PAROTOID TUMOURS: A STUDY OF 65 CASES

Sixty five patients who had undergone surgery for parotid tumours over a period of nine years were studied retrospectively. There were 45 males and 20 females. There were 49 benign and 16 malignant tumours. Age ranged 35-69 years; mean 47 years. Pain (6%) and facial palsy (3%) were unusual features. Size of tumour at presentation varied from 1.5 to 12 cm. Superficial parotidectomy was the commonest operation performed and Total/Radical/Extended parotidectomy was done in selected cases. Postoperative radiotherapy was used in six cases. No recurrences were noted following surgery for benign tumours. However a local recurrence rate of 37% was found for malignancies (6/16 cases). This paper aims to review the experience of managing these tumours in the setting of service hospitals.KEY WORDS: Carcinoma parotid, Parotid tumour, Pleomorphic adenoma     

腮腺肿瘤术后面神经功能损伤的多因素分析

目的:探讨腮腺肿瘤术后面神经功能损伤的发生率与手术方式、面神经解剖方式、病变性质、肿瘤位置以及手术次数等关系。方法:对本院2001年3月~2007年7月手术治疗的264例腮腺区病损患者的临床资料进行回顾性分析。结果:264例患者中有127例(占48%)术后出现面神经功能损伤。行浅叶及肿瘤切除手术比行全叶及肿瘤切除手术损伤面神经的概率低。良性肿瘤术后面神经损伤的机会较恶性肿瘤低,多次手术较首次手术发生损伤面神经的概率低,耳前、下颌骨后侧较耳后及耳下发生损伤面神经的概率高,良性病损术后多为暂时性面神经损伤;恶性病损,由于采用切除受累神经分支术式,术后面神经损伤多为永久性的。结论:面神经受损的危险性与手术切除范围、面神经解剖方式、病理性质、肿瘤位置及手术的次数等是密切相关的。     

功能性腮腺切除术在腮腺浅叶良性肿瘤手术中的应用

目的探讨功能性腮腺切除术在腮腺浅叶良性肿瘤手术中的临床应用价值。方法首诊腮腺浅叶单发良性肿瘤病例51例,肿瘤直径均≤3.0 cm,采用保留耳大神经、腮腺导管及部分腮腺、重建腮腺咬肌筋膜的功能性腮腺切除术治疗,距肿瘤边缘0.5～1.0 cm处的正常腺体组织内切除肿瘤,随访2个月～2年,观察术后并发症的发生及肿瘤复发情况。结果所有病例术后面部畸形较轻,腮腺功能良好,耳垂无明显麻木,无涎瘘及味觉出汗综合征,无永久性面瘫,其中5例出现暂时性面瘫。随访期间肿瘤无复发。结论功能性腮腺切除术手术创伤小,术后并发症少,在体积较小(≤3.0 cm)的腮腺浅叶良性肿瘤手术中具有很高的临床应用价值。     

腮腺肿瘤的MSCT诊断

目的通过回顾性分析肿瘤形状、边界、密度的均匀性、增强效果等形态学征象,总结腮腺肿瘤的MSCT表现,探讨腮腺肿瘤的诊断与鉴别诊断价值。方法收集经手术证实的24例腮腺肿瘤的MSCT资料,与病理改变进行对照分析。MSCT同时行平扫和增强扫描。结果腮腺肿瘤大多位于腮腺浅叶（14/24）,良性肿瘤以多形性腺瘤居多（13/19）,MSCT表现为境界清楚、密度均匀的肿块。恶性肿瘤以粘液表皮样癌较多（4/5）,MSCT多显示为境界不清、密度不均匀的肿块。转移癌以鼻咽部来源多见（1/5）。结论腮腺肿瘤在MSCT表现上有其各自特点,对绝大多数病例进行定性诊断是可能的。     

恶性腮腺肿瘤的B超预测

为了寻找有助于鉴别腮腺良，恶性肿瘤的超声征象，我们检测了２１例腮腺肿瘤患者，结果表明：利用超声检查，可显示出全瓣腮腺肿块，根据肿块的边界不清，包膜不完整肿块后方回声衰减等声像学征象，准确地预测出７例恶性肿瘤。     

腮腺肿瘤的MRI诊断

目的:通过回顾性分析肿瘤形状、边界、T1WI和T2WI信号强度、均匀性、增强效果等形态学征象,总结腮腺肿瘤的MRI表现,探讨腮腺肿瘤的诊断与鉴别诊断价值.方法:收集经手术证实的24例腮腺肿瘤的MRI资料,与病理改变进行对照分析.MR平扫采用T1WI、T2WI扫描,部分同时行平扫和增强扫描.结果:腮腺肿瘤大多位于腮腺浅叶(14/24),良性肿瘤以多形性腺瘤居多(13/19),MRI表现为境界清楚、信号均匀的肿块.恶性肿瘤以粘液表皮样癌较多(4/5),MRI多显示为境界不清、信号不均匀的肿块.转移癌以鼻咽部来源多见(1/5).结论:腮腺肿瘤在MRI表现上有其各自特点,对绝大多数病例进行定性诊断是可能的.     

