新冠肺炎流行期间医学生的抑郁焦虑症状及相关因素

目的:了解新冠肺炎流行期间医学生的抑郁、焦虑症状及相关因素。方法:使用在线调查平台"问卷星"创建问卷向医学生发放,收回有效问卷5593份。采用自编一般资料问卷、病人健康问卷(PHQ-9)、广泛性焦虑量表(GAD-7)进行调查。结果:有1964名(35.1%)医学生存在抑郁症状,1255名(22.4%)医学生存在焦虑症状。Logistic回归分析显示,女性、大二、大三、大四、关注疫情时间长为抑郁症状(OR=1.28、1.30、1.36、1.25、1.09)、焦虑症状(OR=1.16、1.24、1.46、1.31、1.17)的危险因素;对疫情知识了解为抑郁、焦虑症状的保护因素(OR=0.79、0.82)。结论:新冠肺炎流行期间,医学生抑郁、焦虑症状的检出率较高。     

新冠肺炎流行期间国际航行船舶海员抑郁状况及相关因素

新冠肺炎(COVID-19)的流行给海员群体带来了多重困境[1]。各国为防止疫情传播而采取的旅行和个人行动限制导致超过40万名海员无法进行正常换班,超期服务问题突出[2]。本研究针对国际航行海员这一特殊群体,探讨新冠肺炎疫情大流行形势下的抑郁现状及其相关因素,为实施有针对性的干预措施提供科学依据。     

新冠肺炎患者焦虑症状及相关因素

目的:调查新冠肺炎患者的焦虑症状并分析相关因素。方法:新冠肺炎患者108例,采用自编一般资料调查表、广泛性焦虑量表(GAD-7)、简易应对方式量表(SCSQ)进行调查。结果:GAD-7总分(10.3±4.5)分。对GAD-7各条目进行秩和检验发现,有焦虑症状患者的GAD-7得分大于无焦虑症状患者(P<0.05)。GAD-7总分与积极应对得分呈负相关(r=-0.44,P<0.001),与消极应对得分呈正相.关(r=0.31,P<0.01)。二分类logistic回归分析显示,有发热症状、有接触史是焦虑症状的危险因素(OR=33.40、18.13),男性、积极应对是焦虑症状的保护因素(OR=0.02、0.03)。结论:新冠肺炎患者为女性、出现发热、有接触史时其焦虑症状越严重。     

新冠肺炎疫情期间医务人员与非医务人员焦虑抑郁水平及相关因素

目的:探索新冠肺炎疫情暴发期间医务人员与非医务人员焦虑抑郁水平及相关因素。方法:通过微信公众号方式发放在线问卷,共调查医务人员170名,非医务人员217名。内容包括一般情况调查表、广泛性焦虑量表(GAD-7)、患者健康问卷(PHQ-9)和心理弹性量表(CD-RISC-10),采用logistic回归分析焦虑、抑郁情绪的相关因素。结果:医务人员中抑郁情绪检出率42.9%,焦虑情绪检出率46.5%。非医务人员抑郁情绪检出率62.7%,焦虑情绪检出率52.5%。在所有被调查者中,非医务人员(OR=0.58,95%CI:0.36～0.93,P<0.05)是抑郁情绪的危险因素,接触(疑似)感染者(OR=2.63,95%CI:1.43～4.85,P<0.01)是焦虑情绪的危险因素。心理弹性差是抑郁情绪(医务人员：OR=10.36,95%CI:3.46～31.05,P<0.001,非医务人员：OR=17.14,95%CI:6.39～45.97,P<0.001)和焦虑情绪(医务人员：OR=14.30,95%CI:4.68～43.69,P<0.001,非医务人员：OR=11...     

新冠肺炎流行期住院集中医学观察期间血液透析患者的焦虑抑郁状况

目的:评估新冠肺炎流行期间住院集中医学观察的维持性血液透析(MHD)患者焦虑、抑郁症状的发生率及相关因素。方法:选取某三甲医院血透室进行住院集中医学观察的MHD患者114例,采用焦虑自评量表(SAS)、抑郁自评量表(SDS)、领悟社会支持量表(PSSS)进行评估,比较医学观察前与观察期间的焦虑、抑郁得分;采用多因素回归分析探讨相关因素。结果:医学观察期间患者SAS得分为(33.0±7.0)分,SDS得分为(37.8±9.4);医学观察前与观察期间患者的焦虑、抑郁症状发生率差异无统计学意义(均P>0.05)。PSSS得分与SAS、SDS得分负向关联(β=-0.23、-0.29),年龄与SDS得分正向关联(β=0.26)。结论:住院集中医学观察期间,血液透析患者的焦虑、抑郁发生率并未受到影响。领悟社会支持水平高可缓解焦虑、抑郁情绪,高龄患者更易出现抑郁。     

