上颌单颌拔牙与双颌拔牙矫治安氏Ⅱ类1分类错的软硬组织对比研究

目的 探讨上颌单颌拔牙与双颌拔牙矫治安氏Ⅱ类1分类错(牙合)的软硬组织改变的差异。方法 选择安氏Ⅱ类1分类患者33例,其中上颌拔除2个前磨牙(甲组)18例,双颌拔除4个前磨牙(乙组)15例,应用X线头影测量技术对其矫治前后的软硬组织的变化进行测量,分析其测量结果。结果 两组SNA、SNB、ANB矫治前后的变化无明显差异。乙组上切牙内收与上唇的变化更为显著,颏前点明显前移,下唇凸度明显减小,乙组面型突度改变较甲组更为显著。结论 上颌单颌拔牙适用于下唇和下切牙凸度小、下颌无拥挤或轻度拥挤的轻中度骨性和牙源性的安氏Ⅱ类1分类患者;双颌拔牙适用于中重度拥挤的中度骨性和牙源性的安氏Ⅱ类1分类患者。     

上颌单颌拔牙与双颌拔牙矫治安氏Ⅱ类1分类错(牙合)的软硬组织对比研究

目的探讨上颌单颌拔牙与双颌拔牙矫治安氏Ⅱ类1分类错(牙合)的软硬组织改变的差异.方法选择安氏Ⅱ类1分类患者33例,其中上颌拔除2个前磨牙(甲组)18例,双颌拔除4个前磨牙(乙组)15例,应用X线头影测量技术对其矫治前后的软硬组织的变化进行测量,分析其测量结果.结果两组SNA、SNB、ANB矫治前后的变化无明显差异.乙组上切牙内收与上唇的变化更为显著,颏前点明显前移,下唇凸度明显减小,乙组面型突度变较甲组更为显著.结论上颌单颌拔牙适用于下唇和下切牙凸度小、下颌无拥挤或轻度拥挤的轻中度骨性和牙源性的安氏Ⅱ类1分类患者;双颌拔牙适用于中重度拥挤的中度骨性和牙源性的安氏Ⅱ类1分类患者.     

上颌单颌拔牙与双颌拔牙矫治安氏Ⅱ类1分类错He的软硬组织对比研究

目的 探讨上颌单颌拔牙与双颌拔牙矫治安氏Ⅱ类1分类错He的软硬组织改变的差异。方法 选择安氏Ⅱ类1分类患者33例，其中上颌拔除2个前磨牙(甲组)18例，双颌拔除4个前磨牙(乙组)15例，应用X线头影测量技术对其矫治前后的软硬组织的变化进行测量，分析其测量结果。结果 两组SNA、SNB、ANB矫治前后的变化无明显差异。乙组上切牙内收与上唇的变化更为显著，颏前点明显前移，下唇凸度明显减小，乙组面型突度改变较甲组更为显著。结论 上颌单颌拔牙适用于下唇和下切牙凸度小、下颌无拥挤或轻度拥挤的轻中度骨性和牙源性的安氏Ⅱ类1分类患者；双颌拔牙适用于中重度拥挤的中度骨性和牙源性的安氏Ⅱ类1分类患者。     

成人非拥挤安氏Ⅱ1错(牙合)单颌拔牙矫治X线头影测量分析

目的：通过拔除上颌双侧第一前磨牙矫治成人非拥挤安氏Ⅱ1错[牙合],探讨治疗前后硬软组织的改变及意义.方法：选择非拥挤安氏Ⅱ1错[牙合]的成年患者11例,所有病例均拔除上颌双侧第一前磨牙,采用直丝弓矫治技术.将治疗前后X线头影测量结果,采用SPSS 10.0统计软件进行处理.结果：下颌骨发生了轻度后下旋转,上前牙及上唇发生了明显的内收,下前牙被压低,同时发生了轻度唇倾.结论：上颌单颌拔牙矫治成人非拥挤的安氏Ⅱ1错[牙合],改变主要发生在牙齿及牙槽骨水平,颌骨矫形作用不明显,此方法适用于牙性或轻度骨性的成人非拥挤Ⅱ1错[牙合].     

