膀胱癌的CT分期与病理对照

目的 分析膀胱癌的CT表现，并与手术病理对照，提高膀胱癌的术前分期诊断水平。方法分析13例膀胱癌的CT表现及术前分期，并与手术病理结果对照。结果膀胱癌主要表现为膀胱壁局限性或弥漫性增厚，形成菜花样肿物向腔内突出，可向壁外生长侵犯盆腔组织器官及淋巴结转移，膀胱周围脂肪间隙模糊。膀胱癌的术前CT分期正确率为69．3％。结论螺旋CT扫描能显示膀胱癌的CT特征及向膀胱壁内、外生长情况，对术前分期有意义。     

膀胱平滑肌瘤的MRI诊断及鉴别诊断

目的 探讨膀胱平滑肌瘤的MRI表现及鉴别诊断.方法 回顾性分析8例经手术病理证实为膀胱平滑肌瘤的临床资料、病理及MRI资料.结果 本组病例4例位于前壁,3例位于后壁,1例位于右侧壁;6例为黏膜下型(75.0%)、1例为壁间型(12.5%)、1例为浆膜下型(12.5%);8例T1WI均呈等信号,T2WI呈等/稍高信号,其中6例T2WI信号欠均匀,内见条状、斑片状高信号,压脂呈等信号,与盆壁肌肉信号基本一致,增强以轻中度强化为主,邻近膀胱壁及周围组织结构均无受侵.结论 膀胱平滑肌瘤的MRI表现有一定的特征性.     

Idiopathic bladder rupture

Deaths due to hemoperitoneum are not rare and can result from a variety of underlying pathologic processes, including natural disease as well as trauma. Whenever hemoperitoneum is identified at autopsy, it is incumbent upon the pathologist to identify the source of the hemorrhage. The authors present a case of probable traumatic rupture of the urinary bladder that resulted in lethal intra-abdominal hemorrhage, occurring in a young man who was found dead the morning after drinking heavily.     

Carcinosarcoma of the urinary bladder: dynamic contrast-enhanced MR imaging with clinical and pathologic correlation

OBJECTIVE: This article describes the MR imaging features of carcinosarcoma of the urinary bladder with clinical presentation and pathologic correlation in three adults. CONCLUSION: Carcinosarcoma of the urinary bladder is a rare and aggressive tumor that has a clinical presentation similar to that of transitional cell carcinoma of the bladder. Dynamic gadolinium-enhanced MR imaging features are discussed.     

Inflammatory pseudotumor of the bladder: MR findings.

We report a case of inflammatory pseudotumor of the bladder in a 29-year-old woman with gross hematuria that was considered as embryonal rhabdomyosarcoma on biopsy specimens. MRI demonstrated a polypoid tumor covered by clot, which disrupted the low intensity of the bladder wall. The lesion exhibited an intermediate signal on T1-weighted images and prominent high intensity on T2-weighted images and was markedly enhanced. A pathologic study revealed a tumor of myxoid stroma invading into the deep muscular layer of the bladder wall.     

MR imaging of urinary bladder neoplasms

The diagnostic potential of magnetic resonance (MR) imaging at 1.5 T for assessment and staging of urinary bladder tumors was investigated in 10 patients with malignant urinary bladder tumors. All patients underwent complete pathologic staging. The appearance of the urinary bladder tumors and the ability to stage them by means of MR imaging was evaluated morphologically and compared with results obtained with pathologic examination. Magnetic resonance imaging permitted tumor localization in all patients. In nine patients the tumor stage was accurately determined by MR imaging. The smallest tumor detected by MR imaging was 1.5 cm. Both transverse and sagittal imaging planes were found to be essential for accurate assessment of tumor extension. Signal intensity data obtained from both dual and multi spin echo sequences showed that tumor display and depth of infiltration was best seen with a repetition time (TR) of 2,000 ms and an echo time (TE) of 90 ms. Accurate evaluation of perivesical tumor infiltration required a sequence with a TR 800 ms and a TE 30 ms. Data presented here further support the role of MR in staging urinary bladder neoplasms.     

Absence of urine production due to renal failure enables clear visualization of primary urinary bladder carcinoma on 18F-FDG PET/CT

An 81-year-old man affected by renal failure, underwent 18F-FDG PET/CT for detecting primary lesion because of multiple lung nodules consistent with secondary lesions revealed by computed tomography without contrast. PET study documented high pathologic uptake at anterior and upper wall of urinary bladder, and a primary urinary bladder cancer was suspected. Biopsy confirmed the presence of a high-grade transitional cell carcinoma.     

Adenocarcinoma of the urachus: CT features

The CT findings of adenocarcinoma of the urachus in three patients were reviewed and correlated with pathologic features. The tumor was composed of two parts: supravesical and intravesical. The supravesical portion showed a cystic appearance with a capsule in the space of Retzius. The intravesical portions invading the dome of the bladder were polypoid and unencapsulated. These findings were consistent with pathologic findings in all three patients.     

