破裂腹主动脉瘤的诊断和外科治疗

随着外科技术和围手术期治疗水平日益提高，腹主动脉瘤择期手术治疗死亡率已控制在5％以内，但破裂腹主动脉瘤（ruptured abdominal aortic aneurysm，RAAA）的死亡率一直在40％～70％，如果包括尚未到达医院的RAAA患者，死亡率可达80％～90％，RAAA被美国列为第13位死亡原因。目前，及时准确的诊断和快速有效的外科治疗仍是降低RAAA死亡率的关键。     

腹主动脉瘤手术治疗进展

我国血管外科事业在近五十年里取得了前所未有的发展 ,这是广大血管外科专业人员共同努力的结果。进入 2 1世纪后 ,血管外科将得到更加迅速的发展。本专题特邀国内在此领域有突出贡献的专家 ,就目前血管外科的现状与发展趋势作一讲座 ,希望这一方小小的论坛 ,能对血管外科新技术的推广起一点的推动作用 ,并能吸引更多的有志青年加入到血管外科专业医师的队伍中来     

One-stage Surgical Management of Concomitant Abdominal Aortic Aneurysm and Gastric or Colorectal Cancer

One-stage surgical management of concomitant abdominal aortic aneurysm (AAA) and gastric or colorectal cancer should provide certain benefits. We reviewed the records of 21 patients with both AAA and gastric or colorectal cancer who underwent one-stage surgical management. Four had distal gastrectomy, 2 had total gastrectomy, and 5 had abdominoperineal rectal resection transperitoneally; 3 had total gastrectomy transperitoneally and AAA repair extraperitoneally. Two underwent right hemicolectomy and thromboexclusion of the AAA. Two had creation of a temporary ileostomy and implantation of an interposition graft. Two underwent left hemicolectomy, creation of a temporary transversostomy, and implantation of an interposition graft. One had a Hartmann’s procedure and implantation of a bifurcated prosthetic interposition graft for AAA. There were no operative deaths or serious postoperative complications. One patient had colorectal ischemia that resolved with conservative treatment. Eighteen of the 21 patients (85.7%) were alive 10 months to 14 years postoperatively. In conclusion, one-stage surgical treatment of concomitant AAA and gastric or colorectal cancer is well tolerated and can avoid the time, financial costs, and patient anxiety involved in a second operation.     

破裂腹主动脉瘤的外科治疗及预后

目的探讨破裂腹主动脉瘤的诊断、治疗方法及影响预后的因素。方法回顾性分析1999年4月至2005年12月期间我院收治的23例肾动脉下破裂腹主动脉瘤患者的临床资料，其中男15例，女8例；年龄35～78岁，平均65岁。自知有腹主动脉瘤者7例，有腹部搏动性包块者6例，术前行急诊彩超和（或）CT检查确诊15例。所有患者均行急诊手术治疗。根据术中情况采取肾动脉下腹主动脉钳夹阻断或腹主动脉腔内球囊阻断，控制出血后行人造血管移植术。结果手术后30d内死亡9例（39％），死亡原因为出血性休克所致的急性肾功能衰竭4例、多器官功能衰竭3例、呼吸循环衰竭2例。结论手术治疗是对破裂腹主动脉瘤的有效治疗，根据术中情况采取不同的方法阻断破裂口近端腹主动脉以控制出血是手术的关键。急性心脑血管疾病、急性肾功能衰竭及肺部并发症是术后的主要并发症及死亡原因。     

The Surgical Management of Ruptured Abdominal Aortic Aneurysm: A Ten -Year Experience

Ninety consecutive patients with ruptured abdominal aortic aneurysms were treated surgically. The hospital mortality was 42% for the whole period, but was reduced to 33% for the last five years. Case management is outlined, with emphasis on ancesthetic and fluid management, and causes of mortality and morbidity are presented. The late results were also discussed and an actuarial survival curve was calculated.     