新冠肺炎疫情期间社区精神卫生防治人员的抑郁焦虑情绪

目的:了解新冠肺炎疫情期间社区精神卫生防治人员(简称社区精防人员)的抑郁焦虑情绪及相关因素。方法:应用问卷星在715名杭州市社区精防人员中调查在新冠肺炎疫情期间的社区防治工作、疫情防控工作,用患者健康问卷(PHQ-9)和广泛性焦虑障碍量表(GAD-7)评定抑郁焦虑情绪。结果:共收集699份社区精防人员的有效问卷,PHQ-9得分(2.3±2.8),GAD-7得分(1.3±2.3),抑郁情绪检出率为18.7%(131/699),焦虑情绪检出率为10.0%(70/699)。多因素分析显示,高学历社区精防人员容易出现抑郁情绪(OR=1.77,95%CI:1.10～2.84,P<0.05)。结论:新冠肺炎疫情期间社区精防人员出现一定程度的抑郁焦虑情绪,高学历精防人员出现抑郁情绪的风险可能更高。     

孕妇的焦虑抑郁情绪对照研究

怀孕是自然的生理过程,但也会出现心理和情绪变化。有作者报道焦虑和抑郁是孕妇在妊娠期间常见的症状或寻求心理咨询的主要原因[1-3]。Ａｆｆｏｎｓｏ等人报道孕妇在妊娠期间最常见的情绪有发怒、紧张担心、病理性焦虑。大约50%的孕妇有抑郁症状[4]。国内报道11%孕妇产前有焦虑或抑郁症状[5]。本文通过对照研究,了解孕妇在妊娠期的焦虑和抑郁情绪状态,报道如下。1　资料和方法1.1　对象　　随机选择1999年7月～8月间到中山医科大学附属第三院妇产科门诊就诊的孕妇,均为初孕妇。共52人。年龄20～37岁,平均27.96±3.04岁;大专以上教育程度26人…     

新冠肺炎疫情发生前后中国大学生焦虑症状及相关因素的meta分析

目的:探讨中国大学生焦虑症状及其相关因素在新冠肺炎疫情(简称疫情)发生前后的变化。方法:检索中英文数据库,收集以焦虑自评量表(SAS)为工具研究中国大学生焦虑相关因素的文献,以纳入文献的调查时间在2020年1月前定为疫情前、此后为疫情期间,运用Stata15.1软件进行meta分析。结果:纳入疫情前文献24篇、疫情期间文献14篇。疫情期间大学生焦虑症状检出率高于疫情前(24.2%vs.21.9%)。13个因素被纳入meta分析,疫情前大四年级、独生子女、性格内向、抑郁症状、身体不健康、睡眠质量差、单亲家庭、家庭经济差是大学生焦虑症状的危险因素(OR=1.48、1.24、1.59、6.62、2.23、1.82、2.77、2.13),女性、体育锻炼、高社会支持是其保护因素(OR=0.82、0.53、0.71);疫情期间大四年级、性格内向、抑郁症状、身体不健康、睡眠质量差、家庭经济差是大学生焦虑症状的危险因素(OR=2.57、1.45、1.34、3.96、1.87、1.59),医学生、体育锻炼、高社会支持是其保护因素(OR=0.73、0.66、0.57)。结论:女性、大四年级、身体不健康、抑...     

新冠肺炎流行期间江苏省心理援助热线来电特征

目的:了解新冠肺炎流行期间心理援助热线来电问题特征及随时间变化情况。方法:收集2020年2月1日-4月30日新冠肺炎流行期间江苏省心理援助热线来电,对来电内容进行分类,对来电量随时间的变化进行分析。结果:该时段内与新冠肺炎相关的来电数为1610人次,占总来电的23.3%。来电问题包括心理问题(因疫情引发情绪行为问题;原有精神心理问题加重/复发;居家心理问题)、信息咨询和其他问题。心理问题中4月原有精神心理问题加重/复发的来电比例显著高于2月(15.7% vs.5.3%,P<0.05)。结论:新冠肺炎流行期间心理援助热线来电问题主要为心理问题和信息咨询问题,来电量随着疫情形势的好转减少。     

新型冠状病毒肺炎流行期间基于列线图预测隔离留观患者的焦虑抑郁情绪

<正>新型冠状病毒肺炎(COVID-19)因其传播速度快、传染性强及人群易感等特点,已被我国列入乙类传染病并按甲类传染病管理[1]。发热门诊隔离留观的患者具有发热等类新冠症状且面对环境的改变对心理可能带来负面影响。故本研究探讨COVID-19流行期间发热门诊隔离留观患者焦虑抑郁情绪及相关因素,以期尽早识别高危患者并进行心理干预治疗。     

Prevalent,incident, and persistent insomnia in a population-based cohort tested before (2018) and during the first-wave of COVID-19 pandemic (2020)