Virtual cystoscopy of bladder neoplasms. Preliminary experience]

PURPOSE: We investigated the comparative sensitivity of virtual and conventional cystoscopy in patients with urinary bladder cancer. MATERIAL AND METHODS: Twelve patients (8 men and 4 women; mean age: 61 years, range: 49-73) with findings of bladder cancer at conventional cystoscopy were submitted to volumetric spiral CT of the urinary bladder. Before the examination, the urinary bladder was distended with 180-200 mL of air. CT findings were then sent to an independent workstation to generate interactive intraluminal views of the bladder. The findings of virtual cystoscopy were compared with those of conventional cystoscopy in 11 patients and with the findings of transurethral resection after urethrotomy in one patient. All lesions had pathologic confirmation. RESULTS: Eighteen (90%) of 20 masses detected on conventional cystoscopy were visualized with virtual cystoscopy. The latter allowed readers to identify 13 of 13 masses (100%) > 1 cm and only 5 of 7 (71%) < 1 cm; three 4-mm masses were missed. Although only a subjective evaluation of lesion size was possible on conventional cystoscopy, there seemed to be good agreement on mass size and site with both techniques. DISCUSSION: Cystoscopy plays a key role in the diagnosis of urinary bladder carcinoma. However cystoscopy is invasive, has a limited field of view and lacks an objective scale; moreover, it is not indicated in patients with severe urethral strictures or active vesical bleeding. In our study, virtual cystoscopy depicted all the masses > 1 cm, and a lesion in a diverticulum with a small opening. Virtual cystoscopy was also very useful in a patient with urethral stricture (who could no be submitted to conventional cystoscopy) where it showed the lesion before transurethral resection after urethrotomy. The virtual technique could also be complementary to conventional cystoscopy in evaluation of bladder base and anterior bladder neck, as well as for postchemotherapy follow-up. Unfortunately virtual cystoscopy does not allow biopsy of suspicious lesions.     

Nongynecologic bladder and perivesical ultrasound

Ultrasound is effective in evaluating pathologic entities in and around the urinary bladder. Abnormalities may be classified into 2 groups: lesions primarily affecting the bladder, including the bladder wall; and perivesical lesions, which secondarily affect the urinary tract. Intrinsic bladder diseases include inflammatory lesions, stones, and tumors, both primary and metastatic. Extrinsic perivesical abnormalities include lesions of the prostate, seminal vesicles, urethra, rectum, and perivesical soft tissues. Since the bladder is routinely visualized on pelvic ultrasonography, awareness and recognition of the ultrasonic appearance of disease in and around the urinary bladder can lead to more accurate diagnosis and detection of unsuspected disease.     

Inflammatory pseudosarcoma (pseudotumor) of the bladder

Inflammatory pseudosarcoma of the bladder is a rare benign entity that cannot be differentiated from malignant tumor at radiologic examination alone. Only pathologic examination can enable a definitive diagnosis. The authors report two cases of these benign tumors in patients with no history of bladder disease or trauma; the tumors were large, demonstrated invasion into local tissues, and recurred in one case after incomplete transurethral resection.     

Misleading findings on indium-111 leukocyte images

In-111 leukocyte imaging usually yields images which are interpreted easily. Five potentially misleading cases were noted, however, of over 200 scans performed over a four-year period. These included two cases of bladder visualization without bladder inflammation and three cases of abdominal activity without intra-abdominal abscess or inflammatory bowel disease. Migration of leukocytes from other true pathologic sites and technical factors were responsible for the activity seen. Knowledge of all aspects of the patient's clinical status, including other diagnostic modalities performed, was critical in arriving at the correct diagnosis.     

Primary bladder carcinoma: evaluation with MR imaging

Magnetic resonance (MR) imaging was performed in 23 patients (25 tumors) with proved bladder neoplasms. MR studies were retrospectively evaluated and compared with computed tomographic (CT) and pathologic findings. Bladder neoplasms, having a signal intensity intermediate between those of urine and perivesical fat, were best seen on T1-weighted and proton-density images. MR imaging was as accurate as technically well-performed CT studies in detecting extravesical tumor extension. MR could additionally be used to assess the integrity of the bladder wall. On T2-weighted images the normal bladder wall appeared as a thin, linear, low-intensity structure. The disruption of this low-intensity line was indicative of deep muscle invasion, whereas preservation of this low intensity line implied a more localized lesion. Although chemical shift artifacts might cause apparent disruption of the bladder wall, knowledge of this artifact coupled with additional imaging along different planes helps avoid misinterpretation of this artifact as deep muscle invasion.     

Magnetic resonance imaging of the pelvis: prostate and urinary bladder

Magnetic resonance imaging has opened up a new horizon in the evaluation of the male pelvis. Its direct multiplanar imaging and display of the unique tissue contrast allows for the demonstration of prostate anatomy. Prostatic disease, even when confined to the gland, is easily depicted. However, one cannot distinguish benign from malignant processes. In a patient with a known prostatic neoplasm, magnetic resonance is useful as a staging modality. Accuracy in the staging of prostatic malignancies by MRI surpasses that of ultrasound or CT. In the evaluation of the urinary bladder, the greatest advantage of magnetic resonance is its ability to differentiate between a normal bladder, and other pathologic conditions affecting the bladder, including inflammatory, congestive and neoplastic processes. In the evaluation of bladder carcinoma, magnetic resonance is useful as a staging modality. Clinical application of magnetic resonance is just beginning and therefore, the full potential of the modality has yet to be explored.     

