Factors influencing plasma butyrylcholinesterase activity in agricultural workers

We studied the influence of some factors on plasma butyrylcholinesterase activity (BChE) and we assessed the health status of agricultural workers and looked for the effects of chronic exposure to pesticides, in the aim to determinate factors that must be considered for interpretation of BChE, for occupational monitoring of workers exposed to pesticides. The study was carried out in 110?workers from the Sahel region of Tunisia exposed to pesticides and in 97 controls. All individuals have undergone clinical examination. BChE activity was measured by spectrophotometric method. The mean of BChE activity of workers was significantly lower than that of control group (P?相似文献   

Respiratory allergy in agricultural workers: recent developments

PURPOSE OF REVIEW: To review recent evidence on the relationship between occupational exposure to allergens and asthmagens, and risk for developing allergy and asthma and the role of modifying factors in farmers and farm workers. RECENT FINDINGS: Recent studies identified agents that have not been associated with allergy or asthma in farming populations before. The most intriguing findings, however, are those that suggest that the development of atopy and asthma might be influenced by exposure to pathogen associated molecular patterns (PAMPs), including endotoxin. SUMMARY: The adverse and potentially protective effects of microbial exposures in the farm environment are discussed. Recent findings indicate that it is very likely that the protective effect of exposure to PAMPs such as endotoxin is not limited to childhood age. The protective effects that probably developed during childhood can still be observed at adult age. Furthermore, it even seems likely that exposures at adult age (in occupational environments), which stimulate the innate immune system, have an effect on allergy, independently of childhood exposure. It is hypothesized that reversal of atopy might occur as a result of high exposure to endotoxins and other PAMPs.     

基于WEB技术的医疗咨询服务平台的应用

本文主要讲述了医院如何利用计算机软件工程、互联网络技术、语音处理技术、移动通讯技术等高新技术结合现代医疗管理模式,以患者电子病历信息库为基础建立患者医疗咨询服务平台.以有效解决患者来院就诊前和在医院就诊结束离开医院后的医疗咨询与跟踪服务的需要,更加有效地为来医院就诊的患者提供更方便、更快捷、更体现人性化的服务.     

医用植入通信服务标准

医用植入通信服务（MICS）是针对医用植入装置间的低功耗、短距离无线通信服务,已在世界范围内被广泛使用.建立国际统一的MICS通信标准十分必要.主要从技术参数、兼容性、抗干扰方法以及数据传输的可靠性等4个方面详细说明了国际电信联盟ITU-R SA.1346标准;介绍了植入式医学通信服务标准在欧洲和美国等地的应用,并对不同地区的技术准则进行了对比分析.     

Lasiodiplodia theobromae onychomycosis among agricultural workers: A case series

Lasiodiplodia theobromae is a dematiaceous non-dermatophyte mold (NDM), rarely reported to cause onychomycosis. Here, we report three cases of toenail onychomycosis caused by L. theobromae in agricultural workers. Two patients presented with total dystrophic onychomycosis and one with distal and lateral subungual onychomycosis. These cases have unique importance that besides traumatized nail infection, its rarity has adversely affected the agricultural workers livelihood as L. theobromae sporulates poorly, resistant to commonly used antifungal therapy. From the literature search, we assume that this is the first case series of onychomycosis caused by L. theobromae from a tropical country like India.     

Cytogenetic damage in female Pakistani agricultural workers exposed to pesticides

Bhawalpur is a major cotton-growing area in Pakistan. Cotton picking in Pakistan is carried out by females and as a result of the intensive use of pesticides during the growing season these females are exposed to pesticide residues in the picking season. In the present study, peripheral blood was obtained from 69 cotton pickers and 69 unexposed females and used to assess the effect of pesticide exposure on genetic damage as well as on hepatic enzymes and serum cholinesterase. The subjects were of similar average age in workers and control groups (37.55 +/- 12.75 vs. 37.52 +/- 13.47, P > 0.05). Average exposure time of the picker females was 10.26 +/- 6.14 years. Subjects from the exposed group did not use any protective measures during their work activities. Levels of serum cholinesterase were lower, and levels of alkaline phosphatase, alanine aminotransferase, and aspartate aminotransferase were higher in the exposed workers as compared with the control group (P < 0.001). The exposed group exhibited significantly increased frequencies of binucleated cells with micronuclei (12.72 +/- 3.48 vs. 4.35 +/- 2.44, P < 0.001) and total number of micronuclei in binucleated lymphocytes (16.51 +/- 4.27 vs. 5.86 +/- 3.09, P < 0.001) in comparison with subjects of the control group. The binucleated cells with micronuclei frequency also seemed to increase with age in both the groups, however, the magnitude of increase was greater in exposed group than the control. Results from the present study indicate that occupational exposure to pesticide mixtures results in cytogenetic damage in exposed females.     

数字化医学图书馆的读者服务新探

简要探讨了数字化医学图书馆读者服务的新优势,在这种新优势下为读者服务提供的新方式,以及数字化网络信息在读者服务工作中的运用,给医学图书馆的读者服务工作带来的新变革.