中药外治法用于盆腔炎性疾病后遗症的疗效探讨

Objective To explore the curative effect of treating sequelae of pelvic inflammatory disease with chinese medicine external therapy.Metbods 178 cases that diagnosed as sequelae of pelvic inflammatory disease were randomly divided into control group,test Group 1,and test Group 2.Control group were treated by with broad-spectrum antibioticos for three cycles cycles intravenously;and applying Chinese medicine retention enema and Chinese medicine abdominal hot compress on test Group 1 for three cycles;test Group 2 was used the same methods as group 1 for six cycles.Comparing the comprehensive effect,cure rate and the recurrence rate within the six-month after the treatment.Results Comparing the integrated effect of the three groups;test groups 2 was the optimal(P＜0.01).The cure rates of control group,test Group 1,and test Group 2 were19%34%61%respective;and the recurrence rates were 55%,35%,12%respectively.There were statistically significant differences among these three groups(P＜0.01);test group 2 had the highest cure rate and the lowest recurrence rate;and control group had the opposite results.Conchusion Applying Chinese medicine retention enema and abdominal Chinese medicine hot compress on sequelae of pelvic inflammatory disease for 6 cycles has remarkable treatment effect.     

中药外治法用于盆腔炎性疾病后遗症的疗效探讨

Objective To explore the curative effect of treating sequelae of pelvic inflammatory disease with chinese medicine external therapy.Metbods 178 cases that diagnosed as sequelae of pelvic inflammatory disease were randomly divided into control group,test Group 1,and test Group 2.Control group were treated by with broad-spectrum antibioticos for three cycles cycles intravenously;and applying Chinese medicine retention enema and Chinese medicine abdominal hot compress on test Group 1 for three cycles;test Group 2 was used the same methods as group 1 for six cycles.Comparing the comprehensive effect,cure rate and the recurrence rate within the six-month after the treatment.Results Comparing the integrated effect of the three groups;test groups 2 was the optimal(P＜0.01).The cure rates of control group,test Group 1,and test Group 2 were19%34%61%respective;and the recurrence rates were 55%,35%,12%respectively.There were statistically significant differences among these three groups(P＜0.01);test group 2 had the highest cure rate and the lowest recurrence rate;and control group had the opposite results.Conchusion Applying Chinese medicine retention enema and abdominal Chinese medicine hot compress on sequelae of pelvic inflammatory disease for 6 cycles has remarkable treatment effect.     

3种药物治疗妊娠中期外阴阴道假丝酵母菌病的疗效比较

Objective To observe the clinical therapeutic effect of the treatment on vulvovaginal candidiasis (VVC) in the mid trimester of pregnancy with three species of drug (Clotrimazole,Macmirorcomplex, Baofukang Shuan). Methods 83 women diagnosed with VVC in the mid trimester of pregnancy were divided into three groups: Group A with 30 cases, treated with Clotrimazole for twice; Group B with 28 cases, treated with Macmirorcomplex for 6 days; Group C with 25 cases, treated with Baofukang Shuan for 8 days. Observed the clinical effect, the microbes therapeutic effect and the adverse effect of the treatment with three species of drug. Results (1)The clinical cure rate of Group A was 86.67% and the fungal negative rate was 93.33%. The clinical cure rate of Group B was 57.14% and the fungal negative rate was 75%. The clinical cure rate of Group C was 60% and the fungal negative rate was 40%. There were no adverse effect to be found in the three groups. (2) The clinical cure rate and curative rate of Group A were significantly higher than those of Group B and Group C( P＜0,05 ),but there were no difference in Group B and Group C ( P＞ 0.05 ). The V VC scores of the three groups were significantly descended compared with those of pretherapy ( P＜ 0.01 ), but there were no difference of the curative rate about microbes therapeutic effect in the three groups ( P＞ 0.05 ).Conclusion The three drugs for VVC in pregnancy are all effective and no serious adverse effect. Clotrimazole has better clinical therapeutic effect than Macmirorcomplex and Baofukang Shuan.     

