Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes

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Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy

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Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection

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BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

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Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

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An in vitro platform supports generation of human innate lymphoid cells from CD34+ hematopoietic progenitors that recapitulate ex vivo identity

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Clonal multi-omics reveals Bcor as a negative regulator of emergency dendritic cell development

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A non-classical monocyte-derived macrophage subset provides a splenic replication niche for intracellular Salmonella

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Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development

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Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

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Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

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Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease

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Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

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Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges

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Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation

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Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions

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Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid

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Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments

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Newly recruited intraepithelial Ly6A+CCR9+CD4+ T cells protect against enteric viral infection

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The Emergence and Functional Fitness of Memory CD4+ T Cells Require the Transcription Factor Thpok

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