Study ObjectivesHigh rates of sleep and mental health problems have been reported during the COVID-19 pandemic, but most of the evidence is retrospective without pre-pandemic data. This study documented rates of prevalent, incident, and persistent insomnia and psychological symptoms during the COVID-19 pandemic (2020) compared to pre-pandemic data (2018).MethodsData were derived from a longitudinal, population-based study of insomnia in Canada. When the first lockdown started in the province of Quebec, a subsample of participants who had completed the latest 2018 follow-up were surveyed (April to May 2020) about their sleep, insomnia, and psychological symptoms since the beginning of the pandemic. Prevalence, incidence, and persistence rates of insomnia, and severity of stress, anxiety, and depressive symptoms were estimated, as well as their associations with confinement, loneliness, social support, use of electronics, and other lifestyle changes occurring during the pandemic. A sleep/health survey and validated questionnaires of insomnia, sleep quality, stress, fatigue, anxiety, and depression were administered at both assessments.ResultsThe sample consisted of 594 adults (mean age: 48.3 ± 13.1 years; 64.0% women). Prevalence of insomnia increased from 25.4% to 32.2% (symptoms) and from 16.8% to 19% (syndrome) from 2018 to 2020, for an overall 26.7% increase in insomnia rates. Of those classified as good sleepers in 2018 (n = 343), 32.6% (n = 112) had developed new insomnia during the COVID-19 pandemic. Among participants who had insomnia in 2018, the persistence rate was 76.5% 2 years later. There was a significant worsening of sleep quality, fatigue, anxiety, and depression (all ps < .005) during the COVID-19 pandemic compared to 2018. Significant associations were found between sleep and psychological symptoms and with living alone and being in confinement, lower social support, increased time using electronic devices, reduced physical exercise, and higher financial stress.ConclusionsThe COVID-19 pandemic is associated with significant increases in insomnia and psychological symptoms compared to the pre-pandemic period. Large scale public sleep and mental health intervention programs should be prioritized during and after a pandemic such as the COVID-19.     

新冠肺炎期间疫情起伏与民众心理安全感的关系

2019年新型冠状肺炎疫情的爆发给民众带来了一系列的心理冲击,这种冲击在疫情的不同时间段会表现出不同的心理形式(如认知、情绪、行为的变化)[1]。但究其本质是民众的心理安全感问题。本研究旨在调查疫情不同时间段下民众心理安全感及其他心理形式的变化,分析不同特征民众心理安全感的水平。     

Alterations in vaginal microbiota among pregnant women with COVID-19

The maintenance of vaginal microbiota is an important factor to achieve optimum pregnancy outcomes. The study aims to describe the alterations in the composition of vaginal microbiota in pregnant women with coronavirus disease 2019 (COVID-19). This was a prospective case-control study. Vaginal swabs were collected from uninfected pregnant women (n = 28) and pregnant women with COVID-19 (n = 19) during the active phase of infection and within a month after recovering from infection. The vaginal microbiota on the swabs was examined by 16S rRNA gene sequencing. Shannon index indicates that alpha diversity is significantly higher in women with COVID-19 (p = 0.012). There was a significant decrease in Firmicutes (p = 0.014) with an increase in Bacteroidota (p = 0.018) phyla and a decrease in Lactobacillus (p = 0.007) genus in women with COVID-19 than those of uninfected pregnant women. The relative abundance of L. crispatus, L. iners, L. gasseri, and L. jensenii were lower in the COVID-19 group than in uninfected pregnant women. In subgroup analysis, the amount of Ureaplasma spp. was higher in women with moderate/severe than those of asymptomatic/mild disease (p = 0.036). The study revealed that vaginal dysbiosis with low abundance of Lactobacillus species occurred in pregnant women infected with severe acute respiratory syndrome coronavirus-2. These findings may lead to new studies to elucidate the risk of pregnancy adverse outcomes related to COVID-19.     

Digital cognitive behavioral therapy for insomnia promotes later health resilience during the coronavirus disease 19 (COVID-19) pandemic

Study ObjectivesStressful life events contribute to insomnia, psychosocial functioning, and illness. Though individuals with a history of insomnia may be especially vulnerable during stressful life events, risk may be mitigated by prior intervention. This study evaluated the effect of prior digital cognitive-behavioral therapy for insomnia (dCBT-I) versus sleep education on health resilience during the COVID-19 pandemic.MethodsCOVID impact, insomnia, general- and COVID-related stress, depression, and global health were assessed in April 2020 in adults with a history of insomnia who completed a randomized controlled trial of dCBT-I (n = 102) versus sleep education control (n = 106) in 2016–2017. Regression analyses were used to evaluate the effect of intervention conditions on subsequent stress and health during the pandemic.ResultsInsomnia symptoms were significantly associated with COVID-19 related disruptions, and those who previously received dCBT-I reported less insomnia symptoms, less general stress and COVID-related cognitive intrusions, less depression, and better global health than those who received sleep education. Moreover, the odds for resurgent insomnia was 51% lower in the dCBT-I versus control condition. Similarly, odds of moderate to severe depression during COVID-19 was 57% lower in the dCBT-I condition.ConclusionsThose who received dCBT-I had increased health resilience during the COVID-19 pandemic in adults with a history of insomnia and ongoing mild to moderate mental health symptoms. These data provide evidence that dCBT-I is a powerful tool to promote mental and physical health during stressors, including the COVID-19 pandemic.Clinical Trial Registration{"type":"clinical-trial","attrs":{"text":"NCT02988375","term_id":"NCT02988375"}}NCT02988375     