头颈部恶性肿瘤累及颈动脉的治疗(附3例报告)

报告３例头颈部恶性肿瘤颈部转移累及颈动脉,术中保留预动脉,术后４～６ｄ颈动脉破裂大出血。分析原因为伤口感染和颈动脉已被肿瘤浸润所致,提示受肿瘤侵犯的颈动脉不宜保留。     

腮腺微小肿瘤的临床病理研究

目的: 探讨直径≤20 mm的体积微小的腮腺肿瘤临床病理特点,为临床诊疗提供参考依据。方法: 选择2012年12月至2020年4月于北京大学口腔医院口腔颌面外科手术治疗的腮腺肿瘤患者,收集术前CT检查肿瘤直径≤20 mm的患者相关临床资料,根据肿瘤直径大小分为直径11~20 mm组与直径≤10 mm组,对两组进行临床随访,比较一般情况、临床病理特点及预后。结果: 共收集原发性上皮性腮腺肿瘤患者2 067例,其中肿瘤直径≤20 mm者有685例(33.1%),男女性别比例为1 ∶1.93,平均年龄(45.3±13.8)岁(12~83岁),中位病程12个月(1周至30年)。685例中良性肿瘤635例(92.7%), 恶性肿瘤50例(7.3%),良恶性比例为12.7 ∶1;最常见的良性肿瘤为多形性腺瘤,最常见的恶性肿瘤为黏液表皮样癌。肿瘤直径≤10 mm的患者有74例,占肿瘤直径≤20 mm患者的10.8%(74/685)。肿瘤直径11~20 mm组(n=611)和≤10 mm组(n=74)患者的一般情况及病理学分型比较提示,两组在性别、年龄、病程上差异均无统计学意义(P>0.05)。直径11~20 mm组患者良性肿瘤占92.8%(567/611), 恶性肿瘤占7.2%(44/611), 良恶性比例为12.9 ∶1;直径≤10 mm组良性肿瘤占91.9%(68/74), 恶性肿瘤占8.1%(6/74),良恶性比例为11.3 ∶1,两者间差异无统计学意义(P>0.05)。对50例恶性肿瘤患者进行临床随访,中位随访时间为39.5个月(1~91个月),有2例患者局部复发,其中1例死亡,总体2年生存率为93.7%, 5年生存率为89.3%。结论: 直径≤20 mm的体积微小的腮腺肿瘤以良性多见,手术是主要治疗手段,其中的腮腺恶性肿瘤预后良好,应积极进行早期手术治疗。     

腮腺区肿瘤的CT和MRI诊断及病理联系

目的探讨CT和MRI对腮腺区肿瘤的诊断价值.方法对72例腮腺区肿瘤(良性36例,恶性36例)进行CT和MRI检查,检查结果与术后病理进行对照.结果腮腺肿瘤大多位于腮腺浅叶(44/72),良性肿瘤以混合瘤居多(26/36),CT和MRI表现为境界清楚、密度均匀的肿块,CT和MRI测量结果与术后病理大小一致;恶性肿瘤以粘液表皮样癌较多(14/28),CT和MRI多显示为境界不清、密度不均的肿块,术前测量大小常小于术后病理结果;转移癌以鼻咽部来源多见(6/8).72例腮腺肿瘤中,术前定位准确率为100%,良恶性性质判断准确率为95.8%.结论CT和MRI对腮腺区肿瘤的定位、定最及定性较为准确,具有较大的价值,对面神经的显示MRI优于CT.     

腮腺良性肿瘤的外科手术治疗方式及其并发症分析

目的 回顾性分析腮腺良性肿瘤的外科手术治疗方式的选择及其并发症.方法 收集我院2007-2011年间83例腮腺良性肿瘤患者,行腮腺部分切除术21例,腮腺浅叶切除术43例,全腮腺切除术19例,随访1～4年,分析其手术效果及并发症.结果 在本组病例中,均无肿瘤复发及永久性面瘫;在腮腺部分切除术中,暂时性面瘫发生率为14.3％ （3/21）,Frey综合征为4.8％ （1/21）.在腮腺浅叶切除术中,暂时性面瘫为39.5％ （17/43）,涎瘘为14％ （6/43）,Frey综合征为16.3％ （7/43）.在全腮腺切除术中,出现暂时性面瘫发生率为52.6％ （10/19）,涎瘘为10.5％ （2/19）,Frey综合征为15.7％ （3/19）.结论 腮腺部分切除术并发症少,但有严格的手术适应证,腮腺浅叶切除术手术疗效肯定,但并发症较多,术中尽量保护面神经,保留腮腺导管、耳大神经.全腮腺切除术术后暂时性面瘫发生率最高.三种术式均有严格的适应证,不同部位的腮腺肿瘤应采用不同的手术切除方式,以减少并发症的发生.     

