扩髓与非扩髓髓内钉固定治疗胫骨闭合性骨折的系统评价

[目的]系统评价扩髓髓内钉(reamed intramedullary nailing,RTN)与非扩髓髓内钉(unreamed intr-amedullary nailing,UTN)治疗胫骨闭合性骨折的疗效。[方法]通过计算机检索、手工检索和其他检索方法,收集RTN与UTN治疗胫骨闭合性骨折的随机对照试验(randomized controlled trials,RCT)和半随机对照试验(quasi-ran-domized controlled trials,CCT),按Cochrane协作网推荐的方法进行系统评价。[结果]共纳入6个RCT研究,总病例数为1214例。Meta分析显示:(1)RTN组的骨折不愈合率低于UTN组,差异有统计学意义(RR=0.41;95%CI(0.21,0.78),P=0.007);(2)RTN组的内置物失败率低于UTN组,差异有统计学意义(RR=0.32;95%CI(0.20,0.50),P<0.000 1);(3)RTN组与UTN组术后畸形愈合率及感染率差异无统计学意义,两者相对危险度分别为0.45(95%CI(0.16,1.22),P=0.12)、0.45(95%CI(0...     

保守治疗和切开复位钢板内固定治疗锁骨中段骨折的荟萃分析

[目的]通过荟萃分析比较保守治疗和切开复位钢板内固定治疗锁骨中段骨折的临床疗效。[方法]计算机检索2000年1月～2018年10月PubMed、The Cochrane Library、EMbase、MEDLINE(Ovid)、CBM、CNKI和万方医学数据库,搜索保守与切开复位钢板内固定治疗成人锁骨中段骨折的随机对照试验,严格按照纳入和排除标准及文献质量评分标准收集数据,采用RevMan 5.3统计学软件对所提取的文献数据进行荟萃分析。[结果]共纳入9篇文献,共计1 111例患者。荟萃分析显示:锁骨中段骨折的两种治疗方案在术后1年的DASH无明显差别[MD=3.58,95%CI(-0.49,7.65),P=0.08],但钢板内固定组在术后1年的Constant评分略有优势[MD=-3.53,95%CI(-6.92,-0.15),P=0.04];此外,钢板内固定可使骨不连[RR=8.51,95%CI(4.50,16.07),P0.001]及二次手术[RR=3.22,95%CI(2.12,4.90),P0.001]发生率显著降低。[结论]目前证据显示,切开复位钢板内固定治疗锁骨中段骨折术后1年的功能优于保守治疗,并明显降低骨不连及二次手术发生率。     

手术与非手术治疗新鲜无移位舟骨腰部骨折的Meta分析

[目的]系统评价新鲜无移位舟骨腰部骨折手术与非手术治疗的效果。[方法]计算机检索MEDLINE、EMBASE、PubMed、SpringerLi、Cochrane Library、中国生物医学文献数据库、中国知网、国家科技图书文献中心等数据库(1982年1月²012年5月),手工检索相关杂志,制定纳入排除标准,收集相关的随机对照试验(random contrast trial,RCT),对纳入的研究进行方法学质量评价和资料提取后,采用RevMans.5软件进行Meta分析。[结果]共9篇RCT研究类型的论文纳入本研究,共计501例患者,Meta分析显示手术组患者的骨折愈合时间、重返工作时间较石膏组患者短(P<0.000 1),骨折不愈合率比石膏组患者(P=0.00 2)低,手术组患者腕关节活动度、握力恢复较石膏组患者差(P<0.000 01),手术组患者的并发症与石膏组患者相比无明显差别(P=0.74)。[结论]手术治疗急性舟骨骨折与保守治疗相比较分别有各自的优势,应综合考虑患者客观情况和主观愿望决定采用何种治疗:对于急于重返工作或生活中难以长期维持外固定的患者则可首先考虑手术治疗。     

锁骨中段骨折手术治疗与非手术治疗的比较

3项小样本的随机对照研究和1项回顾性队列研究对锁骨中段骨折的手术治疗与非手术治疗进行了比较,结果提示手术治疗疗效更优,其中手术治疗患者的骨折愈合率更高、愈合时间更短.另外,功能评分结果提示手术治疗后患者恢复更好,而且术后患者对肩部外观和总体情况的满意度也明显高于非手术组.手术治疗后可能出现的并发症包括伤口或钉道感染、切口麻木、骨折区疼痛及内固定材料的相关问题等,但是非手术治疗后的并发症可能更严重,如骨折延迟愈合或不愈合、骨折区疼痛等.因此,应进一步开展随机对照研究,明确何种术式更有利于锁骨中段骨折的治疗.     