25例腹主动脉瘤的外科治疗

为了提高腹主动脉瘤外科手术的成功率及减少术后并发症的发生率，总结报道了２５例腹主动脉瘤的治疗经验。所有病人术前ＤＳＡ、ＭＲＩ等检查明确诊断，根据瘤体的情况行瘤体切除、人工血管或同种异体血管移植手术。结果本组病人手术死亡率１６％，无一例出现因腹主动脉阻断而发生主要脏器缺血性损伤的并发症。作者认为，腹主动脉瘤均应尽早行外科手术治疗。已破裂者或即将破裂的腹主动脉瘤是急诊手术的指征。     

腔内修复术治疗破裂型腹主动脉瘤的效果评价

目的分析破裂型腹主动脉瘤(ruptured abdominal aneurysm,r AAA)行腔内修复术(endovascular aortic aneurysm repair,EVAR)与开放手术早期结果,评价EVAR治疗的效果。方法回顾性收集我院2004年1月~2014年1月收治的48例r AAA患者临床资料,根据其手术与否、手术方式的不同分为术前死亡组(n=20)、EVAR组(n=14)和开放手术组(n=14),三组性别、年龄等一般资料比较无统计学差异(P0.05),EVAR组和开放手术组在瘤体直径、收缩压、舒张压方面比较差异均无统计学意义(P0.05)。结果 EVAR组入院至检查时间为(1.2±0.8)h,与开放手术组(7.5±7.1)h比较差异有统计学意义(P=0.006);EVAR组检查至手术时间为(1.8±1.3)h,与开放手术组(16.8±17.7)h比较差异有统计学意义(P=0.007)。死亡组入院至死亡时间与EVAR组比较差异有统计学意义(P0.009)。EVAR组手术时间为(2.3±0.7)h,与开放手术组(5.6±2.0)h比较差异有统计学意义(P0.001);EVAR组的术中出血量为(142.9±279.3)ml,与开放手术组的(3 528.6±3 252.3)ml间差异有统计学意义(P0.001);EVAR组的输血量为(985.7±2 148.7)ml,与开放手术组的(3 100.0±2 285.1)ml间差异有统计学意义(P=0.018);EVAR组的住院时间为(7.1±2.7)d,与开放手术组的(13.7±4.9)d间差异有统计学意义(P0.001);EVAR组的总费用为(20.9±5.8)万元,与开放手术组的(10.1±11.5)万元间差异有统计学意义(P=0.005)。两组并发症率比较,差异无统计学意义(P=0.430)。结论缩短院内抢救准备时间,是r AAA成功救治的要点。EVAR应作为r AAA的一线治疗方案。     

Impact of Aortic Diameter on the Outcome of Surgical Treatment of Abdominal Aortic Aneurysm

Several recent articles have discussed ultrasonographic surveillance of small abdominal aortic aneurysms (AAA). The purpose of this study was to evaluate the impact of lesion size on immediate morbidity and mortality after surgical treatment of AAA. More specifically we investigated whether the mortality rate was lower after treatment of AAA measuring <50 mm in diameter than that resulting from treatment of larger aneurysms. The study population consisted of 309 consecutive patients (289 men and 20 women) who underwent elective surgical repair of infrarenal AAA. Mean age was 69.9 years. Lesion size was measured on preoperative CT scans. Mean transverse diameter was 55 mm (range, 32 to 120 mm). Patients were divided into two groups on the basis of diameter size: group I included 165 patients with AAA <50 mm in diameter and group II included 144 patients with AAA <50 mm. In our experience, morbidity and mortality rates were comparable in patients undergoing surgery for small and large AAA. This finding does not support previous claims that lower operative mortality warrants early surgical treatment.     

腹主动脉瘤72例诊断和外科治疗分析

目的总结分析腹主动脉瘤的诊断和外科治疗经验。方法回顾性分析自1995年1月至2004年2月我科收治的72例腹主动脉瘤患者的临床资料。术前根据患者症状和体征，分别采用彩色多普勒超声、CT、MRA和DSA检查明确诊断和拟定手术方案。其中肾动脉下型腹主动脉瘤行择期腹主动脉瘤切除、人造血管移植术58例；肾动脉上型假性腹主动脉瘤行择期囊内修复术1例；肾动脉上型腹主动脉瘤行择期腹主动脉瘤切除人造血管移植术1例；腹主动脉瘤破裂行急诊腹主动脉瘤切除、人造血管移植术12例。结果彩色多普勒超声、CT、MRA和DSA检查均能确诊腹主动脉瘤；58例肾动脉下型腹主动脉瘤切除、人造血管移植择期手术，术后死于多器官功能衰竭2例，死亡率为3．45％，其余病例和2例肾动脉上型腹主动脉瘤均获临床治愈。12例腹主动脉瘤破裂者临床治愈7例，5例术后死于多器官功能衰竭，死亡率为41．67％。结论加强腹主动脉瘤手术患者围手术期评估和管理，尤其是保证术中内环境稳定，减少术中失血，可使腹主动脉瘤手术更为安全、有效。     