Parotidectomy--a prospective study

Preservation of facial nerve is a real challenge in parotidectomy. Total conservative parotidectomy and superficial parotidectomy are the commonly practised operations for parotid diseases. Twelve patients have undergone total conservative parotidectomy and 52 patients have undergone superficial perotidectomy with preservation of integrity and function of the facial nerve and its branches. Fifty-eight patients were suffering from neoplastic conditions of which 46 had pleomorphic adenoma, 7 had muco-epidermoid carcinoma, 3 had carcinoma ex-pleomorphic adenoma, and 2 had adenoid cystic carcinoma. Non-neoplastic conditions were seen in 6 cases of which 3 had chronic parotitis and 3 had congenital parotid fistula. The aim of the study was to observe the efficacy of preservation of facial nerve in parotidectomy done in 64 patients.     

Salivary gland tumours: profile and management at a tertiary cancer centre

Salivary gland tumours comprise a varied group of benign and malignant neoplastic lesions posing a challenge to surgeon. To review the profile of salivary gland tumours presenting to a referral cancer centre and their overall management, a retrospective analysis of prospective head and neck cancer database of the surgical oncology department of Institute Rotary Cancer Hospital (IRCH), All India Institute of Medical Sciences (AIIMS) was performed. Forty patients of salivary gland tumours treated between 1995 and 2003 were analysed. All computations including recurrences and survival were carried out using the statistical package for social sciences (SPSS) for windows software (SPSS Inc, USA). The profile of salivary gland tumours presenting to a cancer centre setting was found to be different - 77.5% being malignant tumours and the remaining 22.5% werebenign tumours. Most common site of involvement was the parotid gland (72.5%). Muco-epidermoid carcinoma and adenocarcinomas were the most common histological types. Conservative resection was adequate for benign tumours. For primary malignant tumours, radical surgery with or without neck dissection and appropriate reconstruction, combined with postoperative radiotherapy was effective in achieving good locoregional control. Optimal management of primary tumour along with appropriate neck dissection including resection of the involved salivary gland is necessary for the management of metastatic salivary gland tumours.     

保留腮腺嚼肌筋膜瓣对腮腺肿瘤术后复发的影响

目的评价在腮腺肿瘤切除术中保留腮腺嚼肌筋膜瓣对腮腺肿瘤术后复发的影响。方法236例良性腮腺肿瘤患者随机分为两组,保留腮腺嚼肌筋膜瓣组（I组）141例,按传统手术方法未保留腮腺嚼肌筋膜组（Ⅱ组）95例。术后3～5年对肿瘤复发情况进行随访。结果I组和Ⅱ组患者术后肿瘤复发率分别为3．6％（5／141例）和4．2％（4／95例）,经统计学处理无显著性差异（P〉O．05）。结论保留腮腺嚼肌筋膜不会增加良性腮腺肿瘤的复发。     

Pattern of ovarian neoplasm in Manipur

Of 158 cases of ovarian neoplasm seen within a period of 12 years in the department of pathology, Regional Medical College, Imphal 118 (74.68%) cases were benign and 40 (25.32%) were malignant. Surface epithelial tumours were the commonest being 66.45%. Ovarian carcinoma constituted 12.08% of all malignant gynaecological diseases and it formed the 2nd commonest gynaecological malignancy after carcinoma of the cervix. The peak incidence of benign tumours were in the age group of 21 to 30 years while that of malignant tumours were in the age group of 31 to 50 years.     

Aggressive treatment of metastasis to the parotid

OBJECTIVES: Assess the value of aggressively treating metastatic lesions in the parotid, taking into account the histology of the disease. STUDY DESIGN: Retrospective analysis of 13 patients diagnosed with metastasis to the parotid treated by one surgeon in a tertiary referral head and neck unit in the United Kingdom. METHODS: The following variables were reviewed and tabulated: age, sex, histology, latent period to secondary tumour, treatment instituted, postoperative facial nerve outcome, follow-up and survival. RESULTS: Twelve patients were treated aggressively with at least total parotidectomy and adjunctive therapy, whilst one patient required only a superficial parotidectomy. Ten patients had metastatic cutaneous tumours, and three had metastatic adenocarcinoma. Seven of these 13 patients (53.8 %) are alive and well (six had metastatic cutaneous tumours, one had metastatic adenocarcinoma). Four patients succumbed to tumour (two had metastatic cutaneous tumours and two had metastatic adenocarcinoma), and two patients succumbed from unrelated medical causes (both had metastatic cutaneous tumours). The mean follow-up for those alive is 65.9 months and mean follow-up for those deceased is 15.3 months. CONCLUSIONS: In the absence of systemic spread, parotid metastases from primary cutaneous squamous cell carcinoma should be treated aggressively, while metastases from non-cutaneous primary tumours should be approached with caution.     

