The 100 most influential papers about cataract surgery: a bibliometric analysis

AIM: To identify the 100 most cited papers in cataract surgery, we performed a comprehensive bibliometric analysis basing on the literature search on the Thomson Reuters Web of Knowledge. METHODS: The number of citations, including the total citations, latest 5y citations and average citation number per year (ACY), authorship, year of publication, major topics, journal of publication, country and institution of origin of each paper were recorded and then analyzed. Pearson’s correlation analysis was conducted to evaluate the correlation between the published year and the number of citations. The correlation between journal’s impact factor (IF) and number of citations was assessed as well. RESULTS: The most cited paper was the classic paper done by the European Society of Cataract & Refractive Surgeons (ESCRS) group. This paper focused on the topic of endophthalmitis. Not only the most cited papers originated from the USA, but also some American institutions like Johns Hopkins University, Harvard Medical School, etc. had the most citations. Pearson’s correlation analysis indicated that the latest 5y citations and ACY were significantly related with the published year (5y citations: r=0.615, P<0.001; ACY: r=0.657, P<0.001), whereas no association between the total number of citations and published year was found (r=0.045). Moreover, the IFs of journals were found to have no significant effect on the number of total citations. CONCLUSION: To our knowledge, this is the first study on the most influential papers in cataract surgery after a comprehensive research of relevant literatures. The present work may provide us concise information concerning the development history of cataract surgery over the past 66y.     

[In Press] The 100 most influential papers about cataract surgery: a bibliometric analysis

AIM: To identify the 100 most cited papers in cataract surgery, we performed a comprehensive bibliometric analysis basing on the literature search on the Thomson Reuters Web of Knowledge. METHODS: The number of citations, including the total citations, latest 5y citations and average citation number per year (ACY), authorship, year of publication, major topics, journal of publication, country and institution of origin of each paper were recorded and then analyzed. Pearson''s correlation analysis was conducted to evaluate the correlation between the published year and the number of citations. The correlation between journal''s impact factor and number of citations was assessed as well. RESULTS: The most cited paper was the classic paper done by the European Society of Cataract & Refractive Surgeons (ESCRS) group. This paper focused on the topic of endophthalmitis. Not only the most cited papers originated from the USA, but also some American institutions like Johns Hopkins University, Harvard Medical School etc. had the most citations. Pearson’s correlation analysis indicated that the latest 5y citations and ACY were significantly related with the published year (5y citations: r=0.615, P<0.001; ACY: r=0.657, P<0.001), whereas no association between the total number of citations and published year was found (r=0.045). Moreover, the impact factors (IF) of journals were found to have no significant effect on the number of total citations. CONCLUSION: To our knowledge, this is the first study on the most influential papers in cataract surgery after a comprehensive research of relevant literatures. The present work may provide us concise information concerning the development history of cataract surgery over the past 66y.     

Trends in research related to high myopia from 2010 to 2019: a bibliometric and knowledge mapping analysis

AIM:To evaluate the global trends in and explore hotspots of high myopia(HM)research.METHODS:This bibliometric analysis was used to reveal the publication trends in HM research field based on the Web of Science Core Collection(WoSCC).VOSviewer version 1.6.13 software was used to analyze the data and construct a knowledge map including the yearly publication number,journals,countries,international collaborations,authors,research hotspots,and intellectual base in HM.RESULTS:The search engine found 3544 peer-reviewed publications on HM between 2010 and 2019,and the yearly research output substantially elevated over the past decade.China is the top publishing country,and Sun Yatsen University was the most active academic institution.Jonas JB is the top publishing scientist,and Investigative Ophthalmology and Visual Science(IOVS)was the most productive journal.The highest cited references mainly focused on epidemiology and management.The keywords formed 6 clusters:1)refractive surgery;2)etiology and clinical characteristics;3)the mechanism of eye growth;4)management for myopic maculopathy;5)vitrectomy surgical treatment;6)myopia-associated glaucoma-like optic neuropathy.CONCLUSION:The evaluation of development trends based on the data extracted from WoSCC can provide valuable information and guidance for ophthalmologists and public health researchers to improve management procedures in HM field.     