锁骨中段移位骨折的手术治疗与非手术治疗比较

[目的]比较非手术治疗与切开复位钢板固定治疗锁骨中段移位骨折的疗效。[方法]对2001年3月到2005年12月收治110例单侧锁骨中段完全移位骨折的随访资料进行回顾分析。手术组62例，采用切开复位钢板螺钉固定，男53例，女9例，年龄21—51岁，平均33．5岁。非手术组48例，采用手法复位“8”字绷带固定，男33例，女15例，年龄19～50岁，平均33岁。110例患者在治疗后6周、3、6、12个月，对其临床表现、肩关节评分、并发症发生情况及X线表现进行评价。[结果]全部病例随访1年，肩关节评分在随访各时相点手术组要比非手术组高，有显著差异（P〈0．01）。平均骨愈合时间手术组为16．4周而非手术组为28．4周，有显著差异（P〈0．01）。非手术组有7例骨不愈合及9例骨畸形愈合，比手术组高，差异有显著性（P〈0．05，P〈0．01）。其他与钢板有关并发症两组间无明显差异。[结论]切开复位钢板固定治疗锁骨中段移位骨折是安全有效的，减少骨折畸形愈合、骨不愈合的发生，可使肩关节功能早日恢复。     

肱骨干骨折手术与非手术治疗的荟萃分析

[目的]评价手术与非手术治疗肱骨干骨折的临床疗效。[方法]检索自建库至2021年1月Pubmed, Embase, The Cochrane library, Web of science, SinoMed,中国知网,万方,维普等数据库关于非手术治疗与手术治疗肱骨干骨折疗效比较的文献,依据纳入与排除标准进行文献的筛选和资料提取,采用Revman 5.4软件对各项结局指标和并发症进行荟萃分析。[结果]共纳入18篇文献,其中随机对照研究4篇。共包括2 218例患者,其中手术组1 278例,非手术组940例。荟萃分析显示:非手术治疗组的骨不连率、再次手术率、骨折畸形愈合率和CMS评分均高于手术治疗组(P0.05),继发性桡神经损伤率和感染发生率低于手术治疗组,差异有统计学意义(P0.05),而延迟愈合率、骨折愈合时间、DASH评分、Mayo肘关节功能评分两组差异无统计学意义(P0.05)。[结论]非手术治疗与手术治疗肱骨干骨折临床疗效相似,非手术治疗骨不连的发生率更高,但手术治疗后出现继发性桡神经损伤明显增多。     

3D打印辅助手术与传统手术治疗Pilon骨折疗效比较的荟萃分析

[目的]系统评价3D打印辅助手术和传统手术在治疗Pilon骨折中的疗效。[方法]计算机检索PubMed、Embase、Web of Science、CNKI、CBM、WanFang等中外数据库,至2018年5月1日。两位作者分别进行文献搜集、筛选、质量评估、数据提取,存在争议时,通过讨论解决。[结果]共5篇RCTs符合纳入标准,包含319例患者,其中158例患者采用3D打印辅助手术,161例行传统手术。Meta分析结果显示:3D打印辅助手术手术时间[MD=-21.72,95%CI (-28.49,-14.95),P0.05]、失血量[MD=-76.17,95%CI (-103.95,-48.40),P0.05]、术后功能恢复[MD=7.59, 95%CI (2.21,12.97),P0.05]、术后疼痛[MD=-0.59,95%CI (-1.18,-0.01), P0.05]、优良率[RR=1.16,95%CI (1.04,1.29),P0.05]、解剖复位率[RR=1.32,95%CI (1.12,1.55),P0.05]明显优于传统手术方式。在骨折愈合时间[MD=-1.06,95%CI (-2.53,0.41),P0.05]和感染率[RR=0.51,95%CI (0.20,1.31),P0.05]方面,两者无显著差别。[结论] Meta分析结果表明3D打印辅助手术手术时间、失血量、术后功能恢复、术后疼痛、优良率及解剖复位率明显优于传统手术方式。对于复杂的Pilon骨折,我们常规推荐使用3D打印辅助手术。     