新冠肺炎流行期中学生从医意愿及相关因素

目的:了解中学生在新冠肺炎流行期间的从医意愿及其相关因素。方法:在2020年3月8日-15日对全国8078名12~18岁的中学生进行在线问卷调查。采用自编调查表进行从医意愿及原因调查,患者健康问卷(PHQ-9)用于抑郁症状的筛查,广泛性焦虑量表(GAD-7)用于焦虑症状的筛查,社会支持评定量表(SSRS)用于评估个体的社会支持水平。结果:新冠疫情期间中学生有从医意愿者比率为55.1%,前3位原因分别为职业价值高、对医学感兴趣、职业受人尊重,其中29.8%的中学生在疫情爆发后由无从医意愿转为有从医意愿。无从医意愿前3位原因分别为对医学不感兴趣、工作压力大、工作忙而休息时间少。Logistic回归分析显示,女性(OR=1.31,P<0.001)、居住在城市(OR=1.14,P<0.05)、高(OR=2.70,P<0.001)或中(OR=1.48,P<0.001)社会支持水平与中学生较高的从医意愿关联;高中(OR=0.60,P<0.001)、抑郁症状(OR=0.74,P<0.001)与中学生较低的从医意愿关联。结论:新冠肺炎流行期间,中学生有从医意愿的占比超过半数,女性、居住在城市、社会支持水平较高的中学生从医意愿较高,高中生、伴有抑郁症状的中学生从医意愿较低。     

Anxiety and depression levels of healthcare workers during Covid-19 pandemic

BackgroundCoronavirus disease 2019 (covid-19), which causes a pandemic in the world, has started to appear in turkey since march 2020. Healthcare workers are at the top of the groups most at risk for covid-19 infection, which can have a negative impact on psychological state.ObjectivesIt was aimed to evaluate anxiety and depression levels among healthcare workers.Methodsthis cross-sectional study performed via an online survey in april 2020. Participants answered questions about sociodemographic features, personal views and experiences about covid-19 and the hospital anxiety and depression scale (hads).ResultsA total of 300 healthcare workers,193 men and 107 women, participated in the survey. According to hads, 44.6% of participants scored above anxiety and 68.2% scored above depression cut-off points. Being younger than 50 and taking care of covid-19 patients in hospitals were independently associated with anxiety risk. Female gender, young age (less than 50) and having comorbidity were independent risk factors for depression.ConclusionHealthcare workers were at high risk of anxiety and depression during covid-19 outbreak. For this reason, psychological support should be given, especially to the group with high risk.     

Association of COVID-19 vaccination before conception with maternal thyroid function during early pregnancy: A single-center study in China

Despite the high vaccination coverage, potential COVID-19 vaccine-induced adverse effects, especially in pregnant women, have not been fully characterized. We examined the association between COVID-19 vaccination before conception and maternal thyroid function during early pregnancy. We conducted a retrospective cohort study in Shanghai, China. A total of 6979 pregnant women were included. Vaccine administration was obtained from electronic vaccination records. Serum levels of thyroid hormone were measured by fluorescence and chemiluminescence immunoassays. Among the 6979 included pregnant women, 3470 (49.7%) received at least two doses of an inactivated vaccine. COVID-19 vaccination had a statistically significant association with both maternal serum levels of free thyroxine (FT4) and thyroid stimulating hormone (TSH). Compared with unvaccinated pregnant women, the mean FT4 levels were lower in pregnant women who had been vaccinated within 3 months before the date of conception by 0.27 pmol/L (β = −0.27, 95% confidence interval [CI], −0.42, −0.12), and the mean TSH levels were higher by 0.08 mIU/L (β = 0.08, 95% CI, 0.00, 0.15). However, when the interval from vaccination to conception was prolonged to more than 3 months, COVID-19 vaccination was not associated with serum FT4 or TSH levels. Moreover, we found that COVID-19 vaccination did not significantly associate with maternal hypothyroidism. Our study suggested that vaccination with inactivated COVID-19 vaccines before conception might result in a small change in maternal thyroid function, but this did not reach clinically significant levels.