成人非拥挤安氏Ⅱ1错(牙合)单颌拔牙矫治X线头影测量分析

目的:通过拔除上颌双侧第一前磨牙矫治成人非拥挤安氏Ⅱ1错(牙合),探讨治疗前后硬软组织的改变及意义.方法:选择非拥挤安氏Ⅱ1错(牙合)的成年患者11例,所有病例均拔除上颌双侧第一前磨牙,采用直丝弓矫治技术.将治疗前后X线头影测量结果,采用SPSS 10.0统计软件进行处理.结果:下颌骨发生了轻度后下旋转,上前牙及上唇发生了明显的内收,下前牙被压低,同时发生了轻度唇倾.结论:上颌单颌拔牙矫治成人非拥挤的安氏Ⅱ1错(牙合),改变主要发生在牙齿及牙槽骨水平,颌骨矫形作用不明显,此方法适用于牙性或轻度骨性的成人非拥挤Ⅱ1错(牙合).     

单颌和双颌拔牙矫治成人骨性Ⅱ类1分类错（牙合）疗效比较

目的比较上颌单颌拔牙与双颌拔牙矫治骨性Ⅱ类1分类错胎患者的软硬组织变化,探讨掩饰性治疗成人骨性Ⅱ类错[牙合]的合适方案。方法成人骨性Ⅱ类1分类错[牙合]患者20例,单颌拔牙组18例上颁拔除两个第一前磨牙;双颌拔牙组10例上颌拔除两个第一前磨牙、下颌拔除两个第二前磨牙,将矫治前后的X线头影测量结果进行对比研究。结果矫治前后两组的U1-FH,U1-AP、H角均明显减小,UL-E、LL-E距离均明显缩小;Z角均明显增大,且差异具有统计学意义（P〈0．05）。两种拔牙模式L1-MP．LL-E、U1-L1、U1-FH、U1-AP的变化量差异具有统计学意义（P〈0．05）;UL-E变化差异无统计学意义（t=0.80,P=0．430）。治疗前,单颌拔牙组FMA,LL—E较双颌拔牙组小。结论两种拔牙矫治方法均能达到内收前牙、改善软组织侧貌的治疗目的,但双颌拔牙方案矫治效果更好;临床应用中应根据主诉及具体情况选择好适应证。     

成人非拥挤安氏Ⅱ~1错单颌拔牙矫治X线头影测量分析

目的:通过拔除上颌双侧第一前磨牙矫治成人非拥挤安氏Ⅱ1错,探讨治疗前后硬软组织的改变及意义。方法:选择非拥挤安氏Ⅱ1错的成年患者11例,所有病例均拔除上颌双侧第一前磨牙,采用直丝弓矫治技术。将治疗前后X线头影测量结果,采用SPSS10.0统计软件进行处理。结果:下颌骨发生了轻度后下旋转,上前牙及上唇发生了明显的内收,下前牙被压低,同时发生了轻度唇倾。结论:上颌单颌拔牙矫治成人非拥挤的安氏Ⅱ1错,改变主要发生在牙齿及牙槽骨水平,颌骨矫形作用不明显,此方法适用于牙性或轻度骨性的成人非拥挤Ⅱ1错。     

成人骨性Ⅱ类Ⅰ分类错 (牙合)单颌拔牙与双颌拔牙矫治的对比分析

目的对比上颌单颌拔牙与双颌拔牙矫治成人骨性Ⅱ类Ⅰ分类错牙合的疗效,探索成人骨性Ⅱ类错牙合掩饰性矫治的可行方案.方法成人骨性Ⅱ类Ⅰ分类错牙合患者17例,8例采用上颌单颌拔牙模式,9例采用双颌拔牙模式矫治,将矫治前后的X线头影测量结果进行对比分析.结果矫治后两组的UI-SN角均明显减少,Z 角明显增加(p< 0.001), 下唇突度双颌拔牙组小于单颌拔牙组,UI-SN角、Z角及前牙覆盖变化两组无差异(p> 0.05),矫治前单颌拔牙组的上唇突度大于双颌拔牙组(p< 0.05),前牙覆牙合小于双颌拔牙组(p< 0.01).结论两种拔牙矫治模式均能达到内收前牙,减少前牙覆盖,减少侧面型突度的矫治目的,且矫治效果相近.但具体应用应选择好适应症.     

