高频彩色多普勒超声在乳腺肿瘤诊断中的应用价值

目的探讨高频彩色多普勒超声对鉴别乳腺良恶性肿块的应用价值。方法对86例经手术病理确诊的乳腺疾病患者（56例良性,30例恶性）进行术前彩超检查,对比性分析了两组间高频声像图、彩色多普勒血流成像（CDFI）、病灶内血流Adler分级、阻力指数（RI）、峰值流速（PSV）的差异。结果乳腺良恶性肿块声像图鉴别以肿块边界及形态特征最重要,彩色多普勒显示乳腺癌内的血流较良性肿块明显丰富（P〈0．05）,乳腺癌的血管分布异常、频谱多普勒示肿块内动脉血流PSV、RI也是显著高于良性肿块且有显著性差异（P〈0．05）。结论综合分析和评价血流Adler分级及频谱多普勒各项血流动力学参数（PSV,RI）指标,有助于对乳腺良恶性肿块的鉴别。     

彩色多普勒超声血流参数测定在乳腺良、恶性肿块鉴别诊断中的价值

目的:评价彩色多普勒超声血流参数(RI、PI、Vmax)在乳腺良、恶性肿块鉴别诊断中的价值.材料和方法:运用高频彩色多普勒超声诊断仪对408个乳腺肿块进行血流检测,对其中超声检出血流的340个乳腺肿块进行多普勒血流参数测定,比较多普勒血流参数在乳腺良、恶性肿块中的差异并对其诊断敏感性、特异性加以分析.结果:乳腺恶性肿块的RI、PI、Vmax值明显高于良性肿块(P<0.001),以RI≥0.72或PI≥1.3或Vmax≥13cm/s诊断乳腺癌,其敏感性和特异性最高,分别为85.5%和82.9%、80%和83.6%、70.1%和82.7%,其中以RI≥0.72的恶性似然比最高为5.0.彩色多普勒超声与灰阶超声征象相结合可使乳腺恶性肿块的超声诊断敏感性和特异性分别达97.6%和93.9%.结论:彩色多普勒超声血流参数测定对乳腺良、恶肿块的鉴别诊断具有重要的参考价值,与肿块的灰阶声像图征象相结合可明显提高乳腺肿块的超声诊断准确率.     

彩色多普勒超声血流阻力指数结合CA125对卵巢肿瘤的诊断价值

目的探讨彩色多普勒超声血流阻力指数(RI)结合肿瘤标志物CA125判断卵巢肿瘤良恶性的价值.资料与方法107例卵巢肿瘤患者采用Finkler 超声评分系统进行评分,经彩色多普勒超声检查测定 RI,同时测定患者血清 CA125判断卵巢肿瘤良恶性,并与术后病理进行对照.结果恶性卵巢肿瘤患者 Finkler 超声评分明显高于良性卵巢肿瘤患者,RI 值低于良性卵巢肿瘤患者,CA125明显高于良性卵巢肿瘤患者(P <0.01、P <0.05).Finkler超声评分、RI 结合 CA125对卵巢肿瘤良恶性诊断的敏感性及特异性分别为94.59%、89.47%,均高于单一检查方法.结论彩色多普勒超声、RI 及肿瘤标志物 CA125联合应用对提高卵巢肿瘤良恶性的诊断有一定临床价值.     