痛风消汤治疗急性痛风性关节炎36例临床观察

Objective To observe the effect of self mading Tongfengxiao decoction in treatment of acute gouty arthritis. Methods 69 patients were randomly divided into two groups. In the control group,33 patients were given diclofenac sodium sustained-release capsules and allopurinol treatment;In treatment group ,36 patients were given to the self mading Tongfengxiao decoction in addition to the western medicine received by the control group. The two groups were all treated for 14 days. Results The total effective rate was 94.4% for treatment group and 87.8% for control group respectively. Therefore, the difference of treatment effect between twp groups was significant ( P ＜0. 05 ) ;Also, the treatment group performed better than control group in term of reducing serum uric acid( P ＜ 0. 05).Conclusion The treatment of Tongfengxiao decoction combined western medicine for acute gouty arthritis had a good synergistic effect, and could reduce serum uric acid and improve clinical symptoms.     

前列腺素E1联合血浆置换治疗慢性重型肝炎的临床研究

Objective To investigate the curative effect, timing and feasibility of prostaglandin E1 combined plasma exchange in treatment of chronic severe hepatitis. Methods Eighty-eight patients with chronic severe hepatitis were randomly divided into treatment group and control group. The treatment group was given prostaglandin E1 combined plasma exchange treatment based on the comprehensive treatment of internal medicine. Control group only had given the internal medicine comprehensive treatment. Results The symptoms and signs of the treatment group were improved after treatments, especially with total bilirubin, cholinesterase, prothrombin activity, NH3 ( P ＜ 0.01,P ＜ 0.05 ). After treatment, except for albumin, the others indicators of the two groups had significant difference ( P ＜ 0.05). Follow-up for three months, the total effective rate of the treatment group was 69.6% ( 32cases ), early effective rate was 79.3% (23 cases), mid-term effective rate was 64.3% (9 cases) were all significantly higher than those of control group [47.6% (20 cases), 55.6% ( 15 cases), 38.5% (5 cases)] (P ＜ 0. 01 ).Conclusion Prostaglandin E1 combined with plasma exchange in treatment of chronic severe hepatitis can improve the liver function and survival rate significantly.     

前列腺素E1联合血浆置换治疗慢性重型肝炎的临床研究

Objective To investigate the curative effect, timing and feasibility of prostaglandin E1 combined plasma exchange in treatment of chronic severe hepatitis. Methods Eighty-eight patients with chronic severe hepatitis were randomly divided into treatment group and control group. The treatment group was given prostaglandin E1 combined plasma exchange treatment based on the comprehensive treatment of internal medicine. Control group only had given the internal medicine comprehensive treatment. Results The symptoms and signs of the treatment group were improved after treatments, especially with total bilirubin, cholinesterase, prothrombin activity, NH3 ( P ＜ 0.01,P ＜ 0.05 ). After treatment, except for albumin, the others indicators of the two groups had significant difference ( P ＜ 0.05). Follow-up for three months, the total effective rate of the treatment group was 69.6% ( 32cases ), early effective rate was 79.3% (23 cases), mid-term effective rate was 64.3% (9 cases) were all significantly higher than those of control group [47.6% (20 cases), 55.6% ( 15 cases), 38.5% (5 cases)] (P ＜ 0. 01 ).Conclusion Prostaglandin E1 combined with plasma exchange in treatment of chronic severe hepatitis can improve the liver function and survival rate significantly.     

子宫内膜异位症术后辅助药物治疗的临床研究

Objective To study the clinical effects and safety of mifepristone and gestrinone as postoperative auxiliary medicine to patients with endometriosis.Methods 120 patients were randomly divided into postoperation with mife~stone group,postoperation with gestrinone group and non-postoperation medicine group,40 cages for each group.A retrospective analysis was carried out to compare the clinical effects,adverse drug reaction and relapse conditions:Results The symptom of patients in all groups was impmved with remission in various degree.The adverse reaction of mifcpristone group was less than that of gestrinone group.And there was no significant difference in curative effects in these two groups(P＞0.05).But the curative effects of mffepristone and gestrinone groups were significantly better than that of nonpostoperation medicine group(P＞0.05).The recurrence rates of mifepristone,gestrinorle and nonpostoperatlon medicine groups were 15%.12.5%and 30%respectively.Conclusion It showed that the mlfepristone and gestdnone used as postoperative auxiliary medicine to patients with endometrinsis have the advantages of economic and practical,safe.effective,less adverse reaction,and can obviously reduce the recurrence rate,which is a effective method,     

