Pattern of individual biorhythms of the rectal temperature of rats in health and during starvation

Individual cosinor-analysis with the use of special software demonstrates that the rectal temperature of intact rats exhibits two clear-cut rhythms: the circadian rhythm and a 96-h infradian rhythm. Under conditions of total starvation, including a lethal outcome, the spectrum of the biorhythms of the rectal temperature alters markedly: the circadian rhythm is completely eliminated in the majority of starving animals, the amplitude of the 4-day rhythm declines or this rhythm is also eliminated, and ultradian and infradian components appear in the biorhythmic pattern of the rectal temperature. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N ^o 6, pp. 656–657, June, 1994 Presented by Yu. A. Romanov, Member of the Russian Academy of Medical Sciences     

Effect of cerebrocrast on local cerebral bloodflow and EEG of alert rats with brain ischemia

Cerebrocrast, a, 1,4-dihydropyridine derivative, accelerated blood delivery to the brain and normalized the spectrum and total power of the electroencephalogram during brain ischemia; manifestations of interhemispheric asymmetry of the electroencephalogram and cerebral bloodflow were leveled. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, N ^o . 3, pp. 296–298, March, 1995 Presented by E. D. Gol'dberg, Member of the Russian Academy of Medical Sciences     

Assessment of the efficacy of treatment of hemangiomas

Assessment of the aftereffects of cryoexposure and ultrahigh-frequency cryoexposure on hemangioma tissue of various types, cavernous and squamous, showed a higher cryogenic effect in hemangiomatous tissue preexposed to ultrahigh-frequency waves. A quantitative criterion is proposed for assessing the efficacy of the studied methods of exposure. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, N ^o 6, pp. 669–672, June, 1995     

Efficacy of transplantation of human fetal tissues in treatment of the child with Fanconi's syndrome

A fundamentally new method of treating children with Fanconi's syndrome using the transplantation of human fetal tissues is outlined below. A positive dynamics is noted in clinical and laboratory manifestations. This is a preliminary report. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N ^o 4, pp. 392–395, April, 1994     

Reactivity of capillaries and pyramidal neurons in rat cortex under conditions of acutely reduced circulation

A study of capillaries and pyramidal neurons of the cortex in white rats subjected to ligation of the common carotid artery reveals that acute reduction of the circulation is characterized by a decreased activity of alkaline phosphatase and Na, K-ATPase as well as a reduced number of capillaries marked with these enzymes, and a lower activity of butyrylcholine esterase. A decreased activity of cytochrome oxidase in neurons suggests the existence of intracellular compensatory-adaptive mechanisms. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N ^o 5, pp. 558–560, May, 1994 Presented by O. S. Adrianov, Member of the Russian Academy of Medical Sciences     

Effect of thymoptin on the behavior of experimental animals

A study is made of the effect of thymoptin, a preparation containing a complex of acid peptides from the thymus, on the behavior of experimental animals. It is found that in a dose of 400 μg/kg the preparation enhances motor activity, raises the body temperature, augments pain sensitivity, stimulates behavior in the open field test, and facilitates learning and memory processes. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121 N ^o 3, pp. 285–287, March, 1996 Presented by Yu. A. Romanov, Member of the Russian Academy of Medical Sciences     

Cell death and the efficiency of the erythropoietic system

The efficiency of the erythropoietic system is studied with the aid of mathematical modeling under conditions of a high fraction of cell death. A criterion limiting the magnitude of cell death is proposed for possible forms of chronic pathology. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, N ^o 3, pp. 357–358, March, 1996     

Localization and fate of thymic epitheliocytes of endodermal origin synthesizing cytokeratin 18

A reaction in the cytoplasm and processes of some cells of the epithelial reticulum is revealed by indirect immunofluorescence with monoclonal antibodies to cytokeratin 18 in the cortical zone of human thymus. In the medullary zone the reaction is observed in spherical elements similar in shape and size to intestinal goblet cells. Translated fromByulleten' Eksperimental'noi Biologii i Medsitsiny, Vol. 117, N ^o 2, pp. 188–190, February, 1994 Presented by V. I. Shumakov, Member of the Russian Academy of Medical Sciences     

Characteristics of neurons of the nodose ganglion with constant spike activity

Translated fromByulleten Eksperimental'noi Biologii i Meditsiny, Vol. 115, N ^o 3, pp. 236–238, March 1993     

Effects of ultrasound,the polyene antibiotic amphotericin B,and their combination on biomembranes of yeastlikeCandida fungi

