胃癌全胃切除“P”型空肠间置代胃术24例分析

中国图书分类号】Ｒ７３５２Ｒ６５６６１我院自１９８８年１月～１９９６年１月对２４例胃癌病人施行根治性全胃切除，“ｐ”型近端空肠间置代胃术，效果较好，报告如下。陆林，男，３６岁，大学本科，主治医师，江苏油田医院外科，２２５２６１江苏省扬州市邵伯镇建...     

胃癌全胃切除功能性间置空肠代胃术42例报告

目的:探讨功能性间置空肠代胃术在全胃切除术中的应用及效果,以减少并发症,提高患者生活质量.方法:对42例胃癌患者应用功能性间置空肠代胃术,并进行定期随访.结果:施此术式患者未发生食管空肠吻合口瘘、食管炎及无胃综合征等并发症,患者术后存活率高,精神、营养状况良好,恢复部分体力活动.结论:功能性间置空肠代胃术是值得推荐的全胃切除的消化道重建术.     

全胃切除-功能性间置空肠代胃术后护理

目的:探讨全胃切除-功能性间置空肠代胃新术式术后护理方法.方法:对42例行此术式的病人施行了个性化的护理和科学合理的营养支持与康复指导.结果:降低了术后并发症,提高患者生活质量.     

全胃切除P型空肠间置原位代胃术

目的 探讨全胃切除术P型空肠间置原位代胃术的效果。方法 对15例符合全胃切除的病人，施行了全胃切除P型空肠间置原位代胃术。结果 本组无手术死亡，无切口、腹腔感染及吻合口瘘。发生反流性食管炎，进油腻性食物后恶心各1例，对症治疗缓解。15例均于术后0.5,1,6个月行钡餐检查，P型胃充盈良好，钡剂全部排空时间3－4h。术后6个月和1年病人饮食量、体重分别恢复到术前的82.5%，98％和89％,98.5%。1，3，5年存活率分别为86.6%，60％和23％。结论 全胃切除P型空肠间置原位代胃术，符合解剖生理规律，并发症少，代胃效果较理想。     

根治性全胃切除空肠间置代胃术疗效分析

目的探讨根治性全胃切除空肠间置代胃术对胃癌患者营养状况及生存质量的影响。方法对35例胃癌患者行根治性全胃切除空肠间置代胃术治疗,回顾性分析患者的临床资料。结果本组均顺利完成手术,术后生存期限均在1年以上。除3例患者术后出现轻度腹部疼痛外,其余均无出现食物反流、胸骨后烧灼、吞咽困难、胆汁反流症及吻合口炎症等并发症。与术前相比,所有患者术后平均体质量显著增加。血红蛋白、总蛋白、白蛋白水平显著提高并恢复至正常水平,差异有统计学意义(P0.05)。患者治疗后生存质量(QOL)评分及各维度得分较治疗前显著提高,差异有统计学意义(P0.05)。结论对胃癌患者行全胃切除手术后实施空肠间置手术重建消化道,可保留患者胃肠道生理功能,改善术后营养状况,提高术后生存质量。该手术操作简单、吻合口瘘发生率低,手术安全可靠,值得临床推广应用。     

空肠间置代胃术的前瞻性随机对照研究

目的:探讨空肠原位间置代胃术在全胃切除术后消化道重建中的价值。方法:以12例健康人为对照,将140例胃癌全胃切除术病人按消化道重建术式不同分为4组。A组:食管空肠Roux鄄y吻合术;B组:食管空肠“P”襻加Roux鄄y吻合术;C组:食管空肠Hunt鄄Lawrence吻合术;D组:食管空肠原位间置代胃术。比较4组病人术后的生活质量、预后营养指数(PNI)、体重、血液营养学指标、胃肠激素水平及免疫功能,并以此判断各术式之优劣。结果:D组病人的PNI、体重和血液营养学指标(血清铁、转铁蛋白、Hb)均优于A、B、C组(P<0.05);D组餐后30min的胆囊收缩素(CCK)水平及自然杀伤细胞(NK)、CD4、CD8及CD4/CD8值与对照组相似,而均优于A、B、C组(P<0.05)。差异均具显著性。结论:空肠原位间置代胃术是一较合理的重建术式。空肠“P”形构造不仅具有代胃之功能,且可降低十二指肠液逆蠕动冲力,防止反流性食管炎的发生;食糜通过十二指肠刺激CCK等胃肠激素的分泌,有利于消化及营养的吸收;仅切断一端空肠及适度大小的代胃,保持了空肠与系膜原有的联系,既简化了手术,又保证了间置代胃空肠之血运,使吻合口无缺血坏死之忧。     