Citation analysis of the most influential authors and ophthalmology journals in the field of cataract and corneal refractive surgery 2000-2004

Purpose: To identify the most published authors on the topics of ‘cataract’ and ‘LASIK’, the journals in which they publish, and the citation patterns of the most‐cited articles by these authors over a 5‐year publication period. Methods: Science Citation Index Expanded (SCI) was used to identify the 30 most‐published authors in ‘cataract’ and ‘laser in situ keratomileusis’ (LASIK) (2000–2004 inclusive). SCI was subsequently used to analyse the recorded articles for each author in terms of source journal, the most commonly cited articles and citation source. Results: Of the 30 most‐published authors in the fields of cataract and LASIK, the USA was the most well‐represented source country, accounting for 33%; 20% were from Australia, and 17% from Austria. Germany and Japan each contributed 7%. Eighty per cent of the publications produced by these 30 authors (2000–2004) were in 10 journals, of which the Journal of Cataract and Refractive Surgery (JCRS) published more than one‐third. Of the three most‐cited articles for each author, the greatest number were published in JCRS (35.6%). The citation count of the articles had a weak correlation to the journal impact factor of the source journal; however, the self‐citation rate of these articles did not. Conclusions: The USA and Australia together were the source of more than half of the most‐published authors on cataract and LASIK and the majority of articles published by the 30 most prolific authors were published in only 10 journals. The impact factors of the publication journals preferred by these authors are influenced by the article citation counts, not vice versa.     

Top 100 cited articles in ophthalmic epidemiology between 2006 and 2016

AIM: To identify the most-cited articles in ophthalmic epidemiology over the last decade. METHODS: We performed a cited reference search on articles that were included in the ISI Web of Science database using the terms “Epidemi*” AND “ophthalm*” AND “population*” during year 2006 to 2016. TOP 100 most cited articles (T100) in ophthalmic epidemiology were short listed and analysed using bibliometrics. RESULTS: These top 100 articles in ophthalmic epidemiology were cited between 61 to 333 times. Of these T100 articles, 36% originated from United States, and 34% were published in the Ophthalmology journal. The three major topics identified were age-related macular degeneration (AMD, n=23), glaucoma (n=16) and visual impairment (n=12). The top-cited article was a study on outdoor activities and its association with the prevalence of myopia in school-aged children, published in 2008. CONCLUSION: This bibliometric analysis provides useful insights into the current development in ophthalmic epidemiology in the past decade and can help recognizing the quality of the researches, discoveries, and trends steering ophthalmic epidemiology.     

近视眼手术矫治的临床进展

本文就矫治近视的准分子激光角膜屈光手术、晶状体性屈光手术及如何制定个性化屈光手术方案等临床进展作一综述。     

Bibliometric analysis of hotspots and trends of global myopia research

AIM: To gain insights into the global research hotspots and trends of myopia. METHODS: Articles were downloaded from January 1, 2013 to December 31, 2022 from the Science Core Database website and were mainly statistically analyzed by bibliometrics software. RESULTS: A total of 444 institutions in 87 countries published 4124 articles. Between 2013 and 2022, China had the highest number of publications (n=1865) and the highest H-index (61). Sun Yat-sen University had the highest number of publications (n=229) and the highest H-index (33). Ophthalmology is the main category in related journals. Citations from 2020 to 2022 highlight keywords of options and reference, child health (pediatrics), myopic traction mechanism, public health, and machine learning, which represent research frontiers. CONCLUSION: Myopia has become a hot research field. China and Chinese institutions have the strongest academic influence in the field from 2013 to 2022. The main driver of myopic research is still medical or ophthalmologists. This study highlights the importance of public health in addressing the global rise in myopia, especially its impact on children’s health. At present, a unified theoretical system is still needed. Accurate surgical and therapeutic solutions must be proposed for people with different characteristics to manage and intervene refractive errors. In addition, the benefits of artificial intelligence (AI) models are also reflected in disease monitoring and prediction.     

