共查询到20条相似文献,搜索用时 0 毫秒
1.
Donghee Kim Nia Adeniji Nyann Latt Sonal Kumar Patricia P. Bloom Elizabeth S. Aby Ponni Perumalswami Marina Roytman Michael Li Alexander S. Vogel Andreea M. Catana Kara Wegermann Rotonya M. Carr Costica Aloman Vincent L. Chen Atoosa Rabiee Brett Sadowski Veronica Nguyen Renumathy Dhanasekaran 《Clinical gastroenterology and hepatology》2021,19(7):1469-1479.e19
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
Alexandra E. Livanos Divya Jha Francesca Cossarini Ana S. Gonzalez-Reiche Minami Tokuyama Teresa Aydillo Tommaso L. Parigi Mark S. Ladinsky Irene Ramos Katie Dunleavy Brian Lee Rebekah E. Dixon Steven T. Chen Gustavo Martinez-Delgado Satish Nagula Emily A. Bruce Huaibin M. Ko Benjamin S. Glicksberg Saurabh Mehandru 《Gastroenterology》2021,160(7):2435-2450.e34
15.
Craig S. Broberg Adrienne H. Kovacs Soraya Sadeghi Marlon S. Rosenbaum Matthew J. Lewis Matthew R. Carazo Fred H. Rodriguez Dan G. Halpern Jodi Feinberg Francisca Arancibia Galilea Fernando Baraona Ari M. Cedars Jong M. Ko Prashob Porayette Jennifer Maldonado Berardo Sarubbi Flavia Fusco Alexandra A. Frogoudaki Jamil A. Aboulhosn 《Journal of the American College of Cardiology》2021,77(13):1644-1655
BackgroundAdults with congenital heart disease (CHD) have been considered potentially high risk for novel coronavirus disease-19 (COVID-19) mortality or other complications.ObjectivesThis study sought to define the impact of COVID-19 in adults with CHD and to identify risk factors associated with adverse outcomes.MethodsAdults (age 18 years or older) with CHD and with confirmed or clinically suspected COVID-19 were included from CHD centers worldwide. Data collection included anatomic diagnosis and subsequent interventions, comorbidities, medications, echocardiographic findings, presenting symptoms, course of illness, and outcomes. Predictors of death or severe infection were determined.ResultsFrom 58 adult CHD centers, the study included 1,044 infected patients (age: 35.1 ± 13.0 years; range 18 to 86 years; 51% women), 87% of whom had laboratory-confirmed coronavirus infection. The cohort included 118 (11%) patients with single ventricle and/or Fontan physiology, 87 (8%) patients with cyanosis, and 73 (7%) patients with pulmonary hypertension. There were 24 COVID-related deaths (case/fatality: 2.3%; 95% confidence interval: 1.4% to 3.2%). Factors associated with death included male sex, diabetes, cyanosis, pulmonary hypertension, renal insufficiency, and previous hospital admission for heart failure. Worse physiological stage was associated with mortality (p = 0.001), whereas anatomic complexity or defect group were not.ConclusionsCOVID-19 mortality in adults with CHD is commensurate with the general population. The most vulnerable patients are those with worse physiological stage, such as cyanosis and pulmonary hypertension, whereas anatomic complexity does not appear to predict infection severity. 相似文献
16.
17.
18.
19.
Risk factors for transfer from Respiratory Intermediate Care Unit to Intensive Care Unit in COVID-19
《Respiratory investigation》2021,59(5):602-607
BackgroundPatients hospitalized for COVID-19-related pneumonia often need several degrees of ventilatory support, which are performed between Respiratory Intermediate Care Units (RICUs) and Intensive Care Units (ICUs), and which depend on the severity of acute respiratory distress syndrome. There is no firm consensus on transfer predictors from the RICU to the ICU.MethodsIn this retrospective observational single center study, we evaluated 96 COVID-19 patients referred to the RICU for acute respiratory failure (ARF) according to their transferal to the ICU or their stay at the RICU. We compared demographic data, baseline laboratory profile, and final clinical outcomes to identify early risk factors for transfer.ResultsThe best predictors for transfer to the ICU were elevated C-reactive protein and lymphopenia. The mortality rate was lower in the RICU than in the ICU, where transferred patients who died were mostly younger men and with less comorbidities than those in the RICU.ConclusionsFew inflammatory markers can predict the need for transfer from the RICU to the ICU. Due to the ongoing COVID-19 pandemic, we urge better clinical stratification by early and meaningful profiles in patients admitted to the RICU who are at risk of transferal to the ICU. 相似文献