Magnetic resonance imaging of the pelvis: Prostate and urinary bladder

Magnetic resonance imaging has opened up a new horizon in the evaluation of the male pelvis. Its direct multiplanar imaging and display of the unique tissue contrast allows for the demonstration of prostate anatomy. Prostatic disease, even when confined to the gland, is easily depicted. However, one cannot distinguish benign from malignant processes. In a patient with a known prostatic neoplasm, magnetic resonance is useful as a staging modality. Accuracy in the staging of prostatic malignancies by MRI surpasses that of ultrasound or CT. In the evaluation of the urinary bladder, the greatest advantage of magnetic resonance is its ability to differentiate between a normal bladder, and other pathologic conditions affecting the bladder, including inflammatory, congestive and neoplastic processes. In the evaluation of bladder carcinoma, magnetic resonance is useful as a staging modality. Clinical application of magnetic resonance is just beginning and therefore, the full potential of the modality has yet to be explored.     

Significance of absent or faint kidney sign on bone scan.

Seven men, six suffering from widespread bone metastases of prostatic origin and one with urinary bladder carcinoma, demonstrated minimal or no discernible radioactivity in the kidneys and urinary bladder at the time of bone scanning using 99mTc-stannous polyphosphate. The mechanism behind this scan finding is thought to be rapid and enhanced uptake of the radiopharmaceutical by pathologic bone. The significance of the faint or absent kidney sign in bone scanning, particularly in cases where abnormally homogeneous and symmetric radioactivity exists, is discussed.     

Bladder cancer: staging with CT and MR imaging

Magnetic resonance (MR) imaging and computed tomography (CT) were compared in 30 patients with histologically proved bladder cancer. MR imaging was accurate in depicting the presence or absence of extravesical spread in 22 patients (accuracy, 73%; sensitivity, 82%; specificity, 62%), and CT was accurate in 24 patients (accuracy, 80%; sensitivity, 94%; specificity, 62%). The MR examinations of two patients were of undiagnostic quality and therefore considered to be technical failures. Each technique resulted in five false-positive and one false-negative examination for the diagnosis of extravesical tumor spread. In 28 patients the integrity of the bladder wall was assessed with MR imaging. In 22 patients the bladder wall was disrupted, and 18 of these patients had deep muscle invasion. In six patients the bladder wall was intact, and none of these patients had evidence of deep muscle invasion at pathologic examination. In this study MR imaging was slightly inferior to CT in the delineation of invasive tumors beyond the bladder wall. However, if one excludes from analysis the two patients with undiagnostic studies, there is no significant difference in accuracy between the two techniques.     

MR imaging of bladder neoplasms: Correlation with pathologic staging

This retrospective study describes the accuracy of magnetic resonance (MR) imaging in determination of local disease extent in 34 examinations performed for evaluation of primary or recurrent bladder carcinoma. The 34 examinations were carried out in 29 patients (17 men, 12 women, aged 34-89 years). All studies were followed within 30 days by surgical and pathologic evaluation. Images were interpreted by two radiologists unaware of clinical or pathologic findings. MR imaging staging conformed to the TNM system of the International Union Against Cancer (IUAC). Pathologic evaluation showed bladder neoplasms in all cases; three patients' pathologic specimens contained two or more histologic types of tumors. MR imaging staging of the depth of tumor invasion was correct in 85% of examinations. Sensitivity of MR imaging for detection of deep muscle invasion was 97%, specificity 83%, and accuracy 94%. Sensitivity of MR imaging for detection of extravesical tumor extension was 95%, specificity 100%, and accuracy 97%. Sensitivity for detection of pelvic lymph node metastases was 50%, specificity 100%, and accuracy 82%. Our population included many patients with locally advanced disease. This pattern reflects standards of clinical practice by which superficial lesions are staged and resected endoscopically, and deeply invasive tumors are imaged prior to radical surgery.     

Urachal carcinoma: CT findings

The computed tomographic (CT) appearance of urachal carcinoma in ten patients was studied and compared with the pathologic findings. Magnetic resonance images were available in one case. All tumors were mucinous adenocarcinomas; four were solid, three were cystic, and three were mixed. The tumor had a characteristic location along the expected midline course of the urachus directly behind the anterior abdominal wall. The main tumor mass was supravesical in eight patients. Seven tumors contained calcification. CT correctly depicted bladder wall involvement and supravesical extent of tumor in all cases. CT provided incorrect information about invasion of the perivesical fat in three patients and about bladder mucosal invasion in two patients.     

Solitary fibrous tumor of the male pelvis: findings at CT with histopathologic correlation

We present CT imaging findings with pathologic correlation in a rare case of a solitary fibrous tumor arising in the pelvis in a 34-year-old man. This tumor presented as a hypervascular heterogeneously enhancing deep pelvic mass at CT. Although CT initially suggested the prostate as the site of origin for this tumor, no prostate involvement was found at surgery; CT accurately excluded bladder and rectal involvement.