全胃切除后“SS”法空肠间置代胃术25例分析

我院2001年～2008年行全胃切除后“SS”法空肠间置代胃术25例，效果满意，现报告如下。临床资料1．一般资料：本组25例中，男性16例，女性9例；年龄27～76岁，平均57．4岁。本组均为进展期胃癌。其中，Ⅱ期7例，Ⅲ期18例。本组术前均经上消化道钡餐及电子胃镜病理检查确诊胃癌。病变部位：胃小弯侵及贲门2例，     

全胃切除ρ型间置空肠代胃术26例

全胃切除作为胃癌根治术的常用术式,由于胃功能丧失,病人可出现不同程度的无胃综合征,如反流性食管炎、倾倒综合征、摄食不足、消化不良、体重下降、贫血等。严重影响了病人的生活质量。我院自1999年12月至2010年11月,采用ρ型间置空肠代胃对26例行全胃切除术的胃癌病人进行消化道重建,效果较好,现报告如下。     

Free jejunal interposition reconstruction after pharyngolaryngectomy: 201 consecutive cases

Background. Reconstruction of tubular defects following pharyngolaryngectomy has required complicated surgery with high perioperative morbidity and mortality. Free jejunal interposition provides an excellent reconstruction with potential for lower immediate complications and better long-term results than other procedures. Methods. A total of 201 consecutive free jejunal interpositions were performed following pharyngolaryngectomy between 1977 and 1993. Operative details, complications, and outcome were prospectively documented. Results. Perioperative mortality was low (4.5%) and microvascular success rate high (97%), although a small number of late failures were recorded. Average time until swallowing postoperatively was 11 days, and 92% of patients could maintain full nutrition. Voice rehabilitation was mentioned, and increasingly good results are being obtained. Complication rates for the neck (17%) and the abdomen (2.5%) were also low. There were no problems with excess mucus production or reflux. Radiation effect on the jejunal conduit was not detrimental to long-term patency of the vascular anastomoses or to function as a conduit. Conclusions. Comparison with other published techniques permits the contention that a free jejunal interposition is the reconstruction of choice after pharyngolaryngectomy. © 1995 Jons Wiley & Sons, Inc.     

Gastrointestinal stromal tumor of the stomach successfully treated by laparoscopic proximal gastrectomy with jejunal interposition

The authors describe a patient with a bleeding gastrointestinal stromal tumor of the stomach who was treated successfully by laparoscopic proximal gastrectomy with jejunal interposition. Immunohistochemically, the tumor was positive for vimentin and CD34 and was diagnosed as a gastrointestinal stromal tumor of low-grade malignancy. Because it is difficult to diagnose this disease preoperatively and a malignant phenotype has been reported, resulting in liver metastasis and peritoneal dissemination, it is desirable to treat this disease with as little manipulation as possible. To achieve this, laparoscopic surgery is a feasible option for the treatment of gastrointestinal stromal tumors.     

Free jejunal interposition graft for reconstruction of the esophagus

Forty-seven patients underwent pharyngoesophageal reconstruction using a free jejunal interposition graft (FJIG) at Duke University Medical Center from 1978 through 1987. There were 30 men and 17 women with ages ranging from 38 to 87 years old (mean age, 64 years). Twenty-one patients (group A) had no prior surgical procedures, 20 (group B) were reconstructed following radiation and/or surgical failure, with 6 patients (group C) having benign strictures of the upper alimentary tract. Follow-up ranged up to 122 months (mean, 23 months), with 3 patients lost to follow-up, and 4 perioperative deaths (within 3 months of surgery). There were a total of 9 initial graft failures, 4 patients undergoing successful re-implantation, resulting in an overall success rate of 89% (42 of 47). Excluding patients with graft failures, perioperative deaths, and patients lost to follow-up, 33 of 36 patients with a viable FJIG were able to maintain adequate swallowing function yielding a physiologic success rate of 86%. All of the 21 patients dying of recurrent disease had excellent palliation with the FJIG. Of the 7 patients who are alive, only 1 has dysphagia secondary to stricture. In conclusion, it is felt that the FJIG is a sophisticated method of reconstructing large surgical defects of the pharyngoesophagus with a high technical and physiologic success rate.     