眼内屈光手术治疗超高度近视的现状

超高度近视的具体病因尚不清楚,用框架眼镜矫正具有视野狭小、物像畸变、镜片厚重配戴不便等缺点,准分子激光手术因角膜本身条件受限不能进行充分矫正。而近年来晶状体相关的屈光手术矫正超高度近视均获得了较满意的效果,我们就目前各类眼内晶状体相关的屈光手术的优缺点和治疗现状作一综述。     

近视眼LASIK术后立体图形的辨认时间

目的:观察近视眼准分子激光原位角膜磨镶术(excmier laser in situ keratomileusis,LASIK)后立体视功能的变化,从视觉最高形式的角度评价LASIK手术的疗效。方法:2006-08/2006-12间观察在我院行LASIK手术的4例中、高度近视患者,于术前,术后1wk,术后1mo检查远体视锐度(包括交叉视差和非交叉视差)及测量远立体视锐度最小辨别阈值的辨认时间。结果:所有观察病例术后裸眼视力均在0.8以上,远立体视锐度正常。术后1mo时中、高度近视患者的远立体视锐度最小辨别阈值的辨认时间较术前的缩短。结论:LASIK手术使双眼屈光状态变为正视,远立体视锐度恢复正常,远立体视锐度图片辨认时间缩短;双眼视力相等,调节性辐辏与调节相平衡,有利于形成双眼单视和立体感知。     

Bibliometric analysis of research relating to refractive cataract surgery over a 20-year period: from 2003 to 2022

AIM: To investigate the research trend on refractive cataract surgery, compare the contributions of different countries, institutions, journals, and authors in the past 20y, and explore its potential research hotspots.METHODS: All publications were extracted relating to refractive cataract surgery from 2003 to 2022 from Web of Science. Document types were limited to original articles and reviews, and the language was limited to English. Quantitatively and qualitatively of the publications were analyzed through Microsoft Excel and GraphPad Prism. VOSviewer and CiteSpace were used for bibliometric and visualized analysis.RESULTS: A total of 2090 publications were enrolled. The United States contributed the most publications (434, 20.8%), followed by China (345, 16.5%) and England (163, 7.80%). Publications from the United States were cited more frequently (9552 citations) with the highest H-index of 48. China ranked second in the total number of publications, the papers were not cited that frequently (3237 citations), and the H-index ranked sixth (H-index=29). Journal of Cataract and Refractive Surgery published the most papers (333, 15.9%), and the University of London had the highest number of publications (75, 3.59%). Dick HB from Germany published the most papers. Corneal astigmatism-related research, cataract surgery method-related research, postoperative visual-quality relate to research, and postoperative complications-relate research are the hotspots in this field. The most significant limitation was that the database was updated frequently and the latest publications were not included.CONCLUSION: The bibliometric analysis shows a brief summarization of the contribution of the authors, institutions, countries, and journals. Corneal astigmatism, cataract surgery method, postoperative visual-quality and postoperative complications related researches have become the emerging hotspots, which can give a direction in the future researches.     