伴上颌拥挤的成人骨性反(牙合)正畸矫治的临床研究

目的:评价采用拔除上下颌4个前磨牙矫治伴上颌拥挤的骨性反病例的临床效果,为临床矫治该类骨性反牙合提供一种新思路。方法:选取17～30岁伴上颌拥挤的骨性反牙合病例13例,拔除上、下颌4个第一或第二前磨牙,应用标准方丝弓固定矫治技术,分析治疗前后X线头颅侧位片各项指标变化。结果:所有病例在矫治结束后磨牙尖牙均达到Ⅰ类关系,覆牙合覆盖正常。患者硬组织改变没有显著性(p≥0.05)。L1-MP角平均减小8.4°,U1-L1角平均增大11.7°,L1-NB角平均减小10.1°,L1-NB距平均减小5.2mm,差异均有显著性(p<0.01)。软组织侧貌改善明显,Li-E距、Li-H距、Li-RL2距平均减小量分别为3.3mm、3.3mm和4.5mm,差异均有显著性(p<0.01)。结论:采用拔除4个前磨牙的方法矫治伴上颌拥挤的骨性反牙合病例是一种可尝试的矫治方法,矫治后咬合关系良好,侧貌变为直面型。     

上颌单颌拔牙矫治成人安氏Ⅱ~1错的回顾性研究

目的：探讨上颌单颌拔牙矫治成人安氏Ⅱ~1错(牙合)的适应症。方法：对治疗结束的16例上颌单颌拔除双侧第一前磨牙矫治的成人安氏Ⅱ~1错(牙合)病例,采用矫治前后照片、模型及X线头影测量对比分析的方法,进行回顾性研究评价其临床效果。结果：11例矫治效果令人满意,侧貌上唇前突明显改善,磨牙完全远中关系,尖牙中性关系,覆(牙合)覆盖正常。结论：上颌牙源性前突、下颌拥挤≤4mm、前牙覆盖≤9 mm及磨牙关系为远中尖对尖的安氏Ⅱ~1成人错(牙合)病例,应用单颌拔牙矫治可以取得满意效果。     

柠檬精油对牙周致病菌抑制作用及其安全性初步研究

目的:探讨柠檬精油对牙周致病菌的体外抗菌活性及对细胞增殖的影响。方法:采用微量液体稀释法测定柠檬精油对Pg、Fn、Aa、Pi的最小抑菌浓度(minimal inhibitory concentration,MIC)及最小杀菌浓度(minimum bactericidal concentration,MBC);以较低浓度的MIC为标准稀释LEO作为实验组,采用MTT法测定柠檬精油对HUVECs的毒性作用,明确抑菌浓度下LEO的安全性。结果:柠檬精油对牙周主要致病菌均有抑菌作用,Pg、Fn、Aa、Pi的MIC分别是9.0 g/L、4.5 g/L、4.5 g/L、9.0 g/L,Aa、Fn的 MBC是9.0 g/L,Pg、Pi的MBC未测得。1/2MIC、1/20MIC浓度的LEO能够抑制人脐静脉内皮细胞的生长,而低于1/200MIC浓度的LEO则对人脐静脉内皮细胞的生长没有影响,其中1/200MIC浓度的LEO作用明显优于0.02%的CHX。结论:体外环境中,柠檬精油对牙周致病菌Pg、Fn、Aa、Pi具有抗菌活性,低浓度应用对机体相对安全。     

Oral cancer: molecular technologies for risk assessment and diagnosis

Purpose: The effective biomarkers related to diagnosis, metastasis, drug resistance and irradiation sensitivity of oral cancers will help the pathologist and oncologist to determine the molecular taxonomy diagnosis and design the individualization treatment for the patients with oral cancers.     

Computer-assisted planning for maxillofacial prosthodontic rehabilitation

Computerized tomography (CT) planning and the use of CT derived surgical templates for implant placement have shown promise for restoring function within months after surgical reconstruction of acquired post-oncologic defects.     