Comparing reconstruction with ileocecal graft to jejunal interposition pouch after total gastrectomy in rats.

After total gastrectomy, the ileocecal graft may act as a reservoir and protect against reflux but give rise to transposition of the ileum and cause possible changes in bile acid metabolism and nutrition. This study compared the ileocecal graft and jejunal pouch. Male Wistar rats weighing 265 +/- 22 g were submitted to sham operation (S), ileocecal interposition graft (IIG), and jejunal pouch interposition graft (JP) after total gastrectomy. Eight weeks later, the esophagus was examined for evidence of esophagitis. Nutritional biochemistry and weight profile were documented preoperatively and 8 weeks after surgery. The oral glucose tolerance test was performed. Thirty-three rats were operated on and 30 survived for 8 weeks. Esophagitis occurred in seven JP rats. Body weight was significantly higher in IIG than in JP rats (p < .05). Normal glucose tolerance to intragastric glucose load was observed in sham and operated rats. JP rats had a significant decrease in serum albumin, glucose, transferrin, hemoglobin, iron, folate, and calcium, compared to sham (p < .05). Cobalamine was significantly lower in IIG rats than in JP rats (p < .05). In the IIG and JP groups, serum/hepatic total bile acid did not differ significantly from preoperative and sham values. In conclusion, the IIG interposition graft in rats prevented esophagitis, preserved nutrition, and did not interfere with enterohepatic total bile acid circulation.     

Laparoscopically assisted total gastrectomy with jejunal pouch interposition

Background Jejunal pouch interposition (JPI) is known as a useful gastric replacement procedure after total gastrectomy. The JPI procedure, however, has not been applicable to laparoscopically assisted total gastrectomy (LATG) because of its technical complexity and difficulty. This study aimed to describe our modified LATG/JPI technique, and to evaluate its feasibility, safety, and early postoperative functional outcome. Methods Between September 2002 and August 2003, LATG/JPI was attempted for five patients (3 men and 2 women) with early gastric cancers in the upper portion of the stomach. The mean age of the patients was 57 years, and their BMI was 21 kg/m². Using a 5-port technique, the gastric arteries were laparoscopically clipped and divided with adequate lymphatic dissection. After completion of gastric resection, the anvil of a circular stapling device was placed in the esophageal stump. An 8-cm minilaparotomy then was performed, and the 12-cm pouch was created extracorporeally in the “reverse U” fashion. The stapled pouch-esophagostomy was performed under laparoscopic monitoring. The remainder of the procedure was accomplished under direct vision. Results All cases were managed laparoscopically without any complications. The mean operating time was 407 min, and the blood loss was 279 ml. All the patients showed rapid and uneventful recovery. Postoperative studies, including dual scintigraphy, showed that all jejunal pouches were satisfactorily functioning. Conclusions This study showed LATG/JPI to be feasible and safe. With technical modifications, LATG/JPI can become a potentially effective option for improving patients’ quality of life after total gastrectomy.     

全胃切除改良功能空肠间置法胃肠道重建

全胃切除术后并发的反流性食管炎、倾倒综合征、食欲减退、摄食不足、消化不良、体重下降及贫血等无胃综合征,严重影响患者生活质量,故应寻找一种合理的消化道重建方式。郝希山等[1]创用功能性空肠间置代胃术(functional je-junal interposition,FJI,1999年),我们认为更符合生理,并在此基础上进一步加以改良,报告如下。1资料与方法1.1一般资料2004年7月至2005年1月,术前通过胃镜病理确诊,全胃切除术后有完整病历资料的10例。男7例,女3例,年龄45~68岁。均为胃上、中部癌,贲门癌3例,胃体小弯侧5例,大弯侧1例,累及整个小弯1例。BorrmannⅢ型9…