能量多普勒超声对乳腺良恶性肿瘤血流形态学及动力学指标的分析

目的:将能量多普勒超声用于乳腺良恶性肿瘤血流形态学及动力学的分析,试图为临床提供更多的乳腺癌早期诊断有价值的信息。方法:术前1周运用能量多普勒超声对76例乳腺良恶性肿瘤患者原发灶的血流形态学以及动力学指标进行分析。结果:能量多普勒检测乳腺良恶性肿瘤的彩色血流分级总体统计学有显著性差异(P<0·05),Ⅲ级血流信号的检出是乳癌的非常重要的指标(P<0·05)。但χ2分割后发现良恶性肿瘤在血流分级Ⅱ级有部分重叠,且25%的良性肿瘤可检出Ⅲ级血流信号。良性肿瘤以分支型和散在星点状为主,其中散在星点状为最多见的良性肿瘤血管形态学特征。恶性肿瘤以中央穿入型和分支型为主(P<0·05),其中中央穿入型为最多见的恶性肿瘤血管形态学特征。只有肿瘤内部的Vmax在鉴别乳腺肿瘤良恶性方面统计学有显著性差异(P<0·05),肿瘤周边血管的血流动力学参数和肿瘤内的RI在鉴别乳腺肿瘤的良恶性方面无统计学意义。如果用百分位数法求得肿瘤内部Vmax:13cm/s为鉴别乳腺肿瘤的良恶性的最佳界值,其敏感性,特异性分别为86%,83%。结论:能量多普勒超声对乳腺良恶性肿瘤血流形态学及动力学指标的检测可为临床提供更多的乳腺癌早期诊断的有价值的信息。     

彩色多普勒超声对乳腺良恶性肿块的鉴别诊断价值

目的应用彩色多普勒血流显像（CDFI）观察乳腺肿块的血流特点，评价血流参数（PSV、R0对乳腺良、恶性肿块的鉴别诊断价值。方法运用CDFI检测73例的77个乳腺肿块，并与术后病理对照。对其中超声检测出血流的60个乳腺肿块观察血流特点并进行血流参数测定，比较乳腺良、恶性肿块的差异，同时对RI诊断的敏感性、特异性、阳性预测值、阴性预测值加以分析。结果乳腺恶性肿块的CDFI血流信号较良性肿块明显丰富。恶性肿块的PSV、RI值明显高于良性肿块CP〈O．05），以RI≥0．70诊断乳腺癌敏感性和特异性较高，分别为82．6％和80．95％。结论彩色多普勒血流显像及血流参数测定对乳腺良、恶肿块的鉴别诊断具有重要的参考价值。     

乳腺良恶性病变血流分级与收缩期峰值和阻力指数的相关性研究

目的探讨乳腺病变的血流分级与收缩期峰值（PSV）和阻力指数（RI）的相关关系及其对良恶性病变鉴别诊断的价值。方法观察分析213例经病理证实的乳腺肿块的多普勒血流特征,分析血流分级与PSV和RI的相关性。结果乳腺病变血流分级与RI和PSV无明显相关性;血流分级、RI与乳腺病变的良恶性有相关性。结论乳腺病变血流分级越高、RI值越大,病变恶性程度的可能性越大。     

彩色多普勒超声诊断乳腺良恶性肿瘤的价值探讨

目的探讨运用彩色多普勒超声检查乳腺良恶性肿瘤的临床价值。方法收集我院2013年7月至2015年7月乳腺肿瘤80例,所有患者进行彩色多普勒超声检查,同时结合其手术病理资料进行回顾性分析和总结。结果 80例患者均经手术病理证实,其中良性病变者64例,超声检出62例,检出率97%;恶性病变者16例,超声检出15例,检出率占94%。对比良性与恶性肿瘤的超声特征,提示良性肿瘤的边界相对清晰,形态相对规则,内部回声相对均匀,纵横比相对也更小,差异有统计学意义(P<0.05)。良性肿瘤的动脉阻力指数(RI)<0.7者占88%,与恶性肿瘤的12%相比明显更高,差异有统计学意义(P<0.05)。结论尽早对乳腺肿瘤患者实施彩色多普勒超声检查,对于准确鉴别肿瘤的良恶性并指导临床治疗十分关键,应加强推广。     