手术与非手术治疗老年肱骨近端复杂骨折疗效比较

目的比较手术与非手术治疗老年肱骨近端三、四部分骨折的疗效。方法 2009年1月-2011年1月,收治35例肱骨近端三、四部分骨折老年患者。其中20例行切开复位、锁定钢板内固定治疗(手术组),15例行闭合复位、夹板或石膏外固定(非手术组)。两组患者性别、年龄、病因、骨折分型及病程等一般资料比较,差异均无统计学意义(P>0.05),具有可比性。两组治疗后均行正规功能锻炼。结果手术组患者术后切口均Ⅰ期愈合。两组患者均获随访,随访时间12～20个月,平均16个月。X线片检查示,除手术组1例(5.0%)骨折不愈合,其余患者骨折均愈合。手术组2例(10.0%)、非手术组1例(6.7%)发生内翻畸形,手术组1例(5.0%)、非手术组1例(6.7%)发生肱骨头缺血性坏死。两组以上并发症发生率比较,差异均无统计学意义(P>0.05)。末次随访时,手术组与非手术组肩关节功能Constant-Murley评分分别为(66.8±11.8)分及(64.7±9.9)分,比较差异无统计学意义(t=0.59,P=0.47)。结论手术与非手术治疗老年肱骨近端三、四部分骨折疗效相似,对手术风险高、日常活动要求低或拒绝手术治疗的老年患者可选择非手术治疗。     

手术干预与传统方法治疗多发性肋骨骨折随机对照研究的系统评价与Meta分析

目的对手术和传统方法治疗多发性肋骨骨折进行系统评价,对比其疗效。方法计算机检索中国期刊全文数据库(CNKI)、万方数据库(Wanfang)、维普期刊数据库(VIP)、PubMed、OVID、EMbase、The Cochrane Library、Thieme及Springer Link数据库。收集有关手术和传统方法治疗多发性肋骨骨折的随机对照研究(RCT),检索时限为各数据库建库至2019年7月。对文献进行筛选、质量评价及数据提取。Meta分析采用RevMan 5.3软件。结果共纳入文献12篇,患者1039例。其中手术组512例,传统组527例。Meta分析显示:两组在肺部感染发生率[RR=0.41,99%CI(0.29,0.58),P<0.00001]、肺不张发生率[RR=0.24,99%CI(0.06,0.94),P=0.007]、呼吸机支持时间[SMD=-2.64,99%CI(-4.38,-0.91),P<0.0001]、住ICU时间[SMD=-1.33,99%CI(-2.26,-0.40),P=0.0002]、总体住院时间[SMD=-2.25,99%CI(-3.30,-1.19),P<0.00001]、胸壁畸形发生率[RR=0.08,99%CI(0.04,0.17),P<0.00001]等方面差异有统计学意义。在住院死亡率[RR=0.75,99%CI(0.23,2.46),P=0.53]、气管切开率[RR=0.69,99%CI(0.39,1.21),P=0.09]、呼吸机支持率[RR=0.65,99%CI(0.41,1.05),P=0.02]、胸腔引流时间[SMD=-2.58,99%CI(-6.41,1.25),P=0.08]等方面差异无统计学意义。结论手术治疗多发性肋骨骨折能够减少肺部并发症、缩短住院时间、降低胸壁畸形发生率,有利于患者快速康复和改善生活质量。     

Kümmell病的临床治疗进展

目的:系统评价自体骨移植与骨形成蛋白治疗成人长骨骨折不愈合相关指标,为成人长骨骨折不愈合治疗提供参考依据。方法:计算机检索PuMed、Embase、Cochrane图书馆、中国知网(CNKI)、万方数据期刊全文数据库及中国生物医学文献数据库(CBM)发表的对于自体骨移植与骨形成蛋白治疗成人长骨骨折不愈合的随机对照试验,检索时间从建库至2019年3月。由2名研究者按照纳入和排除标准独立进行筛选文献,提取资料,并采用Jadad评价量表对纳入的文献进行质量评价。采用RevMan 5.3统计学软件对两种方法的感染发生率、成功愈合率、二次手术率、住院时间及术中失血量进行Meta分析。结果:共纳入7个随机对照试验研究,共652例患者,自体骨移植组有410例,骨形成蛋白组有242例。Meta分析结果显示:自体骨移植组与骨形成蛋白组在感染发生率[RR=1.32,95%CI(0.90,1.93),P=0.16],成功愈合率[RR=0.95,95%CI(0.84,1.08),P=0.43],二次手术率[RR=1.16,95%CI(0.43,3.12),P=0.76]及住院时间[MD=0.69,95%CI(-0.38,1.75),P=0.21]方面比较差异无统计学意义。自体骨移植组术中失血量明显高于骨形成蛋白组[MD=223.00,95%CI(32.72,413.28),P=0.02]。结论:对于成人长骨骨折不愈合的治疗,骨形成蛋白可以获得和自体骨移植一样的骨折愈合率,同时可以明显减少术中失血量。骨形成蛋白可能更适合成人长骨骨折不愈合的治疗。     