Stimulated whole saliva components in children with Down syndrome

The authors report on the components of stimulated whole saliva from children with Down syndrome—including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6–10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using ortho-dianisidine.
No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.     

Effect of Pingyangmycin on human venous malformation endothelial cells

Purpose: Venous malformations are common vascular anomalies with a propensity of the head and neck. Intralesional injection of Pingyangmycin (PYM, bleomycin A5 hydrochloride) is a widely used sclerotherapy method for the treatment of venous malformation.     

牙髓再生的研究现状

目前,根管治疗术在临床上已得到了广泛的应用并成功的保存了患牙,但其仍有许多术后并发症。随着组织工程技术在口腔领域的应用,构建一种组织工程化牙髓进行牙髓-牙本质复合体的再生治疗成为可能。近年来国内外已有很多关于牙髓再生的研究,并且已经取得了一定成果。本文将对目前国内外牙髓再生的研究进展现状作一综述。     

Oropharyngeal dysphagia in amyotrophic lateral sclerosis alters quality of life

Dysphagia is one of the most important complications encountered in amyotrophic lateral sclerosis (ALS). Our aim was to determine whether oropharyngeal dysphagia impacted the quality of life (QoL) of patients with ALS. Thirty consecutive patients were recruited (31–82 years, 18 men). Swallowing function was evaluated using a standardised videofluoroscopic barium swallow. All the patients completed a specific questionnaire on quality of life in dysphagia (SWAL‐QoL) immediately after the videofluoroscopy. The results of dysphagia outcome severity scale separated 14 patients with oropharyngeal dysphagia and 16 with normal swallowing function. There was no difference in the average age, weight and body mass index of the two groups (dysphagic patients: 68 ± 11 kg versus non‐dysphagic patients: 69 ± 14 kg). Most of the dysphagic patients had a bulbar affection based on their Norris scores which determine the importance of cranial nerves illness (20 ± 8), significantly lower than those of the non‐dysphagic patients (35 ± 5) (P < 0·0001). There was no difference in the neurological peripheral symptoms evaluated by Amyotrophic Lateral Sclerosis Functional Rating Scale scores (dysphagic patients: 26 ± 7 versus non‐dysphagic patients: 27 ± 8) (ns). The swallowing quality of life questionnaire revealed that the dysphagic patients had significant burden (P < 0·001). They were affected by the necessity to applied a food selection (P < 0·01), by the increase in eating duration (P < 0·05) and described a decrease in eating desire (P < 0·05). They complained of fear regarding the risk of dysphagia (P < 0·05). They also described difficulties with oral communication (P < 0·001). All of those complained about dysphagia which impacted directly mental health (P < 0·05) and social life (P < 0·05). In conclusion, oropharyngeal dysphagia is a common symptom accompanying ALS, which alters the patient's QoL, especially social health.     

拔牙位点保存用复合温敏凝胶的构建及体外表征

目的:制备多壁碳纳米管/羟基磷灰石/壳聚糖复合温敏凝胶,探讨其作为拔牙位点保存材料的理化性能。方法:采用原位沉积方法制备多壁碳纳米管/羟基磷灰石(MWNT/ HA简称HAC)复合无机材料,将其分散至壳聚糖温敏凝胶中,制备壳聚糖/多壁碳纳米管/羟基磷灰石(CS /MWNT/HA简称CS/HAC)复合温敏凝胶,以成胶时间、孔径、孔隙率、机械强度及降解性能为指标优化配方设计,并表征复合温敏凝胶的微观形貌及理化性能。结果:以10 g/L的HAC作为补强成分加入到壳聚糖溶液中,能够在不影响成胶并保证一定孔隙率(84%)的前提下,提高材料的机械性能(抗压强度0.441 MPa),所获复合温敏凝胶具有适宜的临床操作时间(12 min),并具有可控的降解速率。结论:负载HAC的复合温敏凝胶具有良好的成型性,并具有较好的机械性能,在拔牙位点保存领域具有良好的应用前景。     

Interventional neuroradiologic procedures in the head and neck

Interventional radiology and interventional neuroradiology are evolving specialties which can aid the head and neck surgeons in the clinical management of patients with complex vascular lesions.