Treatment outcome in endodontics: the Toronto study--phases 3 and 4: orthograde retreatment

Outcome 4-6 years after retreatment was assessed for Phases 3 and 4 of the Toronto Study. Of 477 teeth retreated, 333 were lost to follow-up, 18 were extracted, and 126 (41% recall, excluding 124 discontinuers) were examined for outcome of healed (periapical index score, < or = 2; no signs or symptoms) or diseased. When pooled with Phases 1 and 2, 187 of 229 teeth (82%) were healed. Logistic regression identified significant (P < or = .05) preoperative outcome predictors: root filling quality (odds ratio [OR], 4.18; confidence interval [CI], 1.72-10.12; healed: inadequate, 88%; adequate, 66%), perforation (OR, 4.01; CI, 1.28-12.62; healed: absent, 87%; present, 56%), and radiolucency (OR, 3.33; CI, 1.19-9.36; healed: absent, 93%; present, 80%). In teeth with radiolucency, outcome predictors were number of treatment sessions (OR, 12.08; CI, 1.84-infinity; healed: one, 100%; > or = 2, 77%) and previous root filling quality (OR, 7.68; CI, 2.36-26.89; healed: inadequate, 86%; adequate, 50%). Outcome was better in teeth with inadequate previous root filling, without perforation and radiolucency. Suggested significance of number of treatment sessions in teeth with radiolucency requires validation from randomized controlled trials.     

Treatment outcome in endodontics-The Toronto Study. Phases I and II: apical surgery

This study prospectively assessed the 4 to 8 yr outcome of apical surgery performed by graduate students in phases I and II of the Toronto Study. The study cohort included 155 teeth in 138 patients. Outcome was assessed by a blinded and calibrated examiner. Clinical and radiographic measures were used for a dichotomous outcome: healed (no signs and symptoms, Periapical Index score /= 3). The recall rate was 85% and the overall healed rate 74%. Healed rate was significantly higher for teeth with small (相似文献   

Treatment outcome in endodontics: the Toronto Study. Phase 1: initial treatment

This study assessed the 4- to 6-yr outcome of initial endodontic treatment during Phase 1 of the "Toronto Study" project. A total of 450 teeth were treated, alternating the "Schilder" technique and step-back with lateral condensation, and examined clinically and radiographically by an independent examiner. Apical periodontitis was recorded as absent (periapical index < 3) or present (periapical index > or = 3) and outcome dichotomized as "healed" (no apical periodontitis, no signs or symptoms) or "disease." Univariate, bivariate, and multivariate analyses were performed (p = 0.05) on 120 examined teeth. The "healed" rate (81% overall) was significantly higher for teeth treated without apical periodontitis (92%) than with apical periodontitis (74%). Several other factors were associated with healing rate differential of 10% or higher, but no statistical significance. This study confirmed apical periodontitis as the main prognostic factor in initial endodontic treatment. Continuation of the project will allow assessment of other prognostic factors with better power.     

Treatment outcome in endodontics: the Toronto Study. Phase III: initial treatment

The 4- to 6-year outcome of initial endodontic treatment was assessed for phase III (1998-1999) of the Toronto Study. Of the 532 teeth treated, 248 were from discontinuers (excluded), 142 from dropouts, 10 extracted, and 132 (50% recall) examined for outcome: healed (no apical periodontitis [AP], signs, symptoms) or diseased. Phase III was analyzed alone and combined with phases I, II (n = 373 teeth). Logistic regression performed on the combined phases I-III sample identified significant (p < or = 0.05) outcome predictors: preoperative AP (OR = 3.5; CI 1.7-7.2; healed: absent, 93%; present, 80%), number of roots (OR = 2.2; CI 1.0-4.7; healed: 1 - 92%; > or =2 - 83%), and intraoperative complications (OR = 2.2; CI 1.1-4.5; healed: absent, 88%; present, 76%). Treatment technique (OR = 2.8; CI 1.3-6.1; healed: Schilder, 89%; alternative, 73%) was suggested as an outcome predictor in teeth with AP, requiring confirmation from randomized controlled trials.     