Intramedullary Nailing Versus Minimally Invasive Plate Osteosynthesis for Distal Tibial Fractures: A Systematic Review and Meta‐Analysis

To evaluate the application, safety and efficacy of the patients treated with intramedullary nailing (IMN) and minimally invasive plate osteosynthesis (MIPO) in distal tibia fractures. Following the Preferred Reporting Items for Systematic Reviews and Meta Analysis (PRISMA) guidelines, we searched databases PubMed, Cochrane library, EMBASE and Web of Science from inception of the database up to 10 October 2018, using the keywords “distal tibia fractures”, “plate”, “intramedullary nailing” and “RCT” to identify randomized clinical trials about distal tibia fractures. The included studies were assessed by two researchers according to the Cochrane risk‐of‐bias criteria. The primary outcome of measurement included operation time, malunion rate, nonunion/delayed union rate, and wound complication. Data analysis was conducted with Review Manager 5.3 software. A total of 10 RCTs involving 911 patients fulfilled the inclusion criteria with 455 patients in the IMN group and 456 patients in the MIPO group. There were no significant differences in radiation time, nonunion or delayed union rate, union time and operation time between the two groups. Patients treated with MIPO had lower incidence of malunion compared with IMN (RR = 1.85, 95%CI: 1.21 to 2.83, P = 1.00), while IMN seemed to have lower surgical incision complications whether in closed or opening fractures (RR = 0.49, 95%CI 0.33 to 0.73, P = 0.43). But in patients classified as 43A, the result of subgroup analysis suggested that there was no significant inwound complication between the two groups. MIPO was superior in preventing malunion compared with IMN, and intramedullary nailing appeared to have lower wound complications. However, in patients with 43A distal tibial fractures, MIPO was more recommended for its prevention of malunion. No matter which method we choose, we should notice and prevent the associated complications.     

成人锁骨中段骨折手术治疗与非手术治疗的Meta分析

目的 应用Meta分析系统总结评价手术治疗与非手术治疗在成人锁骨中段骨折中的疗效及相关优势.方法 通过检索1989至2009年间Cochrane Database、Pub med & Ovid Medline、OTA、AAOS、High Wire Press、Springer Link、中国生物医学文献数据库、中国知网和万方数据库,并且配合手工检索相关领域的杂志,纳入以成人锁骨中段骨折为研究对象,比较手术治疗与非手术治疗的随机对照实验及回顾性队列研究,评价纳入研究质量,并用Rvaman 4.2进行Meta分析.结果 经过筛选初检文献5053篇,共纳入8个研究(519例患者).共有5个研究选用骨折愈合率作为观察指标,结果P＜0.00001;4个研究选用畸形愈合率作为观察指标,结果P＜0.0001;5个研究选用神经刺激症状作为观察指标,结果P＜0.0001;4个研究选用患者满意度作为观察指标,结果P＜0.00001;4个研究选用残余痛作为观察指标,结果P=0.56;2个研究选用关节活动障碍作为观察指标,结果P=0.25;3个研究选用再骨折作为观察指标,研究不存在异质性,结果P＞0.05.结论 系统评价的结果表明,手术治疗成人锁骨中段骨折较非手术治疗存在优势.