破裂腹主动脉瘤的外科治疗体会(附20例报道)

目的探讨破裂腹主动脉瘤的诊断和外科治疗方法。方法回顾性分析2000年1月至2010年12月期间新疆维吾尔自治区人民医院收治的20例破裂腹主动脉瘤患者的临床资料。结果男18例,女2例;年龄31～82岁,平均65.4岁。所有患者中突发性腹或腰背部疼痛20例,血压下降和(或)休克11例,发病前有明确腹主动脉瘤病史7例。所有患者均经彩超、CTA或手术探查确诊。19例患者采用传统开腹手术,1例行腔内支架人工血管置入术。20例患者中围手术期死亡4例,死亡率为20%,死亡原因为循环衰竭1例,多器官功能障碍综合征3例。存活的16例患者恢复顺利。结论手术治疗破裂腹主动脉瘤有效,早期诊断,急诊外科手术,是降低病死率的关键。     

Emergency Non-ruptured Abdominal Aortic Aneurysm

OBJECTIVES: To investigate symptoms and early mortality (<30 days) following open surgery for emergency, symptomatic non-ruptured abdominal aortic aneurysm (AAA). DESIGN: Retrospective cohort study. PATIENTS AND METHODS: During the period 1983-1994, 129 patients had an emergency admission, followed by surgery, for symptomatic non-ruptured AAA. Sixty-one received surgery within 24 h of admission and 68 received surgery more than 24 h after admission (median 135 h, inter-quartile range: 51-239 h). During the same period 239 patients had elective surgery for non-ruptured AAA. Early mortality (<30 days), symptoms and co-morbidities were recorded. Data were retrieved from the patient records. RESULTS: Mortality (30 days) was 18% in the 61 patients having surgery within 24 h of emergency admission for non-ruptured AAA. Mortality following either delayed surgery (semi-elective) after emergency admission or elective surgery was 4.2% (p=0.0002). Four out of 11 patients who died within 30 days following an acute operation had previously been declared unfit for elective surgery. One additional emergency patient had been found unfit for open surgery, but survived a delayed operation. CONCLUSION: The high mortality rate of patients with non-ruptured, symptomatic AAA undergoing surgery within 24 h of admission appears to be influenced by several factors, including co-morbidities and the acute operation. We propose that the 30-day mortality for non-ruptured AAA should be reported in two categories: mortality rate for elective surgery and mortality for surgery performed within 24 h of emergency admission. The term 'emergency non-ruptured' is a suitable term for the latter group.     

腹主动脉瘤腔内修复术后内漏的诊断与治疗

腹主动脉瘤（AAA）腔内修复术（EVAR）是目前大动脉病变腔内治疗最成熟的技术之一。AAA EVAR术后内漏指支架型血管置入后，在支架型血管腔外、被旷置的瘤体及邻近血管腔内出现持续性血流的现象。内漏是AAA EVAR术后最为常见、对疗效影响很大的并发症，其发生率大约15％～50％。内漏可导致瘤体进一步增大甚至破裂。目前，内漏的机理尚不完全明确，诊断与治疗方面也存在争议。现根据我院临床经验，结合近年来相关文献报道探讨AAA EVAR术后内漏的诊治。     

Complex Abdominal Aortic Aneurysm Repair

Vascular surgery is a challenging discipline and complex aneurysms can present an entire range of technical difficulties. To overcome these problems good technical skills are mandatory. However, it is also worth remembering a few basic rules:

? The simplest solution is often the best.

? All cases need careful planning, including that of the approach

? A successful anastomosis requires good aortic tissue

? Minimal dissection reduces morbidity.     

Bifurcated Endovascular Grafting for Abdominal Aortic Aneurysm

x = 55.4 mm) underwent bifurcated endovascular grafting (Guidant/EVT, Menlo Park, CA) over an 18-month period. We concluded that bifurcated endovascular grafting with the EVT? device provides reliable and reproducible aneurysm exclusion with short hospital recovery and low morbidity.