus volume-controlled ventilation with a laryngeal mask airway™ in paediatric patients

BACKGROUND: The utility of positive pressure ventilation with the laryngeal mask airway (LMA) in children was described previously, but the possibility of gastric insufflation, related to high peak airway pressure, continues to be a disadvantage. In this prospective study, inspiratory pressures, air leak and signs of gastric insufflation were compared between volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) using an LMA. METHODS: Thirty-two ASA I patients, aged 4.5 +/- 4 years, who were scheduled for elective procedures under combined general anaesthesia and caudal analgesia, were enrolled. After inhalation induction and LMA insertion, each patient was randomly assigned to receive successively PCV and VCV. Peak pressures (PCV) and tidal volumes (VCV) were changed in order to achieve adequate ventilation [endtidal CO2 5-5.4 kPa (38-42 mmHg)]. RESULTS: Peak airway pressures were significantly lower with PCV than VCV (14.1 +/- 1.6 cmH2O versus 16.7 +/- 2.3 cmH2O, P < 0.001). No patient ventilated with PCV required peak pressure higher than 20 cmH2O compared with six patients ventilated with VCV (P < 0.05). Haemodynamic parameters, expiratory tidal volume and percent of leak were similar in both ventilatory modes and no signs of gastric insufflation were detected. CONCLUSIONS: During general anaesthesia in children using an LMA, PCV offers lower peak inspiratory airway pressures while maintaining equal ventilation compared with VCV. Although no signs of gastric insufflation were detected in both groups, the lower pressures might be significant in patients with reduced chest wall or lung compliance.     

Sedation and regional anaesthesia in the adult patient

This review discusses sedation for regional anaesthesia in the adult population. The first section deals with general aspects of sedation and shows that the majority of patients receiving sedation for regional anaesthesia are satisfied and would choose it again. Methods of assessing the level of sedation are discussed with emphasis on clinical measures. The pharmacology of the drugs involved in sedation is discussed, with propofol and remifentanil appearing to be the combination of choice for sedation in regional anaesthesia. The techniques for administering sedation are discussed and replacement of the traditional repeated boluses or continuous infusion with pharmacokinetic and patient-controlled systems is supported. Patient satisfaction studies suggest that patient-controlled systems are preferred.     

Usefulness of self made introducer for laryngeal mask airway in paediatric anaesthesia

The usefulness of a self made introducer for laryngeal mask airway (LMA) placement was investigated in 251 paediatric patients. Adequate success rate on the first attempt and atraumatic insertions were achieved by the introducer with minimum experience. The authors concluded that the introducer has significant advantages for easy and safe insertions of the LMA in paediatric anaesthesia.     

Anterior instrumentation in thetreatment of lower cervical spine injuries

Anterior cervical instrumentation is a valuable adjunct to bony fusion techniques in obtaining internal stability to thecervical spine following trauma. Anterior plate fixator may obviate the need for a subsequent posterior procedure in cases of associated posterior cervical ligamentous instability, decrease the potential for loss of alignment or deformity, prevent graft dislodgment, and minimize the need for restrictive external immobilization for easier rehabilitation.     

Special considerations in paediatric intensive care

Paediatric intensive care units (PICU) provide care to the most critically ill or injured children. Children are admitted to PICU with a wide variety of illnesses, injuries and following a range of surgical procedures. High staff-to-patient ratios are required both because of the potentially rapid evolution of critical illness in children, as well as the complexity of the supportive therapies offered. Definitive evidence for specific paediatric therapies is often limited with extrapolation taken from adult experience, but there are increasing international collaborative efforts that have produced consensus treatment guidelines that serve to promote the use of best practice therapies. This article reviews therapies and techniques that define care in the PICU and in particular outline principles of management of acute respiratory distress syndrome (ARDS), septic shock and traumatic brain injury (TBI). Neonatal and cardiac intensive care medicine topics are outside the scope of this article.     

Traumatic posterior atlantooccipital dislocation with Jefferson fracture and fracture-dislocation of C6-C7: a case report with survival

Atlantooccipital dislocation (AOD) is a rare and usually fatal injury. In the current study, the authors reported an extremely rare case of posterior AOD with Jefferson fracture and fracture-dislocation of C6-C7. The patient survived the injury and had only incomplete quadriplegia below the C7 segment with anterior cord syndrome. He was successfully managed with in situ occipitocervical fusion using the Cotrel-Dubousset rod system, corpectomy of C6, and anterior interbody fusion of C5-C7 with plating. To our knowledge, this is the first report of posterior AOD with two other non-contiguous cervical spine injuries. A high index of suspicion and careful examination of the upper cervical spine should be considered as the key to the diagnosis of AOD in cases that involve multiple or lower cervical spine injuries.