共查询到20条相似文献,搜索用时 31 毫秒
1.
Edílson Damke Joyce K Tsuzuki Diógenes AG Cortez Izabel CP Ferreira Thâmara A Bertoni Márcia R Batista Lucélia Donati Terezinha IE Svidzinski Márcia EL Consolaro 《BMC complementary and alternative medicine》2011,11(1):35
Background
Study of in vivo antifungal activity of the hydroalcoholic extract (HE) and n-BuOH extract (BUTE) of Sapindus saponaria against azole-susceptible and -resistant human vaginal Candida spp. 相似文献2.
Yunping Qiu Minjun Chen Mingming Su Guoxiang Xie Xin Li Mingmei Zhou Aihua Zhao Jian Jiang Wei Jia 《Chinese medicine》2008,3(1):3
Background
Herba Cistanches (Roucongrong) is effective in treating Shenxu Zheng ('kidney-deficiency syndrome'). However, the mechanisms and systemic metabolic responses to the herbal intervention are unclear. 相似文献3.
Bardia A Tiwari SK Gunisetty S Anjum F Nallari P Habeeb MA Khan AA 《Inflammation research》2012,61(4):359-365
Objective
The present study was designed to investigate the role of X-ray cross-complementing group 1 (XRCC1) and apurinic/apyrimidinic endonuclease 1 (APE1) polymorphisms in apoptosis and the risk of ulcerative colitis (UC). 相似文献4.
Objective
The aim of this study was to determine whether interleukin-23R (IL-23R) polymorphisms confer susceptibility to ankylosing spondylitis (AS). 相似文献5.
Introduction
We aimed to determine the neutralization of Neisseria meningitidis outer membrane vesicles (blebs) by humoral and cellular elements of whole blood. 相似文献6.
James RiddellIV Daniel R Kaul Petros C Karakousis Joel E Gallant Jennifer Mitty Powel H Kazanjian 《Journal of translational medicine》2007,5(1):50
Background
To describe long term outcomes of Mycobacterium avium complex (MAC) immune reconstitution inflammatory syndrome (IRIS). 相似文献7.
Weihuan Huang Xiaoli Zhang Yifei Wang Wencai Ye Vincent EC Ooi Hau Yin Chung Yaolan Li 《Chinese medicine》2010,5(1):23
Background
Radix Wikstroemiae is a common Chinese herbal medicine. The ethyl acetate fraction of the ethanolic extract of W. indica possesses potent in vitro antiviral activity against respiratory syncytial virus (RSV). This study aims to identify the antiviral components of the active fraction. 相似文献8.
María-José Ariza Miguel-Ángel Sánchez-Chaparro Francisco-Javier Barón Ana-María Hornos Eva Calvo-Bonacho José Rioja Pedro Valdivielso José-Antonio Gelpi Pedro González-Santos 《BMC medical genetics》2010,11(1):66
Background
Hypertriglyceridemia (HTG) is a well-established independent risk factor for cardiovascular disease and the influence of several genetic variants in genes related with triglyceride (TG) metabolism has been described, including LPL, APOA5 and APOE. The combined analysis of these polymorphisms could produce clinically meaningful complementary information. 相似文献9.
Background
The synapsin III (SYN III) gene on chromosome 22q is a candidate gene for schizophrenia susceptibility due to its chromosome location, neurological function, expression patterns and functional polymorphisms. 相似文献10.
Objective and design
To determine whether exposure to E. coli lipopolysaccharide (LPS) modulates adenosine A1 receptor-induced increase in plasma exudation from the intact hamster cheek pouch microcirculation. 相似文献11.
Passero LF Carvalho AK Bordon ML Bonfim-Melo A Toyama MH Corbett CE Laurenti MD 《Inflammation research》2012,61(3):255-263
Objective
Leishmania (Viannia) shawi was characterized only recently, and few studies concerning the immunogenic and protective properties of its antigens have been performed. The present study aimed to evaluate the protective potential of the five antigenic fractions isolated from L. (V.) shawi promastigotes in experimental cutaneous leishmaniasis. 相似文献12.
Philipp Ehlermann Dieter Weichenhan Jörg Zehelein Henning Steen Regina Pribe Raphael Zeller Stephanie Lehrke Christian Zugck Boris T Ivandic Hugo A Katus 《BMC medical genetics》2008,9(1):95
Background
Mutations in MYBPC3 encoding myosin binding protein C belong to the most frequent causes of hypertrophic cardiomyopathy (HCM) and may also lead to dilated cardiomyopathy (DCM). MYBPC3 mutations initially were considered to cause a benign form of HCM. The aim of this study was to examine the clinical outcome of patients and their relatives with 18 different MYBPC3 mutations. 相似文献13.