影响近视眼角膜屈光力多因素分析

目的:探讨影响近视眼角膜屈光力的相关因素。方法:分别测量227例(452眼)近视及近视散光患者角膜地形图、角膜中央厚度、眼压、A超及屈光度,将所得结果进行统计学分析。结果:①不同程度屈光度,角膜顶点屈光力低度近视组与中、高、重度近视组比较有显著性差异(P <0.05),角膜中央3mm屈光力,低、中度近视组与重度近视组比较有显著性差异(P <0.05),角膜中央5mm屈光力低度近视眼组与重度近视组比较有显著性差异(P <0.01),角膜中央7mm屈光力各组之间比较无显著性差异(P >0.05);②角膜中央3,5,7mm的屈光力与年龄、前房深度呈正相关(年龄:r分别为:0.398,0.387,0.342,P =0.000;前房深度:r分别为:0.277,0.310,0.288,P =0.000);③角膜中央3,5,7mm的屈光力均与等效球镜屈光度、眼轴、晶状体厚度呈负相关(等效球镜屈光度:r分别为-0.80,-0.782,-0.710,P =0.000;眼轴:r分别为:-0.670,-0.668,-0.598,P =0.000;晶状体厚度r分别为-0.318,-0.282,-0.232,P值分别为0.000,0.000,0.001);④将角膜不同区域屈光力为应变量,分别建立多元线性回归方程:Y 3=77.571-1.432X 1-0.554X 2 0.964X 3 0.067X 4-1.205X 5;(F =101.356,P =0.000);Y 5=76.538-1.424X 1-0.538X 2 1.063X 3 0.067X 4-1.122X 5;(F =92.395,P =0.000);Y 7=72.563-1.     

中低度近视LASEK术后角膜地形图分析

目的　探讨中低度近视准分子激光上皮瓣下角膜磨镶术 (LASEK)后的角膜地形图变化。方法　中低度近视LASEK术 40例 (80眼 ) ,术前及术后 1、3、6月行角膜地形图检查 ,与综合验光结果进行相关分析。结果　LASEK术后 6月裸眼视力≥ 0 .6者占 10 0 .0 0 % ,其中≥ 1.0者占 97.5 0 %。 80眼术前角膜地形图表现最多者为对称领结形 ,依次为非对称领结形 ,圆形 ,椭圆形及不规则形。术后 6月检查时角膜地形图主要表现为圆形或椭圆形 (75 .0 0 % ) ,肾形 (2 1.2 5 % )及半环形 (3 .75 % )。LASEK术后 (SAI)、SimK等效值和SimK的差值较术前变化显著 (P <0 .0 5 ) ,SRI改变则不显著。结论　LASEK治疗中低度近视疗效佳。角膜地形图的定量分析对术后角膜表面球面性状的评价、手术设计的改进和疗效的预测具有重要意义。     

有晶状体眼屈光性人工晶状体Phakic 6植入术矫正高度近视

目的探讨有晶状体眼屈光性人工晶状体Phakic6植入术矫正高度近视的安全有效性。方法表面麻醉下对9例(18眼)高度近视(-12.00~-24.00D)患者行Phakic6植入术。手术前后检查术眼裸眼及矫正视力、眼压、Phakic6在眼内的位置、角膜内皮计数。结果经术后3~12月随访观察,术后所有术眼裸眼远、近视力均达到或高于术前最佳矫正视力;术眼眼压在正常范围;术眼角膜内皮计数均大于2500个·mm-2;除1例1眼出现了Phakic6前房内旋转,另1例1眼出现瞳孔轻度扩大并上移外,其余术眼Phakic6前房内位置稳定,与角膜及自身晶状体之间保留有安全距离,房角镜下未见人工晶状体袢压迫小梁网,无视网膜脱离及慢性色素膜炎反应。结论Phakic6眼内植入矫正高度近视效果显著,但远期效果及安全性还有待于进一步观察。     

国人近视屈光手术人群Q值的相关因素分析

目的探讨我国近视屈光手术人群的角膜前表面非球性参数（Q值）的分布及其相关因素。方法随机选择18～44岁行近视分子激光角膜屈光手术者120例（240眼）。按屈光度分为低、中、高度3组,各组均为40例（80眼）。应用AstraMax二三维角膜综合检查站行角膜地彤网检查,记录角膜曲率及Q值;并行综合验光、角膜中央厚度、眼轴长度及其他常规术前检查。分别将Q值与各参数进行统计学分析。结果总体Q值均数为-0．16±0．17,呈正态分布;Q〈0者206眼,占85．83％;Q值与性别、眼别间差异无统计学意义;Q值与屈光度之间存在线性相关关系（F=9．6665,P〈0．05）,高度近视组和低度、中度组问的差异有统计学意义（q=4．0037,P〈0．05;q=3．1218,P〈0．05）;低中度近视组问差异无统计学意义。Q值与角膜中央厚度、平均角膜曲率、眼轴长度呈无相关性。结论我国近视屈光手术人群的Q值呈正态分布,大部分人群角膜为长椭圆形（prolate）。Q值与屈光不正程度相关,而与性别、角膜中央厚度、平均角膜曲率、眼轴长度之间无相关性。     