腮腺肿瘤的高频彩超诊断

目的探讨高频彩超对腮腺肿瘤诊断价值。方法回顾性分析经手术及病理证实的195例腮腺肿瘤的二维声像图及彩色多普勒血流显像特点。结果 195例腮腺肿瘤中,良性肿瘤163例,超声诊断符合率为78.5%,恶性肿瘤32例,超声诊断符合率为68.8%。结论高频彩超对腮腺肿瘤的检出率较高,对腮腺肿瘤要做到病理学诊断有一定难度。     

345例腮腺肿瘤临床分析

[目的]通过对我院近10年345例腮腺肿瘤的统计分析,探讨其发病原因、最佳治疗方案,提高腮腺肿瘤患者的治愈率及生存质量.[方法]回顾我院近10年的腮腺肿瘤病例,随访其治疗效果及生存质量,进行统计分析.[结果]345例腮腺肿瘤中,良性301例,恶性44例.良性肿瘤如多形性腺瘤、沃辛瘤的发病有增多的趋势.345例腮腺肿瘤患者中,326例行保留面神经、腮腺浅叶或全叶切除术,19例沃辛瘤患者行腮腺区域性切除术.术后效果良好,无面神经损伤及肿瘤复发病例.行腮腺区域性切除术者,无面部凹陷畸形、味觉出汗综合征,较好地保存了患侧腮腺功能.[结论]腮腺良性肿瘤有增多的趋势,warthin瘤等好发腮腺后下极的肿瘤行腮腺区域性切除术,术后效果良好,保存了腮腺的功能,提高了患者的生存质量.     

腮腺下极良性肿瘤术后味觉出汗综合征的预防研究

目的：回顾分析不同手术处理方式对腮腺下极良性肿瘤术后味觉出汗综合征的预防作用。方法将临床收治的122例腮腺下极（包括后下极）良性肿瘤病例随机分为A,B,C,D 4组,A组作为对照组,采用传统腮腺腺叶及肿瘤切除术,B组应用单纯腮腺部分切除术,C组行保留腮腺筋膜的腮腺部分切除术,D组腮腺部分切除术后,术区覆盖异种脱细胞真皮基质。术后随访12～36个月,通过Minor试验了解味觉出汗综合征情况。结果 A组41例患者发生味觉出汗综合征24例（58．54％）。 B组35例,发生12例（34．29％）。 C组26例,发生3例（11．54％）。 D组20例,查见2例（10．00％）。 A组与B,C,D 3组任何一组比较,均存在差异（ P＜0．05）。 B组与C,D任意一组间比较,均存在差异（P＞0．05）,C,D两组间差异不明显（P＞0．05）。结论对于腮腺下极良性肿瘤,腮腺部分切除术后保留腮腺筋膜或应用异种脱细胞真皮基质均可有效预防术后味觉出汗综合征的发生,但脱细胞真皮基质应用范围更为广泛。     

保留腮腺功能的腮腺浅叶部分切除术

目的:总结腮腺良性肿瘤保留腮腺功能的浅叶部分切除术的效果.方法:通过对泸州医学院附属医院口腔颌面外科最近2年来50例腮腺浅叶肿瘤患者,采取保留腮腺功能的浅叶部分切除术进行回顾分析,评价腮腺的分泌功能,面神经损伤情况,面部外形改变,唾液积潴,术后复发.结果:经过1年～2年的门诊复诊及随访发现,面部外形无凹陷畸形,无永久性面瘫,无涎瘘形成.保留的残余腺体有涎液分泌,肿瘤无复发.结论:认为保留腮腺功能的浅叶部分切除术是一种可行性术式并具有较好的临床价值.     

腮腺良恶性病变的MSCT影像表现及鉴别诊断

目的 探讨腮腺良恶性病变的CT表现和诊断价值.方法 回顾性分析经病理证实的腮腺良恶性病变30例CT表现.结果 30例病灶,22例良性病灶,8例恶性肿瘤病灶;其中右侧病变13例,左侧病变17例;腮腺浅叶病变19例,深叶病变6例,浅深叶交界病变5例;4例良性病变边缘不清,术前误诊为恶性肿瘤,2例恶性肿瘤边缘清楚,术前误诊...