Treatment outcome in endodontics: the Toronto study--phase 4: initial treatment

Outcome 4-6 years after initial treatment was assessed for Phase 4 (2000-2001) of the Toronto Study. Of 582 teeth treated, 430 were lost to follow-up (99 discontinuers, 331 dropouts), 15 were extracted, and 137 (32% recall minus 15 extracted teeth) were examined for outcome: healed (no apical periodontitis, signs, symptoms) or diseased. When pooled with Phases 1-3, 439 of 510 teeth (86%) were healed. Logistic regression identified 2 significant (P < or = .05) preoperative outcome predictors: radiolucency (odds ratio [OR], 2.86; confidence interval [CI], 1.56-5.24; healed: absent, 93%; present, 82%) and number of roots (OR, 2.53; CI, 1.25-5.13; healed: single, 93%; multiple, 84%). In teeth with radiolucency, intraoperative complications (OR, 2.27; CI, 1.05-4.89; healed: absent, 84%; present, 69%) and root-filling technique (OR, 1.89; CI, 1.01-3.53; healed: lateral, 77%; vertical, 87%) were additional outcome predictors. A better outcome was suggested for teeth without radiolucency, with single roots, and without mid-treatment complications. The predictive value of root-filling technique in teeth with radiolucency requires validation from randomized controlled trials.     

Treatment outcome in endodontics-the Toronto Study. Phase II: initial treatment

The 4- to 6-yr outcome of initial (first-time) endodontic treatment was assessed for Phase II of the "Toronto Study." In total, 442 teeth were treated by using flared preparation and vertical compaction of warm gutta-percha or step-back preparation and lateral compaction. With 126 teeth excluded (discontinuers: deceased and relocated patients), 163 dropouts, and 31 extracted, 122 (48% recall) were examined for outcome: "healed" (no apical periodontitis [AP], signs, symptoms) or "diseased" (AP, signs, or symptoms). Phase II was analyzed separately and combined with Phase I (n = 242), using Chi-square and Fisher's exact tests (p < or = 0.05). The healed rate (combined sample, 85%) differed significantly for preoperative AP (absent, 93%; present, 79%), treatment technique (flared preparation and vertical compaction, 90%; step-back preparation and lateral compaction, 80%), gender (females, 90%; males, 79%), number of roots (1-92%; > or = 2-81%), and root-filling length (adequate, 87%; inadequate, 77%). Logistic regression revealed increased risk of disease for preoperative AP (odds ratio = 3.3) and technique (odds ratio = 2.3). This study confirmed AP and highlighted treatment technique as the main predictors of outcome in initial treatment.     

Flare-ups in endodontics: II. Therapeutic measures. 1985

Various treatment regimens for the relief of pain during endodontic therapy, including relief of occlusion, pre-medication, establishment of drainage, and intracanal and systemic medications are presented. In addition, the rationale for the use of placebos is discussed.     

Flare-ups in endodontics: I. Etiological factors. 1985

A number of hypothetical mechanisms which may be responsible for pain and swelling before and during endodontic therapy are presented. These mechanisms may be interrelated.     

Root canal retreatment: I. Case assessment and treatment planning

Root canal retreatment is often the preferred method of treating a tooth in which root canal treatment has failed. Part one of this two-part article discusses reasons for failure of root canal treatment, case assessment and treatment planning. Part two describes some of the practical techniques that are available to the practitioner and the rationale for root canal retreatment.     

Ultrasonics in endodontics. Light microscope study

The purpose of this study was to study the efficacy of an endodontic cleansing procedure to remove the pulp and the dentin from the root canal system with a new endodontic instrument proposed by J.M. Laurichesse, the Shaper.     

Orthograde retreatment failure with extruded MTA apical plug in a large periradicular lesion followed by surgical intervention: case report

Absence of periapical healing after orthograde retreatment using an apical plug with mineral trioxide aggregate (MTA) can require surgical intervention. A patient with a root-filled maxillary central incisor with chronic apical periodontitis and sinus tract was referred for endodontic retreatment. Excessive apical enlargement was verified, indicating an MTA apical plug placement; however, an unintentional extrusion of MTA occurred during this step. The root canal was filled with gutta-percha and sealer, and periodic recalls were scheduled. The sinus tract was observed after six months and the lesion remained unaltered, although the extruded MTA had resorbed; therefore, an apicoectomy and retrograde root-end filling with MTA were performed. Absence of sinus tract, normal clinical aspect, and complete repair of the lesion were observed at the two-year follow-up.