近视眼患者选择准分子激光角膜屈光手术的影响因素

目的:探讨影响近视眼患者选择准分子激光角膜屈光手术的因素。方法:2007-06/2008-05近视患者734例进行问卷调查,内容包括患者人群特征、近视及矫正的情况、手术原因及对手术相关信息的了解情况、对医疗服务的满意程度等。采用Logistic回归分析影响近视眼患者选择准分子激光角膜屈光手术的相关因素。结果:在734例咨询者中,581例患者进行了手术,153例未手术。多因素非条件Logistic回归分析结果表明患者年龄、性别、教育水平、近视时间、近视程度、获得手术信息的途径、对手术了解程度、对手术期望程度、就医环境的好坏,手术医师技术的好坏,服务满意度等因素是影响近视眼患者是否选择准分子激光角膜屈光手术的主要因素。结论:影响近视眼患者选择准分子激光角膜屈光手术的因素较多。医务人员应该合理宣传准分子激光角膜屈光手术的安全性和疗效,改善患者的就医环境,提高服务满意率,使近视患者对手术疗效有合理的期望,正确选择手术。     

LASIK矫正近视术后5a疗效观察

目的　评价准分子激光原位角膜磨镶术矫正近视术后 5a的效果和安全性。方法　对接受准分子激光原位角膜磨镶术矫正近视术后 5a的患者 4 9例 89眼进行裸眼视力、屈光度和最佳矫正视力的随访 ,被随访眼按屈光度数分为 4组 :≤ - 6 .0 0D、- 6 .2 5～ - 10 .0 0D、- 10 .2 5～ - 15 .0 0D、≥- 15 .2 5D。结果　术后 5a各组的裸眼视力≥ 1.0分别为10 0 %、83%、4 9%和 4 % .与术后 6个月比较 ,术后 5a各组屈光度数回退≥ 1.0D分别为 0 %、17%、18%和 2 8% .最佳矫正视力≥ 1.0分别为 10 0 %、10 0 %、85 %和 5 6 % .术后最佳矫正视力不变或上升 1行分别为 86 %、79%、70 %和 2 0 % ,最佳矫正视力比术前上升 2行以上的分别为 14 %、13%、15 %和4 8% .结论　准分子激光原位角膜磨镶术治疗近视远期效果稳定 ,手术安全性好。     

眼内屈光手术对高度近视患者视功能的影响

目的探讨眼内屈光手术对高度近视患者视功能的影响。方法 160例(320眼)高度近视患者分别接受透明晶状体摘出术和有晶状体眼的人工晶状体植入术,分别检查患者术前、术后1个月的视力、立体视觉、屈光度,并进行对比分析。结果 160例患者术前平均裸眼视力为0.12±0.05,平均最佳矫正视力为0.81±0.13;术后平均裸眼视力为0.95±0.05,平均最佳矫正视力为1.24±0.28;与术前相比,术后裸眼视力与最佳矫正视力均有明显提高,差异均有统计学意义(均为P<0.05)。所有患者术后均获得远、近立体视,与术前相比,术后远、近立体视均有明显改善,差异均有显著统计学意义(均为P<0.01)。术后屈光度和屈光参差患者参差度均较术前明显减小,差异均有统计学意义(均为P<0.05)。结论眼内屈光手术可充分矫正屈光不正,减小双眼间的屈光差异,使高度近视患者在获得清晰视觉的同时,有效改善立体视觉。     

Factors affecting single-step transepithelial photorefractive keratectomy outcome in the treatment of mild, moderate, and high myopia: a cohort study

