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Background

Hip fracture risk is high in young people with multiple sclerosis (MS), but has not been examined in an institutionalized aging population with MS.

Objective

We aimed to compare the hip fracture risk in nursing home (NH) residents with and without MS; and (2) examine risk factors for hip fracture in those with MS.

Methods

We conducted a retrospective cohort study using national NH clinical assessment and Medicare claims data. Participants included age-, sex- and race-matched NH residents with/without MS (2007–2008). Multivariable competing risk regression was used to compare 2-year hip fracture risk, and to examine risk factors.

Results

A total of 5692 NH residents with MS were matched to 28,460 without MS. Approximately 80% of residents with MS vs. 50% of those without MS required extensive assistance in walking at NH admission. The adjusted incidence rate of hip fracture was 7.1 and 18.6 per 1000 person-years in those with or without MS, respectively. Wandering and anxiolytic exposure were the main hip fracture risk factors in transfer independent residents with MS; while pneumonia and antidepressant use were the main factors in dependent residents with MS.

Conclusions

In contrast to prior comparisons from non-NH populations, the incidence of hip fracture was lower in NH residents with MS as compared with matched controls. Residents with MS were much more functionally dependent, which likely explains these findings. Fracture prevention strategies should focus on fall prevention in independent residents; and possibly improvement of health status and facility quality of care in dependent residents.  相似文献   

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OBJECTIVE: To explain variation in direct care resource use (RU) of nursing home residents based on the Resource Utilization Groups III (RUG-III) classification system and other resident- and unit-level explanatory variables. DATA SOURCES/STUDY SETTING: Primary data were collected on 5,314 nursing home residents in 156 nursing units in 105 facilities from four states (CO, IN, MN, MS) from 1998 to 2004. Study Design. Nurses and other direct care staff recorded resident-specific and other time caring for all residents on sampled nursing units. Care time was linked to resident data from the Minimum Data Set assessment instrument. Major variables were: RUG-III group (34-group), other health and functional conditions, licensed and other professional minutes per day, unlicensed minutes per day, and direct care RU (wage-weighted minutes). Resident- and unit-level relationships were examined through hierarchical linear modeling. DATA COLLECTION/EXTRACTION METHODS: Time study data were recorded with hand-held computers, verified for accuracy by project staff at the data collection sites and then merged into resident and unit-level data sets. PRINCIPAL FINDINGS: Resident care time and RU varied between and within nursing units. RUG-III group was related to RU; variables such as length of stay and unit percentage of high acuity residents also were significantly related. Case-mix indices (CMIs) constructed from study data displayed much less variation across RUG-III groups than CMIs from earlier time studies. CONCLUSIONS: Results from earlier time studies may not be representative of care patterns of Medicaid and private pay residents. New RUG-III CMIs should be developed to better reflect the relative costs of caring for these residents.  相似文献   

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OBJECTIVE: Antibiotic exposure is a risk factor for isolation of methicillin-resistant Staphylococcus aureus (MRSA). We reasoned that this relationship might be especially strong if the comparison was targeted to antibiotics with activity against methicillin-sensitive Staphylococcus aureus (MSSA), but not MRSA. SUBJECTS: Forty-eight cases with initial MRSA clinical isolates (15 urinary, 19 wound, 11 sputum, 3 blood) were matched to 48 with MSSA clinical isolates from the same location. In addition, 10 whose MRSA was noted screening around an index case were matched to 10 with negative screening cultures sampled around the same index case. DESIGN: MSSA was always/usually sensitive to dicloxacillin, amoxicillin/clavulanate, cephalosporins, imipenem, quinolones, and erythromycin, whereas MRSA was always/usually resistant. These antibiotics were defined as "targeted" and would be expected to facilitate the proliferation of MRSA by suppressing competing bacteria. We compared the use of all antibiotics over 60 days in cases and controls. RESULTS: The comparison of antibiotic exposure in the 48 clinical isolates revealed that 29 (60%) with MRSA isolates versus 16 (33%) with MSSA isolates had received a targeted antibiotic (RR 1.81, CI 1.33-3.34, P = 0.006). Twelve (25%) with MRSA clinical isolates versus 3 with MSSA isolates (6%) had received a nontargeted antibiotic (RR 4.00, CI 2.10-14.18, P = 0.009). The comparison of antibiotic exposure in MRSA screening isolates versus negative controls revealed that 7 (70%) had received a targeted antibiotic versus 2 (20%) of controls (RR 3.50, CI 1.57-16.85, P = 0.009)). One in the screening group versus 2 controls had received a nontargeted antibiotic. Twenty-one (62%) of 34 with MRSA (urine or wound) isolates versus 4 MSSA controls (12%) had received a quinolone (RR 5.25, CI 1.80-15.30, P < 0.000). CONCLUSION: There was a significant association between antibiotic exposure and MRSA isolates. The association was especially strong for quinolones with urinary or wound isolation of MRSA. Our data do not support the hypothesis that targeted antibiotic use was more likely to be associated with MRSA isolation than nontargeted antibiotic use. The use of nontargeted antibiotics was low, with greater use in the MRSA clinical group.  相似文献   