子宫内膜异位症术后辅助药物治疗的临床研究

Objective To study the clinical effects and safety of mifepristone and gestrinone as postoperative auxiliary medicine to patients with endometriosis.Methods 120 patients were randomly divided into postoperation with mife~stone group,postoperation with gestrinone group and non-postoperation medicine group,40 cages for each group.A retrospective analysis was carried out to compare the clinical effects,adverse drug reaction and relapse conditions:Results The symptom of patients in all groups was impmved with remission in various degree.The adverse reaction of mifcpristone group was less than that of gestrinone group.And there was no significant difference in curative effects in these two groups(P＞0.05).But the curative effects of mffepristone and gestrinone groups were significantly better than that of nonpostoperation medicine group(P＞0.05).The recurrence rates of mifepristone,gestrinorle and nonpostoperatlon medicine groups were 15%.12.5%and 30%respectively.Conclusion It showed that the mlfepristone and gestdnone used as postoperative auxiliary medicine to patients with endometrinsis have the advantages of economic and practical,safe.effective,less adverse reaction,and can obviously reduce the recurrence rate,which is a effective method,     

子宫内膜异位症术后辅助药物治疗的临床研究

Objective To study the clinical effects and safety of mifepristone and gestrinone as postoperative auxiliary medicine to patients with endometriosis.Methods 120 patients were randomly divided into postoperation with mife~stone group,postoperation with gestrinone group and non-postoperation medicine group,40 cages for each group.A retrospective analysis was carried out to compare the clinical effects,adverse drug reaction and relapse conditions:Results The symptom of patients in all groups was impmved with remission in various degree.The adverse reaction of mifcpristone group was less than that of gestrinone group.And there was no significant difference in curative effects in these two groups(P＞0.05).But the curative effects of mffepristone and gestrinone groups were significantly better than that of nonpostoperation medicine group(P＞0.05).The recurrence rates of mifepristone,gestrinorle and nonpostoperatlon medicine groups were 15%.12.5%and 30%respectively.Conclusion It showed that the mlfepristone and gestdnone used as postoperative auxiliary medicine to patients with endometrinsis have the advantages of economic and practical,safe.effective,less adverse reaction,and can obviously reduce the recurrence rate,which is a effective method,     

氟伐他汀对缺血性脑卒中患者的疗效观察及护理措施

Objective To explore the effect and nursing main points of fluvastatin on the patients with cerebral arterial thrombosis. Methods Eighty-five patients with cerebral arterial thrombosis were randomly divided into three groups. Group Ⅰ was the negative control group. Group Ⅱ was the conventional-dose therapy group and group Ⅲ was the high-dose therapy group. Each group was treated with related therapy and care. The blood lipids in all groups were tested before the treatment, 4 weeks, 12 weeks and 24 weeks after the treatment; the carotid intima-media thickness (IMT) were measured by the Germany SEQUOIAS-512-B ultra machine before the treatment and 24 weeks after the treatment; At the same time, the side effects of fluvastatin were recorded. Results The results of blood lipid tests showed that the LDL, TC and TG in two treated groups were significantly decreased compared to negative control group (P<0.05). After treated for 24 weeks, the carotid intima-media thickness (IMT) in two treated groups were significantly reduced (P<0.05); the side effects of fluvastatin were infrequent and there was no significant different among the three groups (P>0.05). Conclusion The effects of different doses of fluvastatin on cerebral arterial thrombosis were significantly different. With the dose of fluvastatin increased, the serum LDL-L and TC reduced more obvious and the inhibition on carotid atherosclerosis shows more obvious, and the side effects did not increased.     

