中医五音疗法在肿瘤内科化疗患者中的应用

目的探讨中医五音疗法在肿瘤内科化疗患者中的应用效果。方法采用便利抽样法,选取2017年2月—2019年2月河北北方学院附属第一医院150例肿瘤内科行2个周期化疗的患者为研究对象,根据随机及患者自愿原则将其分为观察组(75例)和对照组(75例)。对照组予以常规化疗与普通音乐干预,观察组在化疗基础上予以中医五音疗法。比较两组化疗前后采用Piper疲乏量表(PFS)评价患者癌因性疲乏程度,采用平均动脉压(MAP)、心率、一氧化氮、超氧化物歧化酶(SOD)评估患者应激状态,采用汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)、心理弹性量表简化表(CD-RISC)评估患者心理状态,采用癌症生活质量评估问卷(QLQ-30)评估患者生活质量,比较两组患者不良反应发生率。结果观察组化疗1周、化疗2周时PFS评分低于对照组,差异有统计学意义(P<0.05);观察组化疗2周一氧化氮水平低于对照组,SOD水平高于对照组,两组比较差异有统计学意义(P<0.05);观察组化疗2周时HAMA评分、HAMD评分低于对照组,CD-RISC评分高于对照组,差异有统计学意义(P<0.05);观察组化疗1周、化疗2周QLQ-30评分高于对照组,差异有统计学意义(P<0.05);观察组化疗后1个月内恶心、呕吐、骨髓抑制发生率低于对照组,差异有统计学意义(P<0.05)。结论中医五音疗法可有效减轻肿瘤内科化疗患者癌因性疲乏、应激状态,提高其心理韧性和生活质量,减少不良反应,值得在临床推广实践。     

慢性疲劳综合征的中医特色疗法研究进展

本文通过检索国内外相关文献,对中医护理特色疗法治疗慢性疲劳综合征（CFS）的相关研究进行综述,从CFS的病因机制、辨证分型、中西医治疗在CFS患者护理中的临床应用等方面进行总结概括,以期为中医护理特色疗法在临床上的灵活运用提供借鉴。     

中医诊治慢性疲劳综合征概况

中医诊治慢性疲劳综合征概况陈家旭（北京中医药大学，北京１０００２９）ＢｒｉｅｆＯｕｔｌｉｎｅｏｎＤｉａｇｎｏｓｉｓ＆ＴｒｅａｔｍｅｎｔｏｆＣｈｒｏｎｉｃＦａｔｉｇｕｅｓｙｎｄｒｏｍｅｂｙＴｒａｄｉｔｉｏｎａｌＣｈｉｎｅｓｅＭｅｄｉｃａｌＳｃｉｅｎｃｅ...     

慢性疲劳综合征的中医论治

随着现代生活节奏的加快,生存竞争的加剧,人们面临着前所未有的巨大压力,很多人感到来自身体和心理上的疲惫,情绪上的障碍,且难于排解,因集中在健康人群中,人们习惯称之为亚健康人群。由于目前这个人群的数量仍在继续增     

慢性疲劳综合征

慢性疲劳综合征霍万户慢性疲劳综合征（ｃｈｒｏｎｉｃｆａｔｉｇｕｅｓｙｎｄｒｏｍｅ：ＣＦＳ）目前在欧美以及日本的新闻媒体称之为“第二爱滋病”。群众和医学界对此都很关注。如美国近年连续召开国际性的慢性疲劳综合征（下略称ＣＦＳ）的专题学术会议探讨其病因、诊...     