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 10, pp. 391–393, October, 1993     

Analysis of changes in the electroencephalogram power spectrum on a new model of brain ischemia in rats

The bioelectrical activity is studied in the left and right parietal cortex by recording the power spectrum of the electroencephalogram in brain ischemia caused by complete ligation of the left common carotid artery and 50% reduction of the blood flow in the right common carotid artery in experiments carried out on nonnarcotized Wistar rats. Ischemia results in marked and stable disorders in the bioelectrical activity manifested in a decrease of the total EEG power, depression of the dominating frequency in the Θ-range, increase of the δ-range power, and interhemispheric asymmetry of some spectrogram parameters. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny Vol. 118, N ^o 12, pp. 565–567, December, 1994 Presented by E. D. Gol'dberg, Member of the Russian Academy of Medical Sciences     

Variation in antiinfectious nonspecific resistance of the organism caused by cholinergic stimulation

Cholinergic stimulation (acetylcholine, aceclidine, armin) is found to improve antiinfectious nonspecific resistance in mice. The effect depends on the dose of cholinomimetic (armin), is maximal during the first 18 hours of the infectious process, and is determined by serum antibacterial activity, lysozyme activity, and the function of neutrophils and natural killers. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, N ^o . 8, pp. 164–166, August, 1995 Presented by Yu. A. Romanov, Member of the Russian Academy of Medical Sciences     

Pathomorphologic investigation of intraorgan arteries in patients with coarctation of the aorta

A stereotypic angiospasm develops in intraorganic arteries during coarctation of the aorta, which is characterized by different functional impacts: resistance in the basin of elevated vascular pressure and pressure and bloodflow regulation in the hypotension basin. The most marked structural changes are observed in the renal and coronary arteries. Changes in the small coronary arteries are mainly due to myocardial hypertrophy, whereas in the larger ones they are caused by the increased pressure transferred from the aorta. The degree of structural changes in the larger coronary arteries is greater than in the small arteries. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, N ^o 3, pp. 332–336, March, 1995     

Mechanisms of the vasodilator effect of nitroglycerin and chlorpromazine and specificities of their interaction in a model of isolated rat thoracic aorta

The effect of nitroglycerin and chloropromazine (plegomazin) on norepinephrine-induced contraction of rat aorta rings is studied in experiments on the intact and deendothelized aorta, and the combined myolytic effect of the two preparations is assessed. A possible cross-tolerance between nitroglycerin and chloropromazine is studied in experiments simulating the development of vascular tolerance of nitroglycerin. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N ^o 9, pp. 273–276, September, 1994 Presented by P. V. Sergeev, Member of the Russian Academy of Medical Sciences     

Endogenous intoxication syndrome in patients in the late stages of obliterating atherosclerosis of the vessels

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 115, N ^o 2, pp. 148–151, February, 1993     

Inhibition of the development of experimental tumors of the cervix and vagina by tinctures from biomass of cultured ginseng cells and its germanium-selective stocks

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol.116, N ^o 11, pp. 534–536, November, 1993     

Effect of chorionic gonadotropin on lactate dehydrogenase and alcohol dehydrogenase activity in the pathologically altered liver

Chorionic gonadotropin is shown to alter lactate dehydrogenase and alcohol dehydrogenase activity in the pathologically altered liver and to exert a regulatory effect on the catalytic properties of these enzymes. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N ^o 6, pp. 590–591, June, 1994 Presented by Yu. A. Romanov, Member of the Russian Academy of Medical Sciences     

Pharmacological analysis of pentagastrin-modulated behavior caused by stimulation of the ventromedial hypothalamus

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 8, pp. 178–181, August, 1993     

Effect of nifedipine and ruthenium red on the contractile function and oxidative metabolism of the myocardium

Translated fromByulleten' Experimental'noi Biologii i Meditsiny, Vol. 115, N ^o 4, pp. 375–378, April, 1993     

Effect of some lectins on the cholinergic structures of the frog heart

The effect of lectins (phytohemagglutinin — PHA, concanavalin A — ConA,Pisum sativum lectin — PSL,Ricinus communis lectin — RCL, and pokeweed mitogen — PWM) on the cardiac cholinoceptors is studied in experiments on isolated hearts of maleRana temporaria frogs. The test lectins in concentrations from 10⁻²³ to 10⁻³ are shown to exhibit cholinomimetic properties. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N ^o 9, pp. 252–255, September, 1994 Presented by A. D. Ado, Member of the Russian Academy of Medical Sciences