子宫中隔切除术后预防粘连方法探讨

目的 探讨子宫中隔并不孕患者宫腔镜术后不同处理方法预防宫腔粘连的效果.方法 55例子宫中隔并不孕患者行腹腔镜监护下宫腔镜子宫中隔切除术(TCRS),术后针对不同患者采用不同术后处理措施,包括宫腔放置与不放IUD,是否进行人工周期治疗,部分患者术后使用GnRH-a类药物治疗术后第1、3个月行宫腔镜检查随访,宫内放置IUD的患者;于术后第3个月取环.结果 54例患者术后进行宫腔镜检查随访,其中40例分别于术后第1、3个月完成了术后2次宫腔镜检查,另14例只完成一次检查.宫腔术后放环与否对术后宫腔形态影响无差异(P>0.05),术后使用人工周期治疗患者较未使用者子宫内膜厚,此两者术后第3个月宫腔镜检查发现宫底创面均已有内膜覆盖.使用GnRH-a类药物患者术后官腔形态满意.结论 TCRS术后宫腔放置IUD无助于预防术后粘连的发生;术后人工周期治疗应更个体化并有针对性的使用GnRH-a类药物治疗.术后及时进行宫腔镜检查随访可防止术后宫底新粘连的形成.     

10例狂犬病误诊原因分析

狂犬病近年来发病率有逐年增加的趋势,近十二年来,我们共遇见狂大病２３例,其中１０例被误诊为其它疾病,现就其误诊原因进行分析如下。１临床资料１．１ 一般资料：男８例,女２例;年龄最大７８岁,最小４岁。发病季节为３月～１１月。首诊科室,儿科３例、内科３例、转院３例、急诊科１例。１．２ 临床表现：发热７例,恐风５例,恐水６例,怕光３例,流涎１０例,胸闷、气促、呼吸困难４例,烦躁不安１０例,多汗７例,恐惧６例,肢体麻木４例,抽搐４例,恶心、呕吐２例,昏厥１例。所有病例发病至死亡时间为２天～６天,死亡原因为…     

住院患者精神用药情况调查分析

目的：了解目前住院精神患者的药物使用情况。方法：采用一日法调查西安市精神卫生中心403例住院精神患者诊断和治疗情况，并与上海市精神卫生中心2004年调查结果相比较。结果：①传统精神药物使用显著减少，新型精神药物使用占据首位；②抗精神病药物使用趋向小剂量化；③本组联用丙戊酸盐类药物显著增多；④我院精神药物使用情况与上海精神卫生中心比较有显著差异。结论：近年来精神药物使用情况已发生了显著变化，与新型精神药物疗效好，副作用少，患者依从性高有关。     

不同方法治疗慢性宫颈炎的疗效分析

目的慢性宫颈炎是妇科最常见的疾病之一,可引起盆腔脏器炎症,并且与宫颈癌的发生关系密切。本文诣在探讨不同方法在慢性宫颈炎中的疗效。方法回顾性分析新乡市中心医院收治的210例宫颈炎患者,采用药物保妇康栓、聚焦超声治疗及宫腔镜下宫颈电切术的临床效果进行统计分析。结果宫颈电切术治疗有效率为97.9%,明显高于另外两组,差异有统计学意义。结论宫腔镜下宫颈电切术治愈慢性宫颈炎,并且切除宫颈移行带,减少宫颈癌发生。     

欧洲药典适用性认证介绍

目的介绍欧洲药典适用性认证程序,为国内药品监管机构和原料药生产企业提供信息,促进我国原料药生产企业的国际化。方法通过查阅调研欧盟相关药品法规和与EDQM同行面对面的交流,详细了解欧洲药典适用性认证的组织机构和具体程序。结果与结论欧洲药典适用性认证程序在对原料药的质量控制有重要作用,加强了药典的监管力度,进一步保证了原料药的质量、安全性和有效性。     