慢性疲劳综合征患者生存质量和疲劳特征及中医推拿干预研究

目的:探讨慢性疲劳综合征患者的生存质量(QOL)和疲劳特征及中医推拿的干预效应。方法:将30例慢性疲劳综合征患者作为治疗组,给予推拿治疗。手法以一指禅推法、滚法和按揉法为主;部位以督脉、膀胱经、胃经为主,主穴取风府、腰阳关、心俞、脾俞、肝俞、合谷、太溪;隔日治疗1次,共治疗10次。30例正常人为对照组,不予任何处理。借助SF-36健康调查问卷(SF-36)和MFI-20多维疲劳问卷测量工具评估两组对象的QOL和疲劳特征,并观察推拿治疗前、后治疗组患者相应量表的积分变化。结果:慢性疲劳综合征患者SF-36生理功能、生理职能、身体疼痛、总体健康、活力、社会功能、情感职能和精神健康等八个维度积分低于正常对照组,差异有显著性意义(P0.001)。MFI-20总体疲劳、生理疲劳、活动减少、兴趣减少和精神疲劳等五个维度积分高于正常对照组,差异有显著性意义(P0.001);10次推拿治疗后,治疗组SF-36八个维度上积分都表现为升高的趋势,除生理职能和身体疼痛外,其余六项因子前后差异配对比较都有显著性意义(P0.05)。MFI-20五个维度积分都表现为降低的趋势,前后差异配对比较皆有显著性意义(P0.05)。结论:慢性疲劳综合征患者存在QOL下降和主观疲劳的特性;中医推拿可提高慢性疲劳综合征患者的QOL,调整疲劳状态。     

慢性疲劳综合征

慢性疲劳综合征 (chronic fatigue syndrom e,CFS)是一组以无力、疲劳、睡眠质量差、认知功能下降及一些躯体症状 ,如反复咽痒、肌肉痛、头痛、关节痛为特征的临床综合征 [1 ]。1994年美国疾病控制与防御中心明确了慢性疲劳综合征的定义及诊断标准 ,使该病病因、病理及治疗的研究进入了一个更精确更深入的阶段 ,本文对其研究进展综述如下。1　历史的回顾及诊断标准的建立在 19世纪中期 ,首先由美国神经病学家 Charles Beard描述 ,其症状与现在定义的 CFS相似 ,并命名为神经衰弱。 2 0世纪初 ,放弃慢性疲劳综合征诊断 ,而称为流行性神经…     

护士易患慢性疲劳综合征

近年来慢性疲劳综合征（ＣＦＳ）引起护理界关注,通过对有关文献的研究综述了ＣＦＳ的由来、临床特点、诊断、病因、护理人员发病情况。     

左旋肉碱治疗慢性疲劳综合征的研究

目的　通过对 10例慢性疲劳综合征 (chronicfatiguesyndrome ,CFS)病人的左旋肉碱治疗 ,探讨左旋肉碱缺乏在CFS发病中的作用。方法　经临床确诊的血浆左旋肉碱含量低于正常的CFS病人 10例 ,进行静脉注射左旋肉碱治疗。观察疗效并复查血浆左旋肉碱的含量。结果　 10例病人全部有效 ,其中 7例完全治愈 ,3例症状明显改善。 10例病人治疗后血浆左旋肉碱含量全部达到正常水平。结论　左旋肉碱缺乏是造成CFS的一个重要原因。对CFS病人应常规进行血浆左旋肉碱的测定 ,对缺乏者应进行左旋肉碱的补充治疗。     

认知行为干预对食管癌患者术后疲劳综合征的影响

目的：探讨认知行为干预对食管癌患者术后疲劳综合征的效果。方法：选择食管癌根治术后患者80例,按入院顺序分为对照组与观察组各40例。对照组给予常规护理,观察组在常规护理的基础上实施认知行为干预,比较两组患者术后疲劳情况。结果：观察组不同时期的术后疲劳评分、心境评分均低于对照组（P<0.05）;观察组的术后康复情况也优于对照组（P<0.05）;两组患者的术后并发症情况并无明显差异（P＞0.05）。结论：认知行为干预可以改善食管癌患者的术后疲劳综合征,对于患者术后心境和术后康复有一定的积极作用。     

Traditional chinese medicine for chronic fatigue syndrome

More and more patients have been diagnosed as having chronic fatigue syndrome (CFS) in recent years. Western drug use for this syndrome is often associated with many side-effects and little clinical benefit. As an alternative medicine, traditional Chinese medicine (TCM) has provided some evidences based upon ancient texts and recent studies, not only to offer clinical benefit but also offer insights into their mechanisms of action. It has perceived advantages such as being natural, effective and safe to ameliorate symptoms of CFS such as fatigue, disordered sleep, cognitive handicaps and other complex complaints, although there are some limitations regarding the diagnostic standards and methodology in related clinical or experimental studies. Modern mechanisms of TCM on CFS mainly focus on adjusting immune dysfunction, regulating abnormal activity in the hypothalamic-pituitary-adrenal (HPA) axis and serving as an antioxidant. It is vitally important for the further development to establish standards for 'zheng' of CFS, i.e. the different types of CFS pathogenesis in TCM, to perform randomized and controlled trials of TCM on CFS and to make full use of the latest biological, biochemical, molecular and immunological approaches in the experimental design.     