Abstract：

Objective To systematically summarize and compare results and related advantages of different methods in the management of adult mid-shaft clavicle fractures. Methods The data of adult midshaft clavicle fracture from 1989 to 2009 was retrieved. The database were included Cochrane Database,med & Ovid Medline, OTA, AAOS, High Wire Press, Springer Link, CBM, CNKI, WANFANG DATA and with hand-search journals in related fields. Internalizing randomized controlled trials and retrospective cohort studies which compared the operative and nonoperative treatment for adult mid-shaft clavicle fracture. Evaluating the quality of included studies and using the Rvaman 4.2 for Meta-Analysis. Results 5053 literatures had been reviewed. After screening, there were 8 studies brought into the review that included 519 patients.There were 5 studies which took union rate as observed indicator. The results had statistically significant (P＜0.00001). A total of 4 studies used malunion rate as indicator, the results had statistically significant (P ＜0.0001). A total of 4 researches selected satisfaction of patient as indicator, the results had statistically significant(P＜0.00001). A total of 5 studies selected symptoms of nerve stimulation as indicator, the results had statistically significant (P＜0.0001). A total of 4 studies selected residual pain as indicator, the results had no significant statistically difference (P=0.56). A total of 2 studies selected barriers of joint activities as indicator, the results had no significant statistically difference (P=0.25). A total of 2 researches used refracture as indicator, the results had no significant statistically difference (P＞O.05). Conclusion This study evaluation results shows that operation can be used as the first choice of treatment of adult midshaft clavicle fractures.     

Surgical versus conservative management of ankle fractures in adults: A systematic review and meta-analysis

AimsThis study compared outcomes of surgical versus conservative management of ankle fractures in adults through a systematic review and meta-analysis.MethodsWe searched CINAHL, EMBASE, MEDLINE and CENTRAL databases (1946–June 2019) for randomised and quasi-randomised controlled trials comparing surgical versus conservative management of closed adult ankle fractures of any type. Estimates of effect were pooled using random effects meta-analysis.Results1153 patients from 7 trials were included. Our primary outcome, ankle function score, was not statistically significantly different at 6-months (pooled mean difference (surgical minus conservative) = 1.0; 95% CI: −2.3 to 4.3; p = 0.55) or 12-months or more (pooled mean difference = 4.6; 95% CI: −1.0 to 10.2; p = 0.11) between surgical and conservative groups in three trials assessing displaced or unstable fractures, and two trials using non-validated questionnaires. One trial assessing AO-type-B1 fractures without talar shift had a statistically significant difference favouring conservative management, which was not clinically meaningful. Surgery had lower rates of early treatment failure and malunion/non-union, but higher rates of further surgery and infection.ConclusionsSurgical and conservative management of displaced or unstable ankle fractures produce similar short-term functional outcomes. The higher risk of early treatment failure and malunion/non-union in the conservative group versus higher rates of further surgery and infection in the surgical group should be considered. Trials are needed to assess longer-term results and inform management of select patient groups.     

单孔与多孔腹腔镜胆囊切除术的安全性Meta分析

目的系统评价经脐单孔腹腔镜胆囊切除术(SILC)与传统多孔腹腔镜胆囊切除术(CMLC)的有效性和安全性。 方法计算机检索CBM、CNKI、PubMed、EMbase、The Cochrane Library数据库,筛选截至2015年7月关于比较SILC与CMLC的随机对照试验(RCT),采用RevMan 5.3软件进行Meta分析。 结果本研究共纳入34篇RCT文献,合计2 951例患者(SICL组1 502例,CMLC组1 449例)。SILC组的手术时间长于CMLC组,差异有统计学意义[MD＝11.56,95%CI(8.97,14.16),Z＝8.75,P<0.000 01]。相比CMLC组,SILC组的手术转换率更高,差异有统计学意义[RR＝4.01,95%CI(2.56,6.29),Z＝6.06,P<0.000 01]。SILC组患者切口美容评分高于CMLC组,差异有统计学意义[SMD＝1.34,95%CI(0.74,1.94),Z＝4.39,P<0.000 1]。两组术中出血量、术后并发症、术后24 h疼痛评分、住院时间及恢复工作时间比较,差异无统计学意义(P>0.05)。 结论SILC是一项安全有效的手术操作方式,具有更好的美容效果,但手术时间长、术中转换率高,对术者经验和手术技巧要求更高,需综合考虑选择。     

ORIF versus MIPO for humeral shaft fractures: a meta-analysis and systematic review of randomized clinical trials and observational studies