AIM: To investigate the effect of preoperative factors on visual acuity, higher-order aberrations (HOAs), and index of success for spherical change (S.IOS) after transepithelial photorefractive keratectomy (t-PRK) for treating different grades of myopia. METHODS: This was a retrospective one-armed cohort study where patients with high, moderate, or mild myopia treated with single-step t-PRK using Amaris 500 Hz excimer laser were evaluated for visual acuity, refractive status, corneal topography, HOAs, S.IOS, and mean efficiency and safety index before and 6mo after surgery. RESULTS: A total of 154 eyes of 77 patients with mild (n=59), moderate (n=83), and high (n=12) myopia were reviewed. The efficiency and safety indices for vision recovery by single-step t-PRK were 98% and 100%, respectively. The achieved spherical equivalent (SE) was within 1 diopter (D) in 151 (98%) eyes. The median of the S.IOS was 1.18 [interquartile range (IQR) 1.0, 1.4]. The change in S.IOS was significantly correlated with age (P=0.007), 6.5 mm ablation zone (Mann-Whitney U test, P<0.01), and mild and moderate grade of myopia (Kruskal–Wallis test, P<0.001). Trefoil aberration, spherical aberration, and aberration coefficient types of HOA increased significantly (Wilcoxon test, P<0.001) 6mo post-surgery. There was a significant correlation between spherical aberration and aberration coefficient HOAs by myopia grades (P<0.05). CONCLUSION: Single-step t-PRK has promising short-term outcomes for refractive corrections and vision improvement to treat all three grades of myopia.     

超声乳化透明晶状体联合人工晶状体植入治疗高度近视

目的:探讨超声乳化透明晶状体联合人工晶状体植入治疗高度近视的有效性和安全性.方法:对我院自2004/2006年25例43眼的高度近视患者施行透明晶状体超声乳化联合人工晶状体植入术.平均年龄48.6岁,术前患者裸眼视力0.01～0.25,屈光度数平均-13.75±0.26D,平均散光度数1.07±0.86D,矫正视力0.1～0.6,平均眼轴长度28.13±2.32mm.结果:所有患者裸眼视力均比术前提高,其中术后1d 4眼(9%)0.1～0.12者9眼(21%)0.15～0.4者30眼(70%)≥0.5;术后3mo 18例主导眼裸眼视力均≥0.5,40眼(93%)矫正视力≥0.5,其中3眼(7%)因后巩膜葡萄肿及黄斑病变矫正视力较差0.12～0.3;所有患者术中术后无严重并发症,术后屈光状态稳定,未见回退的现象.结论:超声乳化透明晶状体联合人工晶状体植入术可治疗其他屈光手术难以解决的高度近视,是这一部分患者获得正视的安全、有效、准确和稳定的可靠途径.     

后巩膜加固术后的眼内屈光手术治疗病理性近视的临床观察

目的:观察后巩膜加固术(posterior scleral reinforcement surgery,PSR)后眼内屈光手术治疗病理性近视的临床疗效。方法:对178例(323眼)病理性近视患者先行后巩膜加固术,1mo后再行眼内屈光手术,随访18mo。结果:最佳矫正视力(BCVA)PSR手术前后为4.65±0.38和4.72±0.33,差异有统计学意义(P<0.05),眼内屈光手术后1,12,18mo为4.80±0.30,4.86±0.29,4.82±0.31,与屈光手术前比较差异均有统计学意义(P<0.05);屈光度眼内屈光手术前及手术后1,12,18mo分别为-16.36±5.03D和-0.98±1.23D,-0.99±1.24D,-0.96±0.99D,术后各时期分别比较差异无统计学意义(P>0.05);眼轴PSR手术前后为29.92±2.68mm和29.80±2.58mm,差异无统计学意义(P>0.05),眼内屈光手术术后18mo眼轴为29.84±2.56mm,与术前比较差异无统计学意义(P>0.05);手术无严重并发症发生。结论:对于病理性近视患者,行后巩膜加固术后的眼内屈光手术进行屈光矫正,有效稳定,远期效果尚待进一步观察。