慢性疲劳综合征研究新进展

近年来慢性疲劳综合征已引起医学界的广泛关注。从慢性疲劳综合征发病原因、发病机制和干预措施方面综述了最新研究进展。     

慢性疲劳综合征研究新进展

近年来慢性疲劳综合征已引起医学界的广泛关注.从慢性疲劳综合征发病原因、发病机制和干预措施方面综述了最新研究进展.     

How to exercise people with chronic fatigue syndrome: evidence-based practice guidelines

Eur J Clin Invest 2012; 42 (10): 1136-1144 ABSTRACT: Background Despite the large number of studies emphasizing the effectiveness of graded exercise therapy (GET) and cognitive behavioural therapy (CBT) for people with chronic fatigue syndrome (CFS), clinicians are left wondering how exactly to apply exercise therapy to their patients with CFS. The aim of this literature review is to identify the appropriate exercise modalities (i.e. exercise duration, mode, number of treatment sessions, session length, duration of treatment, exercise intensity and whether or not to apply home exercise program) for people with CFS. Materials and methods All studies that were identified through electronic databases (PubMed and PEDro) were assessed for methodological quality by using selection criteria (Delphi score). Results In this literature review, 12 studies fulfilled all study requirements. One study had a low methodological quality. The parameters used in the GET and CBT interventions were divided into subgroups: (i) time or symptom contingent, (ii) exercise frequency and (iii) exercise modality. Conclusion The lack of uniformity in outcome measures and CFS diagnostic criteria make it difficult to compare the findings across studies. Based on the available evidence, exercise therapy for people with CFS should be aerobic and must comprise of 10-11 sessions spread over a period of 4-5?months. A time-contingent approach is preferred over a symptom-contingent way of exercising. In addition, people with CFS can perform home exercises five times a week with an initial duration of 5-15?min per exercise session. The exercise duration can be gradually increased up to 30?min.     

The association between experimental and clinical pain measures among persons with fibromyalgia and chronic fatigue syndrome.

Evoked or experimental pain is often used as a model for the study of clinical pain, yet there are little data regarding the relationship between the two. In addition, there are few data regarding the types of stimuli and stimulus intensities that are most closely related to clinical pain. In this study, 36 subjects with fibromyalgia (FM), chronic fatigue syndrome (CFS), or both syndromes were administered measures of clinical pain and underwent a dolorimetry evaluation. Subjects also underwent experimental pain testing utilizing heat and pressure stimulation. Stimulation levels evoking low, moderate and high sensory intensity, and comparable levels of unpleasantness, were determined for both types of stimuli using random staircase methods. Clinical pain was assessed using visual analogue ratings and the short form of the McGill Pain Questionnaire (MPQ). Ratings of heat pain sensation were not significantly associated with clinical pain ratings, with the exception of unpleasantness ratings at high stimulus intensities. Pain threshold and tolerance as assessed by dolorimetry were significantly associated with average measures of clinical pain. Both intensity and unpleasantness ratings of pressure delivered using random staircase methods were significantly associated with clinical pain at low, moderate and high levels, and the strength of the association was greater at increasingly noxious stimulus intensities. These findings suggest that random pressure stimulation as an experimental pain model in these populations more closely reflects the clinical pain for these conditions. These findings merit consideration when designing experimental studies of clinical pain associated with FM and CFS.     

慢性疲劳综合征的饮食行为和生活习惯特征

目的：探讨慢性疲劳综合征（CFS）患者的饮食行为和生活习惯的特征,为临床康复干预提供理论依据。方法：对329例CFS患者和363例健康体检者分别采用疲劳评定量表、饮食行为量表和生活习惯调查表进行调查。结果：饮食行为量表结果显示,CFS人群的代理摄食因子和饮食内容因子积分显著高于对照组（P〈0.05）,而体质认识、饮食心理、满腹感、饮食方法、饮食节律等因子积分两组之间差异无显著性意义。生活习惯调查表显示．CFS人群的“外出办事次数”显著低于对照组（P〈0．05）,“自觉体力状况良好程度”和“目前身体状况的良好程度”显著高于对照组（P〈0.05）,且CFS人群多有“便秘习惯”（P〈0．05）。结论：慢性疲劳综合征多伴有代理摄食心理和饮食内容的不合理,对健康概念的认识不正确,存在不健康的生活习惯。采取认知行为治疗、饮食疗法和运动疗法为主的康复干预措施将有助于控制和预防CFS的发生发展。     