新疆维吾尔自治区基层医院平均住院日调查分析

目的 通过对新疆维吾尔自治区14个县乡级医疗机构住院患者平均住院日及影响因素进行分析,为县乡级医疗机构进一步提高医疗管理质量提供依据.方法 将2009-2010年1504例县乡级医院住院患者平均住院天数,按性别、年龄、院别、付费方式、疾病分类进行描述性统计和秩和检验分析.结果 不同性别间及院别间平均住院日差异均有统计学意义(均P＜0.05),男性平均住院日为10.39 d,女性为8.69d,乡级医院为9.27d,县级医院为9.50 d.不同年龄间平均住院日差异有统计学意义(P＜0.05),小于15岁组、15 ～24岁组、25～44岁组、45 ～65岁组、大干65岁组平均住院日分别为8.10 d、7.66d、8.83 d、10.26 d和11.33 d.自费患者平均住院日为8.39 d,新农合组为9.10 d,商业保险组10.17 d,社会基本医疗保险患者则为11.08 d.不同疾病分类间平均住院日差异明显,妊娠类平均住院日最短,为6.73 d,而肿瘤患者则为14.26 d.结论 不同性别、不同年龄段、不同疾病分类及不同付费方式间平均住院日存在差异,县级医疗机构和乡级医疗机构住院患者平均住院日也存在差异.     

The effect of temperature and of cetrimide on the rate of loss of refractility of spores of Bacillus megaterium

The rate of germination of spores of Bacillus megaterium at 30° is not significantly different from the rate at 37° but the onset of germination is delayed; outgrowth is normal. At 45° germination of some spores occurs but the rate is much slower than at 37°, and there is no lag; emergence occurs from only a proportion of the germinated spores and after 3 or 4 vegetative cells have been produced, replication ceases. A single regression equation can represent the germination rate of the spores at 37° in the presence of from 0.0005 to 0.02% w/v of cetrimide and in its absence. In 0.0005% w/v of cetrimide, germ cells emerge from some of the germinated spores but many of them become swollen and disintegrate. Concentrations of 0.00125% w/v or more progressively inhibit swelling and completely inhibit emergence.     

经尿道前列腺汽化电切术与经尿道前列腺电切术治疗前列腺增生症的效果对比

目的 对比分析经尿道前列腺汽化电切术与经尿道前列腺电切术治疗前列腺增生症的效果.方法 将本院2011年3月～2013年2月收治的90例前列腺增生症患者随机分为观察组（n=45）和对照组（n=45）,观察组患者采用经尿道前列腺汽化电切术治疗,对照组患者采用尿道前列腺电切术治疗,比较两组患者的疗效.结果 观察组的手术时间、术中出血量、术后冲洗时间、术后留置导尿管时间、住院时间少于对照组（P＜0.05）,残余尿量、国际前列腺症状评分和生活质量评分优于对照组（P＜0.05）,但是两组患者的并发症发生率差异无统计学意义（P＞0.05）.结论 经尿道前列腺汽化电切术治疗前列腺增生症具有疗效更确切、出血少、恢复快等优势,可以作为治疗前列腺增生症的首选方法.     

甲巯咪唑治疗甲状腺功能亢进症致白细胞减少12例临床分析

目的探讨甲巯咪唑治疗甲状腺功能亢进症引起白细胞减少的规律及治疗对策。方法回顾分析本院2007年2月至2012年2月使用甲巯咪唑治疗甲状腺功能亢进症致白细胞减少12例的临床资料。结果 75%（9/12）的病例白细胞减少发生在治疗开始的第2～3个月;全部病例白细胞减少均发生在甲巯咪唑15～45mg/d治疗阶段;口服抗白细胞减少药物及皮下注射重组人粒细胞集落刺激因子治疗的有效率为83.3%（10/12）。结论甲巯咪唑药物可导致白细胞减少、粒细胞减少;用药前后应密切监测血常规,掌握白细胞减少的情况,如明显减少应及时停药,予以升白细胞药物对症治疗,必要时给予重组人粒细胞集落刺激因子皮下注射治疗。