彩色多普勒检测老年高血压患者肠系膜下动脉的意义

目的:探讨高血压对老年患者肠系膜下动脉(IMA)的血流参数的影响。材料和方法:应用彩色多普勒测定58例老年高血压患者(高血压组)和50例正常老年人(正常组)的肠系膜下动脉内径(D),收缩期峰值速度(PSV)、舒张末期流速(EDV)、阻力指数(RI),搏动指数(PI)。结果:老年高血压患者IMA的内径较正常组增宽,峰值流速、阻力指数增高,舒张期血流流速减,搏动指数变化不明显。结论:老年高血压患者IMA血流动力学较正常老年人有显著变化。     

乳腺肿块的高频彩超诊断与病理对照分析

 目的 探讨高频彩超在鉴别乳腺良、恶性肿块中的价值.方法 对经病理证实的乳腺良、恶性肿块86例的高频彩超进行回顾性分析.结果 高频彩超检查乳腺肿块86例,良性61例,超声检出57例,恶性肿块25例,超声检出23例.以RI =0.7为标准,诊断乳腺癌的敏感性0.92,特异性0.966,准确性0.930.彩色多普勒的阻力指数(RI)、脉动指数(PI)在良、恶性肿块中均有统计学差异(P＜0.01).彩超根据肿块彩色血流丰富程度分4级,良性肿块0、Ⅰ级为主,恶性肿块Ⅱ、Ⅲ级为主,二者有统计学差异(P＜0.01).结论 高频彩超对乳腺性肿块的检出率高,应用二维声像图特点与彩色多普勒分析,综合判断,可明显提高对乳腺良、恶性肿块的诊断水平.     

经阴道彩色多普勒超声诊断卵巢良恶性肿瘤的价值

目的:探讨经阴道彩色多普勒超声对卵巢良、恶性肿瘤的诊断价值及其与临床分期的关系。材料和方法:对47例卵巢恶性肿瘤,18例良性肿瘤,5例交界性肿瘤患者术前行经阴道彩色多普勒超声检查。分析瘤内血管分布类型、瘤内动脉血流参数及动脉频谱舒张期切迹等指标与良、恶性肿瘤及临床分期的关系。结果:卵巢恶性肿瘤动脉血流RI值明显低于良性组,且Ⅲ、Ⅳ期RI值明显低于Ⅰ、Ⅱ期。恶性组血管分布多为Ⅲ型,占38/47,良性组血管分布Ⅲ型为1/18,以血管分布Ⅲ型为标准诊断卵巢恶性肿瘤敏感性80.8%,特异性86.9%。恶性组4/47动脉频谱有舒张期切迹,良性组14/18动脉频谱有舒张期切迹,两组比较差异有统计学意义。结论:RI、血管分布类型、脉冲频谱舒张期切迹是鉴别卵巢良、恶性肿瘤的重要指标,对评价预后有一定的参考价值。     

Computer-assisted quantitative assessment of power Doppler US: effects of microbubble contrast agent in the differentiation of breast tumors

RATIONALE AND OBJECTIVES: To objectively quantify the effects of a microbubble contrast agent to differentiate breast tumors with power doppler ultrasound and to compare these results with color doppler ultrasound (CD US). METHODS: In 47 patients a microbubble contrast agent was injected intravenously. Computer-assisted quantitative assessment of the color pixel density was performed to evaluate the increase in Doppler signals. Results were compared to previously published results of a color Doppler ultrasound study. RESULTS: Peak color pixel density at contrast-enhanced power Doppler ultrasound was higher for carcinomas than for benign tumors (P < 0.03). Time to peak enhancement was shorter in carcinomas than in benign tumors (P < 0.01). For both parameters, diagnostic accuracy of power Doppler ultrasound was 69 and 78%, and for color Doppler ultrasound 62 and 76%, respectively. CONCLUSIONS: Quantitative assessment of contrast-enhanced power Doppler ultrasound showed significant differences in malignant and benign breast tumors. Diagnostic accuracy of contrast-enhanced power Doppler ultrasound was higher compared to color Doppler ultrasound.     