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OBJECTIVE: To characterize Medicare skilled nursing facility (SNF) residents who become acutely ill with heart failure (HF) and assess the association between the outcomes of rehospitalization and mortality, and severity of the acute exacerbation, comorbidity, and processes of care. DESIGN: SNF medical record review of Medicare patients who developed an acute exacerbation of heart failure (HF) during the 90 days following nursing home admission. SETTING: A total of 58 SNFs in 5 states during 1994 and 1997. PARTICIPANTS: Patients with 156 episodes of acute HF among 4693 random Medicare nursing home admissions. MEASUREMENTS: Demographic variables, symptoms, signs, comorbidity, nursing home characteristics, nurse staffing ratios, and processes of care were compared between acute HF subjects transferred to hospital and those not transferred; and between subjects who died within 30 days of an acute exacerbation and those who survived. RESULTS: After adjusting for age, disease severity, and comorbidity, residents whose change in condition was evaluated during the night shift were more likely to be hospitalized (OR 4.20, 95%CI 1.01-17.50). Residents who were prescribed an angiotensin-converting enzyme inhibitor or who received an order for skilled nursing observation more often than once a shift were 1/3 as likely to die as those who did not (OR 0.303, 95%CI 0.11-0.82), after adjusting for hypotension, delirium, do not resuscitate orders, and prior hospital length of stay. CONCLUSION: For residents who develop an acute exacerbation of HF during a SNF stay, there is an association between attributes of nursing home care and the outcomes of rehospitalization and mortality.  相似文献   

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Objectives: To improve nursing home (NH) staff delivery of oral liquid nutritional supplements between meals to residents with a history of weight loss.Design: Pre-Post intervention study.Setting: Two skilled nursing homes.Participants: Eighteen long term care residents.Intervention: At baseline all participants had a non-specific physician’s order to receive a nutritional supplement. The intervention consisted of specifying the physician’s order as follows: “Give 4 oz high protein supplement at 10am, 2pm, and 7pm”.Measurements: Research staff conducted direct observations for two days during and between meals for a total of 4 days, or 12 possible observation periods per participant before and one week following the intervention. Research staff documented NH staff delivery of snacks (including high protein supplements) and amount consumed (fluid ounces) for the high protein supplements using a standardized protocol during each observation period.Results: Before the specific order was written participants were offered any type of snack an average of 1.82 times per day and a high protein supplement 0.59 times per day. After the specific order was written participants were offered any type of snack an average of 1.59 times per day and a high protein supplement 0.91 times per day. There were no statistically significant differences in the average number of times snacks or supplements were offered before and after the specific order was written. The proportion of snacks offered that were high protein supplements did increase after the specific order was written (p<0.001). When a high protein supplement was provided, most residents consumed 100% of it.Conclusions: Oral liquid nutritional supplements were not provided consistent with orders in NH practice. The specificity of the order related to type of supplement and time of delivery did not influence when and how often supplements are provided to residents but it did influence the type of nutritional supplement offered.  相似文献   

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Objective The purpose of this paper is to summarize the best evidence regarding the impact of providing patient-reported outcomes (PRO) information to health care professionals in daily clinical practice. Methods Systematic review of randomized clinical trials (Medline, Cochrane Library; reference lists of previous systematic reviews; and requests to authors and experts in the field). Results Out of 1,861 identified references published between 1978 and 2007, 34 articles corresponding to 28 original studies proved eligible. Most trials (19) were conducted in primary care settings performed in the USA (21) and assessed adult patients (25). Information provided to professionals included generic health status (10), mental health (14), and other (6). Most studies suffered from methodologic limitations, including analysis that did not correspond with the unit of allocation. In most trials, the impact of PRO was limited. Fifteen of 23 studies (65%) measuring process of care observed at least one significant result favoring the intervention, as did eight of 17 (47%) that measured outcomes of care. Conclusions Methodological concerns limit the strength of inference regarding the impact of providing PRO information to clinicians. Results suggest great heterogeneity of impact; contexts and interventions that will yield important benefits remain to be clearly defined.  相似文献   