Objective
The aim of this study was to determine whether tumor necrosis factor alpha inducible protein 3 (TNFAIP3) polymorphisms confer susceptibility to rheumatoid arthritis (RA) in ethnically different populations. 相似文献14.
《Scandinavian journal of immunology》2018,88(3)
Rationale
Sufficient levels of vitamin D seem to be essential for proper immune function, and low levels might be associated to disease activity in Rheumatoid Arthritis (RA ). Most studies investigate only 25OHD and not the physiologically active vitamin D metabolite, 1,25(OH )2D.Objective
To investigate associations between serum level of vitamin D metabolites and disease activity parameters in 160 inflammatory active and treatment naïve early RA patients. Serum level of vitamin D metabolites (25OHD 2, 25OHD 3 and 1,25(OH )2D) was measured by isotope dilution mass spectrometry and radio‐immunoassays at baseline. Disease characteristics were gender, number of tender joints, number of swollen joints, DAS 28‐CRP , HAQ , VAS ‐scores, CRP , erosive status (Total Sharp Score; TSS ), ACPA and IgM‐RF ‐status. Associations were evaluated using Spearman's and Wilcoxon rank‐sum tests. The study was registered in clinical trials; trial registration number: NCT 00209859.Findings
Statistically significant inverse associations were found between the active metabolite 1,25(OH )2D and DAS 28‐CRP (P = 0.004, rho = −0.23), HAQ (P = 0.005, rho = −0.22), CRP (P = 0.001, rho = −0.25), VAS patient‐pain (P = 0.008, rho = −0.21), and a positive association was found to ACPA ‐status (P = 0.04).Conclusion
The vitamin D metabolite 1,25(OH )2D was inversely associated with disease activity and positively associated with ACPA in treatment naïve and inflammatory active early RA . The results indicate that in RA , both the degree of inflammatory activity, and the diagnostic sensitivity and specificity might affect—or might be affected by the level of vitamin 1,25(OH )2D.15.
Marjan Nassiri-Asl Schwann Shariati-Rad Farzaneh Zamansoltani 《BMC complementary and alternative medicine》2007,7(1):26
Background
Passion flower (Passiflora incarnata) is used in traditional medicine of Europe and South America to treat anxiety, insomnia and seizure. Recently, it has shown antianxiety and sedative effects in human. 相似文献16.
Hossein Hosseinzadeh Azar Hosseini Marjan Nassiri-Asl Hamid-Reza Sadeghnia 《BMC complementary and alternative medicine》2007,7(1):23
Background
Salvia leriifolia have been shown to decrease ischemia-reperfusion (I/R) injury in brain tissues. In this study, the effects of S. leriifolia aqueous and ethanolic extracts were evaluated on an animal model of I/R injury in the rat hind limb. 相似文献17.
Qing Liu Yao Tong Stephen ChoWing Sze Wing Keung Liu Lam Lam Ellie ShihngMeir Chu Christine MiuNgan Yow 《Chinese medicine》2010,5(1):25
Background
Tian Xian Liquid (TXL) is a Chinese medicine decoction and has been used as an anticancer dietary supplement. The present study aims to investigate the effects of TXL on the apoptosis of HT-29 cells and tumor growth in vivo. 相似文献18.
Background
MCF2L2, ADIPOQ and SOX2 genes are located in chromosome 3q26-27, which is linked to diabetic nephropathy (DN). ADIPOQ and SOX2 genetic polymorphisms are found to be associated with DN. In the present study, we first investigated the association between MCF2L2 and DN, and then evaluated effects of these three genes on the development of DN. 相似文献19.
Jing Shao Lishan Chen Brian Marrs Lin Lee Hai Huang Kenneth G Manton George M Martin Junko Oshima 《BMC medical genetics》2007,8(1):7
Background
The SOD2 gene encodes an antioxidant enzyme, mitochondrial superoxide dismutase. SOD2 polymorphisms are of interest because of their potential roles in the modulation of free radical-mediated macromolecular damage during aging. 相似文献20.
Katja Hölter Anne-Kathrin Wermter André Scherag Wolfgang Siegfried Hanspeter Goldschmidt Johannes Hebebrand Anke Hinney 《BMC medical genetics》2007,8(1):21