二维及彩色多普勒超声诊断乳腺包块的临床价值

目的：探讨二维及彩色多普勒超声诊断乳腺包块的临床价值。方法应用高频探头对85例各种原因引起的乳腺包块进行检查,所有病例均经手术及病理证实,并与超声诊断对照分析。结果85例乳腺包块经病理证实良性者32例,二维＋多普勒超声准确诊断30例,诊断符合率为93．8％;恶性者53例,二维＋多普勒超声准确诊断50例,诊断符合率为94．3％,且无论良性或恶性,二维＋多普勒超声诊断符合率均较单纯二维声像图诊断率高。结论二维声像图结合彩色多普勒检查可大大提高诊断的正确率,对乳腺疾病的早期发现及良恶性鉴别具有重要意义。     

The ultrasound aspect of the skin and subcutaneous fat layer in various benign and malignant breast conditions.

In a series of 260 consecutive X-ray mammography examinations in symptomatic patients, 25 patients proved to have breast cancer, and 41 had various benign breast conditions. In the 66 patients with abnormal mammograms a real-time ultrasound examination with a 7.5 MHz linear array transducer and a fluid offset pad was performed. This paper focuses on the ultrasound aspect of the skin and the subcutaneous fat layer in various benign and malignant breast conditions. In most of the malignant tumors studied as well as in cases of fat necrosis and breast abscesses, the following ultrasound signs were encountered: discontinuity of the sharp echogenic subcutaneous specular reflector, thickening of the skin, and locally increased echogenicity of the subcutaneous fat layer. In breast cancer these signs were seen in some patients with small tumors, in deeply located tumors as well as in patients with no skin retraction on clinical examination. The differential diagnosis between cancer and benign breast tumors cannot be based upon the ultrasound aspect of the skin and subcutaneous fat layer alone. X-ray mammography as well as clinical criteria and anamnestic factors should be used for the diagnosis of breast abscesses (calor, rubor, tumor, dolor) and for the diagnosis of fat necrosis (surgery, trauma).     

彩超应用在乳腺良恶性肿瘤鉴别诊断中的有效性分析

目的：对彩超应用于乳腺良恶性肿瘤鉴别诊断中的有效性进行分析，并加以总结。方法选择2014年3月～2016年3月诊治的乳腺肿瘤患者66例，使用高频彩超对其进行检查，并与病理确诊结果相比较，判断诊断效果的优良。结果良、恶性肿瘤的检出率分别为87．50％、95．24％，诊断符合率分别为83．33％、90．48％，87．88％，总诊断符合率为87．88％。结论高频彩超在乳腺良恶性肿瘤鉴别诊断中的应用，能够较有效地检出乳腺肿瘤的良性与恶性，与病理结果极为接近，诊断符合率高，具有重大的临床意义，值得应用和推广。     

Value of high frequency (20mhZ) and doppler ultrasound in the diagnosis of pigmented cutaneous tumors]

PURPOSE: Diagnosis of pigmented skin tumors is often difficult. The aim of the present study is to evaluate high frequency ultrasound and Doppler ultrasound in the localization and the characterization of these tumors. MATERIAL AND METHODS: One hundred and seventy six pigmented skin tumors including melanocytic and non melanocytic, benign and malignant lesions have been examined before resection using high frequency ultrasound (20MHz probe) and Doppler ultrasound (13MHz probe-Doppler frequency: 7MHz). Imaging data have been correlated with histological data, available in all cases. RESULTS: Tumors seen at ultrasound were hypoechoic lesions, some of which, particularly malignant melanocytic tumors were vascularized. Precise ultrasonographic location of the tumor was correlated to its histological location: epidermis for purely epidermal proliferations (seborrheic keratoses), superficial dermis for dermal proliferations originating from epidermis (benign dermal nevi, melanomas during vertical growth phase, basal cell carcinomas), middle and deep dermis for dermal proliferations originating from dermis (fibrous histiocytomas, angiomas). CONCLUSION: Ultrasound may help in assessing positive and differential diagnosis of pigmented skin tumors as it precises, before histological examination, the exact location of the lesion within the different skin layers and its origin. As far as malignant melanocytic tumors are concerned, high frequency ultrasound and Doppler ultrasound appear promising in diagnosis algorithm and pronosic of these lesions.     