BackgroundThere is no consensus on the optimal operative technique for humeral shaft fractures. This meta-analysis aims to compare minimal-invasive plate osteosynthesis (MIPO) with open reduction internal fixation (ORIF) for humeral shaft fractures regarding non-union, re-intervention, radial nerve palsy, time to union, operation duration and functional outcomes.MethodsPubMed/Medline/Embase/CENTRAL/CINAHL were searched for both randomized clinical trials (RCT) and observational studies comparing MIPO with ORIF for humeral shaft fractures. Effect estimates were pooled across studies using random effects models and presented as weighted odds ratio (OR), risk difference (RD), mean difference (MD) and standardized mean difference (SMD) with corresponding 95% confidence interval (95%CI). Subgroup analysis was performed stratified by study design (RCTs and observational studies).ResultsA total of two RCT's (98 patients) and seven observational studies (263 patients) were included. The effect estimates obtained from observational studies and RCT's were similar in direction and magnitude. MIPO carries a lower risk for non-union (RD: 5%; OR 0.3, 95% CI 0.1-0.9) and secondary radial nerve palsy (RD 5%; OR 0.3, 95%CI 0.1- 0.9). Nerve function eventually restored spontaneously in all patients in both groups. Results were inconclusive regarding re-intervention (RD 7%; OR: 0.7, 95%CI 0.2-1.9), infection (RD 4%; OR 0.4, 95%CI 0.1-1.5), time to union (MD -1 week, 95%CI -3 – 1) and operation duration (MD -13 minutes, 95%CI -38.9 – 11.9). Functional shoulder scores (SMD 0.01, 95%CI -0.3 – 0.3) and elbow scores (SMD 0.01, 95%CI -0.3 – 0.3) were similar for the different operative techniques.ConclusionMIPO has a lower risk for non-union than ORIF for the treatment of humeral shaft fractures. Radial nerve palsy secondary to operation is a temporary issue resolving in all patients in both treatment groups. Although both treatment options are viable, the general balance leans towards MIPO having more favorable outcomes.     

后尿道损伤不同术式处理后尿道狭窄发生率的Meta分析

目的 比较早期尿道会师加牵引术(即早期复位术)及早期耻骨上膀胱造瘘加延期尿道吻合术(即延期尿道成形术)处理骨盆骨折致后尿道损伤的疗效.方法 收集1966年至2006年Medline、荷兰医学文摘、中国生物医学文摘、Cochrane图书馆临床对照试验资料库与骨盆骨折导致后尿道损伤处理的有关文献,由2位评价者按相关限定条件进行筛选,选出符合纳入标准文献,使用RevMan 4.2软件进行Meta分析.结果 共10篇文献470例患者资料纳入分析,其中采用早期复位术249例、延期成形术221例.2种术式术后尿道狭窄发生率比较,OR一0.27,95%CI 0.08～0.86,P=0.03,差异有统计学意义;早期复位术术后狭窄需要再次行尿道吻合术者低于延期成形术,OR=0.25,95%,CI 0.08～0.74,P=0.01,差异有统计学意义.结论 早期复位术术后尿道狭窄的发生率低,治疗容易.本Meta分析不能排除分组时产生的偏倚,如尿道损伤的严重程度.     

腹腔镜与开腹大范围肝切除治疗肝脏肿瘤的荟萃分析

目的:采用荟萃分析比较腹腔镜与开腹大范围肝切除治疗肝脏肿瘤的近期疗效及安全性。方法:大范围肝切除术是≥3个肝段的肝切除手术。计算机检索至2014年6月的Pub Med、EMbase、Cochrane、CBM、CNKI、万方、维普数据库相关文献,收集并比较两种方式治疗肝脏肿瘤的临床对照研究。采用Rev Man5.2软件对数据行荟萃分析。结果:未获得随机对照试验,纳入7项临床同期对照试验,共863例(腹腔镜组275例,开腹组588例)。荟萃分析结果显示:腹腔镜大范围肝切除术中出血量[加权均数差(weight mean difference,WMD)为-158.38 m L,95%CI:-233.81~-82.96,P     

Comparison of plate osteosynthesis versus non-operative management for mid-shaft clavicle fractures—A prospective study

IntroductionTreatment for mid-shaft clavicle fractures has recently seen a paradigm shift towards surgical management. The aim of the study was to compare clinical and functional outcome between plate osteosynthesis and conservative line of management in middle-third clavicle fractures.Material and methodsA prospective randomized study was conducted on 69 patients with closed displaced clavicle fractures between May 2014 and May 2016. Patients with medial or lateral third clavicle fractures, polytrauma and compound fractures were excluded from the study. Patients treated with plating were in group A (n = 36) while those treated with arm pouch were in group B (n = 33).ResultsThe mean age of the patient in group A was 32.4 ± 43 and group B was 31.7 ± 26 years. 48 (69.9%) females were involved in the study. History of fall was the most common mechanism of injury affecting 51 (73.9%) patients. All the patients were type 2 B as per the Robinson classification system. The average operative duration was 78.3 ± 12.4 min. Union was seen at 15.6 ± 0.8 in group A and 22.8 ± 0.4 in group B (p < 0.0001). Two (6%) of the patients in group B had non-union. One (2.7%) patient in group A had mal-union. Two (5.5%) patients had plate prominence. One (2.7%) patient had superficial infection. The Constant and Murley scoring at 24 months was 89.42 and 76.24 in group A and group B respectively.ConclusionPlating for displaced mid-shaft clavicle fractures is can lead to better functional and radiological outcomes with minimal complications as compared to the conservative modality of treatment.     