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PURPOSE: The assessment and management of dementia, falls and mobility disorders, malnutrition, end-of-life issues, pressure ulcers, and urinary incontinence have been identified as important quality improvement targets for vulnerable elders residing in nursing homes. This study aimed to identify valid and feasible measures of specific care processes associated with improved outcomes for these conditions. METHODS: Nine experts in nursing home (NH) care participated in a modified Delphi process to evaluate potential quality indicators (QIs) for care in NHs. Panelists met and discussed potential indicators before completing confidential ballots rating validity (process associated with improved outcomes), feasibility of measurement (with charts or interviews), feasibility of implementation (given staffing resources in average community NHs), and importance (expected benefit and prevalence in NHs). The NH panel's median votes were used to identify a final set of QIs that were subsequently reviewed by a clinical oversight committee. RESULTS: Sixty-eight geriatric syndrome QIs were identified as valid and important in NH populations. Panelists assessed 12 (18%) of these QIs as having questionable feasibility to implement in average community nursing homes trying to provide quality care. Nine (13%) would not be included in systems assessing quality of care for persons with advanced dementia or poor prognosis. CONCLUSIONS: Steps of care critical to the assessment and management of geriatric syndromes in NHs were identified. Feasibility is an important issue for a significant number of these, indicating that much remains to be done to design systems that efficiently and reliably implement these care processes.  相似文献   

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Improving nursing home care has been a central legislative focus since the 1980s; The major response effort to address these reports of poor-quality care was first met with a federal rule in 1987, the Nursing Home Reform Act (NHRA). Since enactment of the NHRA in 1987, and despite an increasing utilization of nursing home care by aging minorities, the standardization of care practice, or quality indicators (e.g., structural, process, and outcome measures), within long-term nursing home care have remained relatively unchanged. This paper reports a value-critical policy analysis of the most recent final action rule, effective on November 28 of 2016 by the Centers for Medicare and Medicaid Services (CMS) with a particular focus on its impact on African-American and Latino older adults. This paper presents results of two policy analyses. Taken together, this merged analysis focuses on an overview of the problem, the groups most affected by the problem, current program goals and objectives, forms of benefits and services, and a current state of the social problem. Following the analysis, we present changes and improvements to be made, as well as proposals for reform and recommendations for policy changes.  相似文献   

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PURPOSE: The purpose of this study was to develop a set of specific care processes associated with better outcomes for general medical conditions identified as quality improvement targets for institutionalized vulnerable elders. METHODS: A national panel of nursing home experts used a modified-Delphi process to rate the validity (process linked to improved outcomes) and feasibility (of implementation and measurement) of candidate measures for depression, diabetes, hearing impairment, heart failure, hypertension, ischemic heart disease, osteoarthritis, osteoporosis, pneumonia, stroke, and vision impairment. Each quality indicator was written as an "if" statement, describing persons to whom the quality indicator applied followed by a "then" statement identifying the care process to be provided. A separate clinical committee reviewed the resulting set of indicators. RESULTS: One hundred fourteen quality indicators were identified across the 11 medical conditions. The quality indicators capture a broad range of medical care addressing assessment, management, and follow up. Fifty-five indicators (48%) were identical to quality measures for community-dwelling vulnerable elders. A limited number were rated as questionably feasible to implement or measure (6 and 2, respectively). Thirty-eight (33%) would not be applied to measures of care quality for persons with advanced dementia or poor prognosis. CONCLUSIONS: Explicit care processes linked to improved nursing home outcomes for general medical conditions can be identified. Most of these care processes can be measured by medical records or interview. Nursing home quality measures for medical conditions must account for exclusions related to poor prognosis and advanced dementia.  相似文献   

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临床实验性护理研究期刊论文的伦理审查状况分析   总被引:3,自引:0,他引:3  
【目的】了解国内护理期刊伦理审查状况及存在问题,以促进护理期刊的伦理学正确导向作用。【方法】以2014年版中国科技期刊引证报告(核心版)纳入的护理期刊为研究对象,分析2013—2014年国内12家护理学类统计源期刊刊发临床实验性护理研究论文的伦理审查状况。【结果】我国12家护理统计源期刊近2年共刊发论文21080篇,其中临床实验性护理研究论文4799篇(22.8%)。文内提及患者或家属对研究知情同意的比例仅占临床实验性护理研究论文的41.2%(22.6%~81.5%),仅19.9%的论文在文内提及研究经伦理委员会批准(0%~64.6%)。【结论】目前我国护理期刊伦理审查状况不容乐观,亟待提高期刊编审人员伦理审查意识,以促进临床实验性护理研究的伦理学规范。  相似文献   

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