肿块深度对乳腺超声弹性成像检查结果的影响分析

目的 探究超声弹性成像(UE)中肿瘤深度对于判断乳腺肿物的良、恶性影响.方法 选取本院2017年1月～2018年10月间收治的178例因乳腺肿块行手术切除患者为观察对象,纳入病灶200个.依据肿瘤深度不同分4组.对所有的患者在术前均予以常规超声检查以及超声弹性成像检查,对比不同深度肿瘤的UE成像情况、分析诊断效能(准确...     

彩色多普勒超声和多层螺旋CT在肾脏良恶性肿瘤诊断中的应用比较简

目的：比较彩色多普勒超声（US）和多层螺旋CT（MSCT）在诊断肾脏良恶性肿瘤中的临床应用价值。方法对35例肾肿瘤患者分别行超声和螺旋CT检查,将两者检查结果与手术后病理结果进行对比,比较两种检查方法的诊断准确率。结果肾良性肿瘤及病变25例,超声诊断准确率为84％,CT为88％;肾癌10例,超声诊断准确率为80％,CT检查为90％。结论 US和MSCT在诊断肾脏良恶性肿瘤中,超声是筛查肾脏肿瘤首选检查方法,其价格低廉,无电离辐射,简单易行,患者容易接受。MSCT检查在特异性和准确性方面要高于超声,但在敏感性方面超声要优于CT,两者都能较准确地判断肾脏肿瘤及病变的良恶性。     

彩色多普勒超声与MR诊断乳腺病变的临床价值分析

目的：比较彩色多普勒超声、磁共振动态增强对乳腺病变的临床诊断价值。方法收集经手术与病理证实的95例同时做过超声与M R的101个乳腺病灶,对其二维声像图及CDFI特点与磁共振动态增强影像学表现,对照病理结果进行回顾性分析。结果彩色多普勒与MR动态增强扫描对乳腺良恶性病变定性诊断准确率分别为：超声良性病变诊断正确率73．3％,恶性病灶诊断正确率87．3％;M R良性病变诊断正确率84．3％,恶性病灶诊断正确率92．7％。95个患者共检出101处病灶,其中乳腺癌67例,占66％;纤维瘤23例,占23％,炎性肉芽肿4例,占4％;分叶状肿瘤2例,占2％;囊腺瘤1例,占1％;乳头状瘤4例,占4％。结论超声检查诊断准确性高,适用于乳腺疾病的常规检查;MR空间分辨力及软组织分辨力高,适用于超声检查难以定性的病变及乳腺癌的术前评估。     

高频超声检测乳腺癌与乳腺纤维腺瘤诊断价值的探讨

目的:探讨高频超声和彩色多普勒(CDFI)对乳腺良、恶性肿瘤的形态及血流动力学特点,对鉴别良、恶性肿瘤的诊断价值。方法:应用高频超声结合CDFI技术对146例乳腺肿瘤的声像图特征及血流动力学与病理结果对照分析。结果:146例乳腺肿瘤中,乳腺纤维腺瘤90例,符合率94.4%,浸润性导管癌56例,符合率91.1%。结论:乳腺癌的特征性表现为形态不规则,毛刺状或蟹爪状,致密小钙化灶和后方回声衰减,CDFI:RI>0.75。乳腺纤维腺瘤的特征性表现为边界清晰,形态规则,有包膜和侧边声影,CDFI:RI<0.75。但是部分良、恶性肿瘤有交叉表现。