锁定钢板与半肩关节置换治疗中老年复杂肱骨近端骨折的Meta分析

目的通过Meta分析探讨锁定钢板(LP)及半肩关节置换(HA)治疗肱骨近端骨折(PHFs)术后并发症及疗效的差异。 方法计算机检索Pubmed、Cochrane图书馆、EMBASE、ScienceDirect、中国知网、万方、维普等数据库。搜集有关LP/HA治疗PHFs的各种对照研究,纳入标准：随机或非随机对照试验;行LP和HA治疗;年龄≥ 45岁;随访时间>3个月;可提取到可靠的数据。排除标准：病例数少于10例;其他治疗方式;病例报告,综述,动物实验以及系统评价;多种原因不能耐受手术;病理性骨折或者肱骨近端陈旧性骨折;既往有肩关节外伤及手术病史。研究共纳入27项研究2 082例患者,对纳入的文献选择总并发症、常见并发症(肩关节不稳、关节僵硬、肩峰下撞击症)、术后功能评分(Constant-Murley肩关节评分系统、美国肩肘外科医师协会评分)作为Meta分析的评价指标,采用STATA 14.0分析,对于合并SMD 或者OR ,P <0.05差异有统计学意义。 结果结果表明两组总并发症[OR ＝1.73,95%CI(1.35,2.21),P <0.01]、肩峰下撞击症[OR ＝0.25,95%CI(0.11,0.55),P<0.01]以HA组较低;上肢肌力评分[SMD＝1.857,95%CI(0.803,2.912),P<0.01]、肩关节活动度评分[SMD＝2.542,95%CI(1.273,3.811),P<0.01]以LP组较优。两组CMS、ASES评分差异无统计学意义(P >0.05)。 结论HA术后并发症的发生率低于LP,两者均能获得相近的肩关节功能恢复。     

������Ƥǻ��Ѫ�ܳ�������֧�������������ж̶ι��N����Ӳ������֢��Ч����ȫ��Meta����

??Simple percutaneous transluminal angioplasty versus primary stent placement in treating short-intermediate superficial femoral-popliteal artery occlusive disease about clinical safety and efficacy??A Meta-analysis SI Xiao-mao*?? ZHA Bin-shan?? XIE Wen-tao??et al. *Department of Vascular Surgery, the First Affiliated Hospital of Anhui Medical University??Hefei 230032, China
Corresponding author: ZHU Hua-gang, E-mail??huagzhu@yeah.net
Abstract Objective To compare the clinical safety and efficacy of primary stent placement (ST) versus simple percutaneous transluminal angioplasty (PTA) in treating superficial femoral-popliteal artery (SFPA) occlusive disease using Meta-analysis method. Methods Prospective randomized controlled trials (RCT??comparing ST and PTA clinical effects published from January 1993 to January 2013 were retrieved. A Meta-analysis was conducted to estimate the immediate operation success rate, postoperative restenosis rate, target vessel revascularization (TVR). Results A total of 9 RCT were included in the analysis, including 948 patients and 971 limbs??489 limbs in ST group and 482 limbs in PTA group. The immediate operation success rate was higher in the ST group and the difference was significant statistically (OR=7.02, 95% CI 3.83-12.86, P<0.001). Postoperative 12 months vascular restenosis rates in ST group were less than those in PTA group with significant difference??OR=0.58??95%CI 0.38-0.89??P=0.01??. The difference of postoperative 24 months vascular restenosis rates between two groups was not significant statistically??OR=0.82??95%CI 0.55-1.24??P=0.35??. There was no difference statistically in target vessel revascularization and vascular complications between two groups (P>0.05). Conclusion For short-intermediate SFPA occlusion lesions (less than 15cm), short-term outcomes of ST is better than the PTA. But there is not enough evidence to prove that long-term outcome (longer than 24 months) of ST group is better than the PTA group.