A multiconvergent approach to the rehabilitation of patients with chronic fatigue syndrome: a comparative study

Objectives

This study investigated the efficacy of a rehabilitation technique for the treatment of chronic fatigue syndrome that was developed by a physiotherapist. Data collected retrospectively from a pilot study indicated that patients benefited from this multiconvergent approach, so further assessments were warranted.

Design

Treatment efficacy was assessed by comparing the primary and secondary outcome measures of patients attending multiconvergent therapy (MCT) with those of patients attending relaxation therapy and a group of non-intervention controls.

Setting

The active treatment took place at a clinic within the physiotherapy outpatient unit. Relaxation therapy and all assessments were conducted at the psychology unit.

Participants

Thirty-five participants, fitting the Centers for Disease Control and Prevention criteria for chronic fatigue syndrome, were recruited from two outpatient clinics and an existing patient panel.

Intervention

Patients were assigned to either MCT (n = 12) or relaxation therapy (n = 14). Nine participants who received general medical care were used as a comparison group.

Main outcome measures

The Karnofsky performance scale was used as the primary outcome measure of function. Secondary outcome measures assessing overall improvement in patient condition, fatigue and disability levels were also administered.

Results

A significant percentage of the patients attending the MCT sessions showed improvement in the primary outcome score used to measure the success of the treatment (MCT = 83%, relaxation = 21%, controls = 0; P < 0.001). A significant percentage of this group also reported improvement in their overall condition (MCT = 92%, relaxation = 64%, controls = 22%; P < 0.001), lower fatigue levels (MCT = 83%, relaxation = 57%, controls = 11%; P < 0.001) and lower levels of disability (MCT = 75%, relaxation = 43%, controls = 11%; P = 0.032) immediately post-therapy. In addition, these improvements were maintained at 6-month follow-up.

Conclusions

Outcomes from this small preliminary study were encouraging. The multiconvergent approach produced significant improvements for standardised primary and secondary outcome measures. Further research is required to examine the efficacy of this approach over time, and its effectiveness on a larger scale within the primary healthcare setting using additional therapists trained in the technique.     

Diagnostic accuracy of symptoms characterising chronic fatigue syndrome

Purpose.?To determine the diagnostic accuracy for single symptoms and clusters of symptoms to distinguish between individuals with and without chronic fatigue syndrome (CFS).

Methods.?A cohort study was conducted in an exercise physiology laboratory in an academic setting. Thirty subjects participated in this study (n == 16 individuals with CFS; n == 14 non-disabled sedentary matched control subjects). An open-ended symptom questionnaire was administered 1 week following the second of two maximal cardiopulmonary exercise tests administered 24?h apart.

Results.?Receiver operating characteristics (ROC) curve analysis was significant for failure to recover within 1 day (area under the curve == 0.864, 95%% confidence interval [[CI]]: 0.706–1.00, p == 0.001) but not within 7 days. Clinimetric properties of failure to recover within 1 day to predict membership in the CFS cohort were sensitivity 0.80, specificity 0.93, positive predictive value 0.92, negative predictive value 0.81, positive likelihood ratio 11.4, and negative likelihood ratio 0.22. Fatigue demonstrated high sensitivity and modest specificity to distinguish between cohorts, while neuroendocrine dysfunction, immune dysfunction, pain, and sleep disturbance demonstrated high specificity and modest sensitivity. ROC analysis suggested cut-point of three associated symptoms (0.871, 95%% CI: 0.717–1.00, p < 0.001). A significant binary logistic regression model (p < 0.001) revealed immune abnormalities, sleep disturbance and pain accurately classified 92%% of individuals with CFS and 88%% of control subjects.

Conclusions.?A cluster of associated symptoms distinguishes between individuals with and without CFS. Fewer associated symptoms may be necessary to establish a